NL7601632A - Antibacterial 1,8-naphthyridine derivs - viz. 7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acids, by ylid hydrolysis - Google Patents

Antibacterial 1,8-naphthyridine derivs - viz. 7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acids, by ylid hydrolysis

Info

Publication number
NL7601632A
NL7601632A NL7601632A NL7601632A NL7601632A NL 7601632 A NL7601632 A NL 7601632A NL 7601632 A NL7601632 A NL 7601632A NL 7601632 A NL7601632 A NL 7601632A NL 7601632 A NL7601632 A NL 7601632A
Authority
NL
Netherlands
Prior art keywords
naphthyridine
hydrolysis
derivs
antibacterial
ylid
Prior art date
Application number
NL7601632A
Other languages
Dutch (nl)
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of NL7601632A publication Critical patent/NL7601632A/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

derivs. of formula (I): (where R is H or 1-10C alkyl) are prepd. by hydrolysis of a cpd. of formula (II): (where R1 is H, 1-4C alkyl, phenyl or 7-15C aralkyl; Y is trialkylamino or an opt. substd. heterocyclic ring with a tert. N atom via which it is bonded to the CR1 gp.). Cpds. (I) are antibacterial agents, e.g. (I; R=H) is used in the treatment of urinary tract infections. The process gives high yields (e.g. 76-93%) of cpds. (I) in pure form.
NL7601632A 1975-02-18 1976-02-18 Antibacterial 1,8-naphthyridine derivs - viz. 7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acids, by ylid hydrolysis NL7601632A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU75CI1546A HU173573B (en) 1975-02-18 1975-02-18 Process for producing new 1,8-naphtridine derivatives

Publications (1)

Publication Number Publication Date
NL7601632A true NL7601632A (en) 1976-08-20

Family

ID=10994553

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7601632A NL7601632A (en) 1975-02-18 1976-02-18 Antibacterial 1,8-naphthyridine derivs - viz. 7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acids, by ylid hydrolysis

Country Status (6)

Country Link
JP (1) JPS51108095A (en)
DK (1) DK63576A (en)
FI (1) FI760388A (en)
HU (1) HU173573B (en)
NL (1) NL7601632A (en)
SE (1) SE7601884L (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4341784A (en) * 1979-09-28 1982-07-27 Dainippon Pharmaceutical Co., Ltd. Naphthyridine derivatives

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3280475A (en) * 1960-04-28 1966-10-25 Leland H Satre Apparatus for pre-drying matrices
US3186108A (en) * 1960-09-22 1965-06-01 George M Clark Suction-type matrix drier with means for controlling drying time and suction

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4341784A (en) * 1979-09-28 1982-07-27 Dainippon Pharmaceutical Co., Ltd. Naphthyridine derivatives

Also Published As

Publication number Publication date
SE7601884L (en) 1976-08-19
DK63576A (en) 1976-08-19
JPS51108095A (en) 1976-09-25
HU173573B (en) 1979-06-28
FI760388A (en) 1976-08-19

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