NL7614052A - Basisch gesubstitueerde indoolderivaten en hun bereiding. - Google Patents

Basisch gesubstitueerde indoolderivaten en hun bereiding.

Info

Publication number: NL7614052A
Authority: NL; Netherlands
Prior art keywords: preparation; indole derivatives; substituted indole; basically substituted; basically
Prior art date: 1975-12-19

Application number

NL7614052A

Other languages

English (en)

Dutch (nl)

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-12-19

Filing date

1976-12-17

Publication date

1977-06-21

1976-12-17 Application filed by Hoechst Ag filed Critical Hoechst Ag

1977-06-21 Publication of NL7614052A publication Critical patent/NL7614052A/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NL7614052A 1975-12-19 1976-12-17 Basisch gesubstitueerde indoolderivaten en hun bereiding. NL7614052A (nl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19752557341 DE2557341A1 (de)	1975-12-19	1975-12-19	Basisch substituierte indolderivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number	Publication Date
NL7614052A true NL7614052A (nl)	1977-06-21

Family

ID=5964904

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NL7614052A NL7614052A (nl)	1975-12-19	1976-12-17	Basisch gesubstitueerde indoolderivaten en hun bereiding.

Country Status (22)

Country	Link
US (1)	US4148895A (it)
JP (1)	JPS5277067A (it)
AT (1)	ATA936176A (it)
AU (1)	AU2070076A (it)
BE (1)	BE849627A (it)
DE (1)	DE2557341A1 (it)
DK (1)	DK571476A (it)
EG (1)	EG12485A (it)
ES (1)	ES454234A1 (it)
FI (1)	FI763622A (it)
FR (1)	FR2335215A1 (it)
GB (1)	GB1573809A (it)
GR (1)	GR61172B (it)
IL (1)	IL51119A0 (it)
IT (1)	IT1065425B (it)
LU (1)	LU76426A1 (it)
NL (1)	NL7614052A (it)
NO (1)	NO764299L (it)
NZ (1)	NZ182908A (it)
PT (1)	PT65980B (it)
SE (1)	SE7614218L (it)
ZA (1)	ZA767522B (it)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH653021A5 (fr) *	1981-04-24	1985-12-13	Delalande Sa	Derives piperidino, piperazino et homopiperazino, n-substitues par un groupe heterocyclique aromatique, leur procede de preparation et composition therapeutique les contenant.
JPS5936675A (ja) *	1982-07-13	1984-02-28	サンド・アクチエンゲゼルシヤフト	二環性複素環式カルボン酸アザビシクロアルキルエステルまたはアミド
US4588740A (en) *	1982-12-07	1986-05-13	Smithkline Beckman Corporation	Pharmaceutical methods using 4-aminoalkyl-2(3H)-indolones
FR2557110B1 (fr) *	1983-12-23	1989-11-24	Sandoz Sa	Nouveaux derives d'amines cycliques, leur preparation et leur utilisation comme medicaments
FR2578842B1 (fr) *	1985-03-15	1987-04-10	Rhone Poulenc Sante	Nouveaux derives de la pyrrolo(1,2-a) azepinone, leur preparation et les compositions pharmaceutiques qui les contiennent
DE3531658A1 (de) *	1985-09-05	1987-03-12	Boehringer Mannheim Gmbh	Heterocyclisch substituierte indole, zwischenprodukte, verfahren zu ihrer herstellung und arzneimittel
US5004812A (en) *	1987-06-26	1991-04-02	E. I. Du Pont De Nemours And Company	Direct positive dimethine cyanine dyes containing 1-aryl-2-heteroaryl indole nucleus
US5254552A (en) *	1988-05-24	1993-10-19	American Home Products Corporation	Aryl-and heteroaryl piperazinyl carboxamides having central nervous system activity
IL98392A (en) *	1990-06-07	1996-01-19	Wellcome Found	History of indole, their preparation and the pharmaceutical preparations containing them
US5229517A (en) *	1990-09-27	1993-07-20	Hoechst-Roussel Pharmaceuticals Incorporated	2-(4-Piperindinyl)-1H-pyrido[4,3-B]indol-1-ones and related compounds
US5102889B1 (en) *	1990-09-27	1993-05-11		2-(4-piperidinyl)-1h-pyrido(4,3-b)indol-1-ones and related compounds
US5284862A (en) *	1991-03-18	1994-02-08	Warner-Lambert Company	Derivatives of 2-carboxyindoles having pharmaceutical activity
JP3140155B2 (ja) *	1992-03-09	2001-03-05	杏林製薬株式会社	Ｎ，ｎ’−ジ置換アミド誘導体
ES2063700B1 (es) *	1993-04-28	1995-07-16	Vita Invest Sa	Agente activo sobre el sistema nervioso central, proceso para su preparacion y composiciones farmaceuticas que lo contengan.
US5955492A (en) *	1996-03-28	1999-09-21	Smithkline Beecham Corporation	Carboxylic acid indole inhibitors of chemokines
CA2307114A1 (en) *	1997-10-22	1999-04-29	Clint Duane Walker	Arylpiperazines as serotonin reuptake inhibitors and 5-ht1d.alpha. antagonists
JP2003040866A (ja) *	2001-07-31	2003-02-13	Nippon Kayaku Co Ltd	Ｎ置換インドール誘導体、その製造法及びそれを有効成分とする害虫防除剤
CN1870991A (zh) *	2003-09-04	2006-11-29	安万特药物公司	作为多聚(adp－核糖)聚合酶(parp)抑制剂的被取代的吲哚类化合物
CA2858520A1 (en) *	2006-05-18	2007-11-29	Pharmacyclics Inc.	Intracellular kinase inhibitors
EP2155643B1 (en)	2007-06-08	2016-08-10	MannKind Corporation	Ire-1a inhibitors
CA2712854C (en) *	2008-01-31	2016-02-23	Sanofi-Aventis	Cyclic indole-3-carboxamides, their preparation and their use as pharmaceuticals
CA2787785C (en) *	2010-01-28	2018-03-06	President And Fellows Of Harvard College	Compositions and methods for enhancing proteasome activity
EP3552664A1 (en)	2011-05-12	2019-10-16	Proteostasis Therapeutics, Inc.	Proteostasis regulators
US9849135B2 (en)	2013-01-25	2017-12-26	President And Fellows Of Harvard College	USP14 inhibitors for treating or preventing viral infections
WO2015073528A1 (en)	2013-11-12	2015-05-21	Proteostasis Therapeutics, Inc.	Proteasome activity enhancing compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3320278A (en) *	1965-06-30	1967-05-16	Merck & Co Inc	Alpha-(2-amino)-3-indolyl lower aliphatic acid derivatives
US3847920A (en) *	1973-05-17	1974-11-12	Warner Lambert Co	3-substituted pyrimido(4,5-b)indoles
US3980668A (en) *	1974-09-18	1976-09-14	Bristol-Myers Company	Anti-arrhythimic 5-endo-(3-indolecarbonyloxy)-N-[amino-(lower)alkyl]bicyclo[2,2,1]heptane-2,3-di-endo-carboxylic acid imides

