MX2015017089A - Tetrapeptidos derivados de quimioquinas c-x-c humanas utiles para tratar diversas afecciones en la piel. - Google Patents
Tetrapeptidos derivados de quimioquinas c-x-c humanas utiles para tratar diversas afecciones en la piel.Info
- Publication number
- MX2015017089A MX2015017089A MX2015017089A MX2015017089A MX2015017089A MX 2015017089 A MX2015017089 A MX 2015017089A MX 2015017089 A MX2015017089 A MX 2015017089A MX 2015017089 A MX2015017089 A MX 2015017089A MX 2015017089 A MX2015017089 A MX 2015017089A
- Authority
- MX
- Mexico
- Prior art keywords
- skin
- treatment
- psoriasis
- human
- various skin
- Prior art date
Links
- 108050006947 CXC Chemokine Proteins 0.000 title 1
- 102000019388 CXC chemokine Human genes 0.000 title 1
- 210000003491 skin Anatomy 0.000 abstract 5
- 201000004681 Psoriasis Diseases 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 230000000770 proinflammatory effect Effects 0.000 abstract 2
- 206010000591 Acrochordon Diseases 0.000 abstract 1
- 206010012438 Dermatitis atopic Diseases 0.000 abstract 1
- 241001303601 Rosacea Species 0.000 abstract 1
- 206010040925 Skin striae Diseases 0.000 abstract 1
- 208000031439 Striae Distensae Diseases 0.000 abstract 1
- 206010052428 Wound Diseases 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 230000032683 aging Effects 0.000 abstract 1
- 230000033115 angiogenesis Effects 0.000 abstract 1
- 201000008937 atopic dermatitis Diseases 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 210000002421 cell wall Anatomy 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 230000003828 downregulation Effects 0.000 abstract 1
- 239000012636 effector Substances 0.000 abstract 1
- 210000002889 endothelial cell Anatomy 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 210000002510 keratinocyte Anatomy 0.000 abstract 1
- 230000005012 migration Effects 0.000 abstract 1
- 238000013508 migration Methods 0.000 abstract 1
- 230000037311 normal skin Effects 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 201000004700 rosacea Diseases 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 abstract 1
- 210000003606 umbilical vein Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
- A61Q7/02—Preparations for inhibiting or slowing hair growth
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Birds (AREA)
- Toxicology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Abstract
Tetrapéptidos que consisten en la secuencia (I o V)-X1-K-X2, donde X1 puede seleccionarse entre E, Q o K y X2 puede seleccionarse entre M, F, I, W o V, que presentan actividades biológicas diversas. Pueden ser útiles para estimular la migración de los queratinocitos, para neutralizar el efecto proinflamatorio propio de determinados componentes de la pared de las bacterias, tales como los ácidos lipoteicoicos de las bacterias Gram positivas S. aureus, o para inducir la angiogénesis en las células provenientes del endotelio de la vena umbilical humana en cultivo. Mediante el uso de un modelo de la psoriasis basado en un tejido SOR-300-FT, también se ha demostrado que un péptido representativo fue útil para combatir diversas afecciones relacionadas con la inflamación. Por otro lado, la actividad biológica se analizó en función del perfil de diversos genes, en el contexto de un tratamiento sobre sustitutos de piel EPIDERMTM. Los péptidos de acuerdo con la presente invención, que presentan actividades biológicas diversas, pueden resultar útiles para tratar una variedad de afecciones en la piel, entre las que pueden mencionarse a modo de ejemplos no limitativos las heridas agudas o crónicas, las estrías, los efectos del envejecimiento, el deterioro del cabello y las afecciones relacionadas con la inflamación, tales como la psoriasis o la dermatitis atópica o la rosácea, así como para remover el cabello indeseable o las marcas en la piel.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361835424P | 2013-06-14 | 2013-06-14 | |
