MX357440B - Trombospondina 1 (tsp-1), trombospondina 2 (tsp-2), receptor de interleucina 17b (il-17br) y factor de crecimiento tipo factor de crecimiento epidermico de union a heparina (hb-egf) asociados con actividades de celulas madre y aplicaciones de los mismos. - Google Patents
Trombospondina 1 (tsp-1), trombospondina 2 (tsp-2), receptor de interleucina 17b (il-17br) y factor de crecimiento tipo factor de crecimiento epidermico de union a heparina (hb-egf) asociados con actividades de celulas madre y aplicaciones de los mismos.Info
- Publication number
- MX357440B MX357440B MX2014009492A MX2014009492A MX357440B MX 357440 B MX357440 B MX 357440B MX 2014009492 A MX2014009492 A MX 2014009492A MX 2014009492 A MX2014009492 A MX 2014009492A MX 357440 B MX357440 B MX 357440B
- Authority
- MX
- Mexico
- Prior art keywords
- tsp
- applications
- stem cell
- cell activities
- egf associated
- Prior art date
Links
- 102000018710 Heparin-binding EGF-like Growth Factor Human genes 0.000 title abstract 2
- 101800001649 Heparin-binding EGF-like growth factor Proteins 0.000 title abstract 2
- 210000000130 stem cell Anatomy 0.000 title abstract 2
- 101100202924 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) tsp-2 gene Proteins 0.000 title 1
- 101100208237 Bos taurus THBS2 gene Proteins 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0655—Chondrocytes; Cartilage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/44—Vessels; Vascular smooth muscle cells; Endothelial cells; Endothelial progenitor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
- C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/34—Sugars
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/36—Lipids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/15—Transforming growth factor beta (TGF-β)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/39—Steroid hormones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/998—Proteins not provided for elsewhere
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Cell Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Developmental Biology & Embryology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
La presente invención se refiere a una modalidad de ejemplo de la presente invención proporciona TSP-1, TSP-2, IL-17BR y HB-EGF asociados con actividades de células madre y aplicaciones de los mismos.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20090041753 | 2009-05-13 | ||
US18248409P | 2009-05-29 | 2009-05-29 | |
PCT/KR2010/003040 WO2010131917A2 (ko) | 2009-05-13 | 2010-05-13 | 줄기세포의 세포 활성과 연관된 tsp-1, tsp-2, il-17br 및 hb-egf 및 이들의 용도 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX357440B true MX357440B (es) | 2018-07-10 |
Family
ID=43085467
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014009492A MX357440B (es) | 2009-05-13 | 2010-05-13 | Trombospondina 1 (tsp-1), trombospondina 2 (tsp-2), receptor de interleucina 17b (il-17br) y factor de crecimiento tipo factor de crecimiento epidermico de union a heparina (hb-egf) asociados con actividades de celulas madre y aplicaciones de los mismos. |
MX2011011961A MX337823B (es) | 2009-05-13 | 2010-05-13 | Trombospondina 1 (tsp-1), trombospondina 2 (tsp-2), receptor de interleucina 17b (il-17br) y factor de crecimiento tipo factor de crecimiento epidermico de union a heparina (hb-egf) asociados con actividades de celulas madre y aplicaciones de los mismos. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2011011961A MX337823B (es) | 2009-05-13 | 2010-05-13 | Trombospondina 1 (tsp-1), trombospondina 2 (tsp-2), receptor de interleucina 17b (il-17br) y factor de crecimiento tipo factor de crecimiento epidermico de union a heparina (hb-egf) asociados con actividades de celulas madre y aplicaciones de los mismos. |
Country Status (10)
Country | Link |
---|---|
EP (2) | EP2752483B1 (es) |
JP (2) | JP5972163B2 (es) |
KR (2) | KR101211930B1 (es) |
CN (1) | CN102482645B (es) |
CA (1) | CA2761610C (es) |
ES (1) | ES2559235T3 (es) |
MX (2) | MX357440B (es) |
MY (1) | MY153917A (es) |
SG (1) | SG176037A1 (es) |
