MX2021010595A - Composicion farmaceutica, preparacion y usos de la misma. - Google Patents
Composicion farmaceutica, preparacion y usos de la misma.Info
- Publication number
- MX2021010595A MX2021010595A MX2021010595A MX2021010595A MX2021010595A MX 2021010595 A MX2021010595 A MX 2021010595A MX 2021010595 A MX2021010595 A MX 2021010595A MX 2021010595 A MX2021010595 A MX 2021010595A MX 2021010595 A MX2021010595 A MX 2021010595A
- Authority
- MX
- Mexico
- Prior art keywords
- pharmaceutical compound
- carrier
- biocompatible nanoparticle
- subject
- need
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
- A61K47/6911—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
- A61K47/6927—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores
- A61K47/6929—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores the form being a nanoparticle, e.g. an immuno-nanoparticle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Abstract
La presente invención se refiere a una composición farmacéutica que comprende la combinación de (i) al menos una nanopartícula biocompatible y de (ii) al menos un vehículo que comprende al menos un compuesto farmacéutico, para administración a un sujeto que precisa dicho compuesto farmacéutico, en donde la combinación de la al menos una nanopartícula biocompatible y el al menos un vehículo que comprende el(los) compuesto(s) farmacéutico(s) potencia el(los) compuesto(s) de eficacia de interés. La dimensión más larga de la nanopartícula biocompatible está normalmente entre aproximadamente 4 y aproximadamente 500 nm y su valor absoluto de carga superficial es de al menos 10 mV (|10 mV|). El vehículo además está desprovisto de cualquier agente estéricamente estabilizador de superficie. La invención también se refiere a dicha composición para su uso en la administración del(de los) compuesto(s) farmacéutico(s) en un sujeto que lo precisa, en donde la al menos una nanopartícula biocompatible y el al menos un vehículo que comprende el al menos un compuesto farmacéutico se administran por separado en un sujeto que necesita dicho compuesto farmacéutico, normalmente entre más de 5 minutos y aproximadamente 72 horas uno con respecto a otro.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP14306875 | 2014-11-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2021010595A true MX2021010595A (es) | 2021-09-23 |
Family
ID=52013982
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2017006812A MX2017006812A (es) | 2014-11-25 | 2015-11-24 | Composición farmacéutica, preparación y usos de la misma. |
MX2021010595A MX2021010595A (es) | 2014-11-25 | 2017-05-24 | Composicion farmaceutica, preparacion y usos de la misma. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2017006812A MX2017006812A (es) | 2014-11-25 | 2015-11-24 | Composición farmacéutica, preparación y usos de la misma. |
Country Status (18)
Country | Link |
---|---|
US (1) | US10765632B2 (es) |
EP (1) | EP3236934A1 (es) |
JP (1) | JP6789960B2 (es) |
KR (1) | KR20170093860A (es) |
CN (1) | CN107106703A (es) |
AR (1) | AR102782A1 (es) |
AU (1) | AU2015352685B2 (es) |
BR (1) | BR112017010953B1 (es) |
CA (1) | CA2968919C (es) |
EA (1) | EA201791147A1 (es) |
HK (1) | HK1245085A1 (es) |
IL (2) | IL252462B (es) |
MX (2) | MX2017006812A (es) |
NZ (1) | NZ769187A (es) |
SG (1) | SG11201704219UA (es) |
TW (1) | TW201628656A (es) |
UA (1) | UA123665C2 (es) |
WO (1) | WO2016083333A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2015016456A (es) | 2013-05-30 | 2016-03-03 | Nanobiotix | Composicion farmaceutica, preparacion y sus usos. |
PT3229843T (pt) | 2014-11-25 | 2020-03-06 | Curadigm Sas | Composição farmacêutica, a sua preparação e as suas utilizações |
