NO171857C - Analogifremgangsmaate for fremstilling av terapeutisk aktive 2'-halomethyliden-adenosin-derivater - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive 2'-halomethyliden-adenosin-derivater

Info

Publication number: NO171857C
Authority: NO; Norway
Prior art keywords: halomethylideen; preparation; therapeutic active; adenosine derivatives; analogy procedure
Prior art date: 1988-09-27

Application number

NO893826A

Other languages

English (en)

Other versions

NO171857B (no

NO893826L (no

NO893826D0 (no

Inventor

James R Mccarthy

Michael L Edwards

David M Stemerick

Esa T Jarvi

Nellikunja J Prakash

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-09-27

Filing date

1989-09-26

Publication date

1993-05-12

1989-09-26 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1989-09-26 Publication of NO893826D0 publication Critical patent/NO893826D0/no

1990-03-28 Publication of NO893826L publication Critical patent/NO893826L/no

1993-02-01 Publication of NO171857B publication Critical patent/NO171857B/no

1993-05-12 Publication of NO171857C publication Critical patent/NO171857C/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/052—Imidazole radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/056—Triazole or tetrazole radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO893826A 1988-09-27 1989-09-26 Analogifremgangsmaate for fremstilling av terapeutisk aktive 2'-halomethyliden-adenosin-derivater NO171857C (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US24991188A	1988-09-27	1988-09-27
US38939189A	1989-08-03	1989-08-03

Publications (4)

Publication Number	Publication Date
NO893826D0 NO893826D0 (no)	1989-09-26
NO893826L NO893826L (no)	1990-03-28
NO171857B NO171857B (no)	1993-02-01
NO171857C true NO171857C (no)	1993-05-12

Family

ID=26940460

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO893826A NO171857C (no)	1988-09-27	1989-09-26	Analogifremgangsmaate for fremstilling av terapeutisk aktive 2'-halomethyliden-adenosin-derivater

Country Status (18)

Country	Link
EP (1)	EP0365849B1 (no)
JP (1)	JP2968002B2 (no)
KR (1)	KR0146333B1 (no)
CN (1)	CN1046334A (no)
AR (1)	AR248283A1 (no)
AT (1)	ATE111477T1 (no)
AU (1)	AU621664B2 (no)
CA (1)	CA1336903C (no)
DE (1)	DE68918215T2 (no)
DK (1)	DK171237B1 (no)
ES (1)	ES2063796T3 (no)
FI (1)	FI94763C (no)
HU (1)	HU204843B (no)
IE (1)	IE63561B1 (no)
IL (1)	IL91773A (no)
NO (1)	NO171857C (no)
NZ (1)	NZ230766A (no)
PT (1)	PT91803B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5340816A (en) *	1990-10-18	1994-08-23	E. R. Squibb & Sons, Inc.	Hydroxymethyl(methylenecyclopentyl) purines and pyrimidines
US5206244A (en) *	1990-10-18	1993-04-27	E. R. Squibb & Sons, Inc.	Hydroxymethyl (methylenecyclopentyl) purines and pyrimidines
FR2668153B1 (fr) *	1990-10-22	1995-03-31	Pasteur Merieux Serums Vacc	Nouveaux composes ribonucleosides, leur procede de preparation et les medicaments les contenant.
US5589587A (en) *	1992-05-12	1996-12-31	Merrell Pharmaceuticals Inc.	Process for the preparation of ribonucleotide reductase inhibitors
EP0640092B1 (en) *	1992-05-12	1996-12-11	Merrell Pharmaceuticals Inc.	A process for the preparation of ribonucleotide reductase inhibitors
US5627053A (en) *	1994-03-29	1997-05-06	Ribozyme Pharmaceuticals, Inc.	2'deoxy-2'-alkylnucleotide containing nucleic acid
WO1996001834A1 (fr) *	1994-07-12	1996-01-25	Yamasa Corporation	2'-desoxy-2'-(methylidene substitue ou non substitue)-4'-thionucleoside
AU784794B2 (en) *	1999-06-09	2006-06-22	Anticancer, Inc.	Modulators of methylation for control of bacterial virulence
US6579857B1 (en)	1999-06-11	2003-06-17	Evanston Northwestern Healthcare Research Institute	Combination cancer therapy comprising adenosine and deaminase enzyme inhibitors
US20040002476A1 (en) *	2002-02-14	2004-01-01	Stuyver Lieven J.	Modified fluorinated nucleoside analogues
DK2794627T3 (en)	2011-12-22	2019-01-14	Alios Biopharma Inc	SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGUES THEREOF
USRE48171E1 (en)	2012-03-21	2020-08-25	Janssen Biopharma, Inc.	Substituted nucleosides, nucleotides and analogs thereof
US9441007B2 (en)	2012-03-21	2016-09-13	Alios Biopharma, Inc.	Substituted nucleosides, nucleotides and analogs thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL84414A0 (en) *	1986-11-14	1988-04-29	Ciba Geigy Ag	N9-cyclopentyl-substituted adenine derivatives
ATE124702T1 (de) *	1987-03-19	1995-07-15	Yamasa Shoyu Kk	2'-alkyliden-pyrimidin-nukleosid-derivate, verfahren zur herstellung und verwendung.
NZ225906A (en) *	1987-08-26	1990-10-26	Merrell Dow Pharma	Aristeromycin/adenosine derivatives and pharmaceutical compositions
ZA894534B (en) *	1988-06-20	1990-03-28	Merrell Dow Pharma	Novel neplanocin derivatives

