MX362089B - Nanopartículas que comprenden materiales metálicos y óxido de hafnio, preparación y usos de los mismos. - Google Patents
Nanopartículas que comprenden materiales metálicos y óxido de hafnio, preparación y usos de los mismos.Info
- Publication number
- MX362089B MX362089B MX2014007131A MX2014007131A MX362089B MX 362089 B MX362089 B MX 362089B MX 2014007131 A MX2014007131 A MX 2014007131A MX 2014007131 A MX2014007131 A MX 2014007131A MX 362089 B MX362089 B MX 362089B
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- Prior art keywords
- nanoparticles
- metallic
- hafnium oxide
- preparation
- relates
- Prior art date
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5115—Inorganic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/242—Gold; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/244—Lanthanides; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0052—Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1241—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
- A61K51/1244—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins microparticles or nanoparticles, e.g. polymeric nanoparticles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Nanotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dispersion Chemistry (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
- Powder Metallurgy (AREA)
Abstract
La presente invención se relaciona con nanopartículas novedosas las cuales se pueden utilizar ventajosamente en el sector salud como diagnóstico y/o agentes terapéuticos. Las nanopartículas de la invención comprenden un material metálico al menos parcialmente recubierto con un material de óxido de hafnio o incorporado en el mismo. Cuando se compararon a productos existentes, estas nanopartículas ofrecen un beneficio extraordinario sobre el cociente de riesgo. Específicamente, estas nanopartículas aumentan la eficiencia de nanopartículas metálicas conocidas. De hecho, conservan las propiedades intrínsecas del metal y son ahora además utilizables de manera segura en un mamífero, en particular en un ser humano. La invención también se relaciona a métodos para producir las nanopartículas, a composiciones que contienen las mismas, y al usos de las mismas.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161576437P | 2011-12-16 | 2011-12-16 | |
EP11193968 | 2011-12-16 | ||
PCT/EP2012/075731 WO2013087920A1 (en) | 2011-12-16 | 2012-12-17 | Nanoparticles comprising metallic and hafnium oxide materials, preparation and uses thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014007131A MX2014007131A (es) | 2014-09-04 |
MX362089B true MX362089B (es) | 2019-01-07 |
Family
ID=48611880
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014007131A MX362089B (es) | 2011-12-16 | 2012-12-17 | Nanopartículas que comprenden materiales metálicos y óxido de hafnio, preparación y usos de los mismos. |
Country Status (16)
Country | Link |
---|---|
US (1) | US10945965B2 (es) |
EP (1) | EP2790682B1 (es) |
JP (1) | JP6042450B2 (es) |
KR (1) | KR102025743B1 (es) |
CN (1) | CN104093401B (es) |
AU (1) | AU2012351537B2 (es) |
BR (1) | BR112014014412A2 (es) |
CA (1) | CA2857260C (es) |
EA (1) | EA029635B1 (es) |
HK (1) | HK1203353A1 (es) |
IL (1) | IL233035B (es) |
MA (1) | MA35851B1 (es) |
MX (1) | MX362089B (es) |
PL (1) | PL2790682T3 (es) |
SG (1) | SG11201403096VA (es) |
WO (1) | WO2013087920A1 (es) |
Families Citing this family (16)
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EP2729180B1 (en) | 2011-07-08 | 2019-01-23 | The University of North Carolina At Chapel Hill | Metal bisphosphonate nanoparticles for anti-cancer therapy and imaging and for treating bone disorders |