| PCT/US2014/037978 WO2014200651A1 (en) | 2013-06-14 | 2014-05-14 | Tetrapeptides derived from human c-x-c chemokines useful for treatment of various skin conditions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015017089A true MX2015017089A (es) | 2016-04-11 |
| MX362846B MX362846B (es) | 2019-02-19 |
Family
ID=50943603
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015017089A MX362846B (es) | 2013-06-14 | 2014-05-14 | Tetrapeptidos derivados de quimioquinas c-x-c humanas utiles para tratar diversas afecciones en la piel. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US10195245B2 (es) |
| EP (1) | EP3007716B1 (es) |
| JP (1) | JP6416240B2 (es) |
| KR (1) | KR102254260B1 (es) |
| CN (1) | CN105324122B (es) |
| AR (1) | AR096594A1 (es) |
| AU (1) | AU2014278708B2 (es) |
| BR (1) | BR112015031018B1 (es) |
| CA (1) | CA2915174C (es) |
| CY (1) | CY1119191T1 (es) |
| DK (1) | DK3007716T3 (es) |
| ES (1) | ES2631804T3 (es) |
| HK (1) | HK1217436A1 (es) |
| HU (1) | HUE032970T2 (es) |
| MX (1) | MX362846B (es) |
| MY (1) | MY168981A (es) |
| PL (1) | PL3007716T3 (es) |
| RU (1) | RU2687151C2 (es) |
| SG (1) | SG11201509048VA (es) |
| SI (1) | SI3007716T1 (es) |
| TW (1) | TWI511737B (es) |
| WO (1) | WO2014200651A1 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110302088A (zh) * | 2019-04-29 | 2019-10-08 | 杭州肽佳生物科技有限公司 | 一种包含修饰芋螺肽的化妆品组合物 |
| KR20220130144A (ko) * | 2020-01-21 | 2022-09-26 | 에이에스씨 리제니티 리미티드 | 피부의 외관 및 재생을 개선시키는 신규한 펩티드를 포함하는 국소 투여용 화장 제형 |
| PL245202B1 (pl) | 2020-03-06 | 2024-06-03 | Gdanski Univ Medyczny | Lipopeptydowe koniugaty i ich sole, sposób wytwarzania lipopeptydowych koniugatów i ich soli, kompozycja farmaceutyczna zawierająca lipopeptydowy koniugat i jego sole do leczenia ran przewlekłych |
| WO2022098051A1 (ko) | 2020-11-05 | 2022-05-12 | 한국생명공학연구원 | 항염 및 조직 재생작용을 갖는 신규 펩타이드 |
| CN113698452B (zh) * | 2021-08-23 | 2023-08-18 | 四川丽妍工坊生物科技有限公司 | 一种促皮肤修复肽、制备方法及其应用 |
| CA3233983A1 (en) * | 2021-11-02 | 2023-05-11 | Ole-Jan Iversen (Deceased) | Tri-, tetra and pentapeptides, compositions thereof and their use in the therapy of psoriasis |
| WO2023214802A1 (ko) * | 2022-05-03 | 2023-11-09 | 한국생명공학연구원 | 신규 펩타이드 및 이의 항염 및 재생 용도 |
| KR20240086709A (ko) * | 2022-11-18 | 2024-06-19 | (주)케어젠 | 피부 상태 개선 활성을 갖는 펩타이드 및 이의 용도 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991013904A1 (en) * | 1990-03-05 | 1991-09-19 | Cephalon, Inc. | Chymotrypsin-like proteases and their inhibitors |
| FR2814076B1 (fr) | 2000-09-21 | 2002-12-20 | Centre Nat Rech Scient | Agent angiogenique et ses utilisations |
| ZA200802546B (en) | 2005-08-29 | 2009-10-28 | Healor Ltd | Methods and compositions for prvention and treatment of diabetic and aged skin |
| PL3002294T3 (pl) | 2006-06-13 | 2018-08-31 | Helix Biomedix, Inc. | Fragmenty peptydowe do indukowania syntezy białek macierzy zewnątrzkomórkowej |
| JP2007001981A (ja) | 2006-07-10 | 2007-01-11 | Nippon Meat Packers Inc | 皮膚組織の再生及び肌質改善効果のあるペプチドを含有する化粧品 |
| CN101679495B (zh) | 2007-01-05 | 2013-07-17 | 赫里克斯生物医疗公司 | 用于细胞学和免疫学调节的短的生物活性肽 |
| KR101668803B1 (ko) | 2007-10-29 | 2016-10-24 | 헬릭스 바이오메딕스, 인코포레이티드 | 보호용 피부 관리 테트라펩티드 |
| EP2109054A1 (en) * | 2008-04-09 | 2009-10-14 | Biotempt B.V. | Methods for identifying biologically active peptides and predicting their function |
| TWI429451B (zh) | 2011-10-26 | 2014-03-11 | Nat Univ Tsing Hua | 對具有ｅｌｒ－ｃｘｃ趨化素高度親和力的受體蛋白細胞所引發疾病之拮抗治療劑 |
-
2014
- 2014-05-14 DK DK14730697.1T patent/DK3007716T3/en active
- 2014-05-14 SG SG11201509048VA patent/SG11201509048VA/en unknown
- 2014-05-14 CN CN201480033362.9A patent/CN105324122B/zh active Active
- 2014-05-14 US US14/907,811 patent/US10195245B2/en active Active
- 2014-05-14 JP JP2016519511A patent/JP6416240B2/ja active Active