1989
- 1989-09-22 HU HU894982A patent/HU204843B/hu not_active IP Right Cessation
- 1989-09-25 NZ NZ230766A patent/NZ230766A/en unknown
- 1989-09-25 IL IL9177389A patent/IL91773A/en not_active IP Right Cessation
- 1989-09-26 CN CN89108169A patent/CN1046334A/zh active Pending
- 1989-09-26 DE DE68918215T patent/DE68918215T2/de not_active Expired - Fee Related
- 1989-09-26 FI FI894546A patent/FI94763C/fi not_active IP Right Cessation
- 1989-09-26 DK DK473289A patent/DK171237B1/da not_active IP Right Cessation
- 1989-09-26 AU AU41760/89A patent/AU621664B2/en not_active Ceased
- 1989-09-26 NO NO893826A patent/NO171857C/no not_active IP Right Cessation
- 1989-09-26 PT PT91803A patent/PT91803B/pt not_active IP Right Cessation
- 1989-09-26 ES ES89117735T patent/ES2063796T3/es not_active Expired - Lifetime
- 1989-09-26 JP JP1250413A patent/JP2968002B2/ja not_active Expired - Fee Related
- 1989-09-26 KR KR1019890013825A patent/KR0146333B1/ko not_active IP Right Cessation
- 1989-09-26 EP EP89117735A patent/EP0365849B1/en not_active Expired - Lifetime
- 1989-09-26 IE IE308089A patent/IE63561B1/en not_active IP Right Cessation
- 1989-09-26 AR AR89315002A patent/AR248283A1/es active
- 1989-09-26 AT AT89117735T patent/ATE111477T1/de not_active IP Right Cessation
- 1989-09-27 CA CA000613429A patent/CA1336903C/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
HUT50844A (en)	1990-03-28
IL91773A0 (en)	1990-06-10
HU204843B (en)	1992-02-28
AU4176089A (en)	1990-04-05
EP0365849A2 (en)	1990-05-02
CA1336903C (en)	1995-09-05
IE893080L (en)	1990-03-27
NO171857B (no)	1993-02-01
FI94763B (fi)	1995-07-14
DE68918215D1 (de)	1994-10-20
JP2968002B2 (ja)	1999-10-25
EP0365849B1 (en)	1994-09-14
IE63561B1 (en)	1995-05-17
FI894546A0 (fi)	1989-09-26
ATE111477T1 (de)	1994-09-15
AU621664B2 (en)	1992-03-19
FI94763C (fi)	1995-10-25
CN1046334A (zh)	1990-10-24
JPH02160769A (ja)	1990-06-20
DK473289A (da)	1990-03-28
FI894546A (fi)	1990-03-28
NO893826L (no)	1990-03-28
PT91803A (pt)	1990-03-30
NO893826D0 (no)	1989-09-26
IL91773A (en)	1994-02-27
NZ230766A (en)	1992-07-28
EP0365849A3 (en)	1990-12-27
KR900004736A (ko)	1990-04-12
ES2063796T3 (es)	1995-01-16
DE68918215T2 (de)	1995-02-02
AR248283A1 (es)	1995-07-12
DK171237B1 (da)	1996-08-05
PT91803B (pt)	1995-05-31
KR0146333B1 (ko)	1998-08-01
DK473289D0 (da)	1989-09-26

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Legal Events

Date	Code	Title	Description
2001-04-30	MM1K	Lapsed by not paying the annual fees	Free format text: LAPSED IN MARCH 2001