MX2013014065A - Prueba diagnóstica molecular para el cancer. - Google Patents
Prueba diagnóstica molecular para el cancer.Info
- Publication number
- MX2013014065A MX2013014065A MX2013014065A MX2013014065A MX2013014065A MX 2013014065 A MX2013014065 A MX 2013014065A MX 2013014065 A MX2013014065 A MX 2013014065A MX 2013014065 A MX2013014065 A MX 2013014065A MX 2013014065 A MX2013014065 A MX 2013014065A
- Authority
- MX
- Mexico
- Prior art keywords
- cancer
- responsive
- angiogenesis
- present
- test
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57415—Specifically defined cancers of breast
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57449—Specifically defined cancers of ovaries
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/70—Mechanisms involved in disease identification
- G01N2800/7014—(Neo)vascularisation - Angiogenesis
Abstract
Se proporcionan métodos y composiciones para la identificación de una prueba diagnóstica molecular para el cáncer. La prueba identifica subtipos de cánceres que responden a terapéuticas anti-angiogénesis y permite la clasificación de un paciente dentro de este subtipo. La presente invención se puede usar para determinar si pacientes con cáncer responden o no responden de forma clínica a un régimen terapéutico previo a la administración de cualquier agente anti-angiogénico. Esta prueba se puede usar en diferentes tipos de cánceres y con diferentes fármacos que afectan directa o indirectamente la angiogénesis o la señalización angiogénesis. Además, la presente invención puede utilizarse como un indicador pronóstico para determinados tipos de cáncer. En particular, la presente invención se se dirige al uso de determinadas combinaciones de marcadores predictivos, donde la expresión de los marcadores predictivos se correlacionan con el grado de respuesta o de no respuesta a un régimen terapéutico.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161492488P | 2011-06-02 | 2011-06-02 | |
PCT/US2012/040805 WO2012167278A1 (en) | 2011-06-02 | 2012-06-04 | Molecular diagnostic test for cancer |
Publications (1)
Publication Number | Publication Date |
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MX2013014065