MX2021007625A - Formulacion de nicotina liquida que comprende un solvente parcialmente soluble en agua. - Google Patents

Formulacion de nicotina liquida que comprende un solvente parcialmente soluble en agua.

Info

Publication number
MX2021007625A
MX2021007625A MX2021007625A MX2021007625A MX2021007625A MX 2021007625 A MX2021007625 A MX 2021007625A MX 2021007625 A MX2021007625 A MX 2021007625A MX 2021007625 A MX2021007625 A MX 2021007625A MX 2021007625 A MX2021007625 A MX 2021007625A
Authority
MX
Mexico
Prior art keywords
water
nicotine formulation
liquid nicotine
aerosol
partially water
Prior art date
Application number
MX2021007625A
Other languages
English (en)
Inventor
Aline Vuarnoz-Bize
Jean-Pierre Schaller
Original Assignee
Philip Morris Products Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philip Morris Products Sa filed Critical Philip Morris Products Sa
Publication of MX2021007625A publication Critical patent/MX2021007625A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A24B15/167—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/24—Treatment of tobacco products or tobacco substitutes by extraction; Tobacco extracts
    • A24B15/241—Extraction of specific substances
    • A24B15/243—Nicotine
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A24B15/32—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances by acyclic compounds
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/05—Devices without heating means
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/10—Devices using liquid inhalable precursors
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/40—Constructional details, e.g. connection of cartridges and battery parts
    • A24F40/42—Cartridges or containers for inhalable precursors
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/40—Constructional details, e.g. connection of cartridges and battery parts
    • A24F40/46—Shape or structure of electric heating means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Manufacture Of Tobacco Products (AREA)

Abstract

Una formulación de nicotina líquida para su uso en un sistema generador de aerosol, la formulación de nicotina líquida comprende: agua; y uno o más solventes parcialmente solubles en agua, inmiscibles en agua que tienen una solubilidad en agua a 20 °C de entre aproximadamente 20 mg/ml y aproximadamente 100 mg/ml, en donde la formulación de nicotina líquida tiene un contenido de agua superior o igual a aproximadamente 5 por ciento en peso y un contenido de solvente parcialmente soluble en agua, inmiscible en agua superior o igual a aproximadamente 2 por ciento en peso. Una formulación de nicotina líquida para su uso en un sistema generador de aerosol, la formulación de nicotina líquida comprende: agua; y uno o más solventes parcialmente solubles en agua, inmiscibles en agua que tienen un coeficiente de partición (log P) a 20 °C de entre aproximadamente 0.05 y aproximadamente 0.5, en donde la formulación de nicotina líquida tiene un contenido de agua superior o igual a aproximadamente 5 por ciento en peso y un contenido de solvente parcialmente soluble en agua, inmiscible en agua superior o igual a aproximadamente 2 por ciento en peso. Un cartucho para su uso en un sistema generador de aerosol, el cartucho contiene la formulación de nicotina líquida. Un sistema generador de aerosol que comprende la formulación de nicotina líquida y un atomizador configurado para generar un aerosol a partir de la formulación de nicotina líquida.
MX2021007625A 2018-12-31 2019-12-31 Formulacion de nicotina liquida que comprende un solvente parcialmente soluble en agua. MX2021007625A (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
EP18215976 2018-12-31
EP18215983 2018-12-31
EP18215966 2018-12-31
EP18215964 2018-12-31
EP18215969 2018-12-31
PCT/EP2019/087196 WO2020141178A1 (en) 2018-12-31 2019-12-31 Liquid nicotine formulation comprising partially water-soluble solvent

Publications (1)

Publication Number Publication Date
MX2021007625A true MX2021007625A (es) 2021-08-11

Family

ID=69104449

Family Applications (5)

Application Number Title Priority Date Filing Date
MX2021007623A MX2021007623A (es) 2018-12-31 2019-12-31 Formulacion liquida de nicotina que comprende solventes inmiscibles en agua.
MX2021007627A MX2021007627A (es) 2018-12-31 2019-12-31 Formulacion de nicotina liquida.
MX2021007624A MX2021007624A (es) 2018-12-31 2019-12-31 Formulacion de nicotina liquida.
MX2021007626A MX2021007626A (es) 2018-12-31 2019-12-31 Formulacion de nicotina liquida de baja viscosidad.
MX2021007625A MX2021007625A (es) 2018-12-31 2019-12-31 Formulacion de nicotina liquida que comprende un solvente parcialmente soluble en agua.

