MX2014001375A - Composicion farmaceutica para el tratamiento y/o prevencion del cancer. - Google Patents

Composicion farmaceutica para el tratamiento y/o prevencion del cancer.

Info

Publication number
MX2014001375A
MX2014001375A MX2014001375A MX2014001375A MX2014001375A MX 2014001375 A MX2014001375 A MX 2014001375A MX 2014001375 A MX2014001375 A MX 2014001375A MX 2014001375 A MX2014001375 A MX 2014001375A MX 2014001375 A MX2014001375 A MX 2014001375A
Authority
MX
Mexico
Prior art keywords
cancer
prophylaxis
treatment
pharmaceutical composition
antibody
Prior art date
Application number
MX2014001375A
Other languages
English (en)
Other versions
MX351682B (es
Inventor
Fumiyoshi Okano
Shinichi Kobayashi
Takanori Saito
Yoshitaka Minamida
Original Assignee
Toray Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries filed Critical Toray Industries
Publication of MX2014001375A publication Critical patent/MX2014001375A/es
Publication of MX351682B publication Critical patent/MX351682B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Hematology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La presente invención proporciona un anticuerpo que se dirige a una proteína antigénica cancerosa, específicamente expresada sobre la superficie de las células cancerosas, y el uso del mismo como un agente terapéutico y/o preventivo para el cáncer. Más específicamente, la presente invención proporciona un anticuerpo, o un fragmento del mismo que tiene reactividad inmunológica con un polipéptido CAPRIN-1 parcial que consiste de la secuencia de aminoácidos mostrada por la SEQ ID No.: 5 o una secuencia de aminoácidos que tiene 80 % o más de identidad secuencial a la secuencia de aminoácidos, y una composición farmacéutica para el tratamiento y/o prevención del cáncer, que comprende la misma, como un ingrediente activo.
MX2014001375A 2011-08-04 2012-08-03 Composicion farmaceutica para el tratamiento y/o prevencion del cancer. MX351682B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2011171300 2011-08-04
PCT/JP2012/069862 WO2013018894A1 (ja) 2011-08-04 2012-08-03 癌の治療及び／又は予防用医薬組成物

Publications (2)

Publication Number Publication Date
MX2014001375A true MX2014001375A (es) 2014-03-21
MX351682B MX351682B (es) 2017-10-25

Family

ID=47629408

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014001375A MX351682B (es) 2011-08-04 2012-08-03 Composicion farmaceutica para el tratamiento y/o prevencion del cancer.

Country Status (16)

Country Link
US (1) US9273128B2 (es)
EP (2) EP2740796B1 (es)
JP (1) JP6070191B2 (es)
KR (1) KR101979208B1 (es)
CN (1) CN103717740B (es)
AU (1) AU2012290957B2 (es)
BR (1) BR112014002608A2 (es)
CA (1) CA2844042C (es)
DK (2) DK2740796T3 (es)
ES (2) ES2634249T3 (es)
HU (2) HUE047006T2 (es)
MX (1) MX351682B (es)
PL (2) PL3351630T3 (es)
PT (2) PT2740796T (es)
RU (1) RU2641260C2 (es)
WO (1) WO2013018894A1 (es)

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DK3351630T3 (da) 2020-01-02
HUE047006T2 (hu) 2020-04-28
US9273128B2 (en) 2016-03-01
ES2763122T3 (es) 2020-05-27
JP6070191B2 (ja) 2017-02-01
KR101979208B1 (ko) 2019-05-16
AU2012290957B2 (en) 2017-04-20
EP2740796A4 (en) 2015-04-22
BR112014002608A2 (pt) 2018-02-20
RU2014108044A (ru) 2015-09-10
KR20140054185A (ko) 2014-05-08
RU2641260C2 (ru) 2018-01-16
US20140186359A1 (en) 2014-07-03
ES2634249T3 (es) 2017-09-27
EP2740796A1 (en) 2014-06-11
PL3351630T3 (pl) 2020-05-18
WO2013018894A1 (ja) 2013-02-07
CN103717740B (zh) 2015-10-21
DK2740796T3 (en) 2017-07-24
PT2740796T (pt) 2017-07-26
MX351682B (es) 2017-10-25
PT3351630T (pt) 2019-12-30
PL2740796T3 (pl) 2017-10-31
HUE033149T2 (en) 2017-11-28
JPWO2013018894A1 (ja) 2015-03-05
EP3351630B1 (en) 2019-10-16
EP3351630A1 (en) 2018-07-25
AU2012290957A1 (en) 2014-03-20
EP2740796B1 (en) 2017-05-17
CA2844042C (en) 2019-06-18
CA2844042A1 (en) 2013-02-07
CN103717740A (zh) 2014-04-09

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