MX2019009020A - Metodo para reducir la neutropenia. - Google Patents
Metodo para reducir la neutropenia.Info
- Publication number
- MX2019009020A MX2019009020A MX2019009020A MX2019009020A MX2019009020A MX 2019009020 A MX2019009020 A MX 2019009020A MX 2019009020 A MX2019009020 A MX 2019009020A MX 2019009020 A MX2019009020 A MX 2019009020A MX 2019009020 A MX2019009020 A MX 2019009020A
- Authority
- MX
- Mexico
- Prior art keywords
- reducing
- neutropenia
- reducing neutropenia
- plinabulin
- disclosed
- Prior art date
Links
- 208000004235 neutropenia Diseases 0.000 title abstract 3
- UNRCMCRRFYFGFX-TYPNBTCFSA-N plinabulin Chemical compound N1C=NC(\C=C/2C(NC(=C\C=3C=CC=CC=3)/C(=O)N\2)=O)=C1C(C)(C)C UNRCMCRRFYFGFX-TYPNBTCFSA-N 0.000 abstract 2
- 229950011498 plinabulin Drugs 0.000 abstract 2
- ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 abstract 1
- 229960003668 docetaxel Drugs 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Management, Administration, Business Operations System, And Electronic Commerce (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Se describen en la presente plinabulina y el uso para reducir la neutropenia. Algunas modalidades se relacionan con la reducción de la neutropenia inducida por docetaxel usando plinabulina.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762453375P | 2017-02-01 | 2017-02-01 | |
US201862621533P | 2018-01-24 | 2018-01-24 | |
PCT/US2018/016498 WO2018144764A1 (en) | 2017-02-01 | 2018-02-01 | Method of reducing neutropenia |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2019009020A true MX2019009020A (es) | 2019-11-12 |
Family
ID=63040105
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019009020A MX2019009020A (es) | 2017-02-01 | 2018-02-01 | Metodo para reducir la neutropenia. |
MX2022010805A MX2022010805A (es) | 2017-02-01 | 2019-07-30 | Metodo para reducir la neutropenia. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2022010805A MX2022010805A (es) | 2017-02-01 | 2019-07-30 | Metodo para reducir la neutropenia. |
Country Status (15)
Country | Link |
---|---|
US (2) | US11400086B2 (es) |
EP (1) | EP3576733A4 (es) |
JP (2) | JP2020514412A (es) |
KR (1) | KR20190109479A (es) |
CN (1) | CN110381938A (es) |
AU (1) | AU2018217120B2 (es) |
BR (1) | BR112019015974A2 (es) |
CA (1) | CA3052190A1 (es) |
CL (1) | CL2019002127A1 (es) |
IL (1) | IL268305B1 (es) |
MX (2) | MX2019009020A (es) |
MY (1) | MY201811A (es) |
PH (1) | PH12019501763A1 (es) |
SG (1) | SG11201907023UA (es) |
WO (1) | WO2018144764A1 (es) |
Families Citing this family (14)
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CN107530340B (zh) | 2015-03-06 | 2021-06-08 | 大连万春布林医药有限公司 | 治疗脑肿瘤的方法 |
RU2736045C2 (ru) | 2015-03-06 | 2020-11-11 | Бейондспринг Фармасьютикалс, Инк. | Способ лечения рака, ассоциированного с мутацией ras |
US10155748B2 (en) | 2015-07-13 | 2018-12-18 | Beyondspring Pharmaceuticals, Inc. | Plinabulin compositions |
NZ744854A (en) | 2016-02-08 | 2020-01-31 | Beyondspring Pharmaceuticals Inc | Compositions containing tucaresol or its analogs |
KR20190015361A (ko) | 2016-06-06 | 2019-02-13 | 비욘드스프링 파마수티컬스, 인코포레이티드. | 호중구감소증을 줄이는 조성물 및 방법 |
WO2018129381A1 (en) | 2017-01-06 | 2018-07-12 | Beyondspring Pharmaceuticals, Inc. | Tubulin binding compounds and therapeutic use thereof |
KR20190109479A (ko) | 2017-02-01 | 2019-09-25 | 비욘드스프링 파마수티컬스, 인코포레이티드. | 호중구감소증의 감소 방법 |
BR112020014960A2 (pt) | 2018-01-24 | 2020-12-22 | Beyondspring Pharmaceuticals, Inc. | Composição e método para redução de trombocitopenia |
JP2021512121A (ja) * | 2018-02-01 | 2021-05-13 | ビヨンドスプリング ファーマシューティカルズ,インコーポレイテッド | プリナブリンおよびg−csf製剤の投与による化学療法誘発性好中球減少症を軽減するための組成物および方法 |
US11684655B2 (en) | 2019-05-31 | 2023-06-27 | Spectrum Pharmaceuticals, Inc. | Methods of treating neutorpenia using G-CSF protein complex |
US11267858B2 (en) | 2019-05-31 | 2022-03-08 | Spectrum Pharmaceuticals, Inc. | Methods of treatment using G-CSF protein complex |
WO2021076485A1 (en) * | 2019-10-15 | 2021-04-22 | Beyondspring Pharmaceuticals, Inc. | Methods and compositions for treating iron disorders |
WO2022040073A1 (en) * | 2020-08-18 | 2022-02-24 | Spectrum Pharmaceuticals, Inc. | Novel methods of treating neutropenia using g-csf protein complex |
WO2023274316A1 (zh) * | 2021-06-29 | 2023-01-05 | 深圳华泓海洋生物医药有限公司 | 氘代普那布林在制备治疗中性粒细胞减少症药物中的应用 |
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2018
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- 2018-02-01 US US16/482,547 patent/US11400086B2/en active Active
- 2018-02-01 SG SG11201907023UA patent/SG11201907023UA/en unknown
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- 2018-02-01 CA CA3052190A patent/CA3052190A1/en active Pending
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- 2018-02-01 MY MYPI2019004361A patent/MY201811A/en unknown
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2022
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WO2018144764A1 (en) | 2018-08-09 |
AU2018217120A1 (en) | 2019-08-15 |
EP3576733A1 (en) | 2019-12-11 |
JP2022191484A (ja) | 2022-12-27 |
MY201811A (en) | 2024-03-19 |
AU2018217120B2 (en) | 2024-02-08 |
NZ755858A (en) | 2021-11-26 |
IL268305B1 (en) | 2024-04-01 |
SG11201907023UA (en) | 2019-08-27 |
US11400086B2 (en) | 2022-08-02 |
MX2022010805A (es) | 2022-09-27 |
RU2019125489A (ru) | 2021-03-02 |
CA3052190A1 (en) | 2018-08-09 |
US20220378784A1 (en) | 2022-12-01 |
CL2019002127A1 (es) | 2019-12-13 |
US20200038395A1 (en) | 2020-02-06 |
CN110381938A (zh) | 2019-10-25 |
EP3576733A4 (en) | 2020-11-25 |
KR20190109479A (ko) | 2019-09-25 |
RU2019125489A3 (es) | 2021-10-25 |
PH12019501763A1 (en) | 2020-03-16 |
JP2020514412A (ja) | 2020-05-21 |
IL268305A (en) | 2019-09-26 |
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