FR2319375A1 - Insert opht - Google Patents

Insert opht

Info

Publication number
FR2319375A1
FR2319375A1 FR7622694A FR7622694A FR2319375A1 FR 2319375 A1 FR2319375 A1 FR 2319375A1 FR 7622694 A FR7622694 A FR 7622694A FR 7622694 A FR7622694 A FR 7622694A FR 2319375 A1 FR2319375 A1 FR 2319375A1
Authority
FR
France
Prior art keywords
opht
insert
insert opht
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7622694A
Other languages
English (en)
Other versions
FR2319375B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of FR2319375A1 publication Critical patent/FR2319375A1/fr
Application granted granted Critical
Publication of FR2319375B1 publication Critical patent/FR2319375B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A61K31/79—Polymers of vinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR7622694A 1975-07-29 1976-07-26 Insert opht Granted FR2319375A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60016875A 1975-07-29 1975-07-29

Publications (2)

Publication Number Publication Date
FR2319375A1 true FR2319375A1 (fr) 1977-02-25
FR2319375B1 FR2319375B1 (fr) 1982-07-23

Family

ID=24402570

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7622694A Granted FR2319375A1 (fr) 1975-07-29 1976-07-26 Insert opht

Country Status (16)

Country Link
US (1) US4343787A (fr)
JP (1) JPS5215811A (fr)
AU (1) AU509140B2 (fr)
BE (1) BE844544A (fr)
BR (1) BR7604876A (fr)
CH (1) CH631891A5 (fr)
CY (1) CY1137A (fr)
DE (1) DE2633988C2 (fr)
ES (3) ES450002A1 (fr)
FR (1) FR2319375A1 (fr)
GB (1) GB1543189A (fr)
HK (1) HK282A (fr)
IT (1) IT1062653B (fr)
NL (1) NL188266C (fr)
PT (1) PT65389B (fr)
SE (1) SE431508B (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0561695A1 (fr) * 1992-03-20 1993-09-22 Vetoquinol S.A. Insert ophtalmique bioadhésif
US5773021A (en) * 1994-03-14 1998-06-30 Vetoquinol S.A. Bioadhesive ophthalmic insert

