NO165959C - ANALOGY PROCEDURE FOR THE PREPARATION OF 3,5-DISUBSTITUTED PYROCATIC COLD DERIVATIVES. - Google Patents
ANALOGY PROCEDURE FOR THE PREPARATION OF 3,5-DISUBSTITUTED PYROCATIC COLD DERIVATIVES.Info
- Publication number
- NO165959C NO165959C NO870984A NO870984A NO165959C NO 165959 C NO165959 C NO 165959C NO 870984 A NO870984 A NO 870984A NO 870984 A NO870984 A NO 870984A NO 165959 C NO165959 C NO 165959C
- Authority
- NO
- Norway
- Prior art keywords
- pyrocatic
- disubstituted
- preparation
- analogy procedure
- derivatives
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
- C07C201/06—Preparation of nitro compounds
- C07C201/08—Preparation of nitro compounds by substitution of hydrogen atoms by nitro groups
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
- C07C45/298—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with manganese derivatives
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/30—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/30—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation
- C07C45/305—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation with halogenochromate reagents, e.g. pyridinium chlorochromate
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/56—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing hydroxy groups
- C07C47/565—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing hydroxy groups all hydroxy groups bound to the ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
- C07C49/83—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups polycyclic
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/017—Esters of hydroxy compounds having the esterified hydroxy group bound to a carbon atom of a six-membered aromatic ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/16—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/15—Six-membered rings
- C07D285/16—Thiadiazines; Hydrogenated thiadiazines
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH98086 | 1986-03-11 | ||
CH6287 | 1987-01-09 |
Publications (4)
Publication Number | Publication Date |
---|---|
NO870984D0 NO870984D0 (en) | 1987-03-10 |
NO870984L NO870984L (en) | 1987-09-14 |
NO165959B NO165959B (en) | 1991-01-28 |
NO165959C true NO165959C (en) | 1991-05-08 |
Family
ID=25683401
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO870984A NO165959C (en) | 1986-03-11 | 1987-03-10 | ANALOGY PROCEDURE FOR THE PREPARATION OF 3,5-DISUBSTITUTED PYROCATIC COLD DERIVATIVES. |
NO1998006C NO1998006I1 (en) | 1986-03-11 | 1998-01-28 | Tolcapone |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO1998006C NO1998006I1 (en) | 1986-03-11 | 1998-01-28 | Tolcapone |
Country Status (22)
Country | Link |
---|---|
EP (1) | EP0237929B1 (en) |
JP (1) | JPH0742254B2 (en) |
AR (1) | AR245097A1 (en) |
AT (1) | ATE90072T1 (en) |
AU (1) | AU603788B2 (en) |
CA (1) | CA1302418C (en) |
CS (1) | CS402291A3 (en) |
DE (1) | DE3786026D1 (en) |
DK (1) | DK175069B1 (en) |
ES (1) | ES2056792T3 (en) |
FI (1) | FI91396C (en) |
HK (1) | HK165896A (en) |
HU (1) | HU201900B (en) |
IE (1) | IE61316B1 (en) |
IL (1) | IL81791A (en) |
LU (1) | LU90219I2 (en) |
LV (1) | LV5742B4 (en) |
