MX358730B - Metodos para predecir y monitorear cicatrizacion de la mucosa. - Google Patents
Metodos para predecir y monitorear cicatrizacion de la mucosa.Info
- Publication number
- MX358730B MX358730B MX2015004272A MX2015004272A MX358730B MX 358730 B MX358730 B MX 358730B MX 2015004272 A MX2015004272 A MX 2015004272A MX 2015004272 A MX2015004272 A MX 2015004272A MX 358730 B MX358730 B MX 358730B
- Authority
- MX
- Mexico
- Prior art keywords
- mucosal healing
- predicting
- monitoring
- methods
- present
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/06—Gastro-intestinal diseases
- G01N2800/065—Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Medical Informatics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Databases & Information Systems (AREA)
- Data Mining & Analysis (AREA)
- Epidemiology (AREA)
- Primary Health Care (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención se refiere a métodos para predecir la probabilidad de cicatrización de la mucosa en un individuo con una enfermedad tal como enfermedad inflamatoria del intestino (IBD). Además, la presente invención proporciona métodos para monitorear la progresión de la cicatrización de la mucosa en un individuo con una enfermedad tal como IBD. Información sobre el estado de cicatrización de la mucosa derivada del uso de la presente invención también puede ayudar en la organización de la terapia y/o el monitoreo de la eficacia de un fármaco inhibidor de anti-TNFa.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261710491P | 2012-10-05 | 2012-10-05 | |
US201361824959P | 2013-05-17 | 2013-05-17 | |
PCT/IB2013/059077 WO2014054013A1 (en) | 2012-10-05 | 2013-10-02 | Methods for predicting and monitoring mucosal healing |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2015004272A MX2015004272A (es) | 2015-08-14 |
MX358730B true MX358730B (es) | 2018-09-03 |
Family
ID=49447587
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015004272A MX358730B (es) | 2012-10-05 | 2013-10-02 | Metodos para predecir y monitorear cicatrizacion de la mucosa. |
Country Status (11)
Country | Link |
---|---|
US (1) | US20150355195A1 (es) |
EP (3) | EP3217179B9 (es) |
JP (1) | JP2015532425A (es) |
CN (1) | CN104838270A (es) |
AU (2) | AU2013326070A1 (es) |
CA (1) | CA2887035A1 (es) |
ES (2) | ES2771127T3 (es) |
HK (1) | HK1213051A1 (es) |
MX (1) | MX358730B (es) |
SG (1) | SG11201502646RA (es) |
WO (1) | WO2014054013A1 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX362132B (es) | 2011-05-10 | 2019-01-07 | Nestec Sa | Metodos para perfilado de actividad de enfermedad para manejo de terapia personalizado. |
MX2017004816A (es) * | 2014-10-20 | 2017-08-02 | Nestec Sa | Métodos para predecir resultados clínicos en sujetos afectados con colitis ulcerosa. |
EP3212198B1 (en) | 2014-10-29 | 2020-12-23 | Glycom A/S | Synthetic composition and method for promoting mucosal healing |
GB201501612D0 (en) * | 2015-01-30 | 2015-03-18 | Univ Birmingham | Assay |
GB201611738D0 (en) * | 2016-07-05 | 2016-08-17 | Cambridge Entpr Ltd | Biomarkers for inflammatory bowel disease |
US11162943B2 (en) | 2017-05-31 | 2021-11-02 | Prometheus Biosciences Inc. | Methods for assessing mucosal healing in Crohn's disease patients |
