NO154346C - Analogifremgangsmaate for fremstilling av terapeutisk aktive ftalazin-4-yl-eddiksyrederivater. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive ftalazin-4-yl-eddiksyrederivater.

Info

Publication number: NO154346C
Authority: NO; Norway
Prior art keywords: phtalazin; preparation; acetic acid; acid derivatives; therapeutically active
Prior art date: 1977-12-29

Application number

NO784397A

Other languages

English (en)

Other versions

NO154346B (no

NO784397L (no

Inventor

David Robert Brittain

Robin Wood

Original Assignee

Ici Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-12-29

Filing date

1978-12-28

Publication date

1986-09-03

1978-12-28 Application filed by Ici Ltd filed Critical Ici Ltd

1979-07-02 Publication of NO784397L publication Critical patent/NO784397L/no

1986-05-26 Publication of NO154346B publication Critical patent/NO154346B/no

1986-09-03 Publication of NO154346C publication Critical patent/NO154346C/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Diabetes (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Endocrinology (AREA)
Obesity (AREA)
Emergency Medicine (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

NO784397A 1977-12-29 1978-12-28 Analogifremgangsmaate for fremstilling av terapeutisk aktive ftalazin-4-yl-eddiksyrederivater. NO154346C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB5414277		1977-12-29

Publications (3)

Publication Number	Publication Date
NO784397L NO784397L (no)	1979-07-02
NO154346B NO154346B (no)	1986-05-26
NO154346C true NO154346C (no)	1986-09-03

Family

ID=10470067

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO784397A NO154346C (no)	1977-12-29	1978-12-28	Analogifremgangsmaate for fremstilling av terapeutisk aktive ftalazin-4-yl-eddiksyrederivater.

Country Status (31)

