MX2015011965A - Metodos de creacion de bancos de celulas de alta densidad. - Google Patents
Metodos de creacion de bancos de celulas de alta densidad.Info
- Publication number
- MX2015011965A MX2015011965A MX2015011965A MX2015011965A MX2015011965A MX 2015011965 A MX2015011965 A MX 2015011965A MX 2015011965 A MX2015011965 A MX 2015011965A MX 2015011965 A MX2015011965 A MX 2015011965A MX 2015011965 A MX2015011965 A MX 2015011965A
- Authority
- MX
- Mexico
- Prior art keywords
- density cell
- cell banking
- methods
- banking methods
- density
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
- C12M33/14—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus with filters, sieves or membranes
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0278—Physical preservation processes
- A01N1/0284—Temperature processes, i.e. using a designated change in temperature over time
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0236—Mechanical aspects
- A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/26—Constructional details, e.g. recesses, hinges flexible
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/16—Vibrating; Shaking; Tilting
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/10—Perfusion
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/16—Hollow fibers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M3/00—Tissue, human, animal or plant cell, or virus culture apparatus
- C12M3/06—Tissue, human, animal or plant cell, or virus culture apparatus with filtration, ultrafiltration, inverse osmosis or dialysis means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
- C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M45/00—Means for pre-treatment of biological substances
- C12M45/22—Means for packing or storing viable microorganisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Sustainable Development (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Clinical Laboratory Science (AREA)
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- Mechanical Engineering (AREA)
- Water Supply & Treatment (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
La presente invención proporciona un método para la creación de un banco de células crioconservadas de alta densidad utilizando técnicas de cultivo de perfusión y concentración no centrífuga de células. También se proporcionan métodos de producción que emplean este banco de células crioconservadas de alta densidad.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361793021P | 2013-03-15 | 2013-03-15 | |
PCT/US2014/027757 WO2014143691A1 (en) | 2013-03-15 | 2014-03-14 | High-density cell banking methods |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2015011965A true MX2015011965A (es) | 2016-03-17 |
MX369521B MX369521B (es) | 2019-11-11 |
Family
ID=50687645
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015011965A MX369521B (es) | 2013-03-15 | 2014-03-14 | Metodos de creacion de bancos de celulas de alta densidad. |
Country Status (20)
Country | Link |
---|---|
US (2) | US10188099B2 (es) |
EP (2) | EP4008768A1 (es) |
JP (1) | JP6742902B2 (es) |
KR (2) | KR20210095233A (es) |
CN (2) | CN112410279A (es) |
AR (1) | AR095354A1 (es) |
AU (1) | AU2014228275B2 (es) |
BR (1) | BR112015021189B1 (es) |
CA (1) | CA2906600A1 (es) |
CY (1) | CY1125278T1 (es) |
DK (1) | DK2970843T3 (es) |
ES (1) | ES2894633T3 (es) |
HK (1) | HK1213284A1 (es) |
HU (1) | HUE056073T2 (es) |
IL (2) | IL241339B (es) |
MX (1) | MX369521B (es) |
RU (1) | RU2668796C2 (es) |
SG (2) | SG10201707554WA (es) |
TW (1) | TWI656839B (es) |
WO (1) | WO2014143691A1 (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2717927T3 (es) | 2013-02-22 | 2019-06-26 | Genzyme Corp | Procedimientos de cultivo por perfusión de microportadores y usos de los mismos |
MX367025B (es) | 2013-02-22 | 2019-08-02 | Genzyme Corp | Metodos de cultivo por perfusion con microportadores y usos de los mismos. |
CA2906600A1 (en) | 2013-03-15 | 2014-09-18 | Genzyme Corporation | High-density cell banking methods |
TWI743024B (zh) | 2014-06-06 | 2021-10-21 | 美商健臻公司 | 灌注培養方法及其用途 |
TWI776235B (zh) | 2014-06-09 | 2022-09-01 | 美商健臻公司 | 種子罐培養法(seed train processes)及其用途 |
