SG11201602540XA - Biomarkers for systemic lupus erythematosus disease activity, and intensity and flare - Google Patents
Biomarkers for systemic lupus erythematosus disease activity, and intensity and flareInfo
- Publication number
- SG11201602540XA SG11201602540XA SG11201602540XA SG11201602540XA SG11201602540XA SG 11201602540X A SG11201602540X A SG 11201602540XA SG 11201602540X A SG11201602540X A SG 11201602540XA SG 11201602540X A SG11201602540X A SG 11201602540XA SG 11201602540X A SG11201602540X A SG 11201602540XA
- Authority
- SG
- Singapore
- Prior art keywords
- biomarkers
- flare
- intensity
- lupus erythematosus
- systemic lupus
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/10—Musculoskeletal or connective tissue disorders
- G01N2800/101—Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
- G01N2800/104—Lupus erythematosus [SLE]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rehabilitation Therapy (AREA)
- Rheumatology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361886189P | 2013-10-03 | 2013-10-03 | |
PCT/US2014/058812 WO2015051110A1 (en) | 2013-10-03 | 2014-10-02 | Biomarkers for systemic lupus erythematosus disease activity, and intensity and flare |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201602540XA true SG11201602540XA (en) | 2016-04-28 |
Family
ID=52777119
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201602540XA SG11201602540XA (en) | 2013-10-03 | 2014-10-02 | Biomarkers for systemic lupus erythematosus disease activity, and intensity and flare |
Country Status (9)
Country | Link |
---|---|
US (4) | US20150098940A1 (en) |
EP (1) | EP3052193B1 (en) |
AU (1) | AU2014329535B2 (en) |
BR (1) | BR112016007391A2 (en) |
CA (1) | CA2925004C (en) |
IL (1) | IL244734A0 (en) |
MX (1) | MX2016004283A (en) |
SG (1) | SG11201602540XA (en) |
WO (1) | WO2015051110A1 (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG11201602540XA (en) * | 2013-10-03 | 2016-04-28 | Oklahoma Med Res Found | Biomarkers for systemic lupus erythematosus disease activity, and intensity and flare |
WO2016054738A1 (en) * | 2014-10-07 | 2016-04-14 | University Health Network | Urinary biomarkers for sle and lupus nephritis |
EP3835787A1 (en) * | 2016-02-16 | 2021-06-16 | CellTrend GmbH | Anti-cxc chemokine receptor antibodies and c-x-c chemokines for the prognosis of acute graft-versus-host disease |
AU2018213315A1 (en) * | 2017-01-26 | 2019-07-25 | Oklahoma Medical Research Foundation | Biomarkers for systemic lupus erythematosus disease activity, and intensity and flare |
US20180364229A1 (en) * | 2017-06-16 | 2018-12-20 | Oklahoma Medical Research Foundation | Biomarkers for Assessing Risk of Transitioning to Systemic Lupus Erythematosus Classification and Disease Pathogenesis |
JP6944700B2 (en) * | 2017-10-02 | 2021-10-06 | 学校法人 川崎学園 | How to test for autoimmune disorders |
KR102074798B1 (en) * | 2018-06-15 | 2020-02-07 | 코아스템(주) | Biomarker for treatment of autoimmune diseases, diagnostic kit and the therapeutic use thereof |
AU2019360758A1 (en) * | 2018-10-18 | 2021-05-20 | Oklahoma Medical Research Foundation | Biomarkers for a systemic lupus erythematosus (SLE) disease activity immune index that characterizes disease activity |
WO2021041299A1 (en) * | 2019-08-29 | 2021-03-04 | St. Jude Children's Research Hospital, Inc. | Method and kit for determining benefit of chemotherapy |
US20220344002A1 (en) * | 2019-09-20 | 2022-10-27 | Oklahoma Medical Research Foundation | Soluble mediators for predicting systemic lupus erythematosus activity events |
US11367521B1 (en) | 2020-12-29 | 2022-06-21 | Kpn Innovations, Llc. | System and method for generating a mesodermal outline nourishment program |
Family Cites Families (91)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL154598B (en) | 1970-11-10 | 1977-09-15 | Organon Nv | PROCEDURE FOR DETERMINING AND DETERMINING LOW MOLECULAR COMPOUNDS AND PROTEINS THAT CAN SPECIFICALLY BIND THESE COMPOUNDS AND TEST PACKAGING. |
US3817837A (en) | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
US3939350A (en) | 1974-04-29 | 1976-02-17 | Board Of Trustees Of The Leland Stanford Junior University | Fluorescent immunoassay employing total reflection for activation |
US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
US4277437A (en) | 1978-04-05 | 1981-07-07 | Syva Company | Kit for carrying out chemically induced fluorescence immunoassay |
US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
US4957858A (en) | 1986-04-16 | 1990-09-18 | The Salk Instute For Biological Studies | Replicative RNA reporter systems |
US4883750A (en) | 1984-12-13 | 1989-11-28 | Applied Biosystems, Inc. | Detection of specific sequences in nucleic acids |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
ATE88761T1 (en) | 1986-01-10 | 1993-05-15 | Amoco Corp | COMPETITIVE HOMOGENEOUS TEST. |
US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
AU622104B2 (en) | 1987-03-11 | 1992-04-02 | Sangtec Molecular Diagnostics Ab | Method of assaying of nucleic acids, a reagent combination and kit therefore |
IL86724A (en) | 1987-06-19 | 1995-01-24 | Siska Diagnostics Inc | Method and kits for the amplification and detection of nucleic acid sequences |
DE68908054T2 (en) | 1988-01-21 | 1994-03-10 | Genentech Inc | REINFORCEMENT AND DETECTION OF NUCLEIC ACID SEQUENCES. |
CA1340807C (en) | 1988-02-24 | 1999-11-02 | Lawrence T. Malek | Nucleic acid amplification process |
EP0365627B1 (en) | 1988-03-24 | 1993-12-22 | University Of Iowa Research Foundation | Catalytic hybridization systems for the detection of nucleic acid sequences based on their activity as cofactors in catalytic reactions in which a complementary labeled nucleic acid probe is cleaved |
US5932413A (en) | 1988-04-01 | 1999-08-03 | Celebuski; Joseph Eugene | DNA probe assay using neutrally charged probe strands |
US5700637A (en) | 1988-05-03 | 1997-12-23 | Isis Innovation Limited | Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays |
US5858652A (en) | 1988-08-30 | 1999-01-12 | Abbott Laboratories | Detection and amplification of target nucleic acid sequences |
GB8822228D0 (en) | 1988-09-21 | 1988-10-26 | Southern E M | Support-bound oligonucleotides |
CA1339731C (en) | 1988-10-12 | 1998-03-17 | Charles T. Caskey | Multiplex genomic dna amplification for deletion detection |
US4932207A (en) | 1988-12-28 | 1990-06-12 | Sundstrand Corporation | Segmented seal plate for a turbine engine |
US5856092A (en) | 1989-02-13 | 1999-01-05 | Geneco Pty Ltd | Detection of a nucleic acid sequence or a change therein |
US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
US5527681A (en) | 1989-06-07 | 1996-06-18 | Affymax Technologies N.V. | Immobilized molecular synthesis of systematically substituted compounds |
US5242974A (en) | 1991-11-22 | 1993-09-07 | Affymax Technologies N.V. | Polymer reversal on solid surfaces |
US5424186A (en) | 1989-06-07 | 1995-06-13 | Affymax Technologies N.V. | Very large scale immobilized polymer synthesis |
DE3924454A1 (en) | 1989-07-24 | 1991-02-07 | Cornelis P Prof Dr Hollenberg | THE APPLICATION OF DNA AND DNA TECHNOLOGY FOR THE CONSTRUCTION OF NETWORKS FOR USE IN CHIP CONSTRUCTION AND CHIP PRODUCTION (DNA CHIPS) |
US5645987A (en) | 1990-09-21 | 1997-07-08 | Amgen Inc. | Enzymatic synthesis of oligonucleotides |
US5846717A (en) | 1996-01-24 | 1998-12-08 | Third Wave Technologies, Inc. | Detection of nucleic acid sequences by invader-directed cleavage |
IL103674A0 (en) | 1991-11-19 | 1993-04-04 | Houston Advanced Res Center | Method and apparatus for molecule detection |
US5846708A (en) | 1991-11-19 | 1998-12-08 | Massachusetts Institiute Of Technology | Optical and electrical methods and apparatus for molecule detection |
US5384261A (en) | 1991-11-22 | 1995-01-24 | Affymax Technologies N.V. | Very large scale immobilized polymer synthesis using mechanically directed flow paths |
US5412087A (en) | 1992-04-24 | 1995-05-02 | Affymax Technologies N.V. | Spatially-addressable immobilization of oligonucleotides and other biological polymers on surfaces |
WO1993020235A1 (en) | 1992-04-01 | 1993-10-14 | The Johns Hopkins University School Of Medicine | Methods of detecting mammalian nucleic acids isolated from stool specimen and reagents therefor |
US5843640A (en) | 1992-06-19 | 1998-12-01 | Northwestern University | Method of simultaneously detecting amplified nucleic acid sequences and cellular antigens in cells |
US5861244A (en) | 1992-10-29 | 1999-01-19 | Profile Diagnostic Sciences, Inc. | Genetic sequence assay using DNA triple strand formation |
US5554501A (en) | 1992-10-29 | 1996-09-10 | Beckman Instruments, Inc. | Biopolymer synthesis using surface activated biaxially oriented polypropylene |
US5658751A (en) | 1993-04-13 | 1997-08-19 | Molecular Probes, Inc. | Substituted unsymmetrical cyanine dyes with selected permeability |
US5279721A (en) | 1993-04-22 | 1994-01-18 | Peter Schmid | Apparatus and method for an automated electrophoresis system |
GB9311386D0 (en) | 1993-06-02 | 1993-07-21 | Pna Diagnostics As | Nucleic acid analogue assay procedures |
US5846709A (en) | 1993-06-15 | 1998-12-08 | Imclone Systems Incorporated | Chemical process for amplifying and detecting nucleic acid sequences |
FR2708288B1 (en) | 1993-07-26 | 1995-09-01 | Bio Merieux | Method for amplification of nucleic acids by transcription using displacement, reagents and necessary for the implementation of this method. |
US5472672A (en) | 1993-10-22 | 1995-12-05 | The Board Of Trustees Of The Leland Stanford Junior University | Apparatus and method for polymer synthesis using arrays |
US5429807A (en) | 1993-10-28 | 1995-07-04 | Beckman Instruments, Inc. | Method and apparatus for creating biopolymer arrays on a solid support surface |
US5925517A (en) | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
EP0663447B1 (en) | 1993-12-28 | 2003-07-09 | Eiken Chemical Co., Ltd. | Method of detecting a specific polynucleotide |
US5928905A (en) | 1995-04-18 | 1999-07-27 | Glaxo Group Limited | End-complementary polymerase reaction |
US5571639A (en) | 1994-05-24 | 1996-11-05 | Affymax Technologies N.V. | Computer-aided engineering system for design of sequence arrays and lithographic masks |
AU707391B2 (en) | 1994-05-28 | 1999-07-08 | Tepnel Medical Limited | Producing copies of nucleic acids |
US5942391A (en) | 1994-06-22 | 1999-08-24 | Mount Sinai School Of Medicine | Nucleic acid amplification method: ramification-extension amplification method (RAM) |
JP3102800B2 (en) | 1994-08-19 | 2000-10-23 | パーキン−エルマー コーポレイション | Conjugation methods for amplification and ligation |
US5599668A (en) | 1994-09-22 | 1997-02-04 | Abbott Laboratories | Light scattering optical waveguide method for detecting specific binding events |
US5554744A (en) | 1994-09-23 | 1996-09-10 | Hybridon, Inc. | Method for loading solid supports for nucleic acid synthesis |
US5556752A (en) | 1994-10-24 | 1996-09-17 | Affymetrix, Inc. | Surface-bound, unimolecular, double-stranded DNA |
DE69535240T2 (en) | 1994-10-28 | 2007-06-06 | Gen-Probe Inc., San Diego | Compositions and methods for the simultaneous detection and quantification of a majority of specific nucleic acid sequences |
US5935825A (en) | 1994-11-18 | 1999-08-10 | Shimadzu Corporation | Process and reagent for amplifying nucleic acid sequences |
US5599695A (en) | 1995-02-27 | 1997-02-04 | Affymetrix, Inc. | Printing molecular library arrays using deprotection agents solely in the vapor phase |
US5624711A (en) | 1995-04-27 | 1997-04-29 | Affymax Technologies, N.V. | Derivatization of solid supports and methods for oligomer synthesis |
US5843650A (en) | 1995-05-01 | 1998-12-01 | Segev; David | Nucleic acid detection and amplification by chemical linkage of oligonucleotides |
US5545531A (en) | 1995-06-07 | 1996-08-13 | Affymax Technologies N.V. | Methods for making a device for concurrently processing multiple biological chip assays |
US5929227A (en) | 1995-07-12 | 1999-07-27 | The Regents Of The University Of California | Dimeric fluorescent energy transfer dyes comprising asymmetric cyanine azole-indolenine chromophores |
WO1998004689A1 (en) | 1995-07-31 | 1998-02-05 | Urocor, Inc. | Biomarkers and targets for diagnosis, prognosis and management of prostate disease |
US5916779A (en) | 1995-09-21 | 1999-06-29 | Becton, Dickinson And Company | Strand displacement amplification of RNA targets |
US5658734A (en) | 1995-10-17 | 1997-08-19 | International Business Machines Corporation | Process for synthesizing chemical compounds |
US5866331A (en) | 1995-10-20 | 1999-02-02 | University Of Massachusetts | Single molecule detection by in situ hybridization |
US5612473A (en) | 1996-01-16 | 1997-03-18 | Gull Laboratories | Methods, kits and solutions for preparing sample material for nucleic acid amplification |
US5928906A (en) | 1996-05-09 | 1999-07-27 | Sequenom, Inc. | Process for direct sequencing during template amplification |
US5939291A (en) | 1996-06-14 | 1999-08-17 | Sarnoff Corporation | Microfluidic method for nucleic acid amplification |
US5912124A (en) | 1996-06-14 | 1999-06-15 | Sarnoff Corporation | Padlock probe detection |
US5853990A (en) | 1996-07-26 | 1998-12-29 | Edward E. Winger | Real time homogeneous nucleotide assay |
US5849546A (en) | 1996-09-13 | 1998-12-15 | Epicentre Technologies Corporation | Methods for using mutant RNA polymerases with reduced discrimination between non-canonical and canonical nucleoside triphosphates |
US5853992A (en) | 1996-10-04 | 1998-12-29 | The Regents Of The University Of California | Cyanine dyes with high-absorbance cross section as donor chromophores in energy transfer labels |
US5853993A (en) | 1996-10-21 | 1998-12-29 | Hewlett-Packard Company | Signal enhancement method and kit |
US5905024A (en) | 1996-12-17 | 1999-05-18 | University Of Chicago | Method for performing site-specific affinity fractionation for use in DNA sequencing |
US5846729A (en) | 1997-02-27 | 1998-12-08 | Lorne Park Research, Inc. | Assaying nucleotides in solution using a fluorescent intensity quenching effect |
US5849497A (en) | 1997-04-03 | 1998-12-15 | The Research Foundation Of State University Of New York | Specific inhibition of the polymerase chain reaction using a non-extendable oligonucleotide blocker |
US5846726A (en) | 1997-05-13 | 1998-12-08 | Becton, Dickinson And Company | Detection of nucleic acids by fluorescence quenching |
US5928869A (en) | 1997-05-30 | 1999-07-27 | Becton, Dickinson And Company | Detection of nucleic acids by fluorescence quenching |
US5866366A (en) | 1997-07-01 | 1999-02-02 | Smithkline Beecham Corporation | gidB |
US5916776A (en) | 1997-08-27 | 1999-06-29 | Sarnoff Corporation | Amplification method for a polynucleotide |
US5935791A (en) | 1997-09-23 | 1999-08-10 | Becton, Dickinson And Company | Detection of nucleic acids by fluorescence quenching |
US5932451A (en) | 1997-11-19 | 1999-08-03 | Incyte Pharmaceuticals, Inc. | Method for unbiased mRNA amplification |
US6004755A (en) | 1998-04-07 | 1999-12-21 | Incyte Pharmaceuticals, Inc. | Quantitative microarray hybridizaton assays |
EP2280285A1 (en) * | 2003-09-15 | 2011-02-02 | Oklahoma Medical Research Foundation | Method of using cytokine assays to diagnose, treat, and evaluate inflammatory and autoimmune diseases |
JP5675829B2 (en) * | 2009-10-15 | 2015-02-25 | クレッシェンド バイオサイエンス インコーポレイテッド | Biomarkers and methods for measuring and monitoring inflammatory disease activity |
US20110250206A1 (en) | 2010-02-11 | 2011-10-13 | Axtell Robert C | Markers for determination of patient responsiveness |
EP2539470B1 (en) * | 2010-02-24 | 2017-02-22 | The Board of Trustees of The Leland Stanford Junior University | Methods for autoimmune disease diagnosis, prognosis, and treatment |
SG11201602540XA (en) * | 2013-10-03 | 2016-04-28 | Oklahoma Med Res Found | Biomarkers for systemic lupus erythematosus disease activity, and intensity and flare |
-
2014
- 2014-10-02 SG SG11201602540XA patent/SG11201602540XA/en unknown
- 2014-10-02 MX MX2016004283A patent/MX2016004283A/en unknown
- 2014-10-02 WO PCT/US2014/058812 patent/WO2015051110A1/en active Application Filing
- 2014-10-02 US US14/504,978 patent/US20150098940A1/en not_active Abandoned
- 2014-10-02 BR BR112016007391A patent/BR112016007391A2/en not_active IP Right Cessation
- 2014-10-02 EP EP14851316.1A patent/EP3052193B1/en active Active
- 2014-10-02 AU AU2014329535A patent/AU2014329535B2/en active Active
- 2014-10-02 CA CA2925004A patent/CA2925004C/en active Active
-
2016
- 2016-03-22 IL IL244734A patent/IL244734A0/en unknown
- 2016-08-11 US US15/234,754 patent/US10393739B2/en active Active
-
2019
- 2019-07-15 US US16/512,271 patent/US11585810B2/en active Active
-
2022
- 2022-09-16 US US17/946,756 patent/US20230266315A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
EP3052193A4 (en) | 2017-03-08 |
CA2925004C (en) | 2019-04-30 |
US20200049705A1 (en) | 2020-02-13 |
AU2014329535B2 (en) | 2017-09-07 |
US20230266315A1 (en) | 2023-08-24 |
CA2925004A1 (en) | 2015-04-09 |
US20160349256A1 (en) | 2016-12-01 |
US11585810B2 (en) | 2023-02-21 |
IL244734A0 (en) | 2016-04-21 |
US20150098940A1 (en) | 2015-04-09 |
US10393739B2 (en) | 2019-08-27 |
BR112016007391A2 (en) | 2017-08-01 |
EP3052193A1 (en) | 2016-08-10 |
MX2016004283A (en) | 2016-10-12 |
EP3052193B1 (en) | 2018-01-31 |
WO2015051110A1 (en) | 2015-04-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL244734A0 (en) | Biomarkers for systemic lupus erythematosus disease activity, and intensity and flare | |
HRP20181566T1 (en) | Cancer biomarkers and uses thereof | |
HK1218329A1 (en) | Type diabetes biomarkers and uses thereof | |
EP3015865A4 (en) | Biomarkers for cognitive dysfunction diseases and method for detecting cognitive dysfunction disease using biomarkers | |
EP3000205A4 (en) | Automatic data ring discovery and configuration | |
GB201301702D0 (en) | Exhaust cone | |
EP3155439A4 (en) | Biomarkers and methods for measuring and monitoring axial spondyloarthritis disease activity | |
GB201309426D0 (en) | Biomarkers | |
DK3016978T3 (en) | Humane anti-ifn-alpha-antistoffer | |
GB2513933B (en) | Wireless computer peripheral attachment device | |
IL244632A0 (en) | Cancer biomarker and diagnostic | |
GB201316526D0 (en) | Biomarkers | |
GB201308077D0 (en) | Biomarkers | |
EP3574114A4 (en) | Biomarkers for systemic lupus erythematosus disease activity, and intensity and flare | |
IL240618A0 (en) | Shell with ejectable shell base | |
GB201315974D0 (en) | Bearing shell | |
GB201316524D0 (en) | Biomarkers | |
GB201312638D0 (en) | Biomarkers | |
GB201322783D0 (en) | Biomarkers | |
GB201311827D0 (en) | Wireless Access Point | |
GB201316131D0 (en) | Biomarkers for disease stratification | |
GB201305061D0 (en) | Immunoassay for UR-144,XLR-11,metabolites and derivatives | |
EP3085782A4 (en) | 2-deoxy-scyllo-inosose reductase | |
GB201313342D0 (en) | Biomarkers | |
GB2518651B (en) | Wireless geometry discovery |