MX363730B - Procedimiento para la preparacion de derivados de acido antranilico sustituidos. - Google Patents

Procedimiento para la preparacion de derivados de acido antranilico sustituidos.

Info

Publication number
MX363730B
MX363730B MX2014009317A MX2014009317A MX363730B MX 363730 B MX363730 B MX 363730B MX 2014009317 A MX2014009317 A MX 2014009317A MX 2014009317 A MX2014009317 A MX 2014009317A MX 363730 B MX363730 B MX 363730B
Authority
MX
Mexico
Prior art keywords
acid derivatives
anthranilic acid
producing substituted
substituted anthranilic
compounds
Prior art date
Application number
MX2014009317A
Other languages
English (en)
Other versions
MX2014009317A (es
Inventor
Thomas Himmler
Sergii Pazenok
Norbert Lui
Frank Volz
Original Assignee
Bayer Ip Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ip Gmbh filed Critical Bayer Ip Gmbh
Publication of MX2014009317A publication Critical patent/MX2014009317A/es
Publication of MX363730B publication Critical patent/MX363730B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
    • C07C255/60—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton at least one of the singly-bound nitrogen atoms being acylated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención se refiere a un procedimiento para la preparación de derivados de ácido antranílico sustituidos de fórmula (I): (ver Fórmula) en la que R1, R2, R3 y R4 son cada uno como se han definido en la descripción, mediante la conversión de los compuestos de fórmula general (IV) en presencia de un catalizador de paladio y monóxido de carbono. Asimismo, la presente invención se refiere a compuestos de fórmula general (IV): (ver Fórmula).
MX2014009317A 2012-02-07 2013-02-06 Procedimiento para la preparacion de derivados de acido antranilico sustituidos. MX363730B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12154290 2012-02-07
PCT/EP2013/052350 WO2013117601A1 (de) 2012-02-07 2013-02-06 Verfahren zur herstellung von substituierten anthranilsäure-derivaten

Publications (2)

Publication Number Publication Date
MX2014009317A MX2014009317A (es) 2014-11-12
MX363730B true MX363730B (es) 2019-04-01

Family

ID=47722253

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014009317A MX363730B (es) 2012-02-07 2013-02-06 Procedimiento para la preparacion de derivados de acido antranilico sustituidos.

Country Status (10)

Country Link
US (3) US20150011772A1 (es)
EP (1) EP2812310A1 (es)
JP (2) JP2015511229A (es)
KR (1) KR102032979B1 (es)
CN (2) CN104245666B (es)
BR (1) BR112014019487A2 (es)
IL (1) IL233945A0 (es)
MX (1) MX363730B (es)
TW (1) TWI644888B (es)
WO (1) WO2013117601A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104245666B (zh) * 2012-02-07 2019-01-11 拜耳知识产权有限责任公司 取代的邻氨基苯甲酸衍生物的制备方法
WO2015162260A1 (en) * 2014-04-25 2015-10-29 Basf Se Process for preparing anthranilamide esters and derivatives
CN104961644B (zh) * 2015-05-20 2017-04-12 上海交通大学 一种制备n‑芳基酰胺化合物的方法
CN106045870B (zh) * 2016-07-07 2018-07-03 上海应用技术学院 一种制备酰胺的方法
CN109180518B (zh) * 2018-10-18 2021-05-18 陕西科技大学 一种仲/叔酰胺类化合物及其合成方法
TW202222773A (zh) 2020-09-17 2022-06-16 印度商皮埃企業有限公司 製備鄰胺苯甲酸／鄰胺苯甲醯胺化合物及其中間產物之方法