Country	Link
US (2)	US4251528A (no)
EP (1)	EP0002895B1 (no)
JP (2)	JPS5495582A (no)
AT (1)	AT365581B (no)
AU (1)	AU516264B2 (no)
BG (1)	BG34336A3 (no)
CA (1)	CA1107732A (no)
CS (1)	CS241015B2 (no)
CY (1)	CY1219A (no)
DD (1)	DD141021A5 (no)
DE (1)	DE2861170D1 (no)
DK (1)	DK151253C (no)
ES (1)	ES476496A1 (no)
FI (1)	FI64357C (no)
GR (1)	GR65303B (no)
HK (1)	HK22484A (no)
HU (1)	HU182585B (no)
IE (1)	IE47592B1 (no)
IL (1)	IL56099A0 (no)
IN (1)	IN150196B (no)
IT (1)	IT1110885B (no)
MY (1)	MY8500359A (no)
NO (1)	NO154346C (no)
NZ (1)	NZ189034A (no)
PH (1)	PH15435A (no)
PL (1)	PL118443B1 (no)
PT (1)	PT68956A (no)
SG (1)	SG68683G (no)
SU (3)	SU1087075A3 (no)
YU (3)	YU41607B (no)
ZW (1)	ZW24978A1 (no)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
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IE47592B1 (en) *	1977-12-29	1984-05-02	Ici Ltd	Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture
CA1143733A (en) *	1979-07-31	1983-03-29	Masao Yoshida	Producing 7-alkoxycarbonyl-6,8-dimethyl-4- hydroxymethyl-1-phthalazone and intermediates
US4762839A (en) *	1985-06-06	1988-08-09	Tanabe Seiyaku Co., Ltd.	Quinazolinone copmpounds useful for the prophyloxis and treatment of diabetic complications
DE3684410D1 (de) *	1985-11-07	1992-04-23	Pfizer	Heterocyclische oxophthalazinylessigsaeure.
JPS63132889A (ja) *	1986-11-21	1988-06-04	Tanabe Seiyaku Co Ltd	キナゾリノン誘導体
US5011840A (en) *	1986-11-24	1991-04-30	Pfizer Inc.	Imidazolidinedione derivatives in diabetes treatment
GB8704569D0 (en) *	1987-02-26	1987-04-01	Ici America Inc	Therapeutic agent
US4868301A (en) *	1987-06-09	1989-09-19	Pfizer Inc.	Processes and intermediates for the preparation of oxophthalazinyl acetic acids having benzothiazole or other heterocyclic side chains
JPH0676391B2 (ja) *	1987-06-09	1994-09-28	フアイザー・インコーポレイテツド	ベンゾチアゾール等の複素環側鎖を有するオキソフタラジニル酢酸類の製造方法
DK607188A (da) *	1987-11-02	1989-06-22	Merck & Co Inc	Tablet indeholdende en phthalazineddikesyreforbindelse
EP0315249A1 (en) *	1987-11-02	1989-05-10	Merck & Co. Inc.	Phthalazineacetic acid composition and tablet
US4880928A (en) *	1987-12-21	1989-11-14	Merck & Co., Inc.	Process for the preparation of 3-((4-bromo-2-fluorophenyl)methyl)-3,4-dihydro-4-oxo-1-phthalazine-acetic acid
US4940791A (en) *	1988-02-29	1990-07-10	Pfizer Inc.	Process for the production of phthalazineacetic acid ester derivatives and a novel hydrazine containing intermediate
US4904782A (en) *	1988-02-29	1990-02-27	Pfizer Inc.	Process for the production of phthalazineacetic acid ester derivatives and a novel intermediate
US4954629A (en) *	1989-05-11	1990-09-04	Pfizer Inc.	Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof
US4996204A (en) *	1989-05-11	1991-02-26	Pfizer Inc.	Pyrido[2,3-d]pyridazinones as aldose reductase inhibitors
EP0397930A1 (en) *	1989-05-18	1990-11-22	Merck & Co. Inc.	Process for the preparation of 3-[(4-bromo-2-fluorophenyl) methyl]-3,4-dihydro-4-oxo-1-phthalazineacetic acid
FR2647676A1 (fr) *	1989-06-05	1990-12-07	Union Pharma Scient Appl	Nouveaux derives de pyridazinone, leurs procedes de preparation, medicaments les contenant, utiles notamment comme inhibiteurs de l'aldose reductase
WO1991009019A1 (en) *	1989-12-15	1991-06-27	Pfizer Inc.	Substituted oxophthalazinyl acetic acids and analogs thereof
US5037831A (en) *	1990-05-21	1991-08-06	American Home Products Corporation	Spiro-isoquinoline-pyrrolidines and analogs thereof useful as aldose reductase inhibitors
FR2682108B1 (fr) *	1991-10-07	1994-01-07	Lipha	Acide 3,4-dihydro-4-oxo-3(prop-2-enyl)-1-phtalazineacetiques et derives, leurs preparations et medicaments les contenant.
KR950703539A (ko) *	1992-09-28	1995-09-20	알렌 제이. 스피겔	당뇨병 합병증 치료용 치환된 피리미딘(substituted pyrimidines for control or diabetic complications)
WO1994010151A1 (en) *	1992-11-02	1994-05-11	Merck & Co., Inc.	Substituted phthalazinones as nerotensin antagonists
CH683965A5 (it) *	1993-02-19	1994-06-30	Limad Marketing Exp & Imp	Composti della classe dei ftalidrazidici come sostanza attiva in agenti antinfiammatori ed antitossici.
AU7195594A (en) *	1993-07-26	1995-02-20	Fujisawa Pharmaceutical Co., Ltd.	Oxophthalazines for treating cachexia
US6696407B1 (en)	1997-03-21	2004-02-24	The Regents Of The University Of California	Huntington's disease treatment comprising administering aldose reductase inhibitors to increase striatal CNTF
AU6473898A (en) *	1997-03-21	1998-10-20	Regents Of The University Of California, The	Methods for modulating neurotrophic factor-associated activity using aldose reductase inhibitors
JP3553086B2 (ja) *	1997-04-15	2004-08-11	シーエスアイアール	食欲抑制活性を有する医薬組成物
OA11622A (en) *	1998-03-31	2004-09-16	Inst For Pharm Discovery Inc	Substituted indolealkanoic acids.
TNSN99224A1 (fr)	1998-12-01	2005-11-10	Inst For Pharm Discovery Inc	Methodes de reduction des niveaux de glucose et triglyceride en serum et pour suppression de l'antigenese utilisant les acides la indolealkanoique
GB2355657B (en) *	1999-10-27	2004-07-28	Phytopharm Plc	Inhibitors Of Gastric Acid Secretion
DE19963607B4 (de) *	1999-12-23	2005-12-15	Schering Ag	Verfahren zur Herstellung von 4-(Heteroaryl-methyl) halogen-1(2H)-phthalazinonen
GB2363985B (en) *	2000-06-30	2004-09-29	Phytopharm Plc	Extracts,compounds & pharmaceutical compositions having anti-diabetic activity and their use
EA200300433A1 (ru) *	2000-11-30	2003-10-30	Пфайзер Продактс Инк.	Комбинация гамк-агонистов и ингибиторов альдегидредуктазы
EP1236720B1 (en)	2001-02-28	2005-06-15	Pfizer Products Inc.	Sulfonyl pyridazinone compounds useful as aldose reductase inhibitors
ATE348100T1 (de)	2001-03-30	2007-01-15	Pfizer Prod Inc	Zwischenprodukten für die herstellung von pyridazinon aldose reductase inhibitoren.
HUP0303920A3 (en) *	2001-04-30	2004-07-28	Pfizer Prod Inc	Pharmaceutical compositions containing combinations of aldose reductase inhibitor pyridazinons and cyclooxygenase 2 inhibitors
AU761191B2 (en)	2001-05-24	2003-05-29	Pfizer Products Inc.	Therapies for tissue damage resulting from ischemia
WO2003092696A1 (en) *	2002-04-30	2003-11-13	Novartis Ag	Method for decreasing capillary permeability in the retina
KR20050026002A (ko) *	2002-07-26	2005-03-14	디 인스티튜트스 포 파마슈티컬 디스커버리, 엘엘씨	치환된 인돌알칸산 유도체 및 이를 함유하는 당뇨 합병증치료용 제형
US7572910B2 (en) *	2003-02-20	2009-08-11	Pfizer, Inc.	Pyridazinone aldose reductase inhibitors
US20110092566A1 (en) *	2004-11-19	2011-04-21	Srivastava Satish K	Treatment of cancer with aldose reductase inhibitors
JP4838582B2 (ja) *	2004-12-27	2011-12-14	岐阜プラスチック工業株式会社	台車用本体
ES2371393T3 (es)	2007-03-12	2011-12-30	Zadec Aps	Extracto antidiabético de rooibos.
EP2848252A3 (en)	2007-03-23	2015-06-17	The Board of Regents of the University of Texas System	Aldose reductase inhibitors for use in treating uveitis
US20090270490A1 (en) *	2008-04-24	2009-10-29	The Board Of Regents Of The University Of Texas System	Methods involving aldose reductase inhibition
EP2654749B1 (en)	2010-12-23	2017-05-10	The Board of Regents of The University of Texas System	Methods for treating copd
CA2895162C (en) *	2012-12-14	2021-03-09	D. Lynn Kirkpatrick	Methods and compositions for inhibiting cnksr1
CA2983260C (en)	2015-04-20	2024-01-23	Phusis Therapeutics, Inc.	Sulfonamide compounds, compositions and methods for inhibiting cnksr1
WO2020071386A1 (ja) *	2018-10-04	2020-04-09	日東電工株式会社	耐熱離型シート及び熱圧着方法
JP6751974B1 (ja) *	2019-10-16	2020-09-09	株式会社コバヤシ	離型フィルム及び離型フィルムの製造方法