Families Citing this family (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54145207A (en) * 1978-04-30 1979-11-13 Agency Of Ind Science & Technol High viscosity eye lotion
US4436730A (en) 1979-06-25 1984-03-13 Polymer Technology Corporation Ionic opthalmic cellulose polymer solutions
US4730013A (en) * 1981-10-08 1988-03-08 Merck & Co., Inc. Biosoluble ocular insert
FI831399L (fi) * 1982-04-29 1983-10-30 Agripat Sa Kontaktlins av haerdad polyvinylalkohol
EP0108661A1 (fr) * 1982-10-04 1984-05-16 Merck & Co. Inc. Insertions oculaires en hydroxypropyl cellulose stabilisées et procédé de stérilisation
US4565198A (en) * 1983-12-27 1986-01-21 Barnes-Hind, Inc. Method for altering the curvature of the cornea
US4660546A (en) * 1984-11-07 1987-04-28 Robert S. Herrick Method for treating for deficiency of tears
US5209927A (en) * 1985-01-23 1993-05-11 Alcon Laboratories, Inc. Ophthalmic solution
US4826871A (en) * 1985-03-13 1989-05-02 Gressel Philip D Topical ophthalmic compositions containing one or more retinoids
FR2588189B1 (fr) * 1985-10-03 1988-12-02 Merck Sharp & Dohme Composition pharmaceutique de type a transition de phase liquide-gel
US4883658A (en) * 1986-04-28 1989-11-28 Holly Frank J Ophthalmic solution for treatment of dry-eye syndrome
US4744980A (en) * 1986-04-28 1988-05-17 Holly Frank J Ophthalmic solution for treatment of dry eye syndrome
US5229128A (en) * 1986-06-11 1993-07-20 Haddad Heskel M Drug delivery ophthalmic insert and method of preparing same
US5322691A (en) * 1986-10-02 1994-06-21 Sohrab Darougar Ocular insert with anchoring protrusions
US5989579A (en) * 1986-10-02 1999-11-23 Escalon Medical Corp. Ocular insert with anchoring protrusions
GB8623661D0 (en) * 1986-10-02 1986-11-05 Darougar S Ocular insert
US4966773A (en) * 1986-11-25 1990-10-30 Alcon Laboratories, Inc. Topical ophthalmic compositions containing microfine retinoid particles
CA1317226C (fr) * 1987-05-04 1993-05-04 Phillip E. Pennell Liquide visco-elastique pour chirurgie ophtalmique et methode d'utilisation
US5075104A (en) * 1989-03-31 1991-12-24 Alcon Laboratories, Inc. Ophthalmic carboxy vinyl polymer gel for dry eye syndrome
GB8917216D0 (en) * 1989-07-27 1989-09-13 Smith & Nephew Ophthalmic composition
MY113268A (en) 1992-12-29 2002-01-31 Insite Vision Incorporated Plasticized bioerodible controlled delivery system
RU2145882C1 (ru) * 1993-04-30 2000-02-27 С.Уэбб Брэдфорд Синтетический вязкоэластичный материал для применения в офтальмологии
US5631004A (en) * 1993-09-30 1997-05-20 Alcon Laboratories, Inc. Use of sustained release antibiotic compositions in ophthalmic surgical procedures
TW274516B (fr) * 1993-11-12 1996-04-21 Ciba Geigy Ag
US5466233A (en) * 1994-04-25 1995-11-14 Escalon Ophthalmics, Inc. Tack for intraocular drug delivery and method for inserting and removing same
US5472436A (en) * 1994-07-26 1995-12-05 Fremstad; Daria A. Ocular appliance for delivering medication
US5516808A (en) * 1994-10-27 1996-05-14 Sawaya; Assad S. Topical cellulose pharmaceutical formulation
US5518732A (en) * 1995-02-14 1996-05-21 Chiron Vision, Inc. Bio-erodible ophthalmic shield
DE19508029C2 (de) * 1995-03-07 1997-10-09 Richard Prof Dr Sueverkruep Darreichungsform zur äußerlichen Applikation von ophthalmischen Arzneistoffen und Verfahren zur Herstellung derselben
US6299895B1 (en) 1997-03-24 2001-10-09 Neurotech S.A. Device and method for treating ophthalmic diseases
US5888493A (en) * 1996-12-05 1999-03-30 Sawaya; Assad S. Ophthalmic aqueous gel formulation and related methods
US6193991B1 (en) * 1997-10-29 2001-02-27 Atul J. Shukla Biodegradable delivery systems of biologically active substances
JP2002538124A (ja) 1999-03-01 2002-11-12 ヴィスタ サイエンティフィック エルエルシー ムチンを含む眼科用調合物
US6264971B1 (en) 1999-11-04 2001-07-24 Btg International Limited Ocular insert
US20050042194A1 (en) 2000-05-11 2005-02-24 A.P. Pharma, Inc. Semi-solid delivery vehicle and pharmaceutical compositions
US6613355B2 (en) 2000-05-11 2003-09-02 A.P. Pharma, Inc. Semi-solid delivery vehicle and pharmaceutical compositions
JP2004511431A (ja) * 2000-06-28 2004-04-15 アトゥル・ジェイ・シュクラ 生物活性物質を含む生分解性ビヒクルおよび送達システム
US7404825B2 (en) * 2001-06-11 2008-07-29 Herrick Ii Robert S Implant capable of forming a differential image in an eye
ATE506929T1 (de) 2001-06-12 2011-05-15 Univ Johns Hopkins Med Reservoirvorrichtung für die intraokulare arzneimittelabgabe
FR2833493B1 (fr) * 2001-12-18 2005-09-23 Ioltechnologie Production Forme galenique solide et soluble pour l'administration occulaire de principes actifs et procede de fabrication d'un insert ophtalmique solide et soluble
MXPA04011416A (es) * 2002-05-17 2005-09-30 Othera Pharmaceuticals Inc Mejora del desarrollo de las cataratas y otras enfermedades oftalmicas.
US7795203B2 (en) * 2002-09-30 2010-09-14 Babizhayev Mark A Method for topical treatment of eye disease and composition and device for said treatment
DE10246900A1 (de) 2002-10-08 2004-04-22 Horstmann, Michael, Dr. Am Auge applizierbare Vorrichtung zur sicheren Dosierung systemischer und tropischer Medikation
US7825134B2 (en) * 2003-05-19 2010-11-02 Othera Holding, Inc. Amelioration of cataracts, macular degeneration and other ophthalmic diseases
US7914803B2 (en) 2003-06-13 2011-03-29 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of three polymers
US7947295B2 (en) * 2003-06-13 2011-05-24 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers
KR101147046B1 (ko) * 2003-06-13 2012-05-22 알콘, 인코퍼레이티드 시너지성의 2개의 폴리머 배합물을 포함하는 안과용 조성물
TWI336257B (en) * 2003-06-13 2011-01-21 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