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3161456D1 (en) * 1980-02-06 1983-12-29 Hoffmann La Roche Process for the preparation of anthranilic acid derivatives
US5739330A (en) * 1996-02-05 1998-04-14 Hoechst Celanese Corporation Process for preparing quinazolones
JP2002533454A (ja) * 1998-12-23 2002-10-08 イーライ・リリー・アンド・カンパニー 芳香族アミド類
US6632815B2 (en) * 1999-09-17 2003-10-14 Millennium Pharmaceuticals, Inc. Inhibitors of factor Xa
EE200300342A (et) * 2001-01-26 2003-12-15 Bristol-Myers Squibb Company Imidasolüüli derivaadid kui kortikotropiini vabastava faktori inhibiitorid, nende saamismeetodid ning kasutamine
AR036872A1 (es) 2001-08-13 2004-10-13 Du Pont Compuesto de antranilamida, composicion que lo comprende y metodo para controlar una plaga de invertebrados
JP2004004374A (ja) 2002-05-31 2004-01-08 Canon Inc 閃光撮影装置
AU2003245464A1 (en) * 2002-06-13 2003-12-31 E.I. Du Pont De Nemours And Company Pyrazole and pyrrole carboxamide insecticides
JP2004043474A (ja) * 2002-07-05 2004-02-12 Nippon Nohyaku Co Ltd ２−アミノ安息香酸誘導体及びその製造方法
US20040068012A1 (en) * 2002-10-08 2004-04-08 Comess Kenneth M. Sulfonamides having antiangiogenic and anticancer activity
US7491718B2 (en) * 2002-10-08 2009-02-17 Abbott Laboratories Sulfonamides having antiangiogenic and anticancer activity
MX254990B (es) 2003-01-28 2008-02-27 Du Pont Insecticidas de ciano antranilamida.
US7456169B2 (en) * 2003-02-27 2008-11-25 Abbott Laboratories Inc. Heterocyclic kinase inhibitors
TWI363756B (en) 2004-12-07 2012-05-11 Du Pont Method for preparing n-phenylpyrazole-1-carboxamides
DE102006032168A1 (de) * 2006-06-13 2007-12-20 Bayer Cropscience Ag Anthranilsäurediamid-Derivate mit heteroaromatischen Substituenten
RS53348B (en) * 2006-07-19 2014-10-31 E.I. Du Pont De Nemours And Company PROCEDURE FOR THE PREPARATION OF 3-SUBSTITUTED 2-AMINO-5-HALOBENZAMIDES
TWI395728B (zh) 2006-12-06 2013-05-11 Du Pont 製備２-胺基-５-氰基苯甲酸衍生物之方法
TWI415827B (zh) 2006-12-21 2013-11-21 Du Pont 製備２-胺基-５-氰基苯甲酸衍生物之方法
TWI430980B (zh) 2007-06-29 2014-03-21 Du Pont 製備２－胺基－5－氰基苯甲酸衍生物之方法
EP2205555B1 (en) 2007-11-08 2011-12-21 E. I. du Pont de Nemours and Company Process for preparing 2-amino-5-cyanobenzoic acid derivatives
TWI432421B (zh) 2007-12-19 2014-04-01 Du Pont 製備２－胺基－５－氰基苯甲酸衍生物之方法
TWI431000B (zh) 2008-03-05 2014-03-21 Du Pont 製備２－胺基－５－氰基苯甲酸衍生物之方法
JP5779102B2 (ja) * 2008-12-18 2015-09-16 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ 殺有害生物剤としてのテトラゾール置換アントラニルアミド
WO2011098408A2 (de) * 2010-02-09 2011-08-18 Bayer Cropscience Ag Hydrazin-substituierte anthranilsäurederivate
CN103068820A (zh) * 2010-06-15 2013-04-24 拜耳知识产权有限责任公司 新的邻位取代的芳基酰胺衍生物
CN103249729B (zh) * 2010-06-15 2017-04-05 拜耳知识产权有限责任公司 具有环状侧链的邻甲酰胺基苯甲酰胺衍生物
JP6199739B2 (ja) * 2010-06-15 2017-09-20 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ テトラゾール置換されたアントラニルアミド誘導体およびこれら誘導体の新規な結晶多形体の製造方法
CN103328434A (zh) 2011-01-28 2013-09-25 纳幕尔杜邦公司 制备2-氨基苯甲酰胺衍生物的方法
CN104245666B (zh) * 2012-02-07 2019-01-11 拜耳知识产权有限责任公司 取代的邻氨基苯甲酸衍生物的制备方法

