NL188266C - Werkwijze ter bereiding van een oogheelkundig inplantaat. - Google Patents

Werkwijze ter bereiding van een oogheelkundig inplantaat.

Info

Publication number
NL188266C
NL188266C NLAANVRAGE7607704,A NL7607704A NL188266C NL 188266 C NL188266 C NL 188266C NL 7607704 A NL7607704 A NL 7607704A NL 188266 C NL188266 C NL 188266C
Authority
NL
Netherlands
Prior art keywords
preparation
organic implant
implant
organic
Prior art date
Application number
NLAANVRAGE7607704,A
Other languages
English (en)
Other versions
NL7607704A (nl
NL188266B (nl
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of NL7607704A publication Critical patent/NL7607704A/nl
Publication of NL188266B publication Critical patent/NL188266B/nl
Application granted granted Critical
Publication of NL188266C publication Critical patent/NL188266C/nl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/765Polymers containing oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • A61K31/787Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A61K31/79Polymers of vinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • A61K9/0051Ocular inserts, ocular implants
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
NLAANVRAGE7607704,A 1975-07-29 1976-07-12 Werkwijze ter bereiding van een oogheelkundig inplantaat. NL188266C (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60016875A 1975-07-29 1975-07-29

Publications (3)

Publication Number Publication Date
NL7607704A NL7607704A (nl) 1977-02-01
NL188266B NL188266B (nl) 1991-12-16
NL188266C true NL188266C (nl) 1992-05-18

Family

ID=24402570

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7607704,A NL188266C (nl) 1975-07-29 1976-07-12 Werkwijze ter bereiding van een oogheelkundig inplantaat.

Country Status (16)

Country Link
US (1) US4343787A (nl)
JP (1) JPS5215811A (nl)
AU (1) AU509140B2 (nl)
BE (1) BE844544A (nl)
BR (1) BR7604876A (nl)
CH (1) CH631891A5 (nl)
CY (1) CY1137A (nl)
DE (1) DE2633988C2 (nl)
ES (3) ES450002A1 (nl)
FR (1) FR2319375A1 (nl)
GB (1) GB1543189A (nl)
HK (1) HK282A (nl)
IT (1) IT1062653B (nl)
NL (1) NL188266C (nl)
PT (1) PT65389B (nl)
SE (1) SE431508B (nl)