JP6835733B2 (ja) | 2014-11-25 | 2021-02-24 | キュラディグム・エスアエスCuradigm Sas | 医薬組成物、その調製法及び使用 |
EP3229776B1 (en) | 2014-11-25 | 2023-06-28 | Curadigm Sas | Pharmaceutical composition combining at least two distinct nanoparticles and a pharmaceutical compound, preparation and uses thereof |
TW201705977A (zh) | 2015-05-28 | 2017-02-16 | 奈諾生技公司 | 作為治療疫苗之奈米顆粒 |
Family Cites Families (36)
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US4280918A (en) | 1980-03-10 | 1981-07-28 | International Business Machines Corporation | Magnetic particle dispersions |
GB9509321D0 (en) | 1995-05-09 | 1995-06-28 | Zylepsis Ltd | Methods of and substances for inhibiting oxidative enzymes |
JPH10120597A (ja) | 1996-10-22 | 1998-05-12 | Eiken Chem Co Ltd | リンパ節高集積性コロイド粒子 |
US20050090732A1 (en) | 2003-10-28 | 2005-04-28 | Triton Biosystems, Inc. | Therapy via targeted delivery of nanoscale particles |
CN100563718C (zh) * | 2003-12-22 | 2009-12-02 | 伯拉考开发股份有限公司 | 用于反差成像的充气微囊组件 |
JP2007523090A (ja) * | 2004-02-10 | 2007-08-16 | バーンズ−ジューイッシュ ホスピタル | デコイ系を用いたターゲティングされた微粒子剤の有効性および安全性の改善方法 |
US20060264804A1 (en) * | 2005-04-07 | 2006-11-23 | Yoram Karmon | Device and kit for delivery of encapsulated substances and methods of use thereof |
WO2006127962A2 (en) * | 2005-05-25 | 2006-11-30 | Becton, Dickinson And Comapny | Particulate formulations for intradermal delivery of biologically active agents |
DE102005039579B4 (de) | 2005-08-19 | 2022-06-30 | Magforce Ag | Verfahren zur Einschleusung von therapeutischen Substanzen in Zellen |
US20090130050A1 (en) * | 2006-03-24 | 2009-05-21 | Toto Ltd. | Titanium Oxide Composite Particles, Dispersion Liquid Thereof, and Process for Producing Them |
US20100233219A1 (en) | 2006-03-30 | 2010-09-16 | Fujifilm Corporation | Inorganic nanoparticle compromising an active substance immobilized on the surface and a polymer |
JP2009536162A (ja) | 2006-05-04 | 2009-10-08 | ユニバーシティー オブ サウス オーストラリア | ナノ粒子被覆カプセルからの薬物放出 |
US20090092661A1 (en) * | 2007-08-21 | 2009-04-09 | Anthony Huang | Liposome compositions for in vivo administration of boronic acid compounds |
FR2922106B1 (fr) | 2007-10-16 | 2011-07-01 | Univ Claude Bernard Lyon | Utilisation de nanoparticules a base de lanthanides comme agents radiosensibilisants. |
EP2231765A2 (en) | 2007-12-21 | 2010-09-29 | University Of Guelph | Polysaccharide nanoparticles |
WO2009105774A2 (en) | 2008-02-21 | 2009-08-27 | Sequoia Pharmaceuticals, Inc. | Amino acid inhibitors of cytochrome p450 |
WO2009142754A1 (en) | 2008-05-22 | 2009-11-26 | Goverment Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Dendritic conjugates and methods of use |
EP2130553A1 (en) | 2008-06-05 | 2009-12-09 | Nanobiotix | Inorganic nanoparticles of high density to destroy cells in-vivo |
US20130023714A1 (en) | 2008-10-26 | 2013-01-24 | Board Of Regents, The University Of Texas Systems | Medical and Imaging Nanoclusters |
GB0921596D0 (en) | 2009-12-09 | 2010-01-27 | Isis Innovation | Particles for the treatment of cancer in combination with radiotherapy |
CN102781472B (zh) | 2010-02-17 | 2014-07-02 | 国立大学法人神户大学 | 放射线治疗剂 |
HUE027749T2 (en) | 2010-03-26 | 2016-10-28 | Abraxis Bioscience Llc | Methods of treating hepatocellular carcinoma |
GB201009455D0 (en) | 2010-06-04 | 2010-07-21 | King S College London | Nanoparticles and their uses in molecular imaging |
WO2012051220A1 (en) | 2010-10-11 | 2012-04-19 | Wichita State University | Composite magnetic nanoparticle drug delivery system |
US20140227343A1 (en) | 2011-01-31 | 2014-08-14 | Centre National De La Recherche Scientifique | Method of monitoring the release from liposomes of a product of interest using superparamagnetic nanoparticles |
DK2670394T3 (en) | 2011-01-31 | 2019-01-14 | Nanobiotix | NANOPARTICLE DELIVERY SYSTEMS, PREPARATION AND APPLICATIONS THEREOF |