CN110646620A (zh) * | 2019-09-29 | 2020-01-03 | 湖北新纵科病毒疾病工程技术有限公司 | 一种同时检测四项炎症标志物的方法及其试剂盒 |
CN111477325A (zh) * | 2020-04-09 | 2020-07-31 | 赣南师范大学 | 基于粒子群优化算法对引发肠道溃疡疾病进行鉴别的方法 |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5830675A (en) | 1993-03-10 | 1998-11-03 | Cedars-Sinai Medical Center | Methods for selectively detecting perinuclear anti-neutrophil cytoplasmic antibody of ulcerative colitis, primary sclerosing cholangitis, or type 1 autoimmune hepatitis |
ATE193601T1 (de) | 1993-03-10 | 2000-06-15 | Cedars Sinai Medical Center | Verfahren zum selektiven nachweis von perinuklearen anti-neutrophilen cytoplasmischen antikörpern bei ulzerativen kolitis oder primärer sclerotischer cholangitis |
US6218129B1 (en) | 1998-05-15 | 2001-04-17 | Prometheus Laboratories, Inc. | Inflammatory bowel disease first step assay system |
US6406862B1 (en) | 1998-10-06 | 2002-06-18 | The United States Of America As Represented By The Secretary Of The Army | Dip-stick assay for C-reactive protein |
FR2802536B1 (fr) | 1999-11-23 | 2003-06-13 | Chru Lille | Oligomannosides de synthese, leur preparation et leur utilisation a la detection d'anticorps et a la prevention d'infections |
US6838250B2 (en) | 2000-03-31 | 2005-01-04 | Ortho-Clinical Diagnostics, Inc. | Immunoassay for C-reactive protein |
US7531352B2 (en) * | 2000-04-20 | 2009-05-12 | The United States Of America As Represented By The Department Of Health And Human Services | Inducible plasmid vector encoding TGF-β and use thereof |
US7138237B1 (en) | 2000-05-19 | 2006-11-21 | Cedars-Sinai Medical Center | Diagnosis, prevention and treatment of Crohn's disease using the OmpC antigen |
ES2405790T3 (es) | 2001-12-17 | 2013-06-03 | Corixa Corporation | Composiciones y métodos para la terapia y el diagnóstico de enfermedad inflamatoria del intestino |
US20040197304A1 (en) * | 2003-04-01 | 2004-10-07 | The Procter & Gamble Company And Alimentary Health, Ltd. | Methods of determining efficacy of treatments of inflammatory diseases of the bowel |
US7439019B2 (en) | 2003-11-03 | 2008-10-21 | Duke University | Methods of identifying individuals at risk of perioperative bleeding, renal dysfunction |
WO2006012472A1 (en) | 2004-07-21 | 2006-02-02 | Qualyst, Inc. | Apparatus, kits and methods for evaluating binding interactions, for detecting and quantifying binding molecules, and for sample preparation |
US7868139B2 (en) | 2006-01-24 | 2011-01-11 | Uab Research Foundation | Compositions and methods for the identification and treatment of immune-mediated inflammatory diseases |
NZ575827A (en) | 2006-09-21 | 2012-02-24 | Prometheus Lab Inc | Antibody-based arrays for detecting multiple signal transducers in rare circulating cells |
CN101802618B (zh) | 2007-07-13 | 2015-02-25 | 雀巢产品技术援助有限公司 | 利用基于抗体的阵列选择肺癌治疗药物 |
NZ617520A (en) | 2008-02-25 | 2015-05-29 | Nestec Sa | Drug selection for breast cancer therapy using antibody-based arrays |
CN107041948A (zh) * | 2009-01-21 | 2017-08-15 | 北京三有利科技发展有限公司 | 细胞生长因子治疗溃疡性疾病和肺纤维化疾病的应用 |
NZ596468A (en) | 2009-05-14 | 2013-11-29 | Nestec Sa | Biomarkers for determining sensitivity of breast cancer cells to her2-targeted therapy |
AU2010273319B2 (en) | 2009-07-15 | 2015-01-22 | Nestec S.A. | Drug selection for gastric cancer therapy using antibody-based arrays |
EP2491385B1 (en) | 2009-10-20 | 2017-05-10 | DiaTech Holdings, Inc. | Proximity-mediated assays for detecting oncogenic fusion proteins |
NZ621655A (en) | 2009-10-26 | 2015-08-28 | Nestec Sa | Assays for the detection of anti-tnf drugs and autoantibodies |
AU2010324735A1 (en) * | 2009-11-25 | 2012-07-12 | Nestec S.A. | Novel genomic biomarkers for irritable bowel syndrome diagnosis |
CA2801575A1 (en) * | 2010-06-04 | 2011-12-08 | Prometheus Laboratories Inc. | Methods for improving inflammatory bowel disease diagnosis |
EP2630495B1 (en) | 2010-10-18 | 2017-02-08 | Nestec S.A. | Methods for determining anti-drug antibody isotypes |
WO2012088337A1 (en) | 2010-12-23 | 2012-06-28 | Prometheus Laboratories Inc. | Drug selection for malignant cancer therapy using antibody-based arrays |
KR20140008397A (ko) | 2011-02-17 | 2014-01-21 | 네스텍 소시에테아노님 | 항-TNFα 약물에 대한 자가항체 검출을 위한 검정법 |
ES2734673T3 (es) | 2011-03-02 | 2019-12-11 | Nestle Sa | Predicción de la sensibilidad farmacológica de tumores de pulmón basándose en identificaciones moleculares y genéticas |
AU2012278802B2 (en) | 2011-07-06 | 2015-11-26 | Société des Produits Nestlé S.A. | Assays for detecting neutralizing autoantibodies to biologic therapy with TNF alpha |
KR101851425B1 (ko) | 2011-09-02 | 2018-04-23 | 네스텍 소시에테아노님 | 치료 효능 결정을 위한 신호 경로 단백질의 프로파일링 |
-
2013
- 2013-10-02 JP JP2015535153A patent/JP2015532425A/ja active Pending
- 2013-10-02 SG SG11201502646RA patent/SG11201502646RA/en unknown
- 2013-10-02 CA CA2887035A patent/CA2887035A1/en not_active Abandoned
- 2013-10-02 WO PCT/IB2013/059077 patent/WO2014054013A1/en active Application Filing
- 2013-10-02 AU AU2013326070A patent/AU2013326070A1/en not_active Abandoned
- 2013-10-02 ES ES17167637T patent/ES2771127T3/es active Active
- 2013-10-02 CN CN201380063566.2A patent/CN104838270A/zh active Pending
- 2013-10-02 MX MX2015004272A patent/MX358730B/es active IP Right Grant
- 2013-10-02 EP EP17167637.2A patent/EP3217179B9/en active Active
- 2013-10-02 EP EP13779638.9A patent/EP2904405B1/en not_active Not-in-force
- 2013-10-02 EP EP19212960.9A patent/EP3640645A1/en not_active Withdrawn
- 2013-10-02 ES ES13779638.9T patent/ES2638971T3/es active Active
-
2015
- 2015-04-03 US US14/678,455 patent/US20150355195A1/en not_active Abandoned
-
2016
- 2016-01-26 HK HK16100852.9A patent/HK1213051A1/zh unknown
-
2019
- 2019-06-19 AU AU2019204276A patent/AU2019204276A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP3217179B9 (en) | 2020-06-10 |
SG11201502646RA (en) | 2015-05-28 |
MX2015004272A (es) | 2015-08-14 |
WO2014054013A1 (en) | 2014-04-10 |
EP3640645A1 (en) | 2020-04-22 |
EP2904405B1 (en) | 2017-05-31 |
ES2638971T3 (es) | 2017-10-24 |
JP2015532425A (ja) | 2015-11-09 |
EP3217179B1 (en) | 2020-01-08 |
CA2887035A1 (en) | 2014-04-10 |
EP3217179A1 (en) | 2017-09-13 |
US20150355195A1 (en) | 2015-12-10 |
HK1213051A1 (zh) | 2016-06-24 |
CN104838270A (zh) | 2015-08-12 |
AU2013326070A1 (en) | 2015-04-23 |
ES2771127T3 (es) | 2020-07-06 |
AU2019204276A1 (en) | 2019-07-04 |
EP2904405A1 (en) | 2015-08-12 |
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Legal Events
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