Families Citing this family (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54145207A (en) * 1978-04-30 1979-11-13 Agency Of Ind Science & Technol High viscosity eye lotion
US4436730A (en) 1979-06-25 1984-03-13 Polymer Technology Corporation Ionic opthalmic cellulose polymer solutions
US4730013A (en) * 1981-10-08 1988-03-08 Merck & Co., Inc. Biosoluble ocular insert
FI831399L (fi) * 1982-04-29 1983-10-30 Agripat Sa Kontaktlins av haerdad polyvinylalkohol
EP0108661A1 (en) * 1982-10-04 1984-05-16 Merck & Co. Inc. Stabilized hydroxypropyl cellulose ophthalmic inserts and process to sterilize the same
US4565198A (en) * 1983-12-27 1986-01-21 Barnes-Hind, Inc. Method for altering the curvature of the cornea
US4660546A (en) * 1984-11-07 1987-04-28 Robert S. Herrick Method for treating for deficiency of tears
US5209927A (en) * 1985-01-23 1993-05-11 Alcon Laboratories, Inc. Ophthalmic solution
US4826871A (en) * 1985-03-13 1989-05-02 Gressel Philip D Topical ophthalmic compositions containing one or more retinoids
FR2588189B1 (fr) * 1985-10-03 1988-12-02 Merck Sharp & Dohme Composition pharmaceutique de type a transition de phase liquide-gel
US4744980A (en) * 1986-04-28 1988-05-17 Holly Frank J Ophthalmic solution for treatment of dry eye syndrome
US4883658A (en) * 1986-04-28 1989-11-28 Holly Frank J Ophthalmic solution for treatment of dry-eye syndrome
US5229128A (en) * 1986-06-11 1993-07-20 Haddad Heskel M Drug delivery ophthalmic insert and method of preparing same
US5322691A (en) * 1986-10-02 1994-06-21 Sohrab Darougar Ocular insert with anchoring protrusions
US5989579A (en) * 1986-10-02 1999-11-23 Escalon Medical Corp. Ocular insert with anchoring protrusions
GB8623661D0 (en) * 1986-10-02 1986-11-05 Darougar S Ocular insert
US4966773A (en) * 1986-11-25 1990-10-30 Alcon Laboratories, Inc. Topical ophthalmic compositions containing microfine retinoid particles
CA1317226C (en) * 1987-05-04 1993-05-04 Phillip E. Pennell Viscoelastic fluid for ophthalmic surgery and method of using same
US5075104A (en) * 1989-03-31 1991-12-24 Alcon Laboratories, Inc. Ophthalmic carboxy vinyl polymer gel for dry eye syndrome
GB8917216D0 (en) * 1989-07-27 1989-09-13 Smith & Nephew Ophthalmic composition
FR2688694B1 (fr) * 1992-03-20 1999-06-25 Vetoquinol Sa Insert ophtalmique bioadhesif.
MY113268A (en) * 1992-12-29 2002-01-31 Insite Vision Incorporated Plasticized bioerodible controlled delivery system
EP0732913B1 (en) 1993-04-30 2003-02-26 Nestle S.A. SYNTHETIC VISCOELASTIC MATERIAL for physiological applications such as FOR OPHTHALMIC APPLICATIONs
US5631004A (en) 1993-09-30 1997-05-20 Alcon Laboratories, Inc. Use of sustained release antibiotic compositions in ophthalmic surgical procedures
TW274516B (nl) * 1993-11-12 1996-04-21 Ciba Geigy Ag
US5773021A (en) * 1994-03-14 1998-06-30 Vetoquinol S.A. Bioadhesive ophthalmic insert
US5466233A (en) * 1994-04-25 1995-11-14 Escalon Ophthalmics, Inc. Tack for intraocular drug delivery and method for inserting and removing same
US5472436A (en) * 1994-07-26 1995-12-05 Fremstad; Daria A. Ocular appliance for delivering medication
US5516808A (en) * 1994-10-27 1996-05-14 Sawaya; Assad S. Topical cellulose pharmaceutical formulation
US5518732A (en) * 1995-02-14 1996-05-21 Chiron Vision, Inc. Bio-erodible ophthalmic shield
DE19508029C2 (de) * 1995-03-07 1997-10-09 Richard Prof Dr Sueverkruep Darreichungsform zur äußerlichen Applikation von ophthalmischen Arzneistoffen und Verfahren zur Herstellung derselben
US6299895B1 (en) 1997-03-24 2001-10-09 Neurotech S.A. Device and method for treating ophthalmic diseases
