MX346973B - Anticuerpos especificos de tumores y usos para los mismos. - Google Patents

Anticuerpos especificos de tumores y usos para los mismos.

Info

Publication number
MX346973B
MX346973B MX2013003825A MX2013003825A MX346973B MX 346973 B MX346973 B MX 346973B MX 2013003825 A MX2013003825 A MX 2013003825A MX 2013003825 A MX2013003825 A MX 2013003825A MX 346973 B MX346973 B MX 346973B
Authority
MX
Mexico
Prior art keywords
methods
same
specific antibodies
tumor specific
uses therefor
Prior art date
Application number
MX2013003825A
Other languages
English (en)
Other versions
MX2013003825A (es
Inventor
Mukherjee Pinku
Original Assignee
Univ North Carolina Charlotte
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ North Carolina Charlotte filed Critical Univ North Carolina Charlotte
Publication of MX2013003825A publication Critical patent/MX2013003825A/es
Publication of MX346973B publication Critical patent/MX346973B/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3076—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
    • C07K16/3092—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties against tumour-associated mucins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
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    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K—PEPTIDES
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    • C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • C07K—PEPTIDES
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Abstract

La presente invención se refiere a los anticuerpos aislados y los fragmentos y derivados de los mismos, los cuales se enlazan a los antígenos tumorales. También se proporcionan las composiciones y los agentes de distribución que incluyen los anticuerpos descritos y los fragmentos y derivados de los mismos; las células que producen los mismos; los métodos para producir los mismos; los métodos para utilizar los mismos para detectar, dirigirse a y/o tratar tumores y/o células metatásticas derivadas de los mismos y/o las células de la línea tumoral; y los métodos para predecir la recurrencia del cáncer en un sujeto.
MX2013003825A 2010-10-08 2011-05-25 Anticuerpos especificos de tumores y usos para los mismos. MX346973B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/924,952 US8518405B2 (en) 2009-10-08 2010-10-08 Tumor specific antibodies and uses therefor
PCT/US2011/037972 WO2012047317A2 (en) 2010-10-08 2011-05-25 Tumor specific antibodies and uses therefor

Publications (2)

Publication Number Publication Date
MX2013003825A MX2013003825A (es) 2013-09-02
MX346973B true MX346973B (es) 2017-04-07

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MX2013003825A MX346973B (es) 2010-10-08 2011-05-25 Anticuerpos especificos de tumores y usos para los mismos.

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US (5) US8518405B2 (es)
EP (1) EP2624866B1 (es)
JP (2) JP5886299B2 (es)
KR (1) KR101883280B1 (es)
CN (1) CN103492417B (es)
AU (1) AU2011312830B2 (es)
BR (1) BR112013008480A2 (es)
CA (1) CA2813814C (es)
DK (1) DK2624866T3 (es)
ES (1) ES2927050T3 (es)
IL (1) IL225545A0 (es)
MX (1) MX346973B (es)
RU (1) RU2595403C2 (es)
WO (1) WO2012047317A2 (es)

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US8518405B2 (en) * 2009-10-08 2013-08-27 The University Of North Carolina At Charlotte Tumor specific antibodies and uses therefor
US9845362B2 (en) 2010-10-08 2017-12-19 The University Of North Carolina At Charlotte Compositions comprising chimeric antigen receptors, T cells comprising the same, and methods of using the same
WO2014047278A1 (en) * 2012-09-20 2014-03-27 Viracor-Ibt Laboratories A method for determination of cellular immune response to therapeutic vaccines
US9416395B2 (en) * 2013-03-15 2016-08-16 City Of Hope Methods, compositions, and kits for detection of aspergillosis
US11554181B2 (en) 2014-09-05 2023-01-17 The University Of North Carolina At Charlotte Tumor specific antibody conjugates and uses therefor
WO2017120525A1 (en) * 2016-01-08 2017-07-13 The University Of North Carolina At Charlotte Compositions comprising chimeric antigen receptors, t cells comprising the same and methods of using the same
WO2016090434A1 (en) * 2014-12-12 2016-06-16 Commonwealth Scientific And Industrial Research Organisation Dislodgement and release of hsc using alpha 9 integrin antagonist and cxcr4 antagonist
US20180246104A1 (en) * 2015-08-18 2018-08-30 Agency For Science, Technology And Research Method for detecting circulating tumor cells and uses thereof
JP6861418B2 (ja) * 2015-09-02 2021-04-28 イッサム リサーチ デベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム リミテッド ヒトｔ細胞免疫グロブリン及びｉｔｉｍドメイン（ｔｉｇｉｔ）に特異的な抗体
SG11201811290VA (en) 2016-06-17 2019-01-30 Magenta Therapeutics Inc Compositions and methods for the depletion of cd117+cells
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