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Publication number	Priority date	Publication date	Assignee	Title
US3833579A (en) *	1935-11-11	1974-09-03	Inoue Michiro	4-carbamoyl phthalazones
JPS5116430B2 (no) *	1971-08-05	1976-05-24
GB1398549A (en) *	1972-11-06	1975-06-25	Boots Co Ltd	Phthalazine derivatives and their use in pharmaceutical compo sitions
AR205004A1 (es) *	1973-10-30	1976-03-31	Ishikawa M	Procedimiento para preparar derivados de 6,8-dialquil-7-alcoxi-carbonil-4-hidroximetil-1-ftalazona y la 7,8-lactona
DE2451117A1 (de) *	1973-10-31	1975-05-22	Boots Co Ltd	Therapeutisch wirksame verbindungen
IE43079B1 (en) *	1975-03-20	1980-12-17	Ici Ltd	Quinolone derivatives
GB1502312A (en)	1975-03-20	1978-03-01	Ici Ltd	Quinolone derivatives
JPS5214788A (en) *	1975-07-21	1977-02-03	Fuji Photo Film Co Ltd	Process for preparing phthalazinone and its derivatives
NL7702763A (nl) *	1976-03-18	1977-09-20	Takio Shimamoto En Masayuki Is	Werkwijze voor de bereiding van thromboxaan- -antagonisten en van preparaten die deze stof- fen bevatten.
IE47592B1 (en) *	1977-12-29	1984-05-02	Ici Ltd	Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture
US4293553A (en) *	1978-08-11	1981-10-06	Masayuki Ishikawa	1-Phthalazone derivatives, and use thereof