CA2958149C (en) | 2014-08-14 | 2023-09-26 | Merial, Inc. | Novel cryopreservation bags and method of use thereof for closed system, high capacity cell-banking |
US20160100570A1 (en) * | 2014-09-18 | 2016-04-14 | Genzyme Corporation | Ultra-high density cell banking methods |
BR112017013423B1 (pt) | 2014-12-22 | 2023-04-11 | Genzyme Corporation | Métodos para cultivo de célula de mamífero |
RU2672318C1 (ru) * | 2017-09-19 | 2018-11-13 | Общество с ограниченной ответственностью "Международный Биотехнологический Центр "Генериум" | Способ получения моноклональных антител терапевтического назначения с помощью непрерывного культивирования клеток сно |
TW202003832A (zh) * | 2018-05-04 | 2020-01-16 | 美商健臻公司 | 具有過濾系統的灌注式生物反應器 |
CN109825436A (zh) * | 2019-03-12 | 2019-05-31 | 华道(上海)生物医药有限公司 | 全封闭细胞培养*** |
EP3795672A1 (en) * | 2019-09-18 | 2021-03-24 | Sartorius Stedim Biotech GmbH | System and method for the generation of high cell density seed culture |
CN117642493A (zh) * | 2021-07-13 | 2024-03-01 | 诺和诺德股份有限公司 | 人类多能干细胞及其衍生产物的大规模建库方法 |
WO2023287707A1 (en) * | 2021-07-15 | 2023-01-19 | Just-Evotec Biologics, Inc. | Bidirectional tangential flow filtration (tff) perfusion system |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69608668T2 (de) | 1995-02-23 | 2001-02-01 | Quest Int | Peptide für gewebe- und zellkulturmedien |
AUPN442295A0 (en) | 1995-07-26 | 1995-08-17 | Commonwealth Scientific And Industrial Research Organisation | Regulated autocrine growth of mammalian cells |
US6475725B1 (en) | 1997-06-20 | 2002-11-05 | Baxter Aktiengesellschaft | Recombinant cell clones having increased stability and methods of making and using the same |
AT407255B (de) | 1997-06-20 | 2001-02-26 | Immuno Ag | Rekombinanter zellklon mit erhöhter stabilität in serum- und proteinfreiem medium und verfahren zur gewinnung des stabilen zellklons |
US6391257B1 (en) | 1998-08-19 | 2002-05-21 | Prestone Products Corporation | Antifreeze compositions comprising carboxylic acid and cyclohexenoic acid |
EP1103610A1 (en) | 1999-11-26 | 2001-05-30 | Introgene B.V. | Production of vaccines from immortalised mammalian cell lines |
US6544424B1 (en) | 1999-12-03 | 2003-04-08 | Refined Technology Company | Fluid filtration system |
US6544788B2 (en) | 2001-02-15 | 2003-04-08 | Vijay Singh | Disposable perfusion bioreactor for cell culture |
US20030054331A1 (en) * | 2001-09-14 | 2003-03-20 | Stemsource, Inc. | Preservation of non embryonic cells from non hematopoietic tissues |
CN1930281A (zh) * | 2004-03-05 | 2007-03-14 | 帝斯曼知识产权资产管理有限公司 | 用于通过连续灌注和交互切向流来培养细胞的方法 |
US20060166364A1 (en) * | 2004-12-22 | 2006-07-27 | Introgen, Inc. | Use of flexible bag containers for viral production |
KR20150032915A (ko) * | 2005-04-08 | 2015-03-30 | 아르고스 쎄라퓨틱스 인코포레이티드 | 수지상 세포 조성물 및 방법 |
US8119368B2 (en) * | 2006-07-14 | 2012-02-21 | Dsm Ip Assets B.V. | Process for the culturing of cells |
CN102482633A (zh) * | 2009-07-06 | 2012-05-30 | 弗·哈夫曼-拉罗切有限公司 | 真核细胞的培养方法 |
EP2525899A1 (en) * | 2010-01-22 | 2012-11-28 | Lonza Walkersville, Inc. | High yield method and apparatus for volume reduction and washing of therapeutic cells using tangential flow filtration |
US10575515B2 (en) | 2010-05-04 | 2020-03-03 | The General Hospital Corporation | Methods and compositions for preserving tissues and organs |
JP5923529B2 (ja) * | 2011-03-18 | 2016-05-24 | ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ | 細胞培養用可撓性バッグ |
WO2013006461A1 (en) * | 2011-07-01 | 2013-01-10 | Biogen Idec Ma Inc. | Cholesterol-based media supplementals for cell culture |
CA2906600A1 (en) | 2013-03-15 | 2014-09-18 | Genzyme Corporation | High-density cell banking methods |
US20160100570A1 (en) | 2014-09-18 | 2016-04-14 | Genzyme Corporation | Ultra-high density cell banking methods |
-
2014
- 2014-03-14 CA CA2906600A patent/CA2906600A1/en active Pending
- 2014-03-14 CN CN202011052490.1A patent/CN112410279A/zh active Pending
- 2014-03-14 CN CN201480015761.2A patent/CN105102605A/zh active Pending
- 2014-03-14 AR ARP140101058A patent/AR095354A1/es unknown
- 2014-03-14 JP JP2016502533A patent/JP6742902B2/ja active Active
