MX2016014695A - Combinaciones de bromuro de tiotropio, formoterol y budesonida para el tratamiento de enfermedad pulmonar obstructiva cronica. - Google Patents
Combinaciones de bromuro de tiotropio, formoterol y budesonida para el tratamiento de enfermedad pulmonar obstructiva cronica.Info
- Publication number
- MX2016014695A MX2016014695A MX2016014695A MX2016014695A MX2016014695A MX 2016014695 A MX2016014695 A MX 2016014695A MX 2016014695 A MX2016014695 A MX 2016014695A MX 2016014695 A MX2016014695 A MX 2016014695A MX 2016014695 A MX2016014695 A MX 2016014695A
- Authority
- MX
- Mexico
- Prior art keywords
- copd
- treatment
- formoterol
- budesonide
- combinations
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, ***e
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Abstract
Esta invención provee un producto de combinación que comprende una composición de antagonista muscarínico de acción prolongada inhalable (LAMA) para usarse en el tratamiento a largo plazo de EPOC combinada con una composición de dosis fija inhalable que comprende budesonida y formoterol o una sal farmacéuticamente aceptable del mismo para administración pro re nata (p.r.n.) como una medicamento de rescate para el tratamiento de las exacerbaciones agudas de EPOC.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1408387.7A GB201408387D0 (en) | 2014-05-12 | 2014-05-12 | Treatment of respiratory disorders |
PCT/EP2015/060256 WO2015173153A1 (en) | 2014-05-12 | 2015-05-08 | Combinations of tiotropium bromide, formoterol and budesonide for the treatment of copd |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2016014695A true MX2016014695A (es) | 2017-05-04 |
Family
ID=51032625
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016014696A MX2016014696A (es) | 2014-05-12 | 2015-05-08 | Combinaciones de formoterol y budesonida para el tratamiento de enfermedad pulmonar obstructiva cronica. |
MX2016014695A MX2016014695A (es) | 2014-05-12 | 2015-05-08 | Combinaciones de bromuro de tiotropio, formoterol y budesonida para el tratamiento de enfermedad pulmonar obstructiva cronica. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016014696A MX2016014696A (es) | 2014-05-12 | 2015-05-08 | Combinaciones de formoterol y budesonida para el tratamiento de enfermedad pulmonar obstructiva cronica. |
Country Status (17)
Country | Link |
---|---|
US (2) | US20170202858A1 (es) |
EP (2) | EP3142653A1 (es) |
JP (4) | JP2017515835A (es) |
KR (2) | KR20170003601A (es) |
CN (2) | CN106488770A (es) |
AR (2) | AR100369A1 (es) |
AU (2) | AU2015261104A1 (es) |
BR (2) | BR112016026369A2 (es) |
CA (2) | CA2948574A1 (es) |
CL (1) | CL2016002848A1 (es) |
EA (2) | EA201692278A1 (es) |
GB (1) | GB201408387D0 (es) |
IL (2) | IL248875A0 (es) |
MX (2) | MX2016014696A (es) |
PE (1) | PE20170073A1 (es) |
UA (2) | UA119773C2 (es) |
WO (2) | WO2015173153A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104758294A (zh) * | 2014-12-17 | 2015-07-08 | 广州呼吸疾病研究所 | 用于copd、哮喘治疗的吸入药物组合物及其制备方法 |
WO2017108917A1 (en) * | 2015-12-22 | 2017-06-29 | Astrazeneca Ab | Pharmaceutical compositions for use in the treatment of chronic obstructive pulmonary disease |
CN106466322A (zh) * | 2016-08-25 | 2017-03-01 | 杭州百诚医药科技股份有限公司 | 一种以布***和噻托溴铵为活性成分的复方制剂 |
WO2018071435A1 (en) * | 2016-10-11 | 2018-04-19 | Microdose Therapeutx, Inc. | Inhaler and methods of use thereof |
WO2019142214A1 (en) | 2018-01-19 | 2019-07-25 | Cipla Limited | Pharmaceutical composition comprising tiotropium for inhalation |
CA3091804A1 (en) * | 2018-02-23 | 2019-08-29 | Microdose Therapeutx, Inc. | Inhaler and methods of use thereof |
CN116077471A (zh) * | 2021-11-08 | 2023-05-09 | 上海臣邦医药科技股份有限公司 | 一种供吸入用的粉雾剂组合物及其制备方法和应用 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1086697A2 (en) * | 1991-12-18 | 2001-03-28 | AstraZeneca AB | New combination of formoterol and budesonide |
SK282826B6 (sk) * | 1991-12-18 | 2002-12-03 | Aktiebolaget Astra | Farmaceutická kompozícia na podávanie inhaláciou s obsahom formoterolu a budesonidu a jej použitie |
SE9703407D0 (sv) * | 1997-09-19 | 1997-09-19 | Astra Ab | New use |
SE9802073D0 (sv) * | 1998-06-11 | 1998-06-11 | Astra Ab | New use |
DE10130371A1 (de) * | 2001-06-23 | 2003-01-02 | Boehringer Ingelheim Pharma | Neue Arzneimittelkompositionen auf der Basis von Anticholinergika, Corticosteroiden und Betamimetika |
