NO167572C - Analogifremgangsmaate for fremstilling av et terapeutisk aktivt purinderivat. - Google Patents

Analogifremgangsmaate for fremstilling av et terapeutisk aktivt purinderivat.

Info

Publication number: NO167572C
Authority: NO; Norway
Prior art keywords: preparation; purine derivative; therapeutic active; analogy procedure; active purine
Prior art date: 1984-09-20

Application number

NO87874764A

Other languages

English (en)

Other versions

NO874764D0 (no

NO167572B (no

NO874764L (no

Inventor

Michael Raymond Harnden

Richard Lewis Jarvest

Original Assignee

Beecham Group Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-09-20

Filing date

1987-11-16

Publication date

1991-11-20

1984-09-20 Priority claimed from GB848423833A external-priority patent/GB8423833D0/en

1985-04-23 Priority claimed from GB858510331A external-priority patent/GB8510331D0/en

1985-08-16 Priority claimed from GB858520618A external-priority patent/GB8520618D0/en

1987-11-16 Application filed by Beecham Group Plc filed Critical Beecham Group Plc

1987-11-16 Publication of NO874764D0 publication Critical patent/NO874764D0/no

1987-11-16 Publication of NO874764L publication Critical patent/NO874764L/no

1991-08-12 Publication of NO167572B publication Critical patent/NO167572B/no

1991-11-20 Publication of NO167572C publication Critical patent/NO167572C/no

Links

150000003212 purines Chemical class 0.000 title 1
230000001225 therapeutic effect Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/007—Esters of unsaturated alcohols having the esterified hydroxy group bound to an acyclic carbon atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Virology (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Communicable Diseases (AREA)
Chemical Kinetics & Catalysis (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Biotechnology (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

NO87874764A 1984-09-20 1987-11-16 Analogifremgangsmaate for fremstilling av et terapeutisk aktivt purinderivat. NO167572C (no)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GB848423833A GB8423833D0 (en)	1984-09-20	1984-09-20	Compounds
GB858510331A GB8510331D0 (en)	1985-04-23	1985-04-23	Compounds
GB858520618A GB8520618D0 (en)	1985-08-16	1985-08-16	Compounds
PCT/GB1986/000153 WO1987005604A1 (en)	1984-09-20	1986-03-17	2-aminopurine derivatives and process for their preparation

Publications (4)

Publication Number	Publication Date
NO874764D0 NO874764D0 (no)	1987-11-16
NO874764L NO874764L (no)	1987-11-16
NO167572B NO167572B (no)	1991-08-12
NO167572C true NO167572C (no)	1991-11-20

Family

ID=27262464

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO87874764A NO167572C (no)	1984-09-20	1987-11-16	Analogifremgangsmaate for fremstilling av et terapeutisk aktivt purinderivat.

Country Status (24)