MC (1) | MC1807A1 (en) |
NL (1) | NL970041I1 (en) |
NO (2) | NO165959C (en) |
NZ (1) | NZ219496A (en) |
PT (1) | PT84449B (en) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5283352A (en) * | 1986-11-28 | 1994-02-01 | Orion-Yhtyma Oy | Pharmacologically active compounds, methods for the preparation thereof and compositions containing the same |
FI864875A0 (en) * | 1986-11-28 | 1986-11-28 | Orion Yhtymae Oy | NYA FARMAKOLOGISKT AKTIVA FOERENINGAR, DESSA INNEHAOLLANDE KOMPOSITIONER SAMT FOERFARANDE OCH MELLANPRODUKTER FOER ANVAENDNING VID FRAMSTAELLNING AV DESSA. |
YU213587A (en) * | 1986-11-28 | 1989-06-30 | Orion Yhtymae Oy | Process for obtaining new pharmacologic active cateholic derivatives |
US5489614A (en) * | 1987-11-27 | 1996-02-06 | Orion-Yhtyma Oy | Catechol derivatives, their physiologically acceptable salts, esters and use |
MTP1031B (en) * | 1987-12-24 | 1990-10-04 | Orion Yhtymae Oy | New use of cathecol-o-methyl transferase (comt) inhibitors and their physiologically acceptable salts and esters |
GB9113431D0 (en) * | 1991-06-20 | 1991-08-07 | Orion Yhytma Oy | Method for the preparation of 3,4-dihydroxy-5-nitrobenzaldehyde |
GB9419274D0 (en) * | 1994-09-23 | 1994-11-09 | Orion Yhtymae Oy | New method for the preparation of 3,4-dihydroxy-5-nitrobenzaldehyde |
GB9626472D0 (en) | 1996-12-20 | 1997-02-05 | Aperia Anita C | New use of comt inhibitors |
ID19540A (en) * | 1997-01-22 | 1998-07-23 | Hoffmann La Roche | METHOD OF MAKING BENZOFENON DECREASES |
GB9819382D0 (en) * | 1998-09-04 | 1998-10-28 | Cerebrus Ltd | Chemical compounds I |
GB2344819A (en) | 1998-12-18 | 2000-06-21 | Portela & Ca Sa | 2-Phenyl-1-(3,4-dihydroxy-5-nitrophenyl)-1-ethanones |
DE19960105A1 (en) * | 1999-12-14 | 2001-06-21 | Haarmann & Reimer Gmbh | Catechol oximes and their use in cosmetic and dermatological preparations |
FI20000635A0 (en) * | 2000-03-17 | 2000-03-17 | Orion Yhtymae Oyj | Use of COMT inhibitors as an analgesic |
WO2001087857A1 (en) * | 2000-05-16 | 2001-11-22 | Nippon Soda Co., Ltd. | Phenyloxazole compounds and fungicides for agricultural and horticultural use |
GB0015228D0 (en) * | 2000-06-21 | 2000-08-16 | Portela & Ca Sa | Substituted nitrated catechols, their use in the treatment of some central and peripheral nervous system disorders |
GB2363792A (en) * | 2000-06-21 | 2002-01-09 | Portela & Ca Sa | Nitrocatechols |
FI20012242A0 (en) * | 2001-11-19 | 2001-11-19 | Orion Corp | New pharmaceutical compounds |
US20060105036A1 (en) | 2003-05-12 | 2006-05-18 | Stephen Peroutka | Threo-dops controlled release formulation |
US8158149B2 (en) | 2004-05-12 | 2012-04-17 | Chelsea Therapeutics, Inc. | Threo-DOPS controlled release formulation |
WO2005110462A2 (en) | 2004-05-04 | 2005-11-24 | Children's Medical Center Corporation | Methods and compositions for treatment of preeclampsia |
DE102004023332A1 (en) * | 2004-05-12 | 2006-01-19 | Bayer Cropscience Gmbh | Quinoxaline-2-one derivatives, crop protection agents containing them, and processes for their preparation and their use |
US20060173074A1 (en) | 2004-11-10 | 2006-08-03 | Juha Ellmen | Treatment of restless legs syndrome |
