MXPA02009551A - Profarmacos de derivados de imidazopiridina. - Google Patents

Profarmacos de derivados de imidazopiridina.

Info

Publication number
MXPA02009551A
MXPA02009551A MXPA02009551A MXPA02009551A MXPA02009551A MX PA02009551 A MXPA02009551 A MX PA02009551A MX PA02009551 A MXPA02009551 A MX PA02009551A MX PA02009551 A MXPA02009551 A MX PA02009551A MX PA02009551 A MXPA02009551 A MX PA02009551A
Authority
MX
Mexico
Prior art keywords
prodrugs
imidazopyridine derivatives
imidazopyridine
derivatives
substituents
Prior art date
Application number
MXPA02009551A
Other languages
English (en)
Inventor
Joerg Senn-Bilfinger
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of MXPA02009551A publication Critical patent/MXPA02009551A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Abstract

Se describen compuestos de la formula (1), en donde los substituyentes tienen los significados mencionados en la descripcion y son adecuados para la prevencion y tratamiento de enfermedades gastrointestinales. (Ver formula 1).
MXPA02009551A 2000-03-29 2001-03-28 Profarmacos de derivados de imidazopiridina. MXPA02009551A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00106695 2000-03-29
PCT/EP2001/003514 WO2001072756A1 (en) 2000-03-29 2001-03-28 Prodrugs of imidazopyridine derivatives

Publications (1)

Publication Number Publication Date
MXPA02009551A true MXPA02009551A (es) 2004-05-14

Family

ID=8168271

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02009551A MXPA02009551A (es) 2000-03-29 2001-03-28 Profarmacos de derivados de imidazopiridina.

Country Status (26)

Country Link
US (2) US20030125327A1 (es)
EP (1) EP1313740B1 (es)
JP (1) JP2003528878A (es)
KR (1) KR100860627B1 (es)
CN (1) CN1214030C (es)
AT (1) ATE311389T1 (es)
AU (1) AU783633B2 (es)
BR (1) BR0109483A (es)
CA (1) CA2404474A1 (es)
CZ (1) CZ20023194A3 (es)
DE (1) DE60115466T2 (es)
DK (1) DK1313740T3 (es)
EA (1) EA005597B1 (es)
ES (1) ES2253376T3 (es)
HK (1) HK1056175A1 (es)
HR (1) HRP20020854A2 (es)
HU (1) HUP0302331A2 (es)
IL (2) IL151200A0 (es)
MX (1) MXPA02009551A (es)
NO (1) NO20024662D0 (es)
NZ (1) NZ520837A (es)
PL (1) PL365116A1 (es)
SI (1) SI1313740T1 (es)
SK (1) SK286850B6 (es)
WO (1) WO2001072756A1 (es)
ZA (1) ZA200207637B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ20023116A3 (cs) * 2000-03-29 2003-01-15 Altana Pharma Ag Alkylované imidazopyridinové sloučeniny
EP1332143A1 (en) * 2000-10-25 2003-08-06 ALTANA Pharma AG Polysubstituted imidazopyridines as gastric secretion inhibitors
US20050020637A1 (en) * 2001-11-19 2005-01-27 Wolfgang-Alexander Simon Agents for the treatment of airway disorders
JP2005519933A (ja) 2002-02-15 2005-07-07 アルタナ　ファルマ　アクチエンゲゼルシャフト 三環式ｎ−アシル化合物
TWI295575B (en) * 2002-04-24 2008-04-11 Altana Pharma Ag Nitrosated imidazopyridines
EP1506016A2 (en) * 2002-05-07 2005-02-16 ALTANA Pharma AG New combination of reversible proton pump inhibitors and airway therapeutics for treating airway disorders
PL375567A1 (en) 2002-11-19 2005-11-28 Altana Pharma Ag 8-substituted imidazopyridines
EP1585516A2 (en) * 2002-12-20 2005-10-19 ALTANA Pharma AG 8-trialkylsiloxy-2-methyl-9-phenyl-7-oxo-7,8,9,10-tetrahydroimidazo[1,2-h][1,7]naphthyridines
JP2006517952A (ja) * 2003-02-17 2006-08-03 アルタナ　ファルマ　アクチエンゲゼルシャフト 新規の組合せ物及び選択された医薬有効化合物の新規の使用
AR044129A1 (es) 2003-05-06 2005-08-24 Altana Pharma Ag Compuestos intermedios de imidazopiridina. proceso de preparacion.
SA04250092B1 (ar) * 2003-05-14 2008-05-04 التانا فاروا ايه جي مركب وسيط جديد لتحضير مركبات إيميدازوبيريدين imidazopyridines فعالة علاجياً
CA2526566A1 (en) * 2003-05-27 2004-12-09 Altana Pharma Ag Pharmaceutical combinations of a proton pump inhibitor and a compound which modifies gastrointestinal motility
AU2004285394B2 (en) 2003-11-03 2009-01-08 Astrazeneca Ab Imidazo (1,2-A) pyridine derivatives for the treatment of silent gastro-esophageal reflux
AR046893A1 (es) * 2003-12-16 2005-12-28 Altana Pharma Ag Bencimidazoles triciclicos
CA2549860A1 (en) 2003-12-19 2005-06-30 Altana Pharma Ag Intermediates for the preparation of tricyclic dihydropyrano -imidazo -pyridines derivatives
CN101027277A (zh) * 2004-07-23 2007-08-29 帝斯曼知识产权资产管理有限公司 (2r,3r)－2－羟基－3－氨基－3－芳基－丙酰胺和(2r,3r)－2－羟基－3－氨基－3－芳基－丙酸烷基酯的制备方法
AU2005291284A1 (en) * 2004-10-01 2006-04-13 Altana Pharma Ag Substituted tricyclic benzimidazoles
BRPI1013288A2 (pt) 2009-07-09 2016-03-29 Raqualia Pharma Inc uso de um composto, método de composição farmacêutica para o tratamento de doenças em que a motilidade gastrointestinal anormal está envolvida, kit e embalagem comercial que compreende uma composição farmacêutica contendo o composto