EA029635B1 (ru) | 2011-12-16 | 2018-04-30 | Нанобиотикс | Применение наночастицы, включающей металлический материал, покрытый материалом оксида гафния, в онкологии и композиция, ее содержащая |
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US10806694B2 (en) * | 2014-10-14 | 2020-10-20 | The University Of Chicago | Nanoparticles for photodynamic therapy, X-ray induced photodynamic therapy, radiotherapy, radiodynamic therapy, chemotherapy, immunotherapy, and any combination thereof |
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EP3638367A4 (en) | 2017-08-02 | 2021-07-21 | The University of Chicago | NANOMETRIC ORGANOMETALLIC AND NANOPLAQUE ORGANOMETALLIC LAYERS FOR X-RAY INDUCED PHOTODYNAMIC THERAPY, RADIOTHERAPY, RADIODYNAMIC THERAPY, CHEMOTHERAPY, IMMUNOTHERAPY, AND ANY COMBINATION OF THESE |
JP7116563B2 (ja) * | 2018-03-16 | 2022-08-10 | 株式会社日本触媒 | 複合粒子 |
CN109010828B (zh) * | 2018-10-12 | 2020-10-20 | 中国科学院高能物理研究所 | 一种二硫化钼/二氧化铪的复合纳米材料、其制备方法及用途 |
CN112675305B (zh) * | 2021-01-22 | 2023-05-23 | 中国科学院深圳先进技术研究院 | 用于肿瘤治疗的双亲性分子自组装纳米药物及制备方法和用途 |
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WO2014202723A1 (en) | 2013-06-20 | 2014-12-24 | Nanobiotix | Compositions and methods for use in medical diagnosis |
EP2886128A1 (en) | 2013-12-20 | 2015-06-24 | Nanobiotix | Pharmaceutical composition comprising nanoparticles, preparation and uses thereof |
-
2012
- 2012-12-17 EA EA201491199A patent/EA029635B1/ru not_active IP Right Cessation
- 2012-12-17 CN CN201280062223.XA patent/CN104093401B/zh active Active
- 2012-12-17 AU AU2012351537A patent/AU2012351537B2/en active Active
- 2012-12-17 JP JP2014546562A patent/JP6042450B2/ja active Active
- 2012-12-17 KR KR1020147019571A patent/KR102025743B1/ko active IP Right Grant
- 2012-12-17 PL PL12806026T patent/PL2790682T3/pl unknown
- 2012-12-17 MX MX2014007131A patent/MX362089B/es active IP Right Grant
- 2012-12-17 BR BR112014014412A patent/BR112014014412A2/pt not_active Application Discontinuation
- 2012-12-17 WO PCT/EP2012/075731 patent/WO2013087920A1/en active Application Filing
- 2012-12-17 US US14/364,859 patent/US10945965B2/en active Active
- 2012-12-17 CA CA2857260A patent/CA2857260C/en active Active
- 2012-12-17 SG SG11201403096VA patent/SG11201403096VA/en unknown
- 2012-12-17 EP EP12806026.6A patent/EP2790682B1/en active Active
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2014
- 2014-06-09 IL IL233035A patent/IL233035B/en active IP Right Grant
- 2014-07-09 MA MA37185A patent/MA35851B1/fr unknown
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2015
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Also Published As
Publication number | Publication date |
---|---|
CA2857260C (en) | 2019-10-15 |
US10945965B2 (en) | 2021-03-16 |
CN104093401A (zh) | 2014-10-08 |
MA35851B1 (fr) | 2014-12-01 |
KR20140108685A (ko) | 2014-09-12 |
NZ625848A (en) | 2015-04-24 |
CA2857260A1 (en) | 2013-06-20 |
EA029635B1 (ru) | 2018-04-30 |
EP2790682B1 (en) | 2019-03-20 |
WO2013087920A1 (en) | 2013-06-20 |
JP6042450B2 (ja) | 2016-12-14 |
PL2790682T3 (pl) | 2019-08-30 |
AU2012351537B2 (en) | 2017-03-02 |
SG11201403096VA (en) | 2014-07-30 |
IL233035B (en) | 2018-02-28 |
AU2012351537A1 (en) | 2014-07-24 |
EA201491199A1 (ru) | 2014-11-28 |
KR102025743B1 (ko) | 2019-09-26 |
IL233035A0 (en) | 2014-07-31 |
US20140335015A1 (en) | 2014-11-13 |
MX2014007131A (es) | 2014-09-04 |
CN104093401B (zh) | 2018-06-29 |
JP2015509079A (ja) | 2015-03-26 |
BR112014014412A2 (pt) | 2017-06-13 |
EP2790682A1 (en) | 2014-10-22 |
HK1203353A1 (en) | 2015-10-30 |
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