MX342153B - Compuestos para el tratamiento y profilaxis de enfermedad por el virus sincitial respiratorio. - Google Patents

Compuestos para el tratamiento y profilaxis de enfermedad por el virus sincitial respiratorio.

Info

Publication number
MX342153B
MX342153B MX2014003701A MX2014003701A MX342153B MX 342153 B MX342153 B MX 342153B MX 2014003701 A MX2014003701 A MX 2014003701A MX 2014003701 A MX2014003701 A MX 2014003701A MX 342153 B MX342153 B MX 342153B
Authority
MX
Mexico
Prior art keywords
prophylaxis
compounds
treatment
respiratory syncytial
syncytial virus
Prior art date
Application number
MX2014003701A
Other languages
English (en)
Other versions
MX2014003701A (es
Inventor
Liang Chungen
Wang Lisha
Yun Hongying
Zheng Xiufang
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MX2014003701A publication Critical patent/MX2014003701A/es
Publication of MX342153B publication Critical patent/MX342153B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Abstract

Se describe un compuesto de fórmula (I) (ver fórmula) también como una sal aceptable farmacéuticamente del mismo, en donde R1, R2 y X son como se definen en la descripción y en las reivindicaciones, que pueden ser usadas como medicamento.
MX2014003701A 2011-10-11 2012-10-08 Compuestos para el tratamiento y profilaxis de enfermedad por el virus sincitial respiratorio. MX342153B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2011080627 2011-10-11
PCT/EP2012/069813 WO2013053658A1 (en) 2011-10-11 2012-10-08 Compounds for the treatment and prophylaxis of respiratory syncytial virus disease

Publications (2)

Publication Number Publication Date
MX2014003701A MX2014003701A (es) 2015-04-14
MX342153B true MX342153B (es) 2016-09-15

Family

ID=47018191

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014003701A MX342153B (es) 2011-10-11 2012-10-08 Compuestos para el tratamiento y profilaxis de enfermedad por el virus sincitial respiratorio.

Country Status (11)

Country Link
US (1) US8604019B2 (es)
EP (1) EP2766370B1 (es)
JP (1) JP2014530225A (es)
KR (1) KR20140088555A (es)
BR (1) BR112014008783A2 (es)
CA (1) CA2847071A1 (es)
ES (1) ES2593059T3 (es)
HK (1) HK1197058A1 (es)
MX (1) MX342153B (es)
RU (1) RU2014118330A (es)
WO (1) WO2013053658A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040175384A1 (en) * 2003-12-12 2004-09-09 Mohapatra Shyam S. Protein kinase C as a target for the treatment of respiratory syncytial virus
US10184942B2 (en) 2011-03-17 2019-01-22 University Of South Florida Natriuretic peptide receptor as a biomarker for diagnosis and prognosis of cancer
UA123854C2 (uk) 2013-08-21 2021-06-16 Аліос Біофарма, Інк. Противірусні сполуки
AR099134A1 (es) 2014-01-24 2016-06-29 Hoffmann La Roche Procedimiento para la preparación de n-[(3-aminooxetán-3-il)metil]-2-(1,1-dioxo-3,5-dihidro-1,4-benzotiazepín-4-il)-6-metil-quinazolín-4-amina
MA41614A (fr) 2015-02-25 2018-01-02 Alios Biopharma Inc Composés antiviraux
EP3322704B1 (en) 2015-07-16 2019-11-27 H. Hoffnabb-La Roche Ag Crystalline form of n-[(3-amino-3-oxetanyl)methyl]-2-(2,3-dihydro-1,1-dioxido-1,4-benzothiazepin-4(5h)-yl)-6-methyl-4-quinazolinamine for the treatment of respiratory syncytial virus (rsv) infections
WO2019067864A1 (en) 2017-09-29 2019-04-04 Enanta Pharmaceuticals, Inc. PHARMACEUTICAL AGENTS IN COMBINATION AS INHIBITORS OF RSV

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6774134B2 (en) * 2000-12-20 2004-08-10 Bristol-Myers Squibb Company Heterocyclic substituted 2-methyl-benzimidazole antiviral agents
WO2005061513A1 (en) * 2003-12-24 2005-07-07 Biota Scientific Management Pty Ltd Polycyclic agents for the treatment of respiratory syncytial virus infections
WO2009008906A2 (en) * 2007-02-06 2009-01-15 The Trustees Of The University Of Pennsylvania Therapeutic compounds for blocking dna synthesis of pox viruses

Also Published As

Publication number Publication date
HK1197058A1 (en) 2015-01-02
CA2847071A1 (en) 2013-04-18
EP2766370B1 (en) 2016-08-03
KR20140088555A (ko) 2014-07-10
MX2014003701A (es) 2015-04-14
EP2766370A1 (en) 2014-08-20
WO2013053658A1 (en) 2013-04-18
ES2593059T3 (es) 2016-12-05
US8604019B2 (en) 2013-12-10
JP2014530225A (ja) 2014-11-17
RU2014118330A (ru) 2015-11-20
BR112014008783A2 (pt) 2017-04-25
US20130090328A1 (en) 2013-04-11

Similar Documents

Publication Publication Date Title
MY184306A (en) Compounds for the treatment and prophylaxis of respiratory syncytial virus disease
EA026667B9 (ru) Фармацевтическая композиция для лечения вируса гепатита с
UA115320C2 (uk) Інгібітори кінази
MX2014001595A (es) Compuestos de imidazol, composiciones y metodos de uso.
MX363456B (es) Compuestos para tratar atrofia muscular espinal.
MD4602B1 (ro) Inhibitori ai virusului hepatic C
MX345928B (es) Composiciones terapeuticamente activas y metodos de uso de las mismas.
GEP201606532B (en) Benzamide derivatives for inhibiting the activity of abl1, abl2 and bcr-abl1
IN2014DN09434A (es)
WO2011127333A3 (en) Compounds for treating disease, for administering, and for pharmaceutical compositions
IN2014KN00948A (es)
MX2014003701A (es) Compuestos para el tratamiento y profilaxis de enfermedad por el virus sincitial respiratorio.
PH12014501278A1 (en) Kinase inhibitors
MX2013011589A (es) Metodos y composiciones para tratar enfermedad de parkinson.
GEP20186880B (en) 2-amino-3, 5, 5-trifluoro-3, 4, 5, 6-tetrahydropyridines as bace1 inhibitors for treatment of alzheimer's disease
TN2015000293A1 (en) Heterocycle-substituted tetracyclic compounds and methods of use thereof for treatment of viral diseases
MX2014002552A (es) Compuesto pirazol y su uso farmaceutico.
WO2012135615A3 (en) Enopeptins, uses thereof, and methods of synthesis thereto
PH12015500111A1 (en) Difluorolactam compositions for ep4-mediated osteo related diseases and conditions
MX364400B (es) Compuestos de tetraciclina.
GEP20156244B (en) New tertiary 8-hydroxyquinoline-7- carboxamide derivatives and usage thereof
PH12015500373A1 (en) Diazepinone derivatives useful for the treatment of fragile x syndrome, parkinsons or reflux disease
UA104102C2 (en) α-CRYSTALLINE FORM OF CARBABENZPYRIDE
WO2012164055A3 (en) New compounds, synthesis and use thereof in the treatment of pain
UA110849C2 (uk) Сполуки для лікування та профілактики респіраторного синцитіального вірусного захворювання

Legal Events

Date Code Title Description
FG Grant or registration