NL7614052A - Basisch gesubstitueerde indoolderivaten en hun bereiding. - Google Patents
Basisch gesubstitueerde indoolderivaten en hun bereiding.Info
- Publication number
- NL7614052A NL7614052A NL7614052A NL7614052A NL7614052A NL 7614052 A NL7614052 A NL 7614052A NL 7614052 A NL7614052 A NL 7614052A NL 7614052 A NL7614052 A NL 7614052A NL 7614052 A NL7614052 A NL 7614052A
- Authority
- NL
- Netherlands
- Prior art keywords
- preparation
- indole derivatives
- substituted indole
- basically substituted
- basically
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19752557341 DE2557341A1 (de) | 1975-12-19 | 1975-12-19 | Basisch substituierte indolderivate und verfahren zu ihrer herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
NL7614052A true NL7614052A (nl) | 1977-06-21 |
Family
ID=5964904
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL7614052A NL7614052A (nl) | 1975-12-19 | 1976-12-17 | Basisch gesubstitueerde indoolderivaten en hun bereiding. |
Country Status (22)
Country | Link |
---|---|
US (1) | US4148895A (it) |
JP (1) | JPS5277067A (it) |
AT (1) | ATA936176A (it) |
AU (1) | AU2070076A (it) |
BE (1) | BE849627A (it) |
DE (1) | DE2557341A1 (it) |
DK (1) | DK571476A (it) |
EG (1) | EG12485A (it) |
ES (1) | ES454234A1 (it) |
FI (1) | FI763622A (it) |
FR (1) | FR2335215A1 (it) |
GB (1) | GB1573809A (it) |
GR (1) | GR61172B (it) |
IL (1) | IL51119A0 (it) |
IT (1) | IT1065425B (it) |
LU (1) | LU76426A1 (it) |
NL (1) | NL7614052A (it) |
NO (1) | NO764299L (it) |
NZ (1) | NZ182908A (it) |
PT (1) | PT65980B (it) |
SE (1) | SE7614218L (it) |
ZA (1) | ZA767522B (it) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH653021A5 (fr) * | 1981-04-24 | 1985-12-13 | Delalande Sa | Derives piperidino, piperazino et homopiperazino, n-substitues par un groupe heterocyclique aromatique, leur procede de preparation et composition therapeutique les contenant. |
JPS5936675A (ja) * | 1982-07-13 | 1984-02-28 | サンド・アクチエンゲゼルシヤフト | 二環性複素環式カルボン酸アザビシクロアルキルエステルまたはアミド |
US4588740A (en) * | 1982-12-07 | 1986-05-13 | Smithkline Beckman Corporation | Pharmaceutical methods using 4-aminoalkyl-2(3H)-indolones |
FR2557110B1 (fr) * | 1983-12-23 | 1989-11-24 | Sandoz Sa | Nouveaux derives d'amines cycliques, leur preparation et leur utilisation comme medicaments |
FR2578842B1 (fr) * | 1985-03-15 | 1987-04-10 | Rhone Poulenc Sante | Nouveaux derives de la pyrrolo(1,2-a) azepinone, leur preparation et les compositions pharmaceutiques qui les contiennent |
DE3531658A1 (de) * | 1985-09-05 | 1987-03-12 | Boehringer Mannheim Gmbh | Heterocyclisch substituierte indole, zwischenprodukte, verfahren zu ihrer herstellung und arzneimittel |
US5004812A (en) * | 1987-06-26 | 1991-04-02 | E. I. Du Pont De Nemours And Company | Direct positive dimethine cyanine dyes containing 1-aryl-2-heteroaryl indole nucleus |
US5254552A (en) * | 1988-05-24 | 1993-10-19 | American Home Products Corporation | Aryl-and heteroaryl piperazinyl carboxamides having central nervous system activity |
IL98392A (en) * | 1990-06-07 | 1996-01-19 | Wellcome Found | History of indole, their preparation and the pharmaceutical preparations containing them |
US5229517A (en) * | 1990-09-27 | 1993-07-20 | Hoechst-Roussel Pharmaceuticals Incorporated | 2-(4-Piperindinyl)-1H-pyrido[4,3-B]indol-1-ones and related compounds |
US5102889B1 (en) * | 1990-09-27 | 1993-05-11 | 2-(4-piperidinyl)-1h-pyrido(4,3-b)indol-1-ones and related compounds | |
US5284862A (en) * | 1991-03-18 | 1994-02-08 | Warner-Lambert Company | Derivatives of 2-carboxyindoles having pharmaceutical activity |
JP3140155B2 (ja) * | 1992-03-09 | 2001-03-05 | 杏林製薬株式会社 | N,n’−ジ置換アミド誘導体 |
ES2063700B1 (es) * | 1993-04-28 | 1995-07-16 | Vita Invest Sa | Agente activo sobre el sistema nervioso central, proceso para su preparacion y composiciones farmaceuticas que lo contengan. |
US5955492A (en) * | 1996-03-28 | 1999-09-21 | Smithkline Beecham Corporation | Carboxylic acid indole inhibitors of chemokines |