- 2014-03-14 HU HUE14723186A patent/HUE056073T2/hu unknown
- 2014-03-14 MX MX2015011965A patent/MX369521B/es active IP Right Grant
- 2014-03-14 US US14/212,607 patent/US10188099B2/en active Active
- 2014-03-14 WO PCT/US2014/027757 patent/WO2014143691A1/en active Application Filing
- 2014-03-14 DK DK14723186.4T patent/DK2970843T3/da active
- 2014-03-14 TW TW103109317A patent/TWI656839B/zh active
- 2014-03-14 SG SG10201707554WA patent/SG10201707554WA/en unknown
- 2014-03-14 EP EP21194097.8A patent/EP4008768A1/en active Pending
- 2014-03-14 EP EP14723186.4A patent/EP2970843B1/en not_active Revoked
- 2014-03-14 RU RU2015143439A patent/RU2668796C2/ru active
- 2014-03-14 AU AU2014228275A patent/AU2014228275B2/en active Active
- 2014-03-14 KR KR1020217023366A patent/KR20210095233A/ko not_active Application Discontinuation
- 2014-03-14 KR KR1020157027627A patent/KR102282939B1/ko active IP Right Grant
- 2014-03-14 BR BR112015021189-5A patent/BR112015021189B1/pt active IP Right Grant
- 2014-03-14 ES ES14723186T patent/ES2894633T3/es active Active
- 2014-03-14 SG SG11201506344TA patent/SG11201506344TA/en unknown
-
2015
- 2015-09-08 IL IL241339A patent/IL241339B/en active IP Right Grant
-
2016
- 2016-02-01 HK HK16101116.9A patent/HK1213284A1/zh unknown
-
2018
- 2018-12-13 US US16/219,332 patent/US20190223433A1/en not_active Abandoned
-
2019
- 2019-06-18 IL IL267468A patent/IL267468A/en unknown
-
2021
- 2021-11-16 CY CY20211100991T patent/CY1125278T1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX369521B (es) | Metodos de creacion de bancos de celulas de alta densidad. | |
TR201904270T4 (tr) | Tanımlı koşullar altında insan pluripotent kök hücrelerinin hematoendotelyal farklılaşması için yöntemler ve materyaller. | |
GB2555728A (en) | Cancer cell enrichment system | |
MX2021007613A (es) | Metodos de establecimiento de bancos de celulas de densidad ultra-alta. | |
IL249828A0 (en) | Limbal stem cells of cultured mammals, methods of their creation and uses thereof | |
TR201900776T4 (tr) | Memeli hücre kültürlerinin hasadına ilişkin yöntem. | |
MX2016002582A (es) | Metodo para producir celulas progenitoras hepaticas adultas. | |
BR112014028881A2 (pt) | populações de células, banco de células, métodos de obtenção de uma população de células, métodos de identificação de um fator, métodos de seleção, métodos de fornecimento de terapia, populações de hepatócitos e método de obtenção de células | |
CL2015003599A1 (es) | Solucion que contiene theralosa y dextrano para transplantar celulas de mamiferos | |
MX2016014235A (es) | Biosintesis microbiana de ergotioneina. | |
MX2018014043A (es) | Composiciones de cultivo celular con antioxidantes y metodos para la produccion de polipeptidos. | |
EP3683321A3 (en) | Methods relating to circulating tumor cell clusters and the treatment of cancer | |
MX369522B (es) | Metodos de cultivo por perfusión con microportadores y usos de los mismos. | |
MX2020009670A (es) | Metodos de cultivo por perfusion y usos de los mismos. | |
SG10201806083RA (en) | Microcarrier perfusion culturing methods and uses thereof | |
BR112017017886A2 (pt) | gerando populações de células endoteliais arteriais | |
MX2021001981A (es) | Metodos para preparar un poloxamero para usar en medio de cultivo celular. | |
EP3181686A4 (en) | Culture medium and method for enriching and maintaining cancer stem cells (cscs) using said medium | |
EP3067416A4 (en) | Method for introducing exogenous mitochondria into mammalian cells | |
NZ765734A (en) | Ph adjustment to improve thaw recovery of cell banks | |
DK3063266T3 (da) | Fremgangsmåde til kultivering af celler i adhæsionskultur under anvendelse af en cellekultur bærer i kapselform, samt cellekultur bærer dertil | |
EA201690684A1 (ru) | Способ осветления выросшей клеточной массы неочищенной культуры клеток с высокой плотностью клеток | |
MX353243B (es) | Metodo para incrementar la secrecion de proteinas recombinantes. | |
UA101125U (ru) | Способ определения койевой кислоты | |
UA87147U (ru) | СПОСОБ ИЗВЛЕЧЕНИЯ ВЫСОКОДИСПЕРСНОГО ЗОЛОТА ИЗ ВОДНЫХ МИНЕРАЛЬНЫХ суспензий |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |