MX369646B - Sal de derivado de piridina monociclico y su cristal. - Google Patents

Sal de derivado de piridina monociclico y su cristal.

Info

Publication number
MX369646B
MX369646B MX2017001624A MX2017001624A MX369646B MX 369646 B MX369646 B MX 369646B MX 2017001624 A MX2017001624 A MX 2017001624A MX 2017001624 A MX2017001624 A MX 2017001624A MX 369646 B MX369646 B MX 369646B
Authority
MX
Mexico
Prior art keywords
salt
crystal
pyridine derivative
monocyclic pyridine
monocyclic
Prior art date
Application number
MX2017001624A
Other languages
English (en)
Other versions
MX2017001624A (es
Inventor
Yoshida Kenshi
Ozaki Shunsuke
Original Assignee
Eisai R&D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Publication of MX2017001624A publication Critical patent/MX2017001624A/es
Publication of MX369646B publication Critical patent/MX369646B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
    • C07C55/02—Dicarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
    • C07C55/02—Dicarboxylic acids
    • C07C55/10—Succinic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

La presente invención proporciona sales que consisten en un ácido organocarboxílico seleccionado entre el grupo que consiste en ácido succínico y ácido maleico y un compuesto representado por medio de la fórmula (I) (ver Fórmula) y sus cristales, que se pueden usar como materiales brutos para sustancias farmacéuticas.
MX2017001624A 2014-08-18 2015-08-17 Sal de derivado de piridina monociclico y su cristal. MX369646B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2014166118 2014-08-18
PCT/JP2015/073047 WO2016027781A1 (ja) 2014-08-18 2015-08-17 単環ピリジン誘導体の塩およびその結晶

Publications (2)

Publication Number Publication Date
MX2017001624A MX2017001624A (es) 2017-04-27
MX369646B true MX369646B (es) 2019-11-15

Family

ID=55350725

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017001624A MX369646B (es) 2014-08-18 2015-08-17 Sal de derivado de piridina monociclico y su cristal.

Country Status (14)

Country Link
US (1) US9951047B2 (es)
EP (1) EP3184520B1 (es)
JP (1) JP5925978B1 (es)
KR (1) KR102344105B1 (es)
CN (1) CN106660997B (es)
AU (1) AU2015304465B2 (es)
BR (1) BR112017002268B1 (es)
CA (1) CA2956270C (es)
ES (1) ES2914072T3 (es)
IL (1) IL250290B (es)
MX (1) MX369646B (es)
RU (1) RU2658821C1 (es)
SG (1) SG11201700703XA (es)
WO (1) WO2016027781A1 (es)

Families Citing this family (9)

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Publication number Priority date Publication date Assignee Title
CA3001969C (en) * 2015-12-17 2023-10-03 Eisai R&D Management Co., Ltd. Therapeutic agent for breast cancer
JP2020536846A (ja) * 2017-10-12 2020-12-17 エーザイ・アール・アンド・ディー・マネジメント株式会社 Ｆｇｆｒ選択的チロシンキナーゼ阻害剤を含む医薬組成物
JPWO2019189241A1 (ja) * 2018-03-28 2021-03-18 エーザイ・アール・アンド・ディー・マネジメント株式会社 肝細胞癌治療剤
KR20230004595A (ko) 2020-04-17 2023-01-06 에자이 알앤드디 매니지먼트 가부시키가이샤 유방암 치료제
BR112022027069A2 (pt) 2020-07-31 2023-02-07 Eisai R&D Man Co Ltd Agente terapêutico para o câncer de mama
US20230330081A1 (en) 2020-10-28 2023-10-19 Eisai R&D Management Co., Ltd. Pharmaceutical composition for treating tumors
TW202328098A (zh) 2021-08-31 2023-07-16 日商衛材R&D企管股份有限公司 單環吡啶衍生物的合成中間體之製造方法
CN117715902A (zh) 2021-08-31 2024-03-15 卫材R&D管理有限公司 单环吡啶衍生物的制造方法
WO2023174400A1 (zh) * 2022-03-18 2023-09-21 上海润石医药科技有限公司 一种取代的氨基六元氮杂环类化合物的盐及其晶型、制备方法和应用

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Also Published As

Publication number Publication date
CN106660997A (zh) 2017-05-10
IL250290A0 (en) 2017-03-30
CN106660997B (zh) 2019-05-21
CA2956270A1 (en) 2016-02-25
JPWO2016027781A1 (ja) 2017-04-27
WO2016027781A1 (ja) 2016-02-25
US9951047B2 (en) 2018-04-24
AU2015304465B2 (en) 2019-05-09
EP3184520B1 (en) 2022-03-23
MX2017001624A (es) 2017-04-27
KR102344105B1 (ko) 2021-12-29
KR20170035927A (ko) 2017-03-31
JP5925978B1 (ja) 2016-05-25
BR112017002268A2 (pt) 2017-11-21
CA2956270C (en) 2022-08-09
AU2015304465A1 (en) 2017-02-23
US20170217935A1 (en) 2017-08-03
ES2914072T3 (es) 2022-06-07
IL250290B (en) 2020-06-30
SG11201700703XA (en) 2017-03-30
EP3184520A1 (en) 2017-06-28
BR112017002268B1 (pt) 2022-11-08
EP3184520A4 (en) 2018-04-18
RU2658821C1 (ru) 2018-06-25

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