NL7608411A - Werkwijze voor het bereiden van acylderivaten van macrolide antibiotica, werkwijze voor het bereiden van een geneesmiddel en zo gevormd geneesmiddel. - Google Patents

Werkwijze voor het bereiden van acylderivaten van macrolide antibiotica, werkwijze voor het bereiden van een geneesmiddel en zo gevormd geneesmiddel.

Info

Publication number: NL7608411A
Authority: NL; Netherlands
Prior art keywords: preparing; medicinal product; macrolide antibiotics; acyl derivatives; positions
Prior art date: 1975-08-01

Application number

NL7608411A

Other languages

English (en)

Other versions

NL176087C (nl

Original Assignee

Sanraku Ocean Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-08-01

Filing date

1976-07-29

Publication date

1977-02-03

1975-08-01 Priority claimed from JP9305375A external-priority patent/JPS5218889A/ja

1975-09-12 Priority claimed from JP50110010A external-priority patent/JPS5234983A/ja

1975-12-27 Priority claimed from JP15838875A external-priority patent/JPS5282790A/ja

1976-05-15 Priority claimed from JP5562676A external-priority patent/JPS52139088A/ja

1976-07-29 Application filed by Sanraku Ocean Co filed Critical Sanraku Ocean Co

1977-02-03 Publication of NL7608411A publication Critical patent/NL7608411A/nl

1985-02-18 Application granted granted Critical

1985-02-18 Publication of NL176087C publication Critical patent/NL176087C/nl

Links

239000003120 macrolide antibiotic agent Substances 0.000 title abstract 3
229940126601 medicinal product Drugs 0.000 title 2
244000005700 microbiome Species 0.000 abstract 2
WBPYTXDJUQJLPQ-VMXQISHHSA-N tylosin Chemical class O([C@@H]1[C@@H](C)O[C@H]([C@@H]([C@H]1N(C)C)O)O[C@@H]1[C@@H](C)[C@H](O)CC(=O)O[C@@H]([C@H](/C=C(\C)/C=C/C(=O)[C@H](C)C[C@@H]1CC=O)CO[C@H]1[C@@H]([C@H](OC)[C@H](O)[C@@H](C)O1)OC)CC)[C@H]1C[C@@](C)(O)[C@@H](O)[C@H](C)O1 WBPYTXDJUQJLPQ-VMXQISHHSA-N 0.000 abstract 2
ODIGIKRIUKFKHP-UHFFFAOYSA-N (n-propan-2-yloxycarbonylanilino) acetate Chemical compound CC(C)OC(=O)N(OC(C)=O)C1=CC=CC=C1 ODIGIKRIUKFKHP-UHFFFAOYSA-N 0.000 abstract 1
241000187747 Streptomyces Species 0.000 abstract 1
229930194936 Tylosin Natural products 0.000 abstract 1
239000004182 Tylosin Substances 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
230000001580 bacterial effect Effects 0.000 abstract 1
238000005842 biochemical reaction Methods 0.000 abstract 1
230000036765 blood level Effects 0.000 abstract 1
238000007796 conventional method Methods 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229960004059 tylosin Drugs 0.000 abstract 1
235000019375 tylosin Nutrition 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

NLAANVRAGE7608411,A 1975-08-01 1976-07-29 Werkwijze voor de bereiding van 16-ring macroliden en voor de bereiding van een geneesmiddel. NL176087C (nl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
JP9305375A JPS5218889A (en)	1975-08-01	1975-08-01	Biochemical acetylation of macrolide antibiotics
JP50110010A JPS5234983A (en)	1975-09-12	1975-09-12	Biochemical acylation of macrolide antibiotics
JP15838875A JPS5282790A (en)	1975-12-27	1975-12-27	Preparation of macroride antibiotics
JP5562676A JPS52139088A (en)	1976-05-15	1976-05-15	Antibiotics tyrocin derivatives and their preparation

Publications (2)

Publication Number	Publication Date
NL7608411A true NL7608411A (nl)	1977-02-03
NL176087C NL176087C (nl)	1985-02-18

Family

ID=27463226

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NLAANVRAGE7608411,A NL176087C (nl)	1975-08-01	1976-07-29	Werkwijze voor de bereiding van 16-ring macroliden en voor de bereiding van een geneesmiddel.