WO2005018608A1 (fr) * 2003-08-20 2005-03-03 Santen Pharmaceutical Co., Ltd. Systeme d'administration de produit pharmaceutique pour administrer de fins grains sous la capsule de tenon
WO2005020907A2 (fr) 2003-08-26 2005-03-10 Vista Scientific Dispositif d'administration oculaire de produit pharmaceutique
US20060020253A1 (en) * 2004-07-26 2006-01-26 Prescott Anthony D Implantable device having reservoir with controlled release of medication and method of manufacturing the same
US7117870B2 (en) * 2004-07-26 2006-10-10 Clarity Corporation Lacrimal insert having reservoir with controlled release of medication and method of manufacturing the same
US20060067978A1 (en) * 2004-09-29 2006-03-30 Bausch & Lomb Incorporated Process for preparing poly(vinyl alcohol) drug delivery devices
US20060068012A1 (en) * 2004-09-29 2006-03-30 Bausch & Lomb Incorporated Process for preparing poly (vinyl alcohol) drug delivery devices with humidity control
CA2617040A1 (fr) * 2005-07-29 2007-02-01 Santen Pharmaceutical Co., Ltd. Systeme non invasif d'administration de medicament qui vise le tissu posterieur de l'oeil au moyen d'une composition solide
US20070264339A1 (en) * 2006-05-12 2007-11-15 Ap Pharma, Inc. Base-stabilized polyorthoester formulations
US20070265329A1 (en) * 2006-05-12 2007-11-15 Devang Shah T Methods for the prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV)
US20070264338A1 (en) * 2006-05-12 2007-11-15 Shah Devang T Base-stabilized polyorthoester formulations
US20080193407A1 (en) * 2007-02-09 2008-08-14 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of three polymers
AU2008218783A1 (en) 2007-02-22 2008-08-28 Colby Pharmaceutical Company Hydroxylamine compounds and methods of their use
BRPI0922189A2 (pt) * 2008-12-11 2018-10-23 A P Pharma Inc "métodos para aumentar a estabilidade de poliortoésteres e suas formulações".
US8623395B2 (en) 2010-01-29 2014-01-07 Forsight Vision4, Inc. Implantable therapeutic device
US8399006B2 (en) 2009-01-29 2013-03-19 Forsight Vision4, Inc. Posterior segment drug delivery
WO2010101758A1 (fr) * 2009-03-03 2010-09-10 Alcon Research, Ltd. Dispositif péricornéen d'administration de médicaments
WO2010141729A1 (fr) 2009-06-03 2010-12-09 Forsight Labs, Llc Distribution de médicament de segment antérieur
EP2486128A4 (fr) * 2009-10-08 2013-10-09 Neurotech Usa Inc Utilisation du pedf dans un système d'administration à base de cellules encapsulées
WO2011094170A1 (fr) * 2010-01-27 2011-08-04 Alcon Research, Ltd. Dispositif d'administration de médicaments péricornéens par intermittence
US10166142B2 (en) 2010-01-29 2019-01-01 Forsight Vision4, Inc. Small molecule delivery with implantable therapeutic device
WO2011163560A1 (fr) 2010-06-25 2011-12-29 The U.S.A., As Represented By The Secretary, Department Of Health And Human Services Méthodes de traitement utilisant l'acide sterculique
KR102080704B1 (ko) 2010-07-29 2020-02-24 세센 바이오, 아이엔씨. 키메라 il-1 수용체 유형 i 항진제 및 길항제들
CN103153316B (zh) 2010-08-05 2015-08-19 弗赛特影像4股份有限公司 组合药物递送方法和设备
US9492315B2 (en) 2010-08-05 2016-11-15 Forsight Vision4, Inc. Implantable therapeutic device
PL2600930T3 (pl) 2010-08-05 2021-09-06 Forsight Vision4, Inc. Urządzenie wstrzykujące do dostarczania leku
EP2640360A2 (fr) 2010-11-19 2013-09-25 Forsight Vision4, Inc. Formulations d'agents thérapeutiques pour des dispositifs implantés
US10398592B2 (en) 2011-06-28 2019-09-03 Forsight Vision4, Inc. Diagnostic methods and apparatus
WO2013040238A2 (fr) 2011-09-13 2013-03-21 Vista Scientific Llc Dispositifs d'administration de médicaments oculaires à libération prolongée et procédés de fabrication correspondants
AU2012308317B2 (en) 2011-09-14 2017-01-05 Forsight Vision5, Inc. Ocular insert apparatus and methods
ES2864203T3 (es) 2011-09-16 2021-10-13 Forsight Vision4 Inc Aparato de intercambio de fluido
EP2911623B1 (fr) 2012-10-26 2019-08-14 Forsight Vision5, Inc. Système ophtalmique pour la libération prolongée de médicament dans l' oeil
ES2884813T3 (es) 2013-03-13 2021-12-13 Buzzard Pharmaceuticals AB Formulaciones de citoquina quimérica para administración ocular
WO2014152959A1 (fr) 2013-03-14 2014-09-25 Forsight Vision4, Inc. Systèmes pour l'administration intra-oculaire entretenue de composés à faible solubilité provenant d'un implant de système de pose d'orifice
EP2978393B1 (fr) 2013-03-28 2023-12-27 ForSight Vision4, Inc. Implant ophtalmique pour administrer des substances thérapeutiques
RU2017105844A (ru) 2014-08-08 2018-09-11 Форсайт Вижн4, Инк. Стабильные и растворимые составы ингибиторов рецепторных тирозинкиназ и способы их получения
JP7037360B2 (ja) 2014-11-10 2022-03-16 フォーサイト・ビジョン フォー・インコーポレーテッド 拡張可能な薬物送達デバイス
EP3283004A4 (fr) 2015-04-13 2018-12-05 Forsight Vision5, Inc. Composition d'insert oculaire d'agent pharmaceutiquement actif cristallin ou semi-cristallin
US10010502B2 (en) 2015-05-19 2018-07-03 Amorphex Therapeutics Llc Device that delivers a sustained low-dose of a myopia-suppressing drug, while preserving pupillary function and accommodation
EP3377009B1 (fr) 2015-11-20 2020-10-28 ForSight Vision4, Inc. Structures poreuses pour dispositifs d'administration de médicament à libération prolongée
EP3439591B1 (fr) 2016-04-05 2020-09-23 ForSight Vision4, Inc. Dispositifs implantables d'administration de médicaments par voie oculaire
KR20200093581A (ko) 2017-11-21 2020-08-05 포사이트 비젼4, 인크. 확장 가능한 포트 전달 시스템을 위한 유체 교환 기기 및 사용 방법
WO2023214027A1 (fr) 2022-05-06 2023-11-09 Eyed Pharma Insert pour le traitement des yeux secs
BE1030503B1 (fr) 2022-05-06 2023-12-04 Eyed Pharma Insert pour le traitement de la sécheresse oculaire
BE1030504B1 (fr) 2022-05-06 2023-12-04 Eyed Pharma Insert composite pour le traitement de la sécheresse oculaire