1975
- 1975-12-19 DE DE19752557341 patent/DE2557341A1/de not_active Withdrawn
1976
- 1976-12-14 ES ES454234A patent/ES454234A1/es not_active Expired
- 1976-12-16 US US05/751,084 patent/US4148895A/en not_active Expired - Lifetime
- 1976-12-16 FI FI763622A patent/FI763622A/fi not_active Application Discontinuation
- 1976-12-17 NO NO764299A patent/NO764299L/no unknown
- 1976-12-17 PT PT65980A patent/PT65980B/pt unknown
- 1976-12-17 IL IL51119A patent/IL51119A0/xx unknown
- 1976-12-17 SE SE7614218A patent/SE7614218L/xx unknown
- 1976-12-17 AU AU20700/76A patent/AU2070076A/en not_active Expired
- 1976-12-17 IT IT30581/76A patent/IT1065425B/it active
- 1976-12-17 ZA ZA767522A patent/ZA767522B/xx unknown
- 1976-12-17 NL NL7614052A patent/NL7614052A/xx not_active Application Discontinuation
- 1976-12-17 AT AT936176A patent/ATA936176A/de not_active Application Discontinuation
- 1976-12-17 LU LU76426A patent/LU76426A1/xx unknown
- 1976-12-17 NZ NZ182908A patent/NZ182908A/xx unknown
- 1976-12-17 DK DK571476A patent/DK571476A/da not_active Application Discontinuation
- 1976-12-18 JP JP51151502A patent/JPS5277067A/ja active Pending
- 1976-12-18 EG EG772/76A patent/EG12485A/xx active
- 1976-12-18 GR GR52437A patent/GR61172B/el unknown
- 1976-12-20 GB GB53125/76A patent/GB1573809A/en not_active Expired
- 1976-12-20 BE BE173448A patent/BE849627A/xx unknown
- 1976-12-20 FR FR7638399A patent/FR2335215A1/fr not_active Withdrawn