Country Status (11)

Country	Link
US (1)	US4092473A (nl)
BR (1)	BR7605024A (nl)
CA (1)	CA1063954A (nl)
CH (1)	CH619267A5 (nl)
DE (1)	DE2634499C2 (nl)
DK (1)	DK151262C (nl)
ES (1)	ES450333A1 (nl)
FR (1)	FR2319374A1 (nl)
GB (1)	GB1539907A (nl)
NL (1)	NL176087C (nl)
SE (1)	SE441598B (nl)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0001841A2 (en) *	1977-11-08	1979-05-16	Sanraku-Ocean Co., Ltd.	Tylosin derivatives
EP0121328A2 (en) *	1983-03-03	1984-10-10	Eli Lilly And Company	Macrolide derivatives

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE445739B (sv) *	1978-09-14	1986-07-14	Toyo Jozo Kk	3", 4"-diacyltylosinderivat
US4349665A (en) *	1980-06-27	1982-09-14	Schering Corporation	Macrolide antibiotic complex
US4362881A (en) *	1980-07-02	1982-12-07	Eli Lilly And Company	Tylactone
US4299953A (en) *	1980-07-29	1981-11-10	Eli Lilly And Company	Mycarosyltylactone
US4357325A (en) *	1981-04-20	1982-11-02	Eli Lilly And Company	Methods of controlling Pasteurella infections
US4487923A (en) *	1981-12-14	1984-12-11	Eli Lilly And Company	Method of preparing 23-monoesters of OMT and DMT
US4401660A (en) *	1981-12-14	1983-08-30	Eli Lilly And Company	Ester derivatives of 5-O-mycaminosyl tylonolide and method of using same
US4396613A (en) *	1981-12-14	1983-08-02	Eli Lilly And Company	23-Ester derivatives of DMT and method of using same
US4436733A (en)	1982-03-03	1984-03-13	Eli Lilly And Company	4"- And 3-ester derivatives of DMT and DMOT
US4597969A (en) *	1982-04-05	1986-07-01	Merck Sharp & Dohme	Stabilization of unstable drugs or food supplements
US4412359A (en) *	1982-04-26	1983-11-01	Myers William D	Posterior chamber lens implant
US4522919A (en) *	1983-03-03	1985-06-11	Eli Lilly And Company	Method of producing antibacterial agents and bioconverting microorganism therefor
US4594337A (en) *	1983-03-03	1986-06-10	Eli Lilly And Company	Methods of controlling mycoplasma infections
US4559301A (en) *	1983-03-03	1985-12-17	Eli Lilly And Company	Process for preparing macrocin derivatives
US4656258A (en) *	1983-03-03	1987-04-07	Eli Lilly And Company	Macrocin derivatives
JP3074039B2 (ja) *	1991-08-07	2000-08-07	明治製菓株式会社	１６員環マクロライド抗生物質の３位脱アシル体の製造法及びこれに用いる微生物並びに新規マクロライド抗生物質
GB0025556D0 (en) *	2000-10-18	2000-12-06	Eco Animal Health Ltd	Treatment and prophylaxis of disease and infections of pigs and poultry
GB0315629D0 (en) *	2003-07-03	2003-08-13	Eco Animal Health Ltd	New uses for antibiotic
DE602007006663D1 (de)	2006-06-12	2010-07-01	Univ Ramot	Verfahren zur behandlung von krebs
CA2657275C (en)	2006-07-13	2013-09-24	Eco Animal Health Limited	Use of tylvalosin as antiviral agent
CN102659882B (zh) *	2012-05-11	2015-04-22	湖北泱盛生物科技有限公司	一种酒石酸乙酰异戊酰泰乐菌素的提取方法
CN104693255B (zh) *	2015-01-14	2017-05-24	宁夏泰瑞制药股份有限公司	从酒石酸乙酰异戊酰泰乐菌素结晶母液中回收酒石酸乙酰异戊酰泰乐碱的方法
CN104961784A (zh) *	2015-06-11	2015-10-07	宁夏泰瑞制药股份有限公司	一种从酒石酸乙酰异戊酰泰乐菌素结晶母液中回收乙酰异戊酰泰乐碱的方法
CN108358979B (zh) *	2018-05-22	2020-08-25	中牧实业股份有限公司	泰万菌素的纯化方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1278441B (de) *	1958-10-29	1968-09-26	Lilly Co Eli	Verfahren zur Herstellung von Acylderivaten von Tylosin und Desmycosin und deren Salzen
NO116467B (nl) *	1965-03-02	1969-03-31	Rhone Poulenc Sa
FI56187C (fi) *	1970-07-02	1979-12-10	Takeda Chemical Industries Ltd	Foerfarande foer framstaellning av antibiotiskt aktiva estrar av makrolidglykosiderna b-5050 eller tetrahydro b-5050