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US3856919A (en) * 1970-06-08 1974-12-24 Burton Parsons Chemicals Inc Ophthalmic solution
US3767788A (en) * 1970-06-08 1973-10-23 Burton Parsons Chemicals Inc Ophthalmic solution
SE352811B (fr) * 1971-06-04 1973-01-15 Pharmacia Ab
US3845201A (en) * 1972-04-24 1974-10-29 S Loucas Solid state ophthalmic medication delivery method
SE375007B (fr) * 1972-11-30 1975-04-07 Pharmacia Ab
US3875300A (en) * 1972-12-18 1975-04-01 Ortho Pharma Corp Composition for sustained release of a medicament and method of using same
US3911098A (en) * 1974-02-11 1975-10-07 American Cyanamid Co Medicament carrier

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0561695A1 (fr) * 1992-03-20 1993-09-22 Vetoquinol S.A. Insert ophtalmique bioadhésif
FR2688694A1 (fr) * 1992-03-20 1993-09-24 Vetoquinol Sa Insert ophtalmique bioadhesif.
US5773021A (en) * 1994-03-14 1998-06-30 Vetoquinol S.A. Bioadhesive ophthalmic insert

Also Published As

Publication number Publication date
BR7604876A (pt) 1977-08-09
HK282A (en) 1982-01-15
NL188266C (nl) 1992-05-18
SE431508B (sv) 1984-02-13
BE844544A (fr) 1977-01-27
IT1062653B (it) 1984-10-20
US4343787A (en) 1982-08-10
ES461217A1 (es) 1978-05-01
DE2633988C2 (de) 1986-09-11
GB1543189A (en) 1979-03-28
ES461216A1 (es) 1978-05-01
FR2319375B1 (fr) 1982-07-23
CY1137A (en) 1982-05-07
AU509140B2 (en) 1980-04-24
DE2633988A1 (de) 1977-02-10
CH631891A5 (en) 1982-09-15
AU1607776A (en) 1978-01-26
PT65389B (en) 1978-06-09
SE7608036L (sv) 1977-01-30
PT65389A (en) 1976-08-01
JPS6122975B2 (fr) 1986-06-03
NL7607704A (nl) 1977-02-01
ES450002A1 (es) 1977-11-16
NL188266B (nl) 1991-12-16
JPS5215811A (en) 1977-02-05

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Legal Events

Date Code Title Description
CC Supplementary protection certificate (spc) laid open to the public (law of 25 june 1990)

Free format text: 92C0044, 920318

CB Supplementary protection certificate (spc) granted (law of 25 june 1990)

Free format text: 92C0044, 760726

CL Concession to grant licences