Country	Link
EP (1)	EP0182024B1 (no)
JP (2)	JPS6185388A (no)
KR (1)	KR930006349B1 (no)
AT (1)	AT389118B (no)
AU (1)	AU589371B2 (no)
BG (1)	BG61493B2 (no)
CA (1)	CA1262899A (no)
CY (1)	CY1747A (no)
CZ (1)	CZ283721B6 (no)
DE (1)	DE3582399D1 (no)
DK (1)	DK167019B1 (no)
ES (1)	ES8703876A1 (no)
FI (1)	FI87564C (no)
GR (1)	GR852272B (no)
HK (1)	HK128693A (no)
HU (1)	HU198934B (no)
IE (1)	IE58141B1 (no)
MX (1)	MX165116B (no)
MY (1)	MY102473A (no)
NL (1)	NL960006I1 (no)
NO (1)	NO167572C (no)
NZ (1)	NZ213528A (no)
PT (1)	PT81160B (no)
WO (1)	WO1987005604A1 (no)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE8406538D0 (sv) *	1984-12-21	1984-12-21	Astra Laekemedel Ab	Novel derivatives of purine
GB8628826D0 (en) *	1986-12-02	1987-01-07	Beecham Group Plc	Pharmaceutical products
EP0302644B1 (en) *	1987-08-01	1997-01-29	Beecham Group Plc	Purine compounds and their preparation
US5175288A (en) *	1987-08-01	1992-12-29	Beecham Group P.L.C.	Process for preparing purine derivatives and intermediates thereof
GB8817270D0 (en) *	1988-07-20	1988-08-24	Beecham Group Plc	Novel process
GB8817607D0 (en) *	1988-07-23	1988-09-01	Beecham Group Plc	Novel process
GB8822236D0 (en) *	1988-09-21	1988-10-26	Beecham Group Plc	Chemical process
CA2009109A1 (en) *	1989-02-02	1990-08-02	John Hannah	Antiviral acyclonucleosides and acyclonucleotides
CA2009110A1 (en) *	1989-02-02	1990-08-02	Richard L. Tolman	Cyclic monophosphates of purine and pyrimidine acyclonucleosides
GB8904855D0 (en) *	1989-03-03	1989-04-12	Beecham Group Plc	Pharmaceutical treatment
GB8922076D0 (en) *	1989-09-28	1989-11-15	Beecham Group Plc	Novel process
GB9004647D0 (en) *	1990-03-01	1990-04-25	Beecham Group Plc	Pharmaceuticals
GB9102127D0 (en) *	1991-01-31	1991-03-13	Smithkline Beecham Plc	Pharmaceuticals
GB9201961D0 (en)	1992-01-30	1992-03-18	Smithkline Beecham Plc	Pharmaceuticals
US6124304A (en) *	1993-10-05	2000-09-26	Smithkline Beecham Plc	Penciclovir for the treatment of zoster associated pain
IL111138A (en) *	1993-10-05	1997-04-15	Smithkline Beecham Plc	Pharmaceutical compositions comprising penciclovir and/or its bioprecursor and/or its derivatives for the treatment and prophylaxis of post-herpetic neuralgia
GB9326177D0 (en) *	1993-12-22	1994-02-23	Smithkline Beecham Plc	Pharmaceuticals
GB9323403D0 (en) *	1993-11-12	1994-01-05	Smithkline Beecham Plc	Pharmaceuticals
GB9323404D0 (en) *	1993-11-12	1994-01-05	Smithkline Beecham Plc	Pharmaceuticals
US6683084B1 (en)	1993-11-12	2004-01-27	Novartis International Pharmaceutical Ltd.	Use of 2-amino purine derivatives for the treatment and prophylaxis of human herpes virus 6 infections
GB9402161D0 (en)	1994-02-04	1994-03-30	Wellcome Found	Chloropyrimidine intermediates
GB9407698D0 (en)	1994-04-19	1994-06-15	Smithkline Beecham Plc	Pharmaceuticals
DE4420751A1 (de) *	1994-06-15	1995-12-21	Basf Ag	Verfahren zur Herstellung von enantiomerenreinen Lactamen
MX9702488A (es) *	1994-10-05	1998-04-30	Darwin Discovery Ltd	Compuestos de purina y guanina como inhibidores de pnp.
GB9504497D0 (en) *	1995-03-07	1995-04-26	Smithkline Beecham Plc	Pharmaceuticals
GB9600847D0 (en) *	1996-01-16	1996-03-20	Smithkline Beecham Plc	Pharmaceuticals
DE69706833T2 (de) *	1996-02-07	2002-04-11	Novartis Int Pharm Ltd	Pharmazeutische zusammensetzungen enthaltend famciclovir monohydrat
US7279483B2 (en)	1996-02-07	2007-10-09	Novartis Ag	Famciclovir monohydrate
AT412211B (de) *	1996-07-20	2004-11-25	Novartis Int Pharm Ltd	Verfahren zur herstellung von penciclovir und famciclovir
GB9615253D0 (en) *	1996-07-20	1996-09-04	Smithkline Beecham Plc	Pharmaceuticals
GB9615276D0 (en) *	1996-07-20	1996-09-04	Smithkline Beecham Plc	Pharmaceuticals
CA2251481A1 (en)	1997-11-12	1999-05-12	Junichi Yasuoka	Purine derivatives having cyclopropane ring
GB9807116D0 (en)	1998-04-02	1998-06-03	Smithkline Beecham Plc	Novel process
SI20022A (sl) *	1998-07-29	2000-02-29	Kemijski inštitut	Alkilno substituirani purinovi derivati in njihova priprava
WO2003079972A2 (en)	2002-02-22	2003-10-02	New River Parmaceuticals Inc.	Active agent delivery systems and methods for protecting and administering active agents
EP1532151A2 (en)	2002-08-26	2005-05-25	Teva Pharmaceutical Industries Limited	Crystalline solid famciclovir forms i, ii, iii and preparation thereof
AU2004206821C1 (en)	2003-01-14	2009-10-01	Gilead Sciences, Inc.	Compositions and methods for combination antiviral therapy
AU2006230269A1 (en)	2005-03-30	2006-10-05	Novartis Ag	Penciclovir or famciclovir for the treatment of recurrent genital herpes with a one-day application
GB2426247A (en) *	2005-05-20	2006-11-22	Arrow Int Ltd	Methods of preparing purine derivatives such as famciclovir
TWI471145B (zh)	2005-06-13	2015-02-01	Bristol Myers Squibb & Gilead Sciences Llc	單一式藥學劑量型
TWI375560B (en)	2005-06-13	2012-11-01	Gilead Sciences Inc	Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same
EP3337512A1 (en)	2015-08-17	2018-06-27	Sanovel Ilac Sanayi ve Ticaret A.S.	A topical antiviral composition
US10364263B2 (en) *	2015-12-08	2019-07-30	Retrophin, Inc.	Cyclic phosphates and cyclic phosphoramidates for the treatment of neurologic disorders
US20230218644A1 (en)	2020-04-16	2023-07-13	Som Innovation Biotech, S.A.	Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NO161116C (no) *	1982-10-14	1989-07-05	Wellcome Found	Analogifremgangsmaate for fremstilling av antiviralt virksomme purinderivater.
DE3485225D1 (de) *	1983-08-18	1991-12-05	Beecham Group Plc	Antivirale guanin-derivate.
AU577303B2 (en) *	1983-08-18	1988-09-22	Novartis International Pharmaceutical Ltd	9-substituted-2-amino purines
DE3571810D1 (en) *	1984-01-26	1989-08-31	Merck & Co Inc	Substituted butyl guanines and their utilization in antiviral compositions