UA80123C2 (en) * | 2002-04-09 | 2007-08-27 | Boehringer Ingelheim Pharma | Inhalation kit comprising inhalable powder of tiotropium |
SE526509C2 (sv) * | 2003-06-19 | 2005-09-27 | Microdrug Ag | Kombinerade doser av formoterol och budesonid separerade på en gemensam dosbädd |
US20070293460A1 (en) * | 2005-10-31 | 2007-12-20 | Richie's Pharmacy And Medical Supply, Incorporated | Delivery of a combination therapy for asthma and chronic obstructive pulmonary disease |
US20090291146A1 (en) * | 2006-08-09 | 2009-11-26 | Glaxo Group Limited | Process for manufacturing lactose |
KR20090121338A (ko) * | 2007-02-19 | 2009-11-25 | 씨아이피엘에이 엘티디. | 두 개 이상의 기관지확장제 또는 기관지확장제와 코르티코스테로이드의 약제학적 조합 |
JP2010539182A (ja) * | 2007-09-12 | 2010-12-16 | グラクソ グループ リミテッド | 治療剤の新規組み合わせ |
TR201000680A2 (tr) * | 2010-01-29 | 2011-08-22 | B�Lg�� Mahmut | Tiotropyum, formoterol ve budesonid içeren farmasötik bileşimler |
WO2011131663A1 (en) * | 2010-04-21 | 2011-10-27 | Chiesi Farmaceutici S.P.A. | "process for providing particles with reduced electrostatic charges" |
BR112013001119A2 (pt) * | 2010-07-16 | 2016-05-24 | Cipla Ltd | composição farmacêutica, processo para fabricar uma composição farmacêutica, uso de r(+)budesonida e um broncodilatador, e método de profilaxia ou tratamento de uma doença respiratória, inflamatória ou obstrutiva das vias aéreas |
JOP20120023B1 (ar) * | 2011-02-04 | 2022-03-14 | Novartis Ag | صياغات مساحيق جافة من جسيمات تحتوي على واحد أو اثنين من المواد الفعالة لعلاج امراض ممرات الهواء الانسدادية او الالتهابية |
RU2460547C1 (ru) * | 2011-04-08 | 2012-09-10 | Валерий Феофанович Ушаков | Способ пролонгированной профилактики холодового бронхоспазма у больных с "микст-патологией" |
WO2014007770A2 (en) * | 2012-07-05 | 2014-01-09 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Inhalation compositions comprising corticosteroid and sorbitol |
ITMI20130571A1 (it) * | 2013-04-10 | 2014-10-11 | Zambon Spa | Composizione farmaceutica contenente budesonide e formoterolo |
-
2014
- 2014-05-12 GB GBGB1408387.7A patent/GB201408387D0/en not_active Ceased
-
2015
- 2015-05-08 EA EA201692278A patent/EA201692278A1/ru unknown
- 2015-05-08 JP JP2016567354A patent/JP2017515835A/ja active Pending
- 2015-05-08 KR KR1020167033456A patent/KR20170003601A/ko not_active Application Discontinuation
- 2015-05-08 BR BR112016026369-3A patent/BR112016026369A2/pt not_active Application Discontinuation
- 2015-05-08 MX MX2016014696A patent/MX2016014696A/es unknown
- 2015-05-08 JP JP2016567345A patent/JP2017515833A/ja active Pending
- 2015-05-08 WO PCT/EP2015/060256 patent/WO2015173153A1/en active Application Filing
- 2015-05-08 AU AU2015261104A patent/AU2015261104A1/en not_active Abandoned
- 2015-05-08 US US15/310,133 patent/US20170202858A1/en not_active Abandoned
- 2015-05-08 AU AU2015261103A patent/AU2015261103A1/en not_active Abandoned
- 2015-05-08 UA UAA201612510A patent/UA119773C2/uk unknown
- 2015-05-08 CA CA2948574A patent/CA2948574A1/en not_active Abandoned
- 2015-05-08 WO PCT/EP2015/060257 patent/WO2015173154A1/en active Application Filing
- 2015-05-08 PE PE2016002160A patent/PE20170073A1/es unknown
- 2015-05-08 BR BR112016026371-5A patent/BR112016026371A2/pt not_active Application Discontinuation
- 2015-05-08 CN CN201580024895.5A patent/CN106488770A/zh active Pending
- 2015-05-08 KR KR1020167033449A patent/KR20170003600A/ko not_active Application Discontinuation
- 2015-05-08 CA CA2948553A patent/CA2948553A1/en not_active Abandoned
- 2015-05-08 EP EP15722174.8A patent/EP3142653A1/en not_active Withdrawn
- 2015-05-08 MX MX2016014695A patent/MX2016014695A/es unknown
- 2015-05-08 UA UAA201612511A patent/UA119774C2/uk unknown
- 2015-05-08 CN CN201580027124.1A patent/CN106470700A/zh active Pending
- 2015-05-08 EA EA201692276A patent/EA201692276A1/ru unknown
- 2015-05-08 US US15/310,130 patent/US20170209464A1/en not_active Abandoned
- 2015-05-08 EP EP15723675.3A patent/EP3142654A1/en not_active Withdrawn
- 2015-05-11 AR ARP150101432A patent/AR100369A1/es unknown
- 2015-05-11 AR ARP150101431A patent/AR100368A1/es unknown
-
2016
- 2016-11-09 CL CL2016002848A patent/CL2016002848A1/es unknown
- 2016-11-09 IL IL248875A patent/IL248875A0/en unknown
- 2016-11-09 IL IL248874A patent/IL248874A0/en unknown
-
2019
- 2019-10-11 JP JP2019187349A patent/JP2020023536A/ja not_active Withdrawn
- 2019-10-11 JP JP2019187350A patent/JP2020023537A/ja not_active Withdrawn
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