Family Applications Before (4)

Application Number Title Priority Date Filing Date
MX2021007623A MX2021007623A (es) 2018-12-31 2019-12-31 Formulacion liquida de nicotina que comprende solventes inmiscibles en agua.
MX2021007627A MX2021007627A (es) 2018-12-31 2019-12-31 Formulacion de nicotina liquida.
MX2021007624A MX2021007624A (es) 2018-12-31 2019-12-31 Formulacion de nicotina liquida.
MX2021007626A MX2021007626A (es) 2018-12-31 2019-12-31 Formulacion de nicotina liquida de baja viscosidad.

Country Status (8)

Country Link
US (5) US11992038B2 (es)
EP (5) EP3905898B1 (es)
JP (5) JP2022516896A (es)
KR (5) KR20210108384A (es)
CN (5) CN113163848B (es)
BR (5) BR112021010593A2 (es)
MX (5) MX2021007623A (es)
WO (5) WO2020141180A1 (es)

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IT202100027086A1 (it) * 2021-10-21 2023-04-21 Alberto Patarchi Erogatore portatile per il trattamento o la prevenzione di un’infezione o di una patologia causata da un virus
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Also Published As

Publication number Publication date
WO2020141184A1 (en) 2020-07-09
CN113163846A (zh) 2021-07-23
WO2020141180A1 (en) 2020-07-09
EP3905898B1 (en) 2024-05-08
JP2022516896A (ja) 2022-03-03
CN113163846B (zh) 2023-04-28
KR20210108390A (ko) 2021-09-02
WO2020141176A1 (en) 2020-07-09
MX2021007626A (es) 2021-08-11
CN113242696B (zh) 2023-04-28
EP3905900A1 (en) 2021-11-10
MX2021007627A (es) 2021-08-11
CN113163848A (zh) 2021-07-23
CN113242696A (zh) 2021-08-10
MX2021007624A (es) 2021-08-11
JP2022516149A (ja) 2022-02-24
EP3905897A1 (en) 2021-11-10
CN113163848B (zh) 2023-06-20
BR112021009726A2 (pt) 2021-08-17
EP3905901A1 (en) 2021-11-10
CN113163845B (zh) 2023-04-28
BR112021010593A2 (pt) 2021-08-24
KR20210108384A (ko) 2021-09-02
EP3905899A1 (en) 2021-11-10
BR112021010222A2 (pt) 2021-08-24
JP2022515983A (ja) 2022-02-24
KR20210108394A (ko) 2021-09-02
EP3905898C0 (en) 2024-05-08
WO2020141178A1 (en) 2020-07-09
EP3905900C0 (en) 2024-05-15
KR20210110314A (ko) 2021-09-07
BR112021010284A2 (pt) 2021-08-17
JP2022515021A (ja) 2022-02-17
BR112021010614A2 (pt) 2021-08-24
EP3905900B1 (en) 2024-05-15
KR20210109548A (ko) 2021-09-06
CN113163847A (zh) 2021-07-23
JP2022516895A (ja) 2022-03-03
MX2021007623A (es) 2021-08-11
EP3905898A1 (en) 2021-11-10
US20220079211A1 (en) 2022-03-17
CN113163847B (zh) 2023-01-10
US20220071270A1 (en) 2022-03-10
US20220053817A1 (en) 2022-02-24
US20220071269A1 (en) 2022-03-10
US20220079210A1 (en) 2022-03-17
US11992038B2 (en) 2024-05-28
CN113163845A (zh) 2021-07-23
WO2020141177A1 (en) 2020-07-09

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