1985
- 1985-09-09 DE DE8585111354T patent/DE3582399D1/de not_active Expired - Lifetime
- 1985-09-09 EP EP85111354A patent/EP0182024B1/en not_active Expired - Lifetime
- 1985-09-18 AU AU47560/85A patent/AU589371B2/en not_active Expired
- 1985-09-18 PT PT81160A patent/PT81160B/pt unknown
- 1985-09-18 CA CA000491028A patent/CA1262899A/en not_active Expired
- 1985-09-18 IE IE230785A patent/IE58141B1/en not_active IP Right Cessation
- 1985-09-18 NZ NZ213528A patent/NZ213528A/xx unknown
- 1985-09-18 GR GR852272A patent/GR852272B/el unknown
- 1985-09-18 DK DK424685A patent/DK167019B1/da not_active IP Right Cessation
- 1985-09-19 JP JP60207693A patent/JPS6185388A/ja active Granted
- 1985-09-19 ES ES547128A patent/ES8703876A1/es not_active Expired
- 1985-10-01 MX MX9010A patent/MX165116B/es unknown
1986
- 1986-03-17 WO PCT/GB1986/000153 patent/WO1987005604A1/en active IP Right Grant
- 1986-03-17 KR KR1019870701056A patent/KR930006349B1/ko not_active IP Right Cessation
- 1986-03-17 HU HU863048A patent/HU198934B/hu unknown
- 1986-03-17 AT AT0904286A patent/AT389118B/de not_active IP Right Cessation
1987
- 1987-09-29 MY MYPI87002221A patent/MY102473A/en unknown
- 1987-11-16 NO NO87874764A patent/NO167572C/no unknown
- 1987-11-16 FI FI875059A patent/FI87564C/fi not_active IP Right Cessation
1991
- 1991-12-19 CZ CS913915A patent/CZ283721B6/cs not_active IP Right Cessation
1993
- 1993-05-07 JP JP5130044A patent/JPH0826021B2/ja not_active Expired - Lifetime
- 1993-11-10 BG BG98209A patent/BG61493B2/bg unknown
- 1993-11-18 HK HK1286/93A patent/HK128693A/xx not_active IP Right Cessation
1994
- 1994-06-03 CY CY174794A patent/CY1747A/xx unknown
1996
- 1996-04-09 NL NL960006C patent/NL960006I1/nl unknown

