MX2020003770A - Terapias de combinacion para tratar cancer. - Google Patents
Terapias de combinacion para tratar cancer.Info
- Publication number
- MX2020003770A MX2020003770A MX2020003770A MX2020003770A MX2020003770A MX 2020003770 A MX2020003770 A MX 2020003770A MX 2020003770 A MX2020003770 A MX 2020003770A MX 2020003770 A MX2020003770 A MX 2020003770A MX 2020003770 A MX2020003770 A MX 2020003770A
- Authority
- MX
- Mexico
- Prior art keywords
- treating cancer
- combination therapies
- therapies
- combination
- cancer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Abstract
La presente invención proporciona métodos de tratamiento para cáncer a través de terapia de combinación con un agente que inhibe la señalización de la proteína de muerte programada-1 (PD-1) y un agente que inhibe la señalización de poli [ADP-ribosa] polimerasa (PARP).
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762566398P | 2017-09-30 | 2017-09-30 | |
US201762578298P | 2017-10-27 | 2017-10-27 | |
US201862654024P | 2018-04-06 | 2018-04-06 | |
PCT/US2018/053542 WO2019067978A1 (en) | 2017-09-30 | 2018-09-28 | POLYTHERAPIES FOR THE TREATMENT OF CANCER |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2020003770A true MX2020003770A (es) | 2020-07-29 |
Family
ID=65903287
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020003770A MX2020003770A (es) | 2017-09-30 | 2018-09-28 | Terapias de combinacion para tratar cancer. |
Country Status (13)
Country | Link |
---|---|
US (1) | US11661453B2 (es) |
EP (1) | EP3697442A4 (es) |
JP (2) | JP2020536066A (es) |
KR (1) | KR20200086664A (es) |
CN (1) | CN111372607A (es) |
AU (1) | AU2018338901A1 (es) |
BR (1) | BR112020006286A2 (es) |
CA (1) | CA3076515A1 (es) |
IL (1) | IL273395A (es) |
MA (1) | MA50409A (es) |
MX (1) | MX2020003770A (es) |
SG (1) | SG11202002862RA (es) |
WO (1) | WO2019067978A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG11201903835WA (en) | 2016-11-01 | 2019-05-30 | Anaptysbio Inc | Antibodies directed against programmed death- 1 (pd-1) |
WO2018129559A1 (en) | 2017-01-09 | 2018-07-12 | Tesaro, Inc. | Methods of treating cancer with anti-pd-1 antibodies |
EA201992177A1 (ru) | 2017-03-27 | 2020-02-25 | Тесаро, Инк. | Композиции на основе нирапариба |
ES2926255T3 (es) | 2017-04-24 | 2022-10-24 | Tesaro Inc | Métodos de fabricación de niraparib |
JP2020520921A (ja) | 2017-05-18 | 2020-07-16 | テサロ, インコーポレイテッド | 癌を処置する併用療法 |
TW201927304A (zh) | 2017-09-26 | 2019-07-16 | 美商提薩羅有限公司 | 尼拉帕尼(niraparib)調配物 |
MX2020003770A (es) | 2017-09-30 | 2020-07-29 | Tesaro Inc | Terapias de combinacion para tratar cancer. |
MX2020003799A (es) | 2017-10-06 | 2020-11-06 | Tesaro Inc | Terapias de combinacion y usos de las mismas. |
EP4225383A1 (en) * | 2020-10-08 | 2023-08-16 | Kumquat Biosciences Inc. | Modulators of cell proliferation and uses thereof |
CN113234160B (zh) * | 2021-05-26 | 2022-05-27 | 广州爱思迈生物医药科技有限公司 | 一种抗pd-1抗体及其应用 |
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ES2059571T3 (es) | 1988-01-19 | 1994-11-16 | Takeda Chemical Industries Ltd | Fumagilina como agente angiostatico. |
ES2053890T3 (es) | 1988-09-01 | 1994-08-01 | Takeda Chemical Industries Ltd | Agente inhibidor de la angiogenesis. |
DK2206517T3 (da) | 2002-07-03 | 2023-11-06 | Ono Pharmaceutical Co | Immunpotentierende sammensætninger omfattende af anti-PD-L1-antistoffer |
US9707302B2 (en) | 2013-07-23 | 2017-07-18 | Immunomedics, Inc. | Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer |
AU2007232297B2 (en) | 2006-04-03 | 2012-09-20 | Msd Italia S.R.L. | Amide substituted indazole and benzotriazole derivatives as poly(ADP-ribose)polymerase (PARP) inhibitors |
PL2336120T3 (pl) | 2007-01-10 | 2014-12-31 | Msd Italia Srl | Kombinacje zawierające indazole podstawione grupą amidową jako inhibitory polimerazy poli(ADP-rybozy) (PARP) |
CN104945508B (zh) | 2007-06-18 | 2019-02-22 | 默沙东有限责任公司 | 针对人程序性死亡受体pd-1的抗体 |
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LT4209510T (lt) | 2008-12-09 | 2024-03-12 | F. Hoffmann-La Roche Ag | Anti-pd-l1 antikūnai ir jų panaudojimas t ląstelių funkcijos pagerinimui |
AR075239A1 (es) | 2009-02-04 | 2011-03-16 | Bipar Sciences Inc | Tratamiento del cancer de pulmon con un inhibidor de la parp en combinacion con un inhibidor de un factor de crecimiento. composicion farmaceutica. uso |
