MX362905B - Tratamiento de combinacion. - Google Patents

Tratamiento de combinacion.

Info

Publication number
MX362905B
MX362905B MX2015011588A MX2015011588A MX362905B MX 362905 B MX362905 B MX 362905B MX 2015011588 A MX2015011588 A MX 2015011588A MX 2015011588 A MX2015011588 A MX 2015011588A MX 362905 B MX362905 B MX 362905B
Authority
MX
Mexico
Prior art keywords
taxane
pharmaceutically acceptable
acceptable salt
compound
treatment
Prior art date
Application number
MX2015011588A
Other languages
English (en)
Other versions
MX2015011588A (es
Inventor
Robert Davies Barry
Joy Hancox Ursula
Chiara Cosulich Sabina
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of MX2015011588A publication Critical patent/MX2015011588A/es
Publication of MX362905B publication Critical patent/MX362905B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)

Abstract

La presente invención se refiere al uso de combinaciones que comprenden 8-[(1R)-1-(3,5-difluorofenilamino)etil]-N,N-dimetil-2-m orfolino-4-oxo-4H-cromeno-6-carboxamida o una sal farmacéuticamente aceptable de la misma y un taxano en el tratamiento o profilaxis de cáncer; composiciones farmacéuticas que comprenden el Compuesto [I] (o una sal farmacéuticamente aceptable del mismo) y un taxano; kits que comprenden el Compuesto [I] o una sal farmacéuticamente aceptable del mismo y un taxano, opcionalmente con instrucciones para su uso; y métodos de tratamiento que comprenden la administración simultánea, secuencial o separada del Compuesto [I] o una sal farmacéuticamente aceptable del mismo y un taxano a un animal de sangre caliente, tal como el hombre.
MX2015011588A 2013-03-04 2014-03-03 Tratamiento de combinacion. MX362905B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361772079P 2013-03-04 2013-03-04
US201361771974P 2013-03-04 2013-03-04
PCT/GB2014/050618 WO2014135851A1 (en) 2013-03-04 2014-03-03 Combination treatment

Publications (2)

Publication Number Publication Date
MX2015011588A MX2015011588A (es) 2015-12-09
MX362905B true MX362905B (es) 2019-02-25

Family

ID=50288179

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015011588A MX362905B (es) 2013-03-04 2014-03-03 Tratamiento de combinacion.

Country Status (13)

Country Link
US (1) US9763950B2 (es)
EP (1) EP2964217B1 (es)
JP (1) JP6546098B2 (es)
KR (1) KR102222346B1 (es)
CN (1) CN105142629B (es)
AU (1) AU2014224445C1 (es)
BR (1) BR112015019524A8 (es)
CA (1) CA2900136C (es)
ES (1) ES2754034T3 (es)
HK (1) HK1216391A1 (es)
MX (1) MX362905B (es)
RU (1) RU2666999C2 (es)
WO (1) WO2014135851A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201815787A (zh) 2016-09-23 2018-05-01 美商基利科學股份有限公司 磷脂醯肌醇3-激酶抑制劑
TW201825465A (zh) 2016-09-23 2018-07-16 美商基利科學股份有限公司 磷脂醯肌醇3-激酶抑制劑
TW201813963A (zh) 2016-09-23 2018-04-16 美商基利科學股份有限公司 磷脂醯肌醇3-激酶抑制劑
JP7372252B2 (ja) * 2018-03-16 2023-10-31 ディーエフビー ソリア リミテッド ライアビリティ カンパニー タキサンのナノ粒子を用いる子宮頸部上皮内腫瘍（ｃｉｎ）および子宮頸癌の処置のための局所療法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04502322A (ja) 1988-12-21 1992-04-23 ジ・アップジョン・カンパニー 抗アテローム性動脈硬化症性および抗血栓性１―ベンゾピラン―４―オン類および２―アミノ―１，３―ベンゾオキサジン―４―オン類
US6749868B1 (en) 1993-02-22 2004-06-15 American Bioscience, Inc. Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
US5439686A (en) 1993-02-22 1995-08-08 Vivorx Pharmaceuticals, Inc. Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor
PT1023050E (pt) 1997-06-27 2013-12-04 Abraxis Bioscience Llc Novas formulações de agentes farmacológicos, métodos para a sua preparação e métodos para a sua utilização
US6395300B1 (en) 1999-05-27 2002-05-28 Acusphere, Inc. Porous drug matrices and methods of manufacture thereof
RU2284818C2 (ru) * 2001-05-10 2006-10-10 Анормед, Инк. Комбинированная химиотерапия
JP4646626B2 (ja) 2002-08-16 2011-03-09 アストラゼネカ アクチボラグ ホスホイノシチド３−キナーゼβの阻害
CA2546920A1 (en) 2003-12-09 2005-06-23 Joel Moss Methods for suppressing an immune response or treating a proliferative disorder
CN101291658B (zh) 2005-08-31 2014-04-16 阿布拉科斯生物科学有限公司 用于制备稳定性增加的水难溶性药物的组合物和方法
RU2433818C2 (ru) 2005-08-31 2011-11-20 АБРАКСИС БАЙОСАЙЕНС, ЭлЭлСи Композиции, включающие слаборастворимые в воде фармацевтические вещества и противомикробные вещества
WO2008064244A2 (en) 2006-11-20 2008-05-29 The Trustees Of Columbia University In The City Of New York Phosphoinositide modulation for the treatment of neurodegenerative diseases
RU2438664C2 (ru) * 2007-05-15 2012-01-10 Пирамал Лайф Сайнсиз Лимитед Синергическая фармацевтическая комбинация для лечения рака
US8399460B2 (en) * 2009-10-27 2013-03-19 Astrazeneca Ab Chromenone derivatives
KR101851820B1 (ko) * 2011-04-01 2018-06-04 아스트라제네카 아베 치료적 요법

Also Published As

Publication number Publication date
WO2014135851A1 (en) 2014-09-12
RU2666999C2 (ru) 2018-09-13
KR20150122145A (ko) 2015-10-30
AU2014224445C1 (en) 2017-07-27
US20160022690A1 (en) 2016-01-28
MX2015011588A (es) 2015-12-09
AU2014224445A1 (en) 2015-08-27
EP2964217A1 (en) 2016-01-13
RU2015139515A (ru) 2017-04-10
AU2014224445B2 (en) 2017-02-02
CN105142629B (zh) 2018-11-23
CA2900136C (en) 2021-05-04
KR102222346B1 (ko) 2021-03-02
CA2900136A1 (en) 2014-09-12
US9763950B2 (en) 2017-09-19
CN105142629A (zh) 2015-12-09
EP2964217B1 (en) 2019-08-28
BR112015019524A2 (pt) 2017-07-18
HK1216391A1 (zh) 2016-11-11
JP2016510060A (ja) 2016-04-04
JP6546098B2 (ja) 2019-07-17
ES2754034T3 (es) 2020-04-15
BR112015019524A8 (pt) 2019-11-19

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