AR058439A1 (en) | 2005-07-26 | 2008-02-06 | Portela & Ca Sa | NITROCATECOL DERIVATIVES AS COMT INHIBITORS PROCESSES OF OBTAINING AND PHARMACEUTICAL COMPOSITIONS. |
EP1845097A1 (en) * | 2006-04-10 | 2007-10-17 | Portela & Ca., S.A. | Oxadiazole derivatives as COMT inhibitors |
ATE548034T1 (en) | 2006-06-28 | 2012-03-15 | Chelsea Therapeutics Inc | PHARMACEUTICAL COMPOSITIONS CONTAINING DROXIDOPA |
CA2670134A1 (en) | 2006-11-21 | 2008-08-28 | Beth Israel Deaconess Medical Center | Hypoxia related genes and proteins for the treatment and diagnosis of pregnancy related complications |
HUE031317T2 (en) | 2007-01-31 | 2017-07-28 | Bial - Portela & Ca S A | Nitrocatechol derivates as COMT inhibitors administered with a specific dosage regime |
WO2008112562A1 (en) | 2007-03-09 | 2008-09-18 | Chelsea Therapeutics, Inc. | Droxidopa and pharmaceutical composition thereof for the treatment of fibromyalgia |
EP2514417A3 (en) | 2007-05-07 | 2013-01-30 | Chelsea Therapeutics, Inc. | Droxidopa and pharmaceutical composition thereof for the treatment of mood disorders, sleep disorders, or attention deficit disorders |
JP2009126784A (en) * | 2007-11-19 | 2009-06-11 | Mitsubishi Gas Chem Co Inc | Method for producing 2-iodo-3,4-dimethoxybenzonitrile |
CN101965339B (en) | 2007-12-25 | 2013-08-14 | 橘生药品工业株式会社 | Catechol derivative, pharmaceutical composition containing the same, use of catechol derivative, and use of pharmaceutical composition |
BRPI0908731A2 (en) | 2008-03-17 | 2017-05-16 | Bial - Portela & C A S A | 5- [3- (2,5-Dichloro-4,6-dimethyl-1-oxy-pyridin-3-yl) [1,2,4] oxadiazol-5-yl] -3-nitrobenzene-1 crystalline forms 2-diol |
CA2729405C (en) | 2008-07-04 | 2016-08-02 | Kissei Pharmaceutical Co., Ltd. | Novel catechol derivative, pharmaceutical composition containing the same, use of the catechol derivative, and use of the pharmaceutical composition |
RU2701731C2 (en) | 2009-04-01 | 2019-10-01 | Биал-Портела Энд Ка, С.А. | Pharmaceutical preparations containing nitro catechine derivatives, and methods for preparing thereof |
JP5707063B2 (en) * | 2009-06-18 | 2015-04-22 | キッセイ薬品工業株式会社 | Novel catechol derivatives, pharmaceutical compositions containing them, and uses thereof |
JP5529639B2 (en) * | 2009-06-18 | 2014-06-25 | キッセイ薬品工業株式会社 | Novel catechol-O-methyltransferase inhibitor |
BR112012018256A8 (en) | 2010-03-04 | 2017-12-19 | Orion Corp | Parkinson's disease treatment method |
US20140045900A1 (en) | 2011-02-11 | 2014-02-13 | Bial-Portela & Ca, S.A. | Administration regime for nitrocatechols |
JP5880913B2 (en) | 2011-05-17 | 2016-03-09 | 三郎 佐古田 | Treatment for trunk symptoms (postural reflex abnormalities) in Parkinson's disease |
ES2960805T3 (en) | 2011-12-13 | 2024-03-06 | Bial Portela & Ca Sa | Chemical compound useful as an intermediate to prepare a catechol-o-methyltransferase inhibitor |
US20130197090A1 (en) | 2012-01-31 | 2013-08-01 | Chelsea Therapeutics, Inc. | Postural stability and incident functions in patients |
US9109005B2 (en) * | 2012-02-23 | 2015-08-18 | Boehringer Ingelheim International Gmbh | Method for manufacturing of ciclesonide |
TWI638802B (en) * | 2012-05-24 | 2018-10-21 | 芬蘭商奧利安公司 | Catechol o-methyltransferase activity inhibiting compounds |