Also Published As

Publication number Publication date
TWI644888B (zh) 2018-12-21
CN104245666A (zh) 2014-12-24
US20170217934A1 (en) 2017-08-03
MX2014009317A (es) 2014-11-12
US20160046607A1 (en) 2016-02-18
US20150011772A1 (en) 2015-01-08
JP2018027964A (ja) 2018-02-22
US9969717B2 (en) 2018-05-15
JP2015511229A (ja) 2015-04-16
BR112014019487A2 (pt) 2020-10-27
KR102032979B1 (ko) 2019-10-16
CN109970707A (zh) 2019-07-05
JP6438551B2 (ja) 2018-12-12
IL233945A0 (en) 2014-09-30
WO2013117601A1 (de) 2013-08-15
US9670182B2 (en) 2017-06-06
KR20140124810A (ko) 2014-10-27
EP2812310A1 (de) 2014-12-17
CN104245666B (zh) 2019-01-11
TW201336811A (zh) 2013-09-16

Similar Documents

Publication Publication Date Title
NZ603268A (en) Process for synthesizing oxidized lactam compounds
MX2015002616A (es) Sintesis de bis(fluorosulfonil)imida.
MX363730B (es) Procedimiento para la preparacion de derivados de acido antranilico sustituidos.
ECSP13012612A (es) Derivados de quinazolin-4-(3h)-ona utilizados como inhibidores de p13 cinasa
NZ707389A (en) Process for preparing bile acid derivatives
MX349771B (es) Procedimiento para preparar derivados de diamida de acido antranilico sustituida con tetrazol haciendo reaccionar benzoxazinonas con aminas.
MX363614B (es) Proceso para la preparacion integrada de 4-hidroxi-4-metiltetrahid ropiranos 2-sustituidos y de 4-metiltetrahidropiranos 2-sustituidos.
EA201500234A1 (ru) Способ получения бензоксазинонов
GEP20135960B (en) New method of synthesis of ivabradine and pharmaceutically acceptable acid-additive salts thereof
MX2014014138A (es) Procedimiento nuevo para la preparacion de acido 2-ciclopentil-6-metoxi-isonicotinico.
IN2014DN09053A (es)
JO2928B1 (en) A method for the preparation of ferroquine with amine by convergent reduction
MX2010003213A (es) Nuevo procedimiento de sintesis de la ivabradina y de sus sales de adicion a un acido farmaceuticamente aceptable.
MX337997B (es) Nuevo procedimiento de sintesis de la ivabradina y de sus sales de adicion a un acido farmaceuticamente aceptable.
MX350430B (es) Proceso para preparar compuestos acido 4-amino-5-bifenil-4-il-2-hi droximetil-2-metil-pentanoico.
MX2013004872A (es) Procesos para preparar un fenilciclohexano.
GB201104203D0 (en) Chemical process
TN2014000329A1 (en) Method for preparing compound by novel michael addition reaction using water or various acids as additive
IN2014DN03469A (es)
MY160047A (en) Process for the preparation and work-up of a reaction mixture containing triacetone amine
GB2523674A (en) Compounds as inhibitor of DNA double-strand break repair, methods and applications thereof
MX2013004193A (es) Procedimiento para la preparacion de derivados de acido 3-(6-amino-piridin-3-il)-2-acrilico.
MX361998B (es) Procedimiento de preparacion de derivados de acido 4-haloalquil-3-mercapto-2 sustituido-hidroxibenzoico.
IN2015DN02241A (es)
UA111329C2 (uk) Спосіб синтезу івабрадину і його адитивних солей з фармацевтично прийнятною кислотою

Legal Events

Date Code Title Description
FG Grant or registration