CA2307114A1 (en) * | 1997-10-22 | 1999-04-29 | Clint Duane Walker | Arylpiperazines as serotonin reuptake inhibitors and 5-ht1d.alpha. antagonists |
JP2003040866A (ja) * | 2001-07-31 | 2003-02-13 | Nippon Kayaku Co Ltd | N置換インドール誘導体、その製造法及びそれを有効成分とする害虫防除剤 |
CN1870991A (zh) * | 2003-09-04 | 2006-11-29 | 安万特药物公司 | 作为多聚(adp-核糖)聚合酶(parp)抑制剂的被取代的吲哚类化合物 |
CA2858520A1 (en) * | 2006-05-18 | 2007-11-29 | Pharmacyclics Inc. | Intracellular kinase inhibitors |
EP2155643B1 (en) | 2007-06-08 | 2016-08-10 | MannKind Corporation | Ire-1a inhibitors |
CA2712854C (en) * | 2008-01-31 | 2016-02-23 | Sanofi-Aventis | Cyclic indole-3-carboxamides, their preparation and their use as pharmaceuticals |
CA2787785C (en) * | 2010-01-28 | 2018-03-06 | President And Fellows Of Harvard College | Compositions and methods for enhancing proteasome activity |
EP3552664A1 (en) | 2011-05-12 | 2019-10-16 | Proteostasis Therapeutics, Inc. | Proteostasis regulators |
US9849135B2 (en) | 2013-01-25 | 2017-12-26 | President And Fellows Of Harvard College | USP14 inhibitors for treating or preventing viral infections |
WO2015073528A1 (en) | 2013-11-12 | 2015-05-21 | Proteostasis Therapeutics, Inc. | Proteasome activity enhancing compounds |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3320278A (en) * | 1965-06-30 | 1967-05-16 | Merck & Co Inc | Alpha-(2-amino)-3-indolyl lower aliphatic acid derivatives |
US3847920A (en) * | 1973-05-17 | 1974-11-12 | Warner Lambert Co | 3-substituted pyrimido(4,5-b)indoles |
US3980668A (en) * | 1974-09-18 | 1976-09-14 | Bristol-Myers Company | Anti-arrhythimic 5-endo-(3-indolecarbonyloxy)-N-[amino-(lower)alkyl]bicyclo[2,2,1]heptane-2,3-di-endo-carboxylic acid imides |
-
1975
- 1975-12-19 DE DE19752557341 patent/DE2557341A1/de not_active Withdrawn
-
1976
- 1976-12-14 ES ES454234A patent/ES454234A1/es not_active Expired
- 1976-12-16 US US05/751,084 patent/US4148895A/en not_active Expired - Lifetime
- 1976-12-16 FI FI763622A patent/FI763622A/fi not_active Application Discontinuation
- 1976-12-17 NO NO764299A patent/NO764299L/no unknown
- 1976-12-17 PT PT65980A patent/PT65980B/pt unknown
- 1976-12-17 IL IL51119A patent/IL51119A0/xx unknown
- 1976-12-17 SE SE7614218A patent/SE7614218L/xx unknown
- 1976-12-17 AU AU20700/76A patent/AU2070076A/en not_active Expired
- 1976-12-17 IT IT30581/76A patent/IT1065425B/it active
- 1976-12-17 ZA ZA767522A patent/ZA767522B/xx unknown
- 1976-12-17 NL NL7614052A patent/NL7614052A/xx not_active Application Discontinuation
- 1976-12-17 AT AT936176A patent/ATA936176A/de not_active Application Discontinuation
- 1976-12-17 LU LU76426A patent/LU76426A1/xx unknown
- 1976-12-17 NZ NZ182908A patent/NZ182908A/xx unknown
- 1976-12-17 DK DK571476A patent/DK571476A/da not_active Application Discontinuation
- 1976-12-18 JP JP51151502A patent/JPS5277067A/ja active Pending
- 1976-12-18 EG EG772/76A patent/EG12485A/xx active
- 1976-12-18 GR GR52437A patent/GR61172B/el unknown
- 1976-12-20 GB GB53125/76A patent/GB1573809A/en not_active Expired
- 1976-12-20 BE BE173448A patent/BE849627A/xx unknown
- 1976-12-20 FR FR7638399A patent/FR2335215A1/fr not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
FI763622A (it) | 1977-06-20 |
US4148895A (en) | 1979-04-10 |
IL51119A0 (en) | 1977-02-28 |
IT1065425B (it) | 1985-02-25 |
GB1573809A (en) | 1980-08-28 |
DK571476A (da) | 1977-06-20 |
AU2070076A (en) | 1978-06-22 |
DE2557341A1 (de) | 1977-06-30 |
EG12485A (en) | 1981-06-30 |
NO764299L (it) | 1977-06-21 |
ES454234A1 (es) | 1977-12-16 |
ZA767522B (en) | 1977-11-30 |
LU76426A1 (it) | 1977-07-05 |
NZ182908A (en) | 1979-08-31 |
SE7614218L (sv) | 1977-06-20 |
PT65980B (de) | 1978-07-05 |
PT65980A (de) | 1977-01-01 |
BE849627A (fr) | 1977-06-20 |
FR2335215A1 (fr) | 1977-07-15 |
JPS5277067A (en) | 1977-06-29 |
ATA936176A (de) | 1980-01-15 |
GR61172B (en) | 1978-10-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BV | The patent application has lapsed |