MX219130B - Metodo para producir vitamina. - Google Patents
Metodo para producir vitamina.Info
- Publication number
- MX219130B MX219130B MXPA01000216A MX219130B MX 219130 B MX219130 B MX 219130B MX PA01000216 A MXPA01000216 A MX PA01000216A MX 219130 B MX219130 B MX 219130B
- Authority
- MX
- Mexico
- Prior art keywords
- geranylgeraniol
- microorganism
- farnesol
- vitamin production
- phosphate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
- C07C403/08—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/24—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
- C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P9/00—Preparation of organic compounds containing a metal or atom other than H, N, C, O, S or halogen
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01Q—ANTENNAS, i.e. RADIO AERIALS
- H01Q1/00—Details of, or arrangements associated with, antennas
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9198398P | 1998-07-06 | 1998-07-06 | |
| US9196498P | 1998-07-06 | 1998-07-06 | |
| US9195198P | 1998-07-06 | 1998-07-06 | |
| PCT/US1999/015264 WO2000001650A1 (en) | 1998-07-06 | 1999-07-06 | Method of vitamin production |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MXPA01000216A MXPA01000216A (es) | 2002-10-17 |
| MX219130B true MX219130B (es) | 2004-02-10 |
Family
ID=27377004
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA04002408 MX276941B (es) | 1998-07-06 | 1999-07-06 | Metodo para producir vitamina. |
| MXPA01000216 MX219130B (es) | 1998-07-06 | 1999-07-06 | Metodo para producir vitamina. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA04002408 MX276941B (es) | 1998-07-06 | 1999-07-06 | Metodo para producir vitamina. |
Country Status (11)
| Country | Link |
|---|---|
| EP (3) | EP1095002A4 (es) |
| JP (1) | JP4579415B2 (es) |
| CN (1) | CN1330621A (es) |
| AT (2) | ATE537265T1 (es) |
| AU (1) | AU4863099A (es) |
| CA (2) | CA2831321C (es) |
| DE (1) | DE69943009D1 (es) |
| DK (3) | DK2100963T3 (es) |
| ES (2) | ES2379212T3 (es) |
| MX (2) | MX276941B (es) |
| WO (1) | WO2000001650A1 (es) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2305825B1 (en) | 1998-07-06 | 2015-01-14 | DCV Inc. doing business as Bio-Technical Resourses | Method of vitamin production |
| BR0010616A (pt) | 1999-04-15 | 2002-05-07 | Calgene Llc | Sequências de ácido nucléico a proteìnas envolvidas em sìntese de isoprenóide |
| ATE353972T1 (de) * | 2000-03-02 | 2007-03-15 | Toudai Tlo Ltd | VERFAHREN ZUM SCREENING NACH SUBSTANZEN, DIE SPEZIFISCH DEN ßNICHT-MEVALONATß-PFAD INHIBIEREN |
| US6872815B1 (en) | 2000-10-14 | 2005-03-29 | Calgene Llc | Nucleic acid sequences to proteins involved in tocopherol synthesis |
| WO2002010398A2 (en) | 2000-07-31 | 2002-02-07 | Hahn Frederick M | Manipulation of genes of the mevalonate and isoprenoid pathways to create novel traits in transgenic organisms |
| WO2002012478A2 (en) | 2000-08-07 | 2002-02-14 | Monsanto Technology, Llc | Methyl-d-erythritol phosphate pathway genes |
| EP1354956A4 (en) * | 2000-12-28 | 2004-10-27 | Toyota Motor Co Ltd | PROCESS FOR PRODUCING PRENYL ALCOHOL |
| JP2002253284A (ja) * | 2000-12-28 | 2002-09-10 | Toyota Motor Corp | 微生物によるゲラニルゲラニオール及びその類縁化合物の製造方法 |
| JP4013535B2 (ja) | 2000-12-28 | 2007-11-28 | トヨタ自動車株式会社 | 微生物によるプレニルアルコールの高生産方法 |
| CN1491282A (zh) * | 2000-12-28 | 2004-04-21 | 丰田自动车株式会社 | 异戊二烯醇的制备方法 |
| JP2003088368A (ja) * | 2001-09-18 | 2003-03-25 | Toyota Motor Corp | プレニルアルコールの製造方法 |
| JP3838033B2 (ja) * | 2000-12-28 | 2006-10-25 | トヨタ自動車株式会社 | プレニルアルコールの製造方法 |
| US7161061B2 (en) | 2001-05-09 | 2007-01-09 | Monsanto Technology Llc | Metabolite transporters |
| JP2004533244A (ja) | 2001-05-09 | 2004-11-04 | モンサント テクノロジー リミテッド ライアビリティー カンパニー | ＴｙｒＡ遺伝子及びその使用法 |
| US6989257B2 (en) * | 2001-06-06 | 2006-01-24 | Dsm Ip Assets B.V. | Isoprenoid production |
| US7244877B2 (en) | 2001-08-17 | 2007-07-17 | Monsanto Technology Llc | Methyltransferase from cotton and uses thereof |
| CN100400661C (zh) | 2001-10-25 | 2008-07-09 | 孟山都技术有限公司 | 芳族甲基转移酶及其应用 |
| US7192751B2 (en) | 2001-12-06 | 2007-03-20 | The Regents Of The University Of California | Biosynthesis of amorpha-4,11-diene |
| US7172886B2 (en) | 2001-12-06 | 2007-02-06 | The Regents Of The University Of California | Biosynthesis of isopentenyl pyrophosphate |
| CA2478957C (en) | 2002-03-19 | 2013-07-02 | Monsanto Technology, Llc | Homogentisate prenyl transferase ("hpt") nucleic acids and polypeptides, and uses thereof |
| MXPA04012062A (es) | 2002-06-21 | 2005-03-07 | Dsm Ip Assets Bv | Proceso para producir carotenoides. |
| CN1681928A (zh) | 2002-08-05 | 2005-10-12 | 孟山都技术公司 | 生育酚生物合成相关基因及其用途 |
| MXPA05002120A (es) | 2002-09-27 | 2005-06-06 | Dsm Ip Assets Bv | Gen de escualeno sintasa. |
| MXPA06013502A (es) | 2004-05-21 | 2007-03-01 | Univ California | Metodo para mejorar la produccion de compuestos isoprenoides. |
| US8828684B2 (en) * | 2004-07-27 | 2014-09-09 | The Regents Of The University Of California | Genetically modified host cells and use of same for producing isoprenoid compounds |
| EP1866428A2 (en) | 2005-03-18 | 2007-12-19 | Microbia, Inc. | Production of carotenoids in oleaginous yeast and fungi |
| JP4824985B2 (ja) * | 2005-10-13 | 2011-11-30 | 株式会社Ａｄｅｋａ | ファルネシル二リン酸の製造方法 |
| US8691555B2 (en) | 2006-09-28 | 2014-04-08 | Dsm Ip Assests B.V. | Production of carotenoids in oleaginous yeast and fungi |
| CN101765661B (zh) | 2007-06-01 | 2014-08-06 | 索拉兹米公司 | 在微生物中生产油 |
| US11725225B2 (en) | 2007-09-20 | 2023-08-15 | Amyris, Inc. | Production of isoprenoids |
| JP5174430B2 (ja) * | 2007-11-06 | 2013-04-03 | 花王株式会社 | ２−フェニルエチルアルコールの製造方法 |
| WO2010031076A2 (en) | 2008-09-15 | 2010-03-18 | Danisco Us Inc. | Conversion of prenyl derivatives to isoprene |
| JP6109475B2 (ja) * | 2008-11-28 | 2017-04-05 | テラヴィア ホールディングス， インコーポレイテッド | 従属栄養微生物における、用途に応じた油の生産 |
| CA3039432A1 (en) | 2010-05-28 | 2011-12-01 | Corbion Biotech, Inc. | Tailored oils produced from recombinant heterotrophic microorganisms |
| CN105671108A (zh) | 2010-06-02 | 2016-06-15 | 沃维公司 | 甜菊糖苷的重组生产 |
| SG190154A1 (en) | 2010-11-03 | 2013-06-28 | Solazyme Inc | Microbial oils with lowered pour points, dielectric fluids produced therefrom, and related methods |
| US9249436B2 (en) | 2011-02-02 | 2016-02-02 | Solazyme, Inc. | Tailored oils produced from recombinant oleaginous microorganisms |
| KR20140033378A (ko) | 2011-05-06 | 2014-03-18 | 솔라짐, 인코포레이티드 | 자일로오스를 대사시키는 유전자 조작된 미생물 |
| CA2832979C (en) * | 2011-05-09 | 2020-04-14 | Amyris, Inc. | Production of acetyl-coenzyme a derived compounds |
| EP3009508B1 (en) | 2011-08-08 | 2020-11-25 | Evolva SA | Recombinant production of steviol glycosides |
| KR20150001830A (ko) | 2012-04-18 | 2015-01-06 | 솔라짐, 인코포레이티드 | 맞춤 오일 |
| CN105051195B (zh) | 2013-02-06 | 2019-09-06 | 埃沃尔瓦公司 | 用于提高莱鲍迪苷d和莱鲍迪苷m之产生的方法 |
| CA2900882A1 (en) | 2013-02-11 | 2014-08-14 | Evolva Sa | Efficient production of steviol glycosides in recombinants hosts |
| WO2014176515A2 (en) | 2013-04-26 | 2014-10-30 | Solazyme, Inc. | Low polyunsaturated fatty acid oils and uses thereof |
| US10053715B2 (en) | 2013-10-04 | 2018-08-21 | Corbion Biotech, Inc. | Tailored oils |
| ES2764273T3 (es) | 2014-07-10 | 2020-06-02 | Corbion Biotech Inc | Nuevos genes de cetoacil ACP sintasa y uso de los mismos |
| MX2017001859A (es) | 2014-08-11 | 2017-04-11 | Evolva Sa | Produccion de glicosidos de esteviol en hospederos recombinantes. |
| AU2015314251A1 (en) | 2014-09-09 | 2017-03-16 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| SG11201705606PA (en) | 2015-01-30 | 2017-08-30 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| CA2979931A1 (en) | 2015-03-16 | 2016-09-22 | Dsm Ip Assets B.V. | Udp-glycosyltransferases |
| AU2016307066A1 (en) | 2015-08-07 | 2018-02-08 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| CN105153102A (zh) * | 2015-09-30 | 2015-12-16 | 宜春大海龟生命科学有限公司 | 以混合生育酚为原料制备α-生育酚的方法 |
| AU2017251462B2 (en) | 2016-04-13 | 2022-02-03 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| EP3458599A1 (en) | 2016-05-16 | 2019-03-27 | Evolva SA | Production of steviol glycosides in recombinant hosts |
| WO2018083338A1 (en) | 2016-11-07 | 2018-05-11 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| KR20200095534A (ko) | 2017-12-07 | 2020-08-10 | 지머젠 인코포레이티드 | 발효에 의한 (6e)-8-히드록시제라니올의 제조를 위해 조작된 생합성 경로 |
| JP2021506316A (ja) | 2017-12-21 | 2021-02-22 | ザイマージェン インコーポレイテッド | ネペタラクトールオキシドレダクターゼ、ネペタラクトールシンターゼ、及びネペタラクトンを産生する能力がある微生物 |
| CN109609579B (zh) * | 2018-12-31 | 2022-04-05 | 陕西师范大学 | 一种产β-胡萝卜素的基因工程菌及其构建方法 |
| CN109884216A (zh) * | 2019-04-10 | 2019-06-14 | 西南医科大学 | 一种高效液相色谱测定载药胶束中法尼醛含量的方法 |
| CN110903190B (zh) * | 2019-12-09 | 2022-07-12 | 万华化学集团股份有限公司 | 一种维生素a及维生素a酯的制备方法 |
| CN110950791B (zh) * | 2019-12-09 | 2021-12-14 | 万华化学集团股份有限公司 | 一种维生素a及维生素a酯制备方法 |
| JP2023506144A (ja) * | 2019-12-23 | 2023-02-15 | ディーエスエム アイピー アセッツ ビー．ブイ． | 脱水素化方法 |
| CN113621631A (zh) * | 2021-08-11 | 2021-11-09 | 昆明理工大学 | 一种甲羟戊酸激酶基因rkmk及其应用 |
| CN113969288A (zh) * | 2021-10-29 | 2022-01-25 | 湖北冠众通科技有限公司 | 一种高产法尼醇基因工程菌及其构建方法与应用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE810299A (fr) * | 1974-01-29 | 1974-05-16 | Procede de fabrication de composes contenant un noyau chromane. | |
| US3862988A (en) | 1974-05-23 | 1975-01-28 | Eastman Kodak Co | 4,8 Dimethyl- 12-oxotridecanal |
| US3917710A (en) | 1974-05-23 | 1975-11-04 | Eastman Kodak Co | Preparation of phytone via the addition of dimethylketene to 4,8-dimethyl-12-oxotridecanal |
| GB1479272A (en) * | 1974-12-23 | 1977-07-13 | Kuraray Co | Process for preparing a stereospecific farnesol |
| US4225734A (en) | 1978-08-08 | 1980-09-30 | The Regents Of The University Of California | Process for producing symmetrical olefins |
| US4743546A (en) | 1985-02-13 | 1988-05-10 | Biotechnica International, Inc. | Controlled gene excision |
| US4871721A (en) | 1988-01-11 | 1989-10-03 | E. R. Squibb & Sons, Inc. | Phosphorus-containing squalene synthetase inhibitors |
| US5589372A (en) | 1990-09-26 | 1996-12-31 | E. R. Squibb & Sons, Inc. | Squalene synthetase |
| US5460949A (en) | 1990-11-15 | 1995-10-24 | Amoco Corporation | Method and composition for increasing the accumulation of squalene and specific sterols in yeast |
| US5475029A (en) | 1993-07-08 | 1995-12-12 | The Board Of Trustees Of The Leland Stanford Junior University | Farnesyl compounds as cholesterol lowering agents |
| JP3657298B2 (ja) | 1994-11-08 | 2005-06-08 | 株式会社クラレ | ゲラニルゲラニオ−ルの製造方法 |
| US5556990A (en) | 1994-12-16 | 1996-09-17 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Polyarylcarbamoylaza- and -carbamoylalkanedioic acids |
| JP3120684B2 (ja) | 1995-02-14 | 2000-12-25 | トヨタ自動車株式会社 | ゲラニルゲラニル二リン酸を合成する変異型ファルネシル二リン酸合成酵素及びそれをコードするｄｎａ |
| JP3151371B2 (ja) * | 1995-03-10 | 2001-04-03 | 麒麟麦酒株式会社 | カロチノイド生産量の増量に有用なｄｎａ鎖 |
| US5912154A (en) | 1995-12-07 | 1999-06-15 | Yale University | Geranylgeranyl diphosphate synthase proteins, nucleic acid molecules and uses thereof |
| JP2000507087A (ja) * | 1995-12-22 | 2000-06-13 | ギスト ブロカデス ベスローテン ファンノートシャップ | ファフィア株を形質転換する改良法、そのようにして得られた形質転換したファフィア株及び前記方法における組換えｄｎａ |
| US5744341A (en) * | 1996-03-29 | 1998-04-28 | University Of Maryland College Park | Genes of carotenoid biosynthesis and metabolism and a system for screening for such genes |
| EP0955363A3 (en) * | 1998-05-06 | 2004-01-28 | F. Hoffmann-La Roche Ag | Dna sequences encoding enzymes involved in production of isoprenoids |
-
1999
- 1999-07-06 EP EP99932295A patent/EP1095002A4/en not_active Withdrawn
- 1999-07-06 MX MXPA04002408 patent/MX276941B/es unknown
- 1999-07-06 EP EP08003596A patent/EP1947189B1/en not_active Expired - Lifetime
- 1999-07-06 CN CN99810559A patent/CN1330621A/zh active Pending
- 1999-07-06 DE DE69943009T patent/DE69943009D1/de not_active Expired - Lifetime
- 1999-07-06 JP JP2000558056A patent/JP4579415B2/ja not_active Expired - Lifetime
- 1999-07-06 MX MXPA01000216 patent/MX219130B/es unknown
- 1999-07-06 CA CA2831321A patent/CA2831321C/en not_active Expired - Lifetime
- 1999-07-06 DK DK09004155.9T patent/DK2100963T3/da active
- 1999-07-06 EP EP09004155A patent/EP2100963B1/en not_active Expired - Lifetime
- 1999-07-06 DK DK10180179T patent/DK2305825T3/en active
- 1999-07-06 ES ES09004155T patent/ES2379212T3/es not_active Expired - Lifetime
- 1999-07-06 DK DK08003596.7T patent/DK1947189T3/da active
- 1999-07-06 AU AU48630/99A patent/AU4863099A/en not_active Abandoned
- 1999-07-06 CA CA2331343A patent/CA2331343C/en not_active Expired - Lifetime
- 1999-07-06 WO PCT/US1999/015264 patent/WO2000001650A1/en active Application Filing
- 1999-07-06 AT AT09004155T patent/ATE537265T1/de active
- 1999-07-06 ES ES10180179.3T patent/ES2534937T3/es not_active Expired - Lifetime
- 1999-07-06 AT AT08003596T patent/ATE490332T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP2100963A1 (en) | 2009-09-16 |
| EP1095002A1 (en) | 2001-05-02 |
| EP1095002A4 (en) | 2005-08-03 |
| ATE490332T1 (de) | 2010-12-15 |
| DK2305825T3 (en) | 2015-03-02 |
| AU4863099A (en) | 2000-01-24 |
| ES2379212T3 (es) | 2012-04-23 |
| MXPA01000216A (es) | 2002-10-17 |
| EP1947189A2 (en) | 2008-07-23 |
| CA2831321C (en) | 2018-05-15 |
| ES2534937T3 (es) | 2015-04-30 |
| DE69943009D1 (de) | 2011-01-13 |
| CA2831321A1 (en) | 2000-01-13 |
| WO2000001650A1 (en) | 2000-01-13 |
| EP2100963B1 (en) | 2011-12-14 |
| JP4579415B2 (ja) | 2010-11-10 |
| CN1330621A (zh) | 2002-01-09 |
| ATE537265T1 (de) | 2011-12-15 |
| CA2331343A1 (en) | 2000-01-13 |
| DK1947189T3 (da) | 2011-03-14 |
| CA2331343C (en) | 2014-01-14 |
| DK2100963T3 (da) | 2012-04-02 |
| EP1947189A3 (en) | 2008-10-08 |
| EP1947189B1 (en) | 2010-12-01 |
| JP2002519049A (ja) | 2002-07-02 |
| MX276941B (es) | 2010-06-28 |
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