Also Published As

Publication number	Publication date
FI763622A (it)	1977-06-20
US4148895A (en)	1979-04-10
IL51119A0 (en)	1977-02-28
IT1065425B (it)	1985-02-25
GB1573809A (en)	1980-08-28
DK571476A (da)	1977-06-20
AU2070076A (en)	1978-06-22
DE2557341A1 (de)	1977-06-30
EG12485A (en)	1981-06-30
NO764299L (it)	1977-06-21
ES454234A1 (es)	1977-12-16
ZA767522B (en)	1977-11-30
LU76426A1 (it)	1977-07-05
NZ182908A (en)	1979-08-31
SE7614218L (sv)	1977-06-20
PT65980B (de)	1978-07-05
PT65980A (de)	1977-01-01
BE849627A (fr)	1977-06-20
FR2335215A1 (fr)	1977-07-15
JPS5277067A (en)	1977-06-29
ATA936176A (de)	1980-01-15
GR61172B (en)	1978-10-03

Legal Events

Date	Code	Title	Description
1981-08-03	BV	The patent application has lapsed

Publication	Publication Date	Title
NL7614052A (nl)	1977-06-21	Basisch gesubstitueerde indoolderivaten en hun bereiding.
NL7612286A (nl)	1977-05-10	Piperidinederivaten en werkwijze voor hun be- reiding.
NL7805647A (nl)	1978-11-28	Mevalonolactonderivaten, hun gebruik en bereiding.
DK115376A (da)	1976-09-21	Kinolonderivater
BE844737A (fr)	1977-01-31	Derives benzylideniques
DK422376A (da)	1977-03-20	Pyrimidinderivater
NL7614050A (nl)	1977-06-21	Basisch gesubstitueerde indoolderivaten en hun bereiding.
SE7601274L (sv)	1976-08-16	Isoxazolylbensamid-derivat
NL7802671A (nl)	1978-09-14	Cefemderivaten en hun bereiding.
NL7606655A (nl)	1976-12-21	Imidylbenzeendi- en -tricarbonzuurderivaten.
DK242776A (da)	1976-12-04	Aromastof
NL7601122A (nl)	1976-08-16	Cyclohexaanderivaten.
NL7413536A (nl)	1975-04-22	Basisch gesubstitueerde 1,4-dihydro-2h-iso- chinolinederivaten en hun bereiding.
NL7608206A (nl)	1977-02-01	Thiazolidinederivaten en werkwijze voor hun bereiding.
NL7607993A (nl)	1977-01-19	Ortho-aminobutyrofenonderivaten.
NL7604911A (nl)	1976-11-16	Anthrachinon-bis-amidinen en hun bereiding.
NL7504171A (nl)	1975-10-15	Tetracyclinederivaten en hun bereiding.
SE7613797L (sv)	1977-06-23	Cyproheptadinderivat
NL7611159A (nl)	1977-04-19	Thiazolidinederivaten en werkwijze voor hun bereiding.
NL7611172A (nl)	1977-04-13	Thiazolinylaminopiperidinederivaten.
NL7607495A (nl)	1977-01-14	1-methyl-2-(fenyloxymethyl)-5-nitro-imidazolen en hun bereiding.
NL7607432A (nl)	1977-01-11	Cyclopentanofenanthreen derivaten en werkwijze voor hun bereiding en toepassing.
SE7608519L (sv)	1977-02-07	Morfantridin-derivat
IT1065617B (it)	1985-03-04	Coloranti antrachinonici e loro preparazione
NL7609285A (nl)	1977-03-01	Gesubstitueerde 2.6-diaminoantrachinonen en hun bereiding.