US5888493A (en) * 1996-12-05 1999-03-30 Sawaya; Assad S. Ophthalmic aqueous gel formulation and related methods
US6193991B1 (en) * 1997-10-29 2001-02-27 Atul J. Shukla Biodegradable delivery systems of biologically active substances
US6281192B1 (en) 1999-03-01 2001-08-28 Vista Scientific Llc Mucin containing ophthalmic preparations
US6264971B1 (en) * 1999-11-04 2001-07-24 Btg International Limited Ocular insert
US6613355B2 (en) 2000-05-11 2003-09-02 A.P. Pharma, Inc. Semi-solid delivery vehicle and pharmaceutical compositions
US20050042194A1 (en) 2000-05-11 2005-02-24 A.P. Pharma, Inc. Semi-solid delivery vehicle and pharmaceutical compositions
EP1299048A4 (en) * 2000-06-28 2005-09-28 Atul J Shukla BIODEGRADABLE VEHICLES AND SYSTEMS FOR DELIVERY OF BIOLOGICALLY ACTIVE SUBSTANCES
US7404825B2 (en) * 2001-06-11 2008-07-29 Herrick Ii Robert S Implant capable of forming a differential image in an eye
EP1404297B1 (en) 2001-06-12 2011-04-27 The Johns Hopkins University School Of Medicine Reservoir device for intraocular drug delivery
FR2833493B1 (fr) * 2001-12-18 2005-09-23 Ioltechnologie Production Forme galenique solide et soluble pour l'administration occulaire de principes actifs et procede de fabrication d'un insert ophtalmique solide et soluble
CA2484512C (en) * 2002-05-17 2013-04-16 Othera Pharmaceuticals, Inc. Treatment of cataracts and other ophthalmic diseases
US7795203B2 (en) * 2002-09-30 2010-09-14 Babizhayev Mark A Method for topical treatment of eye disease and composition and device for said treatment
DE10246900A1 (de) 2002-10-08 2004-04-22 Horstmann, Michael, Dr. Am Auge applizierbare Vorrichtung zur sicheren Dosierung systemischer und tropischer Medikation
US7825134B2 (en) * 2003-05-19 2010-11-02 Othera Holding, Inc. Amelioration of cataracts, macular degeneration and other ophthalmic diseases
TWI336257B (en) * 2003-06-13 2011-01-21 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
US7914803B2 (en) 2003-06-13 2011-03-29 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of three polymers
AU2004249137B2 (en) * 2003-06-13 2010-03-11 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers
US7947295B2 (en) * 2003-06-13 2011-05-24 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers
TWI347847B (en) * 2003-08-20 2011-09-01 Santen Pharmaceutical Co Ltd Drug delivery system for sub-tenon administration of fine particles
EP1658109B1 (en) * 2003-08-26 2014-01-22 Vista Scientific LLC Ocular drug delivery device
US20060020253A1 (en) * 2004-07-26 2006-01-26 Prescott Anthony D Implantable device having reservoir with controlled release of medication and method of manufacturing the same
US7117870B2 (en) * 2004-07-26 2006-10-10 Clarity Corporation Lacrimal insert having reservoir with controlled release of medication and method of manufacturing the same
US20060067978A1 (en) * 2004-09-29 2006-03-30 Bausch & Lomb Incorporated Process for preparing poly(vinyl alcohol) drug delivery devices
US20060068012A1 (en) * 2004-09-29 2006-03-30 Bausch & Lomb Incorporated Process for preparing poly (vinyl alcohol) drug delivery devices with humidity control
WO2007013590A1 (ja) * 2005-07-29 2007-02-01 Santen Pharmaceutical Co., Ltd. 固形組成物を用いた後眼部組織への非侵襲性ドラッグデリバリーシステム
US20070264339A1 (en) * 2006-05-12 2007-11-15 Ap Pharma, Inc. Base-stabilized polyorthoester formulations
US20070265329A1 (en) * 2006-05-12 2007-11-15 Devang Shah T Methods for the prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV)
US20070264338A1 (en) * 2006-05-12 2007-11-15 Shah Devang T Base-stabilized polyorthoester formulations
EP2109442B1 (en) * 2007-02-09 2014-03-26 Novartis AG Ophthalmic compositions containing a synergistic combination of three polymers