Also Published As

Publication number	Publication date
MY102473A (en)	1992-06-30
WO1987005604A1 (en)	1987-09-24
GR852272B (no)	1986-01-21
JPH0625241A (ja)	1994-02-01
DK424685D0 (da)	1985-09-18
DK167019B1 (da)	1993-08-16
NO874764D0 (no)	1987-11-16
CS391591A3 (en)	1992-05-13
HUT47576A (en)	1989-03-28
NZ213528A (en)	1989-03-29
JPS6185388A (ja)	1986-04-30
FI87564B (fi)	1992-10-15
EP0182024A3 (en)	1989-03-08
MX165116B (es)	1992-10-27
EP0182024B1 (en)	1991-04-03
JPH0586792B2 (no)	1993-12-14
HU198934B (en)	1989-12-28
FI87564C (fi)	1993-01-25
FI875059A0 (fi)	1987-11-16
FI875059A (fi)	1987-11-16
IE58141B1 (en)	1993-07-14
PT81160B (pt)	1988-01-22
EP0182024A2 (en)	1986-05-28
ES547128A0 (es)	1987-03-01
DE3582399D1 (de)	1991-05-08
AT389118B (de)	1989-10-25
NL960006I2 (nl)	1996-09-02
CY1747A (en)	1994-06-03
AU589371B2 (en)	1989-10-12
KR930006349B1 (ko)	1993-07-14
NO167572B (no)	1991-08-12
NL960006I1 (nl)	1996-09-02
NO874764L (no)	1987-11-16
JPH0826021B2 (ja)	1996-03-13
ES8703876A1 (es)	1987-03-01
CA1262899A (en)	1989-11-14
DK424685A (da)	1986-03-21
HK128693A (en)	1993-11-26
CZ283721B6 (cs)	1998-06-17
BG61493B2 (bg)	1997-09-30
AU4756085A (en)	1986-03-27
IE852307L (en)	1986-03-20
PT81160A (en)	1985-10-01
ATA904286A (de)	1989-03-15

Publication	Publication Date	Title
NO167572C (no)	1991-11-20	Analogifremgangsmaate for fremstilling av et terapeutisk aktivt purinderivat.
NO164653C (no)	1990-11-07	Analogifremgangsmaate for fremstilling av et terapeutisk aktivt indol-derivat.
NO164025C (no)	1990-08-22	Analogifremgangsmaate for fremstilling av terapeutisk aktive 3-imidazolylmetyl-tetrahydrokarbazolon-derivater.
NO851949L (no)	1985-11-18	Analogifremgangsmaate for fremstilling av terapeutisk aktive aminotetralinderivater.
NO162514C (no)	1990-01-10	Analogifremgangsmaate for fremstilling av terapeutisk aktive kinonderivater.
NO163406C (no)	1990-05-23	Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazokinolinonderivater.
NO161372C (no)	1989-08-09	Analogifremgangsmaate for fremstilling av terapeutisk aktive guaninderivater.
NO862477D0 (no)	1986-06-20	Analogifremgangsmaate for fremstilling av terapeutisk aktive 2-arylimidazol-derivater.
NO164097C (no)	1990-08-29	Analogifremgangsmaate for fremstilling av terapeutisk aktive 2-(n-substituert-guanidino)-4-hetero-aryl-tiazol-derivater.
NO161497C (no)	1989-08-23	Analogifremgangsmaate for fremstilling av terapeutisk aktive 9a-aza-9a-homoerytromycin-derivater.
NO864879L (no)	1987-06-09	Fremgangsmaate for fremstilling av terapeutisk aktive tiazolforbindelser.
NO168355C (no)	1992-02-12	Analogifremgangsmaate for fremstilling av terapeutisk aktive benzimidazolderivater
NO159086C (no)	1988-11-30	Analogifremgangsmaate ved fremstilling av et terapeutisk aktivt triazolderivat.
NO167797C (no)	1991-12-11	Analogifremgangsmaate for fremstilling av et terapeutisk aktivt nitrometan.
NO164541C (no)	1990-10-17	Analogifremgangsmaate for fremstilling av terapeutisk aktive benzimidazolderivater.
NO163954C (no)	1990-08-15	Analogifremgangsmaate for fremstilling av et terapeutisk aktivt amidinderivat.
NO164897C (no)	1990-11-28	Analogifremgangsmaate for fremstilling av terapeutisk aktive oxazolidinonderivater.
NO159591C (no)	1989-01-18	Analogifremgangsmaate for fremstilling av et terapeutisk aktivt karbostyrilderivat.
NO862372D0 (no)	1986-06-13	Fremgangsmaate for fremstilling av terapeutisk aktive kinolonderivater.
NO168100C (no)	1992-01-15	Analogifremgangsmaate for fremstilling av et terapeutisk aktivt fenolderivat
NO165069C (no)	1990-12-19	Analogifremgangsmaate for fremstilling av terapeutisk aktive cyklopentyletere.
NO161313C (no)	1989-08-02	Analogifremgangsmaate ved fremstilling av terapeutisk aktive fluorallylaminderivater.
NO865028D0 (no)	1986-12-12	Fremgangsmaate for fremstilling av et terapeutisk system.
NO167802C (no)	1991-12-11	Analogifremgangsmaate for fremstilling av terapeutisk aktive benzotiazepinderivater.
NO162188C (no)	1989-11-29	Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazokinoliner.