MX2014003212A - Microorganismos y metodos para producir alquenos. - Google Patents
Microorganismos y metodos para producir alquenos.Info
- Publication number
- MX2014003212A MX2014003212A MX2014003212A MX2014003212A MX2014003212A MX 2014003212 A MX2014003212 A MX 2014003212A MX 2014003212 A MX2014003212 A MX 2014003212A MX 2014003212 A MX2014003212 A MX 2014003212A MX 2014003212 A MX2014003212 A MX 2014003212A
- Authority
- MX
- Mexico
- Prior art keywords
- alkene
- microorganisms
- methods
- pathway
- produce
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
- C12P5/026—Unsaturated compounds, i.e. alkenes, alkynes or allenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1229—Phosphotransferases with a phosphate group as acceptor (2.7.4)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1235—Diphosphotransferases (2.7.6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/002—Preparation of hydrocarbons or halogenated hydrocarbons cyclic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y402/00—Carbon-oxygen lyases (4.2)
- C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/30—Fuel from waste, e.g. synthetic alcohol or diesel
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Se describen organismos microbianos que no ocurren de manera natural conteniendo una trayectoria de alqueno teniendo al menos un ácido nucleico exógeno que codifica una enzima de la trayectoria de alqueno expresada en una cantidad suficiente para convertir un alcohol a un alqueno. La descripción proporciona adicionalmente métodos para usar tales organismos microbianos para producir un alqueno, al cultivar un organismo microbiano que no ocurre de manera natural conteniendo una trayectoria de alqueno como se describe en la presente bajo condiciones y durante un periodo de tiempo suficiente para producir un alqueno.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161535893P | 2011-09-16 | 2011-09-16 | |
PCT/US2012/055469 WO2013040383A1 (en) | 2011-09-16 | 2012-09-14 | Microorganisms and methods for producing alkenes |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2014003212A true MX2014003212A (es) | 2015-03-19 |
Family
ID=47883778
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014003212A MX2014003212A (es) | 2011-09-16 | 2012-09-14 | Microorganismos y metodos para producir alquenos. |
Country Status (11)
Country | Link |
---|---|
US (2) | US9988648B2 (es) |
EP (1) | EP2756082A4 (es) |
KR (1) | KR20140070605A (es) |
CN (1) | CN103946383A (es) |
AU (1) | AU2012308369A1 (es) |
BR (1) | BR112014006244A2 (es) |
CA (1) | CA2848972A1 (es) |
CO (1) | CO7020865A2 (es) |
MX (1) | MX2014003212A (es) |
SG (2) | SG11201400638VA (es) |
WO (1) | WO2013040383A1 (es) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9422578B2 (en) | 2011-06-17 | 2016-08-23 | Invista North America S.A.R.L. | Methods for biosynthesizing 1,3 butadiene |
CN103842513B (zh) | 2011-06-17 | 2017-05-17 | 英威达技术有限责任公司 | 产生1,3‑丁二烯的方法 |
SG11201400638VA (en) | 2011-09-16 | 2014-04-28 | Genomatica Inc | Microorganisms and methods for producing alkenes |
AU2012324935B2 (en) * | 2011-10-19 | 2016-01-14 | Scientist Of Fortune S.A. | Process for the enzymatic production of butadiene from crotyl alcohol |
US9212358B2 (en) | 2012-06-15 | 2015-12-15 | Microvi Biotech, Inc. | Biocatalyst compositions and processes for their use |
EP2867365A1 (en) * | 2012-06-29 | 2015-05-06 | Scientist of Fortune S.A. | Process for producing a c2-c10 monoalkene employing a terpene synthase or a prenyl transferase |
EP2920314A1 (en) * | 2012-11-13 | 2015-09-23 | Global Bioenergies | Process for the enzymatic preparation of isoprene from isoprenol |
US9777295B2 (en) | 2012-11-28 | 2017-10-03 | Invista North America S.A.R.L. | Methods for biosynthesis of isobutene |