PT2504364T (pt) | 2009-11-24 | 2017-11-14 | Medimmune Ltd | Agentes de ligação direcionados contra b7-h1 |
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AU2011293635B2 (en) | 2010-08-24 | 2015-11-26 | Children's Medical Center Corporation | Methods for predicting anti-cancer response |
CA2742342A1 (en) | 2011-02-12 | 2012-08-12 | Baylor Research Institute | Msh3 expression status determines the responsiveness of cancer cells to the chemotherapeutic treatment with parp inhibitors and platinum drugs |
AU2012344260B2 (en) | 2011-11-28 | 2017-09-07 | Merck Patent Gmbh | Anti-PD-L1 antibodies and uses thereof |
NZ630278A (en) | 2012-06-07 | 2017-02-24 | Inst Curie | Methods for detecting inactivation of the homologous recombination pathway (brca1/2) in human tumors |
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MX2015015037A (es) * | 2013-05-02 | 2016-07-08 | Anaptysbio Inc | Anticuerpos dirigidos contra la proteina muerte programada-1 (pd-1). |
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WO2018129559A1 (en) | 2017-01-09 | 2018-07-12 | Tesaro, Inc. | Methods of treating cancer with anti-pd-1 antibodies |
MA47206A (fr) | 2017-01-09 | 2019-11-13 | Tesaro Inc | Méthodes de traitement du cancer au moyen d'anticorps anti-tim-3 |
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EA201992177A1 (ru) | 2017-03-27 | 2020-02-25 | Тесаро, Инк. | Композиции на основе нирапариба |
ES2926255T3 (es) | 2017-04-24 | 2022-10-24 | Tesaro Inc | Métodos de fabricación de niraparib |
CA3059468A1 (en) | 2017-04-27 | 2018-11-01 | Tesaro, Inc. | Antibody agents directed against lymphocyte activation gene-3 (lag-3) and uses thereof |
BR112019023591A2 (pt) | 2017-05-09 | 2020-05-26 | Tesaro, Inc. | Terapias de combinação para tratar câncer |
JP2020520921A (ja) | 2017-05-18 | 2020-07-16 | テサロ, インコーポレイテッド | 癌を処置する併用療法 |
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TW201927304A (zh) | 2017-09-26 | 2019-07-16 | 美商提薩羅有限公司 | 尼拉帕尼(niraparib)調配物 |
MX2020003770A (es) | 2017-09-30 | 2020-07-29 | Tesaro Inc | Terapias de combinacion para tratar cancer. |
MX2020003799A (es) | 2017-10-06 | 2020-11-06 | Tesaro Inc | Terapias de combinacion y usos de las mismas. |
SG11202006147SA (en) | 2017-12-27 | 2020-07-29 | Tesaro Inc | Methods of treating cancer |
SG11202007420PA (en) | 2018-02-05 | 2020-09-29 | Tesaro Inc | Pediatric niraparib formulations and pediatric treatment methods |
EA201992594A1 (ru) | 2018-03-26 | 2020-03-20 | Тесаро, Инк. | Комбинированные терапии для лечения рака |
US11970530B2 (en) | 2020-08-13 | 2024-04-30 | Astrazeneca Ab | Methods of treating homologous recombination deficient cancer |
-
2018
- 2018-09-28 MX MX2020003770A patent/MX2020003770A/es unknown
- 2018-09-28 SG SG11202002862RA patent/SG11202002862RA/en unknown
- 2018-09-28 AU AU2018338901A patent/AU2018338901A1/en active Pending
- 2018-09-28 US US16/651,920 patent/US11661453B2/en active Active
- 2018-09-28 CA CA3076515A patent/CA3076515A1/en active Pending
- 2018-09-28 WO PCT/US2018/053542 patent/WO2019067978A1/en active Application Filing
- 2018-09-28 CN CN201880075045.1A patent/CN111372607A/zh active Pending
- 2018-09-28 JP JP2020517921A patent/JP2020536066A/ja active Pending
- 2018-09-28 MA MA050409A patent/MA50409A/fr unknown
- 2018-09-28 KR KR1020207012178A patent/KR20200086664A/ko not_active Application Discontinuation
- 2018-09-28 BR BR112020006286-3A patent/BR112020006286A2/pt unknown
- 2018-09-28 EP EP18862422.5A patent/EP3697442A4/en active Pending
-
2020
- 2020-03-18 IL IL273395A patent/IL273395A/en unknown
-
2023
- 2023-03-09 JP JP2023036980A patent/JP2023076826A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP3697442A1 (en) | 2020-08-26 |
EP3697442A4 (en) | 2021-07-07 |
CN111372607A (zh) | 2020-07-03 |
AU2018338901A1 (en) | 2020-05-07 |
BR112020006286A2 (pt) | 2020-10-20 |
SG11202002862RA (en) | 2020-04-29 |
WO2019067978A1 (en) | 2019-04-04 |
JP2020536066A (ja) | 2020-12-10 |
IL273395A (en) | 2020-05-31 |
MA50409A (fr) | 2020-08-26 |
CA3076515A1 (en) | 2019-04-04 |
US11661453B2 (en) | 2023-05-30 |
JP2023076826A (ja) | 2023-06-02 |
KR20200086664A (ko) | 2020-07-17 |
US20200299387A1 (en) | 2020-09-24 |
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