WO (1) | WO2010131917A2 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9040298B2 (en) | 2009-05-29 | 2015-05-26 | Medipost Co., Ltd. | Method of selecting stem cells having high chondrogenic differentiation capability |
WO2013063518A1 (en) * | 2011-10-28 | 2013-05-02 | Tufts University | A 3d culture system for culturing cells in synovial fluid, cells cultured in synovial fluid and their use |
KR101667001B1 (ko) * | 2013-08-12 | 2016-10-17 | 한국생명공학연구원 | 줄기세포 배양액에서 탐지 가능한 지방유래 줄기세포의 증식 및 치료능력 탐지용 마커 및 이의 용도 |
WO2016006712A1 (ja) * | 2014-07-11 | 2016-01-14 | 国立研究開発法人産業技術総合研究所 | 細胞分化ポテンシャル判別法 |
US20160158293A1 (en) * | 2014-12-05 | 2016-06-09 | Janssen Biotech, Inc. | Treatment of Ocular Conditions Using Progenitor Cells |
CN111033258B (zh) * | 2017-06-30 | 2023-09-05 | 可隆生命科学株式会社 | 用于评价细胞治疗产品的有效性的方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020119921A1 (en) * | 1999-03-31 | 2002-08-29 | Michael Streit | Thrombospondin-2 and uses thereof |
US20020022592A1 (en) * | 1999-03-31 | 2002-02-21 | Michael Detmar | Delivery of thrombospondin from implantable tissue matrices |
DE60234163D1 (de) * | 2001-01-05 | 2009-12-10 | Viromed Ltd | Zusammensetzungen zur gentherapie rheumatoider arthritis, die ein gen, das für ein anti-angiogenes protein oder teile davon kodiert, enthalten |
US7459307B2 (en) * | 2001-08-14 | 2008-12-02 | Medipost Co., Ltd | Composition for treatment of articular cartilage damage |
AU2003207399A1 (en) * | 2002-02-19 | 2003-09-09 | Medipost Co., Ltd. | Isolation and culture-expansion methods of mesenchymal stem/progenitor cells from umbilical cord blood, and differentiation method of umbilical cord blood-derived mesenchymal stem/progenitor cells into various mesenchymal tissues |
CA2530421C (en) * | 2003-06-27 | 2015-04-21 | Ethicon, Incorporated | Repair and regeneration of ocular tissue using postpartum-derived cells |
US8119397B2 (en) * | 2004-03-31 | 2012-02-21 | Two Cells Co., Ltd. | Therapeutic agents and therapeutic methods for treating injured tissue |
US20090162436A1 (en) * | 2006-06-14 | 2009-06-25 | Carson Daniel D | Compositions and methods for repair of tissues |
KR100816395B1 (ko) * | 2006-09-21 | 2008-03-27 | (주)필미아젠 | 세포 유래 세포외기질막의 제조방법 |
JP2008289476A (ja) * | 2007-04-27 | 2008-12-04 | Hiroshima Univ | 骨分化状態を測定する組成物および骨分化を調節する組成物 |
-
2010
- 2010-05-13 EP EP13189750.6A patent/EP2752483B1/en active Active
- 2010-05-13 ES ES10775119.0T patent/ES2559235T3/es active Active
- 2010-05-13 MX MX2014009492A patent/MX357440B/es unknown
- 2010-05-13 WO PCT/KR2010/003040 patent/WO2010131917A2/ko active Application Filing
- 2010-05-13 EP EP10775119.0A patent/EP2431460B1/en active Active
- 2010-05-13 MY MYPI2011005391A patent/MY153917A/en unknown
- 2010-05-13 KR KR1020100045128A patent/KR101211930B1/ko active IP Right Grant
- 2010-05-13 JP JP2012510753A patent/JP5972163B2/ja active Active
- 2010-05-13 CN CN201080020829.8A patent/CN102482645B/zh active Active
- 2010-05-13 MX MX2011011961A patent/MX337823B/es active IP Right Grant
- 2010-05-13 SG SG2011083409A patent/SG176037A1/en unknown
- 2010-05-13 CA CA2761610A patent/CA2761610C/en active Active
-
2011
- 2011-11-22 KR KR1020110122410A patent/KR101596214B1/ko active IP Right Grant
-
2016
- 2016-03-28 JP JP2016063564A patent/JP6271623B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
CA2761610A1 (en) | 2010-11-18 |
KR101596214B1 (ko) | 2016-02-22 |
SG176037A1 (en) | 2011-12-29 |
EP2431460B1 (en) | 2015-10-14 |
EP2752483B1 (en) | 2018-01-17 |
KR20120002506A (ko) | 2012-01-05 |
KR20100122876A (ko) | 2010-11-23 |
EP2752483A1 (en) | 2014-07-09 |
CN102482645B (zh) | 2015-12-09 |
ES2559235T3 (es) | 2016-02-11 |
EP2431460A2 (en) | 2012-03-21 |
JP2016136159A (ja) | 2016-07-28 |
EP2431460A4 (en) | 2013-06-05 |
KR101211930B1 (ko) | 2012-12-13 |
MX337823B (es) | 2016-03-22 |
CN102482645A (zh) | 2012-05-30 |
JP5972163B2 (ja) | 2016-08-17 |
JP2012526549A (ja) | 2012-11-01 |
WO2010131917A3 (ko) | 2011-06-23 |
MY153917A (en) | 2015-04-15 |
JP6271623B2 (ja) | 2018-01-31 |
CA2761610C (en) | 2020-12-29 |
MX2011011961A (es) | 2011-12-06 |
WO2010131917A2 (ko) | 2010-11-18 |
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