WO2014099927A1 (en) * | 2012-12-17 | 2014-06-26 | Braskem S/A Ap 09 | Modified microorganisms and methods of using same for producing isoprene, 2-methyl-1-butanol, 2-methyl-1,3-butanediol, and/or 2-methylbut-2-en-1-ol |
US10294496B2 (en) | 2013-07-19 | 2019-05-21 | Invista North America S.A.R.L. | Methods for biosynthesizing 1,3 butadiene |
US10273518B2 (en) * | 2013-07-29 | 2019-04-30 | Invista North America S.A.R.L. | Methods for biosynthesizing 3-oxopent-4-enoyl-CoA |
US9862973B2 (en) | 2013-08-05 | 2018-01-09 | Invista North America S.A.R.L. | Methods for biosynthesis of isoprene |
WO2015021059A1 (en) | 2013-08-05 | 2015-02-12 | INVISTA North America S.á r.l. | Methods for biosynthesis of isobutene |
EP3077501B1 (en) | 2013-12-03 | 2021-07-28 | Genomatica, Inc. | Microorganisms and methods for improving product yields on methanol using acetyl-coa synthesis |
CA3192376A1 (en) | 2013-12-27 | 2015-07-02 | Genomatica, Inc. | Methods and organisms with increased carbon flux efficiencies |
CN106661597A (zh) | 2014-06-16 | 2017-05-10 | 英威达技术有限责任公司 | 用于产生戊二酸和戊二酸甲酯的方法 |
DK3194604T3 (da) | 2014-09-18 | 2020-05-25 | Genomatica Inc | Ikke-naturlig mikrobielle organismer med forbedret energisk effektivitet |
EP3280808B1 (en) | 2015-04-09 | 2020-09-16 | Genomatica, Inc. | Genetically engineered e. coli and methods for improved crotyl alcohol production |
EP3303421A4 (en) | 2015-05-30 | 2019-03-27 | Genomatica, Inc. | VINYL ISOMERASEDEHYDRATASES, ALKENOLDEHYDRATASES, LINALOOLDEHYDRATASES AND CROTYL ALCOHOL DEHYDRATASES AND METHOD FOR THE PRODUCTION AND USE THEREOF |
JP2018519829A (ja) * | 2015-07-21 | 2018-07-26 | ガバニング カウンシル オブ ザ ユニバーシティ オブ トロント | 1,3−ブタンジオールの産生のための方法および微生物 |
US11441128B2 (en) | 2015-10-30 | 2022-09-13 | Genomatica, Inc. | Methanol dehydrogenase fusion proteins |
CN109996865B (zh) * | 2016-07-12 | 2023-02-03 | 布拉斯肯有限公司 | 通过烷醇的酶促脱水形成烯烃 |
WO2018206262A1 (en) | 2017-05-10 | 2018-11-15 | Global Bioenergies | Improved methods for producing isobutene from 3-methylcrotonic acid |
US11634733B2 (en) | 2017-06-30 | 2023-04-25 | Inv Nylon Chemicals Americas, Llc | Methods, materials, synthetic hosts and reagents for the biosynthesis of hydrocarbons and derivatives thereof |
WO2019006257A1 (en) | 2017-06-30 | 2019-01-03 | Invista North America .S.A.R.L. | METHODS, SYNTHETIC HOSTS AND REAGENTS FOR HYDROCARBON BIOSYNTHESIS |
US11505809B2 (en) | 2017-09-28 | 2022-11-22 | Inv Nylon Chemicals Americas Llc | Organisms and biosynthetic processes for hydrocarbon synthesis |
US20210079334A1 (en) | 2018-01-30 | 2021-03-18 | Genomatica, Inc. | Fermentation systems and methods with substantially uniform volumetric uptake rate of a reactive gaseous component |
US20220177895A1 (en) | 2018-06-26 | 2022-06-09 | Genomatica, Inc. | Engineered microorganisms with g3p -> 3pg enzyme and/or fructose-1,6-bisphosphatase including those having synthetic or enhanced methylotrophy |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5958745A (en) | 1996-03-13 | 1999-09-28 | Monsanto Company | Methods of optimizing substrate pools and biosynthesis of poly-β-hydroxybutyrate-co-poly-β-hydroxyvalerate in bacteria and plants |
AU3482200A (en) | 1999-02-02 | 2000-08-25 | Bernhard Palsson | Methods for identifying drug targets based on genomic sequence data |
JP4776146B2 (ja) | 2001-01-10 | 2011-09-21 | ザ・ペン・ステート・リサーチ・ファンデーション | 細胞代謝をモデル化する方法及びシステム |
US7127379B2 (en) | 2001-01-31 | 2006-10-24 | The Regents Of The University Of California | Method for the evolutionary design of biochemical reaction networks |
EP1381860A4 (en) | 2001-03-01 | 2008-10-15 | Univ California | MODELS AND METHOD FOR DETERMINING SYSTEMIC PROPERTIES OF REGULATED RESPONSE NETWORKS |
US20030224363A1 (en) | 2002-03-19 | 2003-12-04 | Park Sung M. | Compositions and methods for modeling bacillus subtilis metabolism |
CA2480216A1 (en) | 2002-03-29 | 2003-10-09 | Genomatica, Inc. | Human metabolic models and methods |
US7856317B2 (en) | 2002-06-14 | 2010-12-21 | Genomatica, Inc. | Systems and methods for constructing genomic-based phenotypic models |
AU2003256480B2 (en) | 2002-07-10 | 2008-03-06 | The Penn State Research Foundation | Method for determining gene knockout strategies |
CA2500761C (en) | 2002-10-15 | 2012-11-20 | Bernhard O. Palsson | Methods and systems to identify operational reaction pathways |
CA2622026C (en) | 2005-10-26 | 2018-06-05 | E.I. Du Pont De Nemours And Company | Fermentive production of four carbon alcohols |
MX2009003824A (es) * | 2006-10-13 | 2010-04-07 | Basf Plant Science Gmbh | Plantas con rendimiento aumentado. |
AU2008212799A1 (en) | 2007-02-09 | 2008-08-14 | The Regents Of The University Of California | Biofuel production by recombinant microorganisms |
US7947483B2 (en) | 2007-08-10 | 2011-05-24 | Genomatica, Inc. | Methods and organisms for the growth-coupled production of 1,4-butanediol |
KR20100118973A (ko) * | 2007-12-13 | 2010-11-08 | 다니스코 유에스 인크. | 이소프렌을 생성하기 위한 조성물 및 방법 |
CN101952448A (zh) | 2007-12-23 | 2011-01-19 | 格沃股份有限公司 | 高产率产生异丁醇的酵母生物 |
JP2011518564A (ja) | 2008-04-23 | 2011-06-30 | ダニスコ・ユーエス・インク | 改良された微生物によるイソプレン産出用のイソプレンシンターゼ変異体 |
EP2344629B1 (en) | 2008-09-15 | 2018-01-24 | Danisco US Inc. | Systems using cell culture for production of isoprene |
CN102317437B (zh) | 2008-12-12 | 2013-08-21 | 麦特波力克斯公司 | 用于制备聚(5-羟基戊酸)和5碳化合物的绿色工艺和组合物 |
TW201120213A (en) * | 2009-06-17 | 2011-06-16 | Danisco Us Inc | Polymerization of isoprene from renewable resources |
CN102575265B (zh) * | 2009-06-22 | 2016-03-30 | 焦耳无限科技公司 | 在工程化的微生物中的1-烯烃的生物合成 |
EP2467490A1 (en) | 2009-08-21 | 2012-06-27 | Mascoma Corporation | Production of propanols, alcohols, and polyols in consolidated bioprocessing organisms |
EP2336340A1 (en) | 2009-12-21 | 2011-06-22 | Philippe Marliere | Method for producing an alkene comprising the step of converting an alcohol by an enzymatic dehydration step |
SG11201400638VA (en) | 2011-09-16 | 2014-04-28 | Genomatica Inc | Microorganisms and methods for producing alkenes |
-
2012
- 2012-09-14 SG SG11201400638VA patent/SG11201400638VA/en unknown
- 2012-09-14 CN CN201280056425.3A patent/CN103946383A/zh active Pending
- 2012-09-14 MX MX2014003212A patent/MX2014003212A/es unknown
- 2012-09-14 WO PCT/US2012/055469 patent/WO2013040383A1/en active Application Filing
- 2012-09-14 US US13/619,284 patent/US9988648B2/en active Active
- 2012-09-14 CA CA2848972A patent/CA2848972A1/en not_active Abandoned
- 2012-09-14 EP EP12831648.6A patent/EP2756082A4/en not_active Withdrawn
- 2012-09-14 SG SG10201502101WA patent/SG10201502101WA/en unknown
- 2012-09-14 BR BR112014006244A patent/BR112014006244A2/pt not_active IP Right Cessation
- 2012-09-14 AU AU2012308369A patent/AU2012308369A1/en not_active Abandoned
- 2012-09-14 KR KR1020147010141A patent/KR20140070605A/ko not_active Application Discontinuation
-
2014
- 2014-04-15 CO CO14082149A patent/CO7020865A2/es unknown
-
2018
- 2018-05-04 US US15/971,977 patent/US11932893B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
BR112014006244A2 (pt) | 2017-04-11 |
EP2756082A4 (en) | 2015-10-28 |
US20130122563A1 (en) | 2013-05-16 |
EP2756082A1 (en) | 2014-07-23 |
CN103946383A (zh) | 2014-07-23 |
KR20140070605A (ko) | 2014-06-10 |
US20190085360A1 (en) | 2019-03-21 |
CA2848972A1 (en) | 2013-03-21 |
US9988648B2 (en) | 2018-06-05 |
AU2012308369A1 (en) | 2014-04-03 |
SG10201502101WA (en) | 2015-05-28 |
CO7020865A2 (es) | 2014-08-11 |
SG11201400638VA (en) | 2014-04-28 |
US11932893B2 (en) | 2024-03-19 |
NZ622451A (en) | 2016-05-27 |
WO2013040383A1 (en) | 2013-03-21 |
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