1978
- 1978-11-27 IE IE2337/78A patent/IE47592B1/en not_active IP Right Cessation
- 1978-11-28 NZ NZ189034A patent/NZ189034A/xx unknown
- 1978-11-28 IN IN860/DEL/78A patent/IN150196B/en unknown
- 1978-11-29 AU AU42040/78A patent/AU516264B2/en not_active Expired
- 1978-11-29 US US05/964,725 patent/US4251528A/en not_active Expired - Lifetime
- 1978-11-30 DK DK541878A patent/DK151253C/da not_active IP Right Cessation
- 1978-11-30 IL IL56099A patent/IL56099A0/xx not_active IP Right Cessation
- 1978-12-01 EP EP78300720A patent/EP0002895B1/en not_active Expired
- 1978-12-01 DE DE7878300720T patent/DE2861170D1/de not_active Expired
- 1978-12-01 CY CY1219A patent/CY1219A/xx unknown
- 1978-12-06 PH PH21901A patent/PH15435A/en unknown
- 1978-12-12 GR GR57849A patent/GR65303B/el unknown
- 1978-12-14 FI FI783844A patent/FI64357C/fi not_active IP Right Cessation
- 1978-12-16 PL PL1978222157A patent/PL118443B1/pl unknown
- 1978-12-20 SU SU782698853A patent/SU1087075A3/ru active
- 1978-12-20 PT PT68956A patent/PT68956A/pt not_active IP Right Cessation
- 1978-12-21 JP JP15695378A patent/JPS5495582A/ja active Granted
- 1978-12-21 CA CA318,345A patent/CA1107732A/en not_active Expired
- 1978-12-22 HU HU78IE856A patent/HU182585B/hu not_active IP Right Cessation
- 1978-12-26 BG BG7841857A patent/BG34336A3/xx unknown
- 1978-12-28 ZW ZW249/78A patent/ZW24978A1/xx unknown
- 1978-12-28 CS CS789084A patent/CS241015B2/cs unknown
- 1978-12-28 IT IT52480/78A patent/IT1110885B/it active
- 1978-12-28 NO NO784397A patent/NO154346C/no unknown
- 1978-12-29 ES ES476496A patent/ES476496A1/es not_active Expired
- 1978-12-29 AT AT0937678A patent/AT365581B/de not_active IP Right Cessation
- 1978-12-29 DD DD78210284A patent/DD141021A5/de not_active IP Right Cessation
- 1978-12-29 YU YU3127/78A patent/YU41607B/xx unknown
1980
- 1980-10-06 US US06/194,211 patent/US4393062A/en not_active Expired - Lifetime
1981
- 1981-12-04 SU SU813359216A patent/SU1272984A3/ru active
- 1981-12-04 SU SU813359636A patent/SU1072803A3/ru active
1982
- 1982-10-14 YU YU2320/82A patent/YU42054B/xx unknown
- 1982-10-14 YU YU2321/82A patent/YU42807B/xx unknown
1983
- 1983-11-11 SG SG68683A patent/SG68683G/en unknown
1984
- 1984-03-15 HK HK224/84A patent/HK22484A/xx unknown
1985
- 1985-12-30 MY MY359/85A patent/MY8500359A/xx unknown
1987
- 1987-10-28 JP JP62270508A patent/JPS63119469A/ja active Granted

Also Published As

Publication number	Publication date
YU41607B (en)	1987-12-31
GR65303B (en)	1980-08-01
PH15435A (en)	1983-01-18
PL118443B1 (en)	1981-10-31
SG68683G (en)	1984-08-03
NO154346B (no)	1986-05-26
JPS63119469A (ja)	1988-05-24
AU516264B2 (en)	1981-05-28
US4393062A (en)	1983-07-12
IL56099A0 (en)	1979-01-31
YU232182A (en)	1983-01-21
DK151253C (da)	1988-05-16
DE2861170D1 (en)	1981-12-24
JPS6326110B2 (no)	1988-05-27
DD141021A5 (de)	1980-04-09
YU232082A (en)	1983-01-21
SU1272984A3 (ru)	1986-11-23
HK22484A (en)	1984-03-23
FI64357C (fi)	1983-11-10
US4251528A (en)	1981-02-17
SU1087075A3 (ru)	1984-04-15
ES476496A1 (es)	1979-04-16
EP0002895A1 (en)	1979-07-11
YU42054B (en)	1988-04-30
CS241015B2 (en)	1986-03-13
FI64357B (fi)	1983-07-29
NZ189034A (en)	1981-11-19
JPS5495582A (en)	1979-07-28
IE47592B1 (en)	1984-05-02
CA1107732A (en)	1981-08-25
PT68956A (en)	1979-01-01
SU1072803A3 (ru)	1984-02-07
FI783844A (fi)	1979-06-30
AU4204078A (en)	1979-07-05
IE782337L (en)	1979-06-29
ZW24978A1 (en)	1980-10-22
HU182585B (en)	1984-02-28
MY8500359A (en)	1985-12-31
IN150196B (no)	1982-08-14
EP0002895B1 (en)	1981-10-14
IT7852480A0 (it)	1978-12-28
NO784397L (no)	1979-07-02
ATA937678A (de)	1981-06-15
CY1219A (en)	1984-04-06
DK151253B (da)	1987-11-16
BG34336A3 (en)	1983-08-15
AT365581B (de)	1982-01-25
YU312778A (en)	1983-01-21
IT1110885B (it)	1986-01-06
YU42807B (en)	1988-12-31
DK541878A (da)	1979-06-30
JPH0262532B2 (no)	1990-12-26

