MX2022001029A - Inhibidor de sglts/dpp4 y aplicación del mismo. - Google Patents

Inhibidor de sglts/dpp4 y aplicación del mismo.

Info

Publication number
MX2022001029A
MX2022001029A MX2022001029A MX2022001029A MX2022001029A MX 2022001029 A MX2022001029 A MX 2022001029A MX 2022001029 A MX2022001029 A MX 2022001029A MX 2022001029 A MX2022001029 A MX 2022001029A MX 2022001029 A MX2022001029 A MX 2022001029A
Authority
MX
Mexico
Prior art keywords
application
sglts
dpp4
dpp4 inhibitor
sglt1
Prior art date
Application number
MX2022001029A
Other languages
English (en)
Inventor
Yi Li
Qinghua Mao
Shuhui Chen
Chengde Wu
Tao Yu
Original Assignee
Dongbao Purple Star Hangzhou Biopharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dongbao Purple Star Hangzhou Biopharmaceutical Co Ltd filed Critical Dongbao Purple Star Hangzhou Biopharmaceutical Co Ltd
Publication of MX2022001029A publication Critical patent/MX2022001029A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/06—Heterocyclic radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical

Abstract

Una clase de compuestos como un inhibidor triple de SGLT1/SGLT2/DPP4, y una aplicación en la preparación de un fármaco que actúa como el inhibidor triple de SGLT1/SGLT2/DPP4. Los compuestos representados por la fórmula (I) y los isómeros y las sales farmacéuticamente aceptables de los mismos, están específicamente implicados. (ver fórmula).
MX2022001029A 2019-07-26 2020-07-24 Inhibidor de sglts/dpp4 y aplicación del mismo. MX2022001029A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201910683107 2019-07-26
CN202010105252 2020-02-20
PCT/CN2020/104534 WO2021018046A1 (zh) 2019-07-26 2020-07-24 一种SGLTs/DPP4抑制剂及其应用

Publications (1)

Publication Number Publication Date
MX2022001029A true MX2022001029A (es) 2022-05-24

Family

ID=74229412

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022001029A MX2022001029A (es) 2019-07-26 2020-07-24 Inhibidor de sglts/dpp4 y aplicación del mismo.

Country Status (8)

Country Link
US (1) US20220259247A1 (es)
EP (1) EP4005568A4 (es)
JP (1) JP7299408B2 (es)
CN (1) CN114585358B (es)
AU (1) AU2020323037B2 (es)
BR (1) BR112022001314A2 (es)
MX (1) MX2022001029A (es)
WO (1) WO2021018046A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102471055B1 (ko) * 2019-07-26 2022-11-28 메드샤인 디스커버리 아이엔씨. Sglt2/dpp4 억제제 및 이의 용도
WO2022160737A1 (zh) * 2021-01-26 2022-08-04 东宝紫星(杭州)生物医药有限公司 四氢吡喃环类化合物的晶型及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS52365B (en) * 2004-03-16 2012-12-31 Boehringer Ingelheim International Gmbh BENZOL DERIVATIVES SUBSTITUTED BY GLUCOPYRANOSIL, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS, THEIR USE AND THE PROCEDURE FOR THEIR PRODUCTION
ATE407938T1 (de) 2004-12-16 2008-09-15 Boehringer Ingelheim Int Glucopyranosyl-substituierte benzen-derivate, medikamente mit solchen verbindungen, ihre verwendung und herstellungsverfahren dafür
US7745414B2 (en) * 2006-02-15 2010-06-29 Boehringer Ingelheim International Gmbh Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture
EP2054426A1 (en) * 2006-08-15 2009-05-06 Boehringer Ingelheim International GmbH Glucopyranosyl-substituted cyclopropylbenzene derivatives, pharmaceutical compositions containing such compounds, their use as sglt inhibitors and process for their manufacture
TWI499414B (zh) 2006-09-29 2015-09-11 Lexicon Pharmaceuticals Inc 鈉與葡萄糖第２型共同運輸體（ｃｏ-ｔｒａｎｓｐｏｒｔｅｒ ２）的抑制物與其應用方法
EA018495B1 (ru) 2006-11-09 2013-08-30 Бёрингер Ингельхайм Интернациональ Гмбх Комбинированное лечение ингибиторами sglt-2 (натрийзависимый сопереносчик глюкозы 2) и содержащими их фармацевтическими композициями
US7846945B2 (en) * 2007-03-08 2010-12-07 Lexicon Pharmaceuticals, Inc. Piperdine-based inhibitors of sodium glucose co-transporter 2 and methods of their use
TWI631963B (zh) 2011-01-05 2018-08-11 雷西肯製藥股份有限公司 包含鈉－葡萄糖共同輸送體１與２之抑制劑的組合物與應用方法
NZ707859A (en) * 2012-11-20 2019-03-29 Lexicon Pharmaceuticals Inc Inhibitors of sodium glucose cotransporter 1
CN105294694B (zh) * 2014-06-18 2019-01-04 四川海思科制药有限公司 氨基六元环类衍生物及其在医药上的应用

Also Published As

Publication number Publication date
CN114585358A (zh) 2022-06-03
AU2020323037A1 (en) 2022-03-17
JP7299408B2 (ja) 2023-06-27
EP4005568A1 (en) 2022-06-01
CN114585358B (zh) 2023-11-10
US20220259247A1 (en) 2022-08-18
JP2022542146A (ja) 2022-09-29
BR112022001314A2 (pt) 2022-03-22
AU2020323037B2 (en) 2023-08-03
WO2021018046A1 (zh) 2021-02-04
EP4005568A4 (en) 2023-09-06

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