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468400A (en) * 1982-12-20 1984-08-28 Schering Corporation Antiulcer tricyclic imidazo [1,2-a]pyridines
US4673679A (en) * 1986-05-14 1987-06-16 E. I. Du Pont De Nemours And Company Use of prodrugs of 3-hydroxymorphinans to prevent bitter taste upon buccal, nasal or sublingual administration
JPH06502659A (ja) * 1991-05-31 1994-03-24 ファイザー　インク 免疫抑制剤としてのラパマイシンプロドラッグの使用
DE4308095A1 (de) * 1993-03-13 1994-09-15 Hoechst Ag Prodrug-Derivate von Arzneimittelwirkstoffen mit Hydroxylgruppen, Verfahren zu deren Herstellung und ihre Verwendung
SE9401197D0 (sv) * 1994-04-11 1994-04-11 Astra Ab Active compounds
US6073004A (en) 1996-12-17 2000-06-06 Ericsson Inc. Emergency call initiator
EE03771B1 (et) * 1997-03-24 2002-06-17 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahüdropüridoühendid, neid sisaldav ravim ja nende kasutamine
CN101255164A (zh) * 1997-05-28 2008-09-03 奥坦纳医药公司 稠合的二氢吡喃类化合物及其用途
HUP0001555A3 (en) * 1997-10-30 2001-01-29 Altana Pharma Ag Tetrahydro-imidazo-naphthyridine derivatives, pharmaceutical compositions thereof and process for their preparation
TR200100805T2 (tr) * 1998-09-23 2001-08-21 Byk Gulden Lomberg Chemische Fabr�K Gmbh Tetrahidropiridoeterler
DE69938192D1 (en) * 1998-11-03 2008-04-03 Nycomed Gmbh Imidazonaphthyridine
CZ20023116A3 (cs) 2000-03-29 2003-01-15 Altana Pharma Ag Alkylované imidazopyridinové sloučeniny

Also Published As

Publication number Publication date
SK286850B6 (sk) 2009-06-05
EA005597B1 (ru) 2005-04-28
CZ20023194A3 (cs) 2003-01-15
NO20024662L (no) 2002-09-27
CN1214030C (zh) 2005-08-10
HK1056175A1 (en) 2004-02-06
US7189736B2 (en) 2007-03-13
AU6016601A (en) 2001-10-08
BR0109483A (pt) 2003-06-10
EA200200875A1 (ru) 2003-04-24
ATE311389T1 (de) 2005-12-15
KR100860627B1 (ko) 2008-09-29
SK13852002A3 (sk) 2003-02-04
KR20020084262A (ko) 2002-11-04
DK1313740T3 (da) 2006-04-03
US20040198764A1 (en) 2004-10-07
ZA200207637B (en) 2004-04-08
WO2001072756A1 (en) 2001-10-04
IL151200A0 (en) 2003-04-10
HUP0302331A2 (hu) 2003-12-29
DE60115466T2 (de) 2006-07-20
EP1313740A1 (en) 2003-05-28
CN1426414A (zh) 2003-06-25
NZ520837A (en) 2005-01-28
PL365116A1 (en) 2004-12-27
US20030125327A1 (en) 2003-07-03
SI1313740T1 (sl) 2006-04-30
CA2404474A1 (en) 2001-10-04
EP1313740B1 (en) 2005-11-30
ES2253376T3 (es) 2006-06-01
JP2003528878A (ja) 2003-09-30
DE60115466D1 (de) 2006-01-05
NO20024662D0 (no) 2002-09-27
AU783633B2 (en) 2005-11-17
IL151200A (en) 2009-11-18
HRP20020854A2 (en) 2004-12-31

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