WO2014147464A2 (en) * | 2013-03-20 | 2014-09-25 | Ra Chem Pharma Limited | Novel process for the preparation of tolcapone |
RU2017120184A (en) | 2014-11-28 | 2018-12-28 | БИАЛ - ПОРТЕЛА ЭНД Ка, С.А. | DRUGS TO DELAY THE COURSE OF PARKINSON'S DISEASE |
KR20180101416A (en) | 2015-12-24 | 2018-09-12 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | CFTR modulators and methods for their use |
JP2020158391A (en) * | 2017-06-13 | 2020-10-01 | 株式会社富士薬品 | Novel nitrocatechol derivative |
BR112020020351A2 (en) | 2018-04-05 | 2021-01-12 | Calasia Pharmaceuticals, Inc. | PHARMACOLOGICAL AGENTS FOR THE TREATMENT OF EYE DISEASES |
WO2022150962A1 (en) * | 2021-01-12 | 2022-07-21 | Westlake Pharmaceutical (Hangzhou) Co., Ltd. | Protease inhibitors, preparation, and uses thereof |
CN114560771B (en) * | 2022-03-07 | 2023-10-27 | 中北大学 | Method for photocatalytic selective nitration of bromophenol |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS54128542A (en) * | 1978-03-27 | 1979-10-05 | Ube Ind Ltd | Preparation of 3-cyanocatechol derivative |
GB2038819B (en) * | 1978-12-21 | 1983-02-16 | Secr Defence | Initiatory explosives comprising a lead salt of 3,5-dinitro-catechol |
DE3484048D1 (en) * | 1983-10-25 | 1991-03-07 | Fisons Plc | PHENYLETHYLAMINE, METHOD FOR THE PRODUCTION THEREOF AND COMPOSITIONS CONTAINING THE SAME. |
DE3406329A1 (en) * | 1984-02-22 | 1985-08-22 | Merck Patent Gmbh, 6100 Darmstadt | PYRIDONE |
CA1339860C (en) * | 1985-06-17 | 1998-05-12 | Tsunehiko Soga | Derivatives of penem |
-
1987
- 1987-02-18 DK DK198700820A patent/DK175069B1/en not_active IP Right Cessation
- 1987-02-20 CA CA000530171A patent/CA1302418C/en not_active Expired - Lifetime
- 1987-03-04 NZ NZ219496A patent/NZ219496A/en unknown
- 1987-03-05 IL IL81791A patent/IL81791A/en not_active IP Right Cessation
- 1987-03-06 AU AU69764/87A patent/AU603788B2/en not_active Expired
- 1987-03-09 AR AR87306966A patent/AR245097A1/en active
- 1987-03-09 HU HU87989A patent/HU201900B/en unknown
- 1987-03-09 MC MC871876A patent/MC1807A1/en unknown
- 1987-03-10 IE IE60987A patent/IE61316B1/en not_active IP Right Cessation
- 1987-03-10 FI FI871041A patent/FI91396C/en not_active IP Right Cessation
- 1987-03-10 NO NO870984A patent/NO165959C/en not_active IP Right Cessation
- 1987-03-11 JP JP62056411A patent/JPH0742254B2/en not_active Expired - Lifetime
- 1987-03-11 PT PT84449A patent/PT84449B/en unknown
- 1987-03-11 DE DE8787103469T patent/DE3786026D1/en not_active Expired - Lifetime
- 1987-03-11 ES ES87103469T patent/ES2056792T3/en not_active Expired - Lifetime
- 1987-03-11 EP EP87103469A patent/EP0237929B1/en not_active Expired - Lifetime
- 1987-03-11 AT AT87103469T patent/ATE90072T1/en active
-
1991
- 1991-12-23 CS CS914022A patent/CS402291A3/en unknown
-
1996
- 1996-05-29 LV LV960162A patent/LV5742B4/en unknown
- 1996-09-05 HK HK165896A patent/HK165896A/en not_active IP Right Cessation
-
1997
- 1997-11-21 NL NL970041C patent/NL970041I1/en unknown
-
1998
- 1998-01-28 NO NO1998006C patent/NO1998006I1/en unknown
- 1998-02-25 LU LU90219C patent/LU90219I2/en unknown
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