MX2020002901A - Composiciones para la terapia con celulas t con receptores de antigeno quimerico y usos de las mismas. - Google Patents
Composiciones para la terapia con celulas t con receptores de antigeno quimerico y usos de las mismas.Info
- Publication number
- MX2020002901A MX2020002901A MX2020002901A MX2020002901A MX2020002901A MX 2020002901 A MX2020002901 A MX 2020002901A MX 2020002901 A MX2020002901 A MX 2020002901A MX 2020002901 A MX2020002901 A MX 2020002901A MX 2020002901 A MX2020002901 A MX 2020002901A
- Authority
- MX
- Mexico
- Prior art keywords
- compositions
- antigen receptor
- chimeric antigen
- cell therapy
- lipid
- Prior art date
Links
- 108010019670 Chimeric Antigen Receptors Proteins 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000002659 cell therapy Methods 0.000 title 1
- 239000003446 ligand Substances 0.000 abstract 2
- 150000002632 lipids Chemical class 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 229920001477 hydrophilic polymer Polymers 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
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- C07—ORGANIC CHEMISTRY
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- C07K16/3053—Skin, nerves, brain
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- C07K2319/00—Fusion polypeptide
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Abstract
La descripción presenta conjugados de ligando anfifílico que comprenden un ligando del receptor de antígeno quimérico (CAR) y un lípido. La descripción también presenta composiciones y métodos para usar los mismos, por ejemplo, para estimular la proliferación de células que expresan CAR.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762560588P | 2017-09-19 | 2017-09-19 | |
PCT/US2018/051764 WO2019060425A1 (en) | 2017-09-19 | 2018-09-19 | COMPOSITIONS FOR CHIMERIC ANTIGENIC RECEPTOR T CELL THERAPY AND USES THEREOF |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2020002901A true MX2020002901A (es) | 2020-07-22 |
Family
ID=64564947
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020002901A MX2020002901A (es) | 2017-09-19 | 2018-09-19 | Composiciones para la terapia con celulas t con receptores de antigeno quimerico y usos de las mismas. |
Country Status (9)
Country | Link |
---|---|
US (2) | US20200230221A1 (es) |
EP (1) | EP3684408A1 (es) |
JP (1) | JP2020535128A (es) |
KR (1) | KR20200055037A (es) |
CN (1) | CN111148533A (es) |
AU (1) | AU2018336791A1 (es) |
CA (1) | CA3076337A1 (es) |
MX (1) | MX2020002901A (es) |
WO (1) | WO2019060425A1 (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10704021B2 (en) | 2012-03-15 | 2020-07-07 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
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WO2016160721A1 (en) | 2015-03-27 | 2016-10-06 | President And Fellows Of Harvard College | Modified t cells and methods of making and using the same |
AU2016249005B2 (en) | 2015-04-17 | 2022-06-16 | Novartis Ag | Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells |
CN104894068A (zh) | 2015-05-04 | 2015-09-09 | 南京凯地生物科技有限公司 | 一种利用CRISPR/Cas9制备CAR-T细胞的方法 |
CN107921066A (zh) | 2015-05-28 | 2018-04-17 | 凯德药业股份有限公司 | 为t细胞疗法而调理患者的方法 |
SG10201912978PA (en) | 2015-07-21 | 2020-02-27 | Novartis Ag | Methods for improving the efficacy and expansion of immune cells |
EP3341410B1 (en) | 2015-08-24 | 2021-06-02 | Cellectis | Chimeric antigen receptors with integrated controllable functions |
JP2018527008A (ja) | 2015-09-17 | 2018-09-20 | ノバルティス アーゲー | 有効性が増強されたcar t細胞療法 |
CA3011248A1 (en) * | 2016-02-09 | 2017-08-17 | Bracco Suisse Sa | A recombinant chimeric protein for selectins targeting |
AU2017219859A1 (en) | 2016-02-16 | 2018-08-09 | Dana-Farber Cancer Institute, Inc. | Immunotherapy compositions and methods |
CN106480097A (zh) | 2016-10-13 | 2017-03-08 | 南京凯地生物科技有限公司 | 利用CRISPR/Cas9技术敲除人PD‑1基因构建可靶向MSLN新型CAR‑T细胞的方法及其应用 |
CN106399375A (zh) | 2016-08-31 | 2017-02-15 | 南京凯地生物科技有限公司 | 利用CRISPR/Cas9敲除人PD‑1基因构建靶向CD19CAR‑T细胞的方法 |
CN106755088A (zh) | 2016-11-11 | 2017-05-31 | 广东万海细胞生物科技有限公司 | 一种自体car‑t细胞制备方法及应用 |
CN106591363A (zh) | 2016-11-11 | 2017-04-26 | 广东万海细胞生物科技有限公司 | 一种通用型异体car‑t细胞制备方法及应用 |
-
2018
- 2018-09-19 US US16/644,893 patent/US20200230221A1/en not_active Abandoned
- 2018-09-19 JP JP2020515969A patent/JP2020535128A/ja active Pending
- 2018-09-19 EP EP18811951.5A patent/EP3684408A1/en active Pending
- 2018-09-19 WO PCT/US2018/051764 patent/WO2019060425A1/en unknown
- 2018-09-19 CA CA3076337A patent/CA3076337A1/en active Pending
- 2018-09-19 MX MX2020002901A patent/MX2020002901A/es unknown
- 2018-09-19 KR KR1020207010759A patent/KR20200055037A/ko not_active Application Discontinuation
- 2018-09-19 AU AU2018336791A patent/AU2018336791A1/en active Pending
- 2018-09-19 CN CN201880061030.XA patent/CN111148533A/zh active Pending
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2023
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CN111148533A (zh) | 2020-05-12 |
RU2020113680A3 (es) | 2021-12-29 |
RU2020113680A (ru) | 2021-10-20 |
CA3076337A1 (en) | 2019-03-28 |
US20200230221A1 (en) | 2020-07-23 |
KR20200055037A (ko) | 2020-05-20 |
EP3684408A1 (en) | 2020-07-29 |
JP2020535128A (ja) | 2020-12-03 |
WO2019060425A1 (en) | 2019-03-28 |
AU2018336791A1 (en) | 2020-03-12 |
US20240082373A1 (en) | 2024-03-14 |
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