- 2014-05-14 KR KR1020157037042A patent/KR102254260B1/ko active IP Right Grant
- 2014-05-14 RU RU2015146679A patent/RU2687151C2/ru active
- 2014-05-14 EP EP14730697.1A patent/EP3007716B1/en active Active
- 2014-05-14 CA CA2915174A patent/CA2915174C/en active Active
- 2014-05-14 HU HUE14730697A patent/HUE032970T2/en unknown
- 2014-05-14 AU AU2014278708A patent/AU2014278708B2/en active Active
- 2014-05-14 MY MYPI2015704511A patent/MY168981A/en unknown
- 2014-05-14 PL PL14730697T patent/PL3007716T3/pl unknown
- 2014-05-14 MX MX2015017089A patent/MX362846B/es active IP Right Grant
- 2014-05-14 BR BR112015031018-4A patent/BR112015031018B1/pt active IP Right Grant
- 2014-05-14 ES ES14730697.1T patent/ES2631804T3/es active Active
- 2014-05-14 SI SI201430262T patent/SI3007716T1/sl unknown
- 2014-05-14 WO PCT/US2014/037978 patent/WO2014200651A1/en active Application Filing
- 2014-06-12 TW TW103120387A patent/TWI511737B/zh active
- 2014-06-12 AR ARP140102248A patent/AR096594A1/es not_active Application Discontinuation
-
2016
- 2016-05-12 HK HK16105420.1A patent/HK1217436A1/zh unknown
-
2017
- 2017-06-22 CY CY20171100663T patent/CY1119191T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2015017089A (es) | Tetrapeptidos derivados de quimioquinas c-x-c humanas utiles para tratar diversas afecciones en la piel. | |
| CL2015002725A1 (es) | Compuestos aromáticos sustituidos para el tratamiento de la fibrosis pulmonar, la fibrosis hepática, la fibrosis de la piel y la fibrosis cardíaca | |
| BR112015024605A2 (pt) | sistemas e métodos para a produção visada de proteína terapêutica dentro de célula alvo | |
| BR112017012474A2 (pt) | composto peptídico, composição cosmética ou dermofarmacêutica, uso de pelo menos um composto peptídico, e, método para aumentar a atividade na síntese de macromoléculas do ecm da pele de um composto peptídico. | |
| EP3943092A3 (en) | Compositions for use in inducing differentiation of human brown adipocyte progenitors | |
| CO7010783A2 (es) | Proteína naglu humana recombinante y usos de la misma | |
| WO2016037071A3 (en) | Methods for treating aging and skin disorders using nucleic acids targeting tyr or mmp1 | |
| PE20142432A1 (es) | Usos terapeuticos de proteinas del factor de crecimiento del fibroblasto 21 | |
| BR112014008700A2 (pt) | composições úteis no tratamento de nefropatia e processos para preparação das mesmas | |
| MX2018009524A (es) | Composiciones del polipeptido de fusion tnfr: fc exentas de arginina y metodos de uso. | |
| BR112013026976A2 (pt) | alfa glucosidade ácida modificada com processamento acelerado | |
| UY33670A (es) | Anticuerpos de oncostatina m humana y metodos de uso | |
| BR112015015864A2 (pt) | composição farmacêutica, método de preparação de uma composição farmacêutica, método de tratamento de um indivíduo com uma condição de dor severa, e, uso de uma composição farmacêutica | |
| EA201290360A1 (ru) | Гуманизированные антитела против il-22ra человека | |
| TN2016000006A1 (en) | Benzyl-1h-pyrazolo[3,4-b]pyridines and use thereof | |
| MX2016005824A (es) | Metodo de cultivo celular. | |
| HRP20210031T1 (hr) | Pripravci i metode mutantskog faktora viii | |
| PH12017501070A1 (en) | Peptides and their use in the treatment of skin | |
| EA201490995A1 (ru) | Использование фо-ти для усиления мобилизации и пролиферации стволовых клеток | |
| BR112016009178A8 (pt) | método de preparação de um produto de tecido, e, uso de um produto de tecido | |
| MX367473B (es) | Composiciones de fosfato de calcio sustituido con magnesio amorfo, y sus usos. | |
| BR112016008786A2 (pt) | siRNA E SEUS USOS EM MÉTODOS E COMPOSIÇÕES PARA INIBIÇÃO DE EXPRESSÃO DO GENE ORAI1 | |
| GB201110777D0 (en) | Methods and uses | |
| WO2015040497A3 (en) | Methods for nuclear reprogramming of cells | |
| IN2014DN05784A (es) |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |