BE849627A - Derives d'indol substitues par des bases, leur preparation de preparation et leurs applications - Google Patents

Derives d'indol substitues par des bases, leur preparation de preparation et leurs applications

Info

Publication number
BE849627A
BE849627A BE173448A BE173448A BE849627A BE 849627 A BE849627 A BE 849627A BE 173448 A BE173448 A BE 173448A BE 173448 A BE173448 A BE 173448A BE 849627 A BE849627 A BE 849627A
Authority
BE
Belgium
Prior art keywords
preparation
bases
applications
derivatives substituted
indol derivatives
Prior art date
Application number
BE173448A
Other languages
English (en)
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE849627A publication Critical patent/BE849627A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
BE173448A 1975-12-19 1976-12-20 Derives d'indol substitues par des bases, leur preparation de preparation et leurs applications BE849627A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752557341 DE2557341A1 (de) 1975-12-19 1975-12-19 Basisch substituierte indolderivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
BE849627A true BE849627A (fr) 1977-06-20

Family

ID=5964904

Family Applications (1)

Application Number Title Priority Date Filing Date
BE173448A BE849627A (fr) 1975-12-19 1976-12-20 Derives d'indol substitues par des bases, leur preparation de preparation et leurs applications

Country Status (22)

Country Link
US (1) US4148895A (it)
JP (1) JPS5277067A (it)
AT (1) ATA936176A (it)
AU (1) AU2070076A (it)
BE (1) BE849627A (it)
DE (1) DE2557341A1 (it)
DK (1) DK571476A (it)
EG (1) EG12485A (it)
ES (1) ES454234A1 (it)
FI (1) FI763622A (it)
FR (1) FR2335215A1 (it)
GB (1) GB1573809A (it)
GR (1) GR61172B (it)
IL (1) IL51119A0 (it)
IT (1) IT1065425B (it)
LU (1) LU76426A1 (it)
NL (1) NL7614052A (it)
NO (1) NO764299L (it)
NZ (1) NZ182908A (it)
PT (1) PT65980B (it)
SE (1) SE7614218L (it)
ZA (1) ZA767522B (it)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5001133A (en) * 1983-12-23 1991-03-19 Sandoz Ltd. Benzoic acid derivatives