US10251841B2 (en) | 2011-10-17 | 2019-04-09 | Trustees Of Boston University | Polymeric depots for localization of agent to biological sites |
US20150209397A1 (en) | 2012-09-07 | 2015-07-30 | Carnegie Mellon University | Methods and materials for reducing reticuloendothelial system clearance of particles from a subject |
ITRM20120480A1 (it) | 2012-10-09 | 2014-04-10 | Uni Degli Studi Camerino | Nanoparticelle lipidiche multicomponenti e procedimenti per la loro preparazione. |
US20140186447A1 (en) | 2012-12-28 | 2014-07-03 | Abraxis Bioscience, Llc | Nanoparticle compositions of albumin and paclitaxel |
MX2015016456A (es) * | 2013-05-30 | 2016-03-03 | Nanobiotix | Composicion farmaceutica, preparacion y sus usos. |
EP2886128A1 (en) | 2013-12-20 | 2015-06-24 | Nanobiotix | Pharmaceutical composition comprising nanoparticles, preparation and uses thereof |
MX2017006813A (es) | 2014-11-25 | 2018-01-30 | Nanobiotix | Composicion farmaceutica, preparacion y usos de la misma. |
EP3229776B1 (en) * | 2014-11-25 | 2023-06-28 | Curadigm Sas | Pharmaceutical composition combining at least two distinct nanoparticles and a pharmaceutical compound, preparation and uses thereof |
JP6835733B2 (ja) | 2014-11-25 | 2021-02-24 | キュラディグム・エスアエスCuradigm Sas | 医薬組成物、その調製法及び使用 |
PT3229843T (pt) | 2014-11-25 | 2020-03-06 | Curadigm Sas | Composição farmacêutica, a sua preparação e as suas utilizações |
-
2015
- 2015-11-24 AR ARP150103850A patent/AR102782A1/es unknown
- 2015-11-24 MX MX2017006812A patent/MX2017006812A/es unknown
- 2015-11-24 SG SG11201704219UA patent/SG11201704219UA/en unknown
- 2015-11-24 JP JP2017546031A patent/JP6789960B2/ja active Active
- 2015-11-24 TW TW104139006A patent/TW201628656A/zh unknown
- 2015-11-24 CA CA2968919A patent/CA2968919C/en active Active
- 2015-11-24 UA UAA201706347A patent/UA123665C2/uk unknown
- 2015-11-24 EA EA201791147A patent/EA201791147A1/ru unknown
- 2015-11-24 BR BR112017010953-0A patent/BR112017010953B1/pt active IP Right Grant
- 2015-11-24 US US15/529,106 patent/US10765632B2/en active Active
- 2015-11-24 WO PCT/EP2015/077425 patent/WO2016083333A1/en active Application Filing
- 2015-11-24 KR KR1020177017322A patent/KR20170093860A/ko active IP Right Grant
- 2015-11-24 NZ NZ769187A patent/NZ769187A/en unknown
- 2015-11-24 EP EP15798435.2A patent/EP3236934A1/en active Pending
- 2015-11-24 AU AU2015352685A patent/AU2015352685B2/en active Active
- 2015-11-24 CN CN201580071112.9A patent/CN107106703A/zh active Pending
-
2017
- 2017-05-23 IL IL252462A patent/IL252462B/en unknown
- 2017-05-24 MX MX2021010595A patent/MX2021010595A/es unknown
-
2018
- 2018-04-03 HK HK18104437.3A patent/HK1245085A1/zh unknown
-
2022
- 2022-01-25 IL IL290114A patent/IL290114A/en unknown
Also Published As
Publication number | Publication date |
---|---|
HK1245085A1 (zh) | 2018-08-24 |
US20170258721A1 (en) | 2017-09-14 |
SG11201704219UA (en) | 2017-06-29 |
NZ769187A (en) | 2023-07-28 |
CA2968919C (en) | 2023-07-18 |
EP3236934A1 (en) | 2017-11-01 |
CN107106703A (zh) | 2017-08-29 |
BR112017010953B1 (pt) | 2024-01-16 |
EA201791147A1 (ru) | 2017-11-30 |
AU2015352685B2 (en) | 2020-09-17 |
MX2017006812A (es) | 2018-02-12 |
AU2015352685A1 (en) | 2017-07-13 |
CA2968919A1 (en) | 2016-06-02 |
KR20170093860A (ko) | 2017-08-16 |
IL290114A (en) | 2022-03-01 |
BR112017010953A2 (pt) | 2018-02-14 |
WO2016083333A1 (en) | 2016-06-02 |
US10765632B2 (en) | 2020-09-08 |
TW201628656A (zh) | 2016-08-16 |
JP6789960B2 (ja) | 2020-11-25 |
NZ732995A (en) | 2021-01-29 |
IL252462A0 (en) | 2017-07-31 |
JP2017538783A (ja) | 2017-12-28 |
IL252462B (en) | 2022-03-01 |
UA123665C2 (uk) | 2021-05-12 |
AR102782A1 (es) | 2017-03-22 |
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