1976
- 1976-07-23 US US05/708,151 patent/US4092473A/en not_active Expired - Lifetime
- 1976-07-23 CH CH946076A patent/CH619267A5/fr not_active IP Right Cessation
- 1976-07-26 GB GB31117/76A patent/GB1539907A/en not_active Expired
- 1976-07-26 SE SE7608448A patent/SE441598B/xx not_active IP Right Cessation
- 1976-07-29 NL NLAANVRAGE7608411,A patent/NL176087C/nl not_active IP Right Cessation
- 1976-07-29 FR FR7623268A patent/FR2319374A1/fr active Granted
- 1976-07-30 CA CA258,132A patent/CA1063954A/en not_active Expired
- 1976-07-30 BR BR7605024A patent/BR7605024A/pt unknown
- 1976-07-30 ES ES450333A patent/ES450333A1/es not_active Expired
- 1976-07-30 DK DK344976A patent/DK151262C/da not_active IP Right Cessation
- 1976-07-31 DE DE2634499A patent/DE2634499C2/de not_active Expired

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0001841A2 (en) *	1977-11-08	1979-05-16	Sanraku-Ocean Co., Ltd.	Tylosin derivatives
EP0001841A3 (en) *	1977-11-08	1979-05-30	Sanraku-Ocean Co., Ltd.	Tylosin derivatives
EP0121328A2 (en) *	1983-03-03	1984-10-10	Eli Lilly And Company	Macrolide derivatives
EP0121328A3 (en) *	1983-03-03	1985-01-09	Eli Lilly And Company	Macrolide derivatives

Also Published As

Publication number	Publication date
CA1063954A (en)	1979-10-09
DE2634499A1 (de)	1977-03-10
US4092473A (en)	1978-05-30
DE2634499C2 (de)	1982-05-19
SE441598B (sv)	1985-10-21
DK151262B (da)	1987-11-16
SE7608448L (sv)	1977-02-02
DK151262C (da)	1988-05-02
ES450333A1 (es)	1977-11-16
DK344976A (da)	1977-02-02
CH619267A5 (nl)	1980-09-15
GB1539907A (en)	1979-02-07
FR2319374B1 (nl)	1978-11-17
BR7605024A (pt)	1977-08-09
NL176087C (nl)	1985-02-18
FR2319374A1 (fr)	1977-02-25

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Legal Events

Date	Code	Title	Description
1985-01-01	A85	Still pending on 85-01-01
1986-06-16	TNT	Modifications of names of proprietors of patents or applicants of examined patent applications	Owner name: SANRAKU INCORPORATED
1991-05-16	TNT	Modifications of names of proprietors of patents or applicants of examined patent applications	Owner name: MERCIAN CORPORATION
1996-10-01	V4	Discontinued because of reaching the maximum lifetime of a patent	Free format text: 960729