MY169320A - Method and device for treating blood cholesterol disorders - Google Patents

Method and device for treating blood cholesterol disorders

Info

Publication number
MY169320A
MY169320A MYPI2013700376A MYPI2013700376A MY169320A MY 169320 A MY169320 A MY 169320A MY PI2013700376 A MYPI2013700376 A MY PI2013700376A MY PI2013700376 A MYPI2013700376 A MY PI2013700376A MY 169320 A MY169320 A MY 169320A
Authority
MY
Malaysia
Prior art keywords
levels
treatment
plasmapheresis
patients
composition
Prior art date
Application number
MYPI2013700376A
Inventor
Lucas Victor Grifols
Roura Victor Grifols
Original Assignee
Grifols Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grifols Sa filed Critical Grifols Sa
Publication of MY169320A publication Critical patent/MY169320A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3496—Plasmapheresis; Leucopheresis; Lymphopheresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/38—Removing constituents from donor blood and storing or returning remainder to body, e.g. for transfusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/75—General characteristics of the apparatus with filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/12—Blood circulatory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Obesity (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention refers to a composition and a device comprising whole blood cells for treating cholesterol disorders for use in a method comprising administering at least one treatment regime including two or more rounds of plasmapheresis to a patient having abnonnal total cholesterol, abnomial LDL levels and/or abnormal HDL levels prior to treatment. Treatment with said composition and device results in decreased LDL levels in patients having abnormal LDL levels and increased HDL levels in patients having abnom1al HDL levels. Each subsequent round of plasmapheresis is conducted weekly, but no more than twice per week. FIG.3
MYPI2013700376A 2012-03-12 2013-03-08 Method and device for treating blood cholesterol disorders MY169320A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13/418,123 US10624924B2 (en) 2012-03-12 2012-03-12 Method and device for treating blood cholesterol disorders

Publications (1)

Publication Number Publication Date
MY169320A true MY169320A (en) 2019-03-21

Family

ID=47891413

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI2013700376A MY169320A (en) 2012-03-12 2013-03-08 Method and device for treating blood cholesterol disorders

Country Status (24)

Country Link
US (1) US10624924B2 (en)
EP (1) EP2638918B1 (en)
JP (1) JP6218401B2 (en)
KR (2) KR20130105452A (en)
CN (2) CN103301520A (en)
AR (1) AR090295A1 (en)
AU (1) AU2013201550B2 (en)
BR (1) BR102013005877B1 (en)
CA (1) CA2809012C (en)
CL (1) CL2013000667A1 (en)
ES (1) ES2598241T3 (en)
HK (1) HK1185791A1 (en)
HU (1) HUE029681T2 (en)
IL (1) IL225129A (en)
MX (1) MX344112B (en)
MY (1) MY169320A (en)
NZ (1) NZ608133A (en)
PL (1) PL2638918T3 (en)
PT (1) PT2638918T (en)
RU (1) RU2625774C2 (en)
SG (1) SG193729A1 (en)
TW (1) TWI554275B (en)
UY (1) UY34667A (en)
ZA (1) ZA201301815B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10624924B2 (en) 2012-03-12 2020-04-21 Grifols, S.A. Method and device for treating blood cholesterol disorders
AU2015201496B2 (en) * 2014-06-03 2019-10-31 Grifols Worldwide Operations Limited Use of plasmapheresis to treat blood pressure disorders

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US4350156A (en) 1980-05-29 1982-09-21 Japan Foundation For Artificial Organs Method and apparatus for on-line filtration removal of macromolecules from a physiological fluid
US4540401A (en) * 1983-02-22 1985-09-10 Applied Immune Sciences, Inc. In vivo therapeutic apheresis using lipid vesicles
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Also Published As

Publication number Publication date
MX344112B (en) 2016-11-30
BR102013005877B1 (en) 2021-10-26
IL225129A (en) 2017-02-28
AU2013201550B2 (en) 2015-07-02
HUE029681T2 (en) 2017-02-28
TWI554275B (en) 2016-10-21
SG193729A1 (en) 2013-10-30
BR102013005877A2 (en) 2017-07-11
US20130236559A1 (en) 2013-09-12
ES2598241T3 (en) 2017-01-26
MX2013002681A (en) 2013-09-12
CL2013000667A1 (en) 2013-07-12
RU2625774C2 (en) 2017-07-18
JP2013188475A (en) 2013-09-26
JP6218401B2 (en) 2017-10-25
HK1185791A1 (en) 2014-02-28
US10624924B2 (en) 2020-04-21
CA2809012A1 (en) 2013-09-12
TW201340973A (en) 2013-10-16
IL225129A0 (en) 2013-06-27
EP2638918A1 (en) 2013-09-18
KR101908899B1 (en) 2018-10-16
AR090295A1 (en) 2014-11-05
PL2638918T3 (en) 2017-01-31
RU2013110503A (en) 2014-09-20
EP2638918B1 (en) 2016-08-31
KR20130105452A (en) 2013-09-25
UY34667A (en) 2013-10-31
KR20180074646A (en) 2018-07-03
ZA201301815B (en) 2013-11-27
NZ608133A (en) 2014-09-26
PT2638918T (en) 2016-10-24
AU2013201550A1 (en) 2013-09-26
CN107754038A (en) 2018-03-06
CA2809012C (en) 2020-04-14
CN103301520A (en) 2013-09-18

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