CN105998028A (zh) 2007-02-22 2016-10-12 科尔比制药公司 羟胺化合物及其用法
WO2010068827A1 (en) * 2008-12-11 2010-06-17 A.P. Pharma, Inc. Methods for enhancing stability of polyorthoesters and their formulations
WO2010088548A1 (en) 2009-01-29 2010-08-05 Forsight Labs, Llc Posterior segment drug delivery
US8623395B2 (en) 2010-01-29 2014-01-07 Forsight Vision4, Inc. Implantable therapeutic device
US20100226962A1 (en) * 2009-03-03 2010-09-09 Rodstrom Theron R Peri-corneal drug delivery device
CN102596097B (zh) 2009-06-03 2015-05-20 弗赛特实验室有限责任公司 一种眼***件
CA2776748A1 (en) * 2009-10-08 2011-04-14 Neurotech Usa, Inc. Use of pedf in an encapsulated cell-based delivery system
WO2011094170A1 (en) * 2010-01-27 2011-08-04 Alcon Research, Ltd. Pulsatile peri-corneal drug delivery device
US8993626B2 (en) 2010-06-25 2015-03-31 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of treatment using sterculic acid
ES2701405T3 (es) 2010-07-29 2019-02-22 Eleven Biotherapeutics Inc Agonistas y antagonistas del receptor tipo I de IL-1 quimérico
EP3861969A1 (en) 2010-08-05 2021-08-11 ForSight Vision4, Inc. Injector apparatus for drug delivery
WO2012019139A1 (en) 2010-08-05 2012-02-09 Forsight Vision4, Inc. Combined drug delivery methods and apparatus
SI2600812T1 (sl) 2010-08-05 2021-12-31 ForSight Vision4, Inc., Naprava za zdravljenje očesa
US20140031769A1 (en) 2010-11-19 2014-01-30 Forsight Vision4, Inc. Therapeutic agent formulations for implanted devices
EP4249059A3 (en) 2011-06-28 2023-11-29 ForSight Vision4, Inc. An apparatus for collecting a sample of fluid from a reservoir chamber of a therapeutic device for the eye
EP2739252A4 (en) 2011-08-05 2015-08-12 Forsight Vision4 Inc SMALL MOLECULE ADMINISTRATION USING AN IMPLANTABLE THERAPEUTIC DEVICE
WO2013040238A2 (en) 2011-09-13 2013-03-21 Vista Scientific Llc Sustained release ocular drug delivery devices and methods of manufacture
KR102071083B1 (ko) 2011-09-14 2020-01-29 포사이트 비젼5, 인크. 안내 삽입물 장치 및 방법
LT2755600T (lt) 2011-09-16 2021-04-26 Forsight Vision4, Inc. Skysčio pakeitimo aparatas
CA2888808C (en) 2012-10-26 2021-11-09 Forsight Vision5, Inc. Ophthalmic system for sustained release of drug to eye
CN107693781B (zh) 2013-03-13 2021-11-09 巴扎德制药公司 用于眼部递送的嵌合细胞因子制剂
EP2968113B8 (en) 2013-03-14 2020-10-28 Forsight Vision4, Inc. Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant
CA2907681C (en) 2013-03-28 2022-11-22 Forsight Vision4, Inc. Ophthalmic implant for delivering therapeutic substances
EP3177289A4 (en) 2014-08-08 2018-03-21 Forsight Vision4, Inc. Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof
AU2015346450B2 (en) 2014-11-10 2020-01-30 Forsight Vision4, Inc. Expandable drug delivery devices and method of use
EP3283004A4 (en) 2015-04-13 2018-12-05 Forsight Vision5, Inc. Ocular insert composition of semi-crystalline or crystalline pharmaceutically active agent
US10010502B2 (en) 2015-05-19 2018-07-03 Amorphex Therapeutics Llc Device that delivers a sustained low-dose of a myopia-suppressing drug, while preserving pupillary function and accommodation
EP3377009B1 (en) 2015-11-20 2020-10-28 ForSight Vision4, Inc. Porous structures for extended release drug delivery devices
EP3439591B1 (en) 2016-04-05 2020-09-23 ForSight Vision4, Inc. Implantable ocular drug delivery devices
KR20200093581A (ko) 2017-11-21 2020-08-05 포사이트 비젼4, 인크. 확장 가능한 포트 전달 시스템을 위한 유체 교환 기기 및 사용 방법
WO2023214027A1 (en) 2022-05-06 2023-11-09 Eyed Pharma Insert for the treatment of dry eyes
BE1030504B1 (fr) 2022-05-06 2023-12-04 Eyed Pharma Insert composite pour le traitement de la sécheresse oculaire
BE1030503B1 (fr) 2022-05-06 2023-12-04 Eyed Pharma Insert pour le traitement de la sécheresse oculaire