Publication	Publication Date	Title
NO154346C (no)	1986-09-03	Analogifremgangsmaate for fremstilling av terapeutisk aktive ftalazin-4-yl-eddiksyrederivater.
NO156611C (no)	1987-10-21	Analogifremgangsmaate for fremstilling av terapeutiske virksomme derivater av hydroksykarbonylfosfonsyre.
NO153177C (no)	1986-01-29	Analogifremgangsmaate for fremstilling av farmakologisk aktive tetrazolylalkoksy-karbostyrilderivater.
NO151966C (no)	1985-07-10	Analogifremgangsmaate for fremstilling av terapeutisk virksomme imidazol-5-eddiksyrederivater
NO145915C (no)	1982-06-23	Analogifremgangsmaate for fremstilling av fysiologisk aktive karboksyalkylacylaminosyrer
NO151321C (no)	1985-03-20	Analogifremgangsmaate for fremstilling av terapeutisk aktive karbostyrilderivater
NO151463C (no)	1985-04-17	Analogifremgangsmaate for fremstilling av terapeutisk aktive kinazolinderivater
NO147450C (no)	1983-04-13	Analogifremgangsmaate for fremstilling av terapeutisk aktive kinazolonderivater
NO153136C (no)	1986-01-22	Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive naftyridinderivater.
NO148813C (no)	1983-12-21	Analogifremgangsmaate for fremstilling av farmakologisk aktive karbostyrilderivater
NO152935C (no)	1985-12-18	Analogifremgangsmaate for fremstilling av anti-inflammatorisk virksomme tioetiansyrederivater.
NO159019C (no)	1988-11-23	Analogifremgangsmaate for fremstilling av farmakologisk aktive 6beta-hydroksyalkylpenicillansyrederivater.
NO154522C (no)	1986-10-08	Analogifremgangsmaate for fremstilling av terapeutisk virksomme kinolinderivater.
NO153569C (no)	1986-05-21	Analogifremgangsmaate for fremstilling av terapeutisk aktive merkaptoacetyl-prolin-derivater.
NO145379C (no)	1982-03-10	Analogifremgangsmaate for fremstilling av terapeutisk aktive n2-arylsulfonyl-l-argininamider.
NO148777C (no)	1984-01-25	Analogifremgangsmaate for fremstilling av terapeutisk aktive antrakinon-derivater
NO146095C (no)	1982-08-11	Analogifremgangsmaate ved fremstilling av terapeutisk aktive kinazolin-derivater
NO152654C (no)	1985-10-30	Analogifremgangsmaate ved fremstilling av nye, terapeutisk aktive derivater av 7-acylamido-3-cephem-4-karboksylsyre
NO802087L (no)	1981-01-14	Analogifremgangsmaate for fremstilling av terapeutisk aktive karboksylsyrederivater
NO151500C (no)	1985-04-24	Analogifremgangsmaate for fremstilling av terapeutisk aktive tiazoloksamsyre-derivater
NO781878L (no)	1978-12-01	Analogifremgangsmaate for fremstilling av terapeutisk aktive pyridobenzodiazepiner.
NO151285C (no)	1985-03-13	Analogifremgangsmaate for fremstilling av terapeutisk aktive di-o-n-alkyl-glycerolderivater
NO148454C (no)	1983-10-12	Analogifremgangsmaate for fremstilling av terapeutisk aktive tiazolidin-dionderivater
NO151660C (no)	1985-05-15	Analogifremgangsmaate til fremstilling av terapeutisk aktive imidazolderivater.
NO780644L (no)	1978-08-25	Fremgangsmaate til fremstilling av terapeutisk virksomme 9-hydroksyetoksymetylguanin-derivater