MX2017008904A - Biomarcadores basados en sangre para diagnosticar enfermedad de arteria coronaria ateroesclerotica. - Google Patents

Biomarcadores basados en sangre para diagnosticar enfermedad de arteria coronaria ateroesclerotica.

Info

Publication number
MX2017008904A
MX2017008904A MX2017008904A MX2017008904A MX2017008904A MX 2017008904 A MX2017008904 A MX 2017008904A MX 2017008904 A MX2017008904 A MX 2017008904A MX 2017008904 A MX2017008904 A MX 2017008904A MX 2017008904 A MX2017008904 A MX 2017008904A
Authority
MX
Mexico
Prior art keywords
artery disease
coronary artery
blood based
atherosclerotic coronary
based biomarkers
Prior art date
Application number
MX2017008904A
Other languages
English (en)
Inventor
Voros Szilard
O Brown Bradley
B Marvasty Idean
Original Assignee
Global Genomics Group Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Global Genomics Group Llc filed Critical Global Genomics Group Llc
Publication of MX2017008904A publication Critical patent/MX2017008904A/es

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/492Determining multiple analytes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37Coumarins, e.g. psoralen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • A61K31/612Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806Determination of free amino acids
    • G01N33/6812Assays for specific amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00Chemical aspects of mass spectrometric analysis of biological material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/32Cardiovascular disorders
    • G01N2800/324Coronary artery diseases, e.g. angina pectoris, myocardial infarction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/50Determining the risk of developing a disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/60Complex ways of combining multiple protein biomarkers for diagnosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ecology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

Abstract

La invención, en algunos aspectos, se relaciona con métodos para evaluar a un sujeto humano para determinar si presenta enfermedad de arteria coronaria ateroesclerótica (ASCAD) o si tiene una placa ateroesclerótica coronaria. En algunos aspectos, la invención se relaciona con métodos y kits útiles para diagnosticar, clasificar, caracterizar y tratar CAD ateroesclerótica y/o una placa ateroesclerótica coronaria.
MX2017008904A 2015-01-09 2016-01-08 Biomarcadores basados en sangre para diagnosticar enfermedad de arteria coronaria ateroesclerotica. MX2017008904A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562101445P 2015-01-09 2015-01-09
PCT/US2016/012725 WO2016112337A1 (en) 2015-01-09 2016-01-08 Blood based biomarkers for diagnosing atherosclerotic coronary artery disease

Publications (1)

Publication Number Publication Date
MX2017008904A true MX2017008904A (es) 2018-02-09

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017008904A MX2017008904A (es) 2015-01-09 2016-01-08 Biomarcadores basados en sangre para diagnosticar enfermedad de arteria coronaria ateroesclerotica.

Country Status (12)

Country Link
US (2) US10254272B2 (es)
EP (3) EP3650852B1 (es)
KR (1) KR20170102983A (es)
CN (2) CN107427221B (es)
CA (1) CA2973116C (es)
HU (2) HUE047951T2 (es)
IL (1) IL253179A0 (es)
MX (1) MX2017008904A (es)
SG (1) SG11201705444QA (es)
TW (2) TWI610079B (es)
WO (1) WO2016112337A1 (es)
ZA (1) ZA201705032B (es)

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CN111983160B (zh) * 2020-08-14 2022-08-09 中元伯瑞生物科技(珠海横琴)有限公司 神经酸在治疗脑卒中药物中的应用
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Also Published As

Publication number Publication date
US20190391131A1 (en) 2019-12-26
TWI610079B (zh) 2018-01-01
KR20170102983A (ko) 2017-09-12
EP3650852A1 (en) 2020-05-13
EP3242588A1 (en) 2017-11-15
US20160202239A1 (en) 2016-07-14
CA2973116C (en) 2023-08-15
TW201802471A (zh) 2018-01-16
US10254272B2 (en) 2019-04-09
HUE056203T2 (hu) 2022-01-28
TWI690707B (zh) 2020-04-11
EP3967217A1 (en) 2022-03-16
CN113156096A (zh) 2021-07-23
CN107427221B (zh) 2021-03-09
EP3242588A4 (en) 2018-10-17
ZA201705032B (en) 2019-09-25
EP3650852B1 (en) 2021-08-18
IL253179A0 (en) 2017-08-31
EP3242588B1 (en) 2019-10-16
HUE047951T2 (hu) 2020-05-28
TW201725387A (zh) 2017-07-16
SG11201705444QA (en) 2017-07-28
CA2973116A1 (en) 2016-07-14
CN107427221A (zh) 2017-12-01
WO2016112337A1 (en) 2016-07-14

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