MX344248B - Metodos de purificacion de polipeptidos. - Google Patents

Metodos de purificacion de polipeptidos.

Info

Publication number
MX344248B
MX344248B MX2012013575A MX2012013575A MX344248B MX 344248 B MX344248 B MX 344248B MX 2012013575 A MX2012013575 A MX 2012013575A MX 2012013575 A MX2012013575 A MX 2012013575A MX 344248 B MX344248 B MX 344248B
Authority
MX
Mexico
Prior art keywords
methods
polypeptide
purifying
purifying polypeptides
polypeptides
Prior art date
Application number
MX2012013575A
Other languages
English (en)
Other versions
MX2012013575A (es
Inventor
Hui F Liu
Brian David Kelley
Deanna E Myers
Beth Mccooey
Krista Marie Petty
Original Assignee
Genentech Inc *
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45004368&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX344248(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc * filed Critical Genentech Inc *
Publication of MX2012013575A publication Critical patent/MX2012013575A/es
Publication of MX344248B publication Critical patent/MX344248B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
    • B01D15/361—Ion-exchange
    • B01D15/362—Cation-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3847—Multimodal interactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/165—Extraction; Separation; Purification by chromatography mixed-mode chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G01N2030/8831—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving peptides or proteins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La presente invención se refiere a un método para purificar un anticuerpo o una inmunoadhesina de una composición que comprende el anticuerpo o una inmunoadhesina y por lo menos un contaminante, en donde el método esta caracterizado porque comprende (I) o (ii): (i) etapas secuenciales de (a) carga de la composición sobre un material de intercambio catiónico a un densidad de carga mayor de alrededor de 150 g/l de material de intercambio catiónico y (b) carga de una composición recuperada del material de intercambio catiónico sobre el material de modo mezclado; o (ii) etapas secuenciales de (a) carga de la composición sobre un material de modo mezclado y (b) carga de una composición recuperada de un material de modo mezclado sobre un material de intercambio catiónico a una densidad de carga mayor de alrededor de 150 g/l de material de intercambio catiónico, en donde el material de intercambio catiónico son partículas de resina.
MX2012013575A 2010-05-25 2011-05-25 Metodos de purificacion de polipeptidos. MX344248B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34814310P 2010-05-25 2010-05-25
PCT/US2011/037977 WO2011150110A1 (en) 2010-05-25 2011-05-25 Methods of purifying polypeptides

Publications (2)

Publication Number Publication Date
MX2012013575A MX2012013575A (es) 2013-03-21
MX344248B true MX344248B (es) 2016-12-09

Family

ID=45004368

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2012013575A MX344248B (es) 2010-05-25 2011-05-25 Metodos de purificacion de polipeptidos.
MX2016016228A MX370828B (es) 2010-05-25 2011-05-25 Métodos de purificación de polipéptidos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2016016228A MX370828B (es) 2010-05-25 2011-05-25 Métodos de purificación de polipéptidos.

Country Status (21)

Country Link
US (4) US20130079272A1 (es)
EP (2) EP2575847B2 (es)
JP (3) JP5934190B2 (es)
KR (1) KR101976853B1 (es)
CN (2) CN107365346A (es)
AU (1) AU2011258254B2 (es)
BR (1) BR112012029904A2 (es)
CA (2) CA2799915C (es)
ES (1) ES2637613T5 (es)
HK (1) HK1246328A1 (es)
HR (1) HRP20171095T4 (es)
IL (2) IL223029A0 (es)
MX (2) MX344248B (es)
MY (1) MY161534A (es)
NZ (1) NZ603648A (es)
PL (1) PL2575847T5 (es)
RU (1) RU2594163C2 (es)
SG (2) SG10201710439UA (es)
SI (1) SI2575847T2 (es)
WO (1) WO2011150110A1 (es)
ZA (1) ZA201208673B (es)

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JP7458404B2 (ja) 2018-12-20 2024-03-29 アーマジェン・インコーポレイテッド イズロン酸－２－スルファターゼ免疫グロブリン融合タンパク質の精製
CN109765307B (zh) * 2018-12-24 2021-06-29 山东省科学院海洋仪器仪表研究所 一种水体中六氯环己烷的测量方法
CN111366547A (zh) * 2018-12-26 2020-07-03 贵州中烟工业有限责任公司 一种用连续流动法测定烟草或烟草制品中α-氨基氮的检测方法
EP3916001A4 (en) 2019-01-23 2022-10-19 Daiichi Sankyo Company, Limited ONE-STEP PROCEDURE FOR PURIFICATION OF ANTIBODIES USING ACTIVATED CARBON MATERIAL
TW202112799A (zh) * 2019-06-05 2021-04-01 美商建南德克公司 過載層析管柱之再生方法
US20220396598A1 (en) * 2019-10-14 2022-12-15 Pierce Biotechnology, Inc. Peptide purification formulations and methods
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CN112852876B (zh) * 2021-03-04 2022-11-29 西南大学 一种表达人表皮生长因子的家蚕丝腺重组表达载体及其制备方法和应用
JP2024514306A (ja) 2021-03-31 2024-04-01 エフ． ホフマン－ラ ロシュ アーゲー 混合モードクロマトグラフィーによる抗体の精製

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Also Published As

Publication number Publication date
KR20130086544A (ko) 2013-08-02
HRP20171095T1 (hr) 2017-10-06
SG10201710439UA (en) 2018-01-30
US20200399307A1 (en) 2020-12-24
EP2575847A4 (en) 2014-10-08
PL2575847T3 (pl) 2017-10-31
MX370828B (es) 2020-01-08
KR101976853B1 (ko) 2019-05-09
JP2013530156A (ja) 2013-07-25
AU2011258254A1 (en) 2013-01-10
JP6272941B2 (ja) 2018-01-31
CA3209878A1 (en) 2011-12-01
WO2011150110A1 (en) 2011-12-01
RU2594163C2 (ru) 2016-08-10
BR112012029904A2 (pt) 2017-08-08
EP3299380A1 (en) 2018-03-28
IL261147A (en) 2018-10-31
CA2799915A1 (en) 2011-12-01
CN102905718A (zh) 2013-01-30
SI2575847T2 (sl) 2022-08-31
EP2575847B1 (en) 2017-06-14
ES2637613T5 (es) 2022-07-20
HK1246328A1 (zh) 2018-09-07
EP2575847B2 (en) 2022-04-27
AU2011258254B2 (en) 2016-01-07
PL2575847T5 (pl) 2022-07-18
US20190300566A1 (en) 2019-10-03
EP2575847A1 (en) 2013-04-10
ES2637613T3 (es) 2017-10-13
MY161534A (en) 2017-04-28
HRP20171095T4 (hr) 2022-07-22
JP2016190851A (ja) 2016-11-10
RU2012156271A (ru) 2014-06-27
IL223029A0 (en) 2013-02-03
JP2018087192A (ja) 2018-06-07
CA2799915C (en) 2023-09-26
ZA201208673B (en) 2016-02-24
SG185737A1 (en) 2013-01-30
CN107365346A (zh) 2017-11-21
SI2575847T1 (sl) 2017-09-29
US20220064209A1 (en) 2022-03-03
MX2012013575A (es) 2013-03-21
JP5934190B2 (ja) 2016-06-15
US20130079272A1 (en) 2013-03-28
NZ603648A (en) 2014-12-24

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