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3856919A (en) * 1970-06-08 1974-12-24 Burton Parsons Chemicals Inc Ophthalmic solution
US3767788A (en) * 1970-06-08 1973-10-23 Burton Parsons Chemicals Inc Ophthalmic solution
SE352811B (nl) * 1971-06-04 1973-01-15 Pharmacia Ab
US3845201A (en) * 1972-04-24 1974-10-29 S Loucas Solid state ophthalmic medication delivery method
SE375007B (nl) * 1972-11-30 1975-04-07 Pharmacia Ab
US3875300A (en) * 1972-12-18 1975-04-01 Ortho Pharma Corp Composition for sustained release of a medicament and method of using same
US3911098A (en) * 1974-02-11 1975-10-07 American Cyanamid Co Medicament carrier

Also Published As

Publication number Publication date
HK282A (en) 1982-01-15
PT65389B (en) 1978-06-09
PT65389A (en) 1976-08-01
BE844544A (fr) 1977-01-27
JPS6122975B2 (nl) 1986-06-03
JPS5215811A (en) 1977-02-05
FR2319375B1 (nl) 1982-07-23
DE2633988C2 (de) 1986-09-11
AU1607776A (en) 1978-01-26
GB1543189A (en) 1979-03-28
BR7604876A (pt) 1977-08-09
ES461216A1 (es) 1978-05-01
FR2319375A1 (fr) 1977-02-25
IT1062653B (it) 1984-10-20
AU509140B2 (en) 1980-04-24
SE431508B (sv) 1984-02-13
CH631891A5 (en) 1982-09-15
ES461217A1 (es) 1978-05-01
SE7608036L (sv) 1977-01-30
US4343787A (en) 1982-08-10
NL7607704A (nl) 1977-02-01
DE2633988A1 (de) 1977-02-10
CY1137A (en) 1982-05-07
NL188266B (nl) 1991-12-16
ES450002A1 (es) 1977-11-16

Similar Documents

Publication Publication Date Title
NL188266C (nl) Werkwijze ter bereiding van een oogheelkundig inplantaat.
NL7608543A (nl) Werkwijze ter bereiding van entcopolymeren.
NL7613431A (nl) Werkwijze voor de bereiding van o-hydroxybenzal- dehyden.
NL7515172A (nl) Werkwijze ter bereiding van algiciden.
NL7607938A (nl) Werkwijze ter bereiding van poedervormige rubber.
NL7610066A (nl) Werkwijze voor de bereiding van amidoxim deri- vaten.
NL7608674A (nl) Werkwijze voor de bereiding van canthaxanthine.
NL7607368A (nl) Werkwijze voor de bereiding van een aldohexu- ronzuur bevattende zoetstof.
NL7606994A (nl) Werkwijze voor de bereiding van acylcyaniden.
NL7604395A (nl) Werkwijze ter bereiding van uitvlokmiddelen.
NL7600126A (nl) Werkwijze ter bereiding van fosgeen.
NL7611424A (nl) Werkwijze voor de bereiding van ethylvanadaat.
NL7609939A (nl) Werkwijze voor de bereiding van n-acylhydroxyaryl- glycinen.
NL7600512A (nl) Werkwijze voor de bereiding van 2-aminobutanol-1.
NL7602330A (nl) Werkwijze ter bereiding van dithioazolen of azolinen.
NL7600513A (nl) Werkwijze ter bereiding van ergolinederivaten.
NL7603661A (nl) Werkwijze ter bereiding van desinfecteermiddelen.
NL184952C (nl) Werkwijze voor de bereiding van cyclohexanonoxim.
NL7611271A (nl) Werkwijze voor de bereiding van 4-alkylthio- semicarbaziden.
NL7607505A (nl) Werkwijze voor de bereiding van sulfamylbenzyl- aminen.
NL7608503A (nl) Werkwijze ter bereiding van een anti-ontstekings- middel.
NL7602269A (nl) Werkwijze voor de bereiding van entpolymeren.
NL186160C (nl) Werkwijze voor de bereiding van theaspiran.
NL7603591A (nl) Werkwijze ter bereiding van fosfornitriden.
NL7602318A (nl) Werkwijze voor de bereiding van luminescerende stoffen.

Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
V4 Discontinued because of reaching the maximum lifetime of a patent

Free format text: 960712