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH653021A5 (fr) * 1981-04-24 1985-12-13 Delalande Sa Derives piperidino, piperazino et homopiperazino, n-substitues par un groupe heterocyclique aromatique, leur procede de preparation et composition therapeutique les contenant.
JPS5936675A (ja) * 1982-07-13 1984-02-28 サンド・アクチエンゲゼルシヤフト 二環性複素環式カルボン酸アザビシクロアルキルエステルまたはアミド
US4588740A (en) * 1982-12-07 1986-05-13 Smithkline Beckman Corporation Pharmaceutical methods using 4-aminoalkyl-2(3H)-indolones
FR2578842B1 (fr) * 1985-03-15 1987-04-10 Rhone Poulenc Sante Nouveaux derives de la pyrrolo(1,2-a) azepinone, leur preparation et les compositions pharmaceutiques qui les contiennent
DE3531658A1 (de) * 1985-09-05 1987-03-12 Boehringer Mannheim Gmbh Heterocyclisch substituierte indole, zwischenprodukte, verfahren zu ihrer herstellung und arzneimittel
US5004812A (en) * 1987-06-26 1991-04-02 E. I. Du Pont De Nemours And Company Direct positive dimethine cyanine dyes containing 1-aryl-2-heteroaryl indole nucleus
US5254552A (en) * 1988-05-24 1993-10-19 American Home Products Corporation Aryl-and heteroaryl piperazinyl carboxamides having central nervous system activity
IL98392A (en) * 1990-06-07 1996-01-19 Wellcome Found History of indole, their preparation and the pharmaceutical preparations containing them
US5229517A (en) * 1990-09-27 1993-07-20 Hoechst-Roussel Pharmaceuticals Incorporated 2-(4-Piperindinyl)-1H-pyrido[4,3-B]indol-1-ones and related compounds
US5102889B1 (en) * 1990-09-27 1993-05-11 2-(4-piperidinyl)-1h-pyrido(4,3-b)indol-1-ones and related compounds
US5284862A (en) * 1991-03-18 1994-02-08 Warner-Lambert Company Derivatives of 2-carboxyindoles having pharmaceutical activity
JP3140155B2 (ja) * 1992-03-09 2001-03-05 杏林製薬株式会社 Ｎ，ｎ’−ジ置換アミド誘導体
ES2063700B1 (es) * 1993-04-28 1995-07-16 Vita Invest Sa Agente activo sobre el sistema nervioso central, proceso para su preparacion y composiciones farmaceuticas que lo contengan.
US5955492A (en) * 1996-03-28 1999-09-21 Smithkline Beecham Corporation Carboxylic acid indole inhibitors of chemokines
CA2307114A1 (en) * 1997-10-22 1999-04-29 Clint Duane Walker Arylpiperazines as serotonin reuptake inhibitors and 5-ht1d.alpha. antagonists
JP2003040866A (ja) * 2001-07-31 2003-02-13 Nippon Kayaku Co Ltd Ｎ置換インドール誘導体、その製造法及びそれを有効成分とする害虫防除剤
CN1870991A (zh) * 2003-09-04 2006-11-29 安万特药物公司 作为多聚(adp－核糖)聚合酶(parp)抑制剂的被取代的吲哚类化合物
CA2858520A1 (en) * 2006-05-18 2007-11-29 Pharmacyclics Inc. Intracellular kinase inhibitors
EP2155643B1 (en) 2007-06-08 2016-08-10 MannKind Corporation Ire-1a inhibitors
CA2712854C (en) * 2008-01-31 2016-02-23 Sanofi-Aventis Cyclic indole-3-carboxamides, their preparation and their use as pharmaceuticals
CA2787785C (en) * 2010-01-28 2018-03-06 President And Fellows Of Harvard College Compositions and methods for enhancing proteasome activity
EP3552664A1 (en) 2011-05-12 2019-10-16 Proteostasis Therapeutics, Inc. Proteostasis regulators
US9849135B2 (en) 2013-01-25 2017-12-26 President And Fellows Of Harvard College USP14 inhibitors for treating or preventing viral infections
WO2015073528A1 (en) 2013-11-12 2015-05-21 Proteostasis Therapeutics, Inc. Proteasome activity enhancing compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3320278A (en) * 1965-06-30 1967-05-16 Merck & Co Inc Alpha-(2-amino)-3-indolyl lower aliphatic acid derivatives
US3847920A (en) * 1973-05-17 1974-11-12 Warner Lambert Co 3-substituted pyrimido(4,5-b)indoles
US3980668A (en) * 1974-09-18 1976-09-14 Bristol-Myers Company Anti-arrhythimic 5-endo-(3-indolecarbonyloxy)-N-[amino-(lower)alkyl]bicyclo[2,2,1]heptane-2,3-di-endo-carboxylic acid imides

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5001133A (en) * 1983-12-23 1991-03-19 Sandoz Ltd. Benzoic acid derivatives

Also Published As

Publication number Publication date
FI763622A (it) 1977-06-20
US4148895A (en) 1979-04-10
IL51119A0 (en) 1977-02-28
IT1065425B (it) 1985-02-25
GB1573809A (en) 1980-08-28
DK571476A (da) 1977-06-20
AU2070076A (en) 1978-06-22
NL7614052A (nl) 1977-06-21
DE2557341A1 (de) 1977-06-30
EG12485A (en) 1981-06-30
NO764299L (it) 1977-06-21
ES454234A1 (es) 1977-12-16
ZA767522B (en) 1977-11-30
LU76426A1 (it) 1977-07-05
NZ182908A (en) 1979-08-31
SE7614218L (sv) 1977-06-20
PT65980B (de) 1978-07-05
PT65980A (de) 1977-01-01
FR2335215A1 (fr) 1977-07-15
JPS5277067A (en) 1977-06-29
ATA936176A (de) 1980-01-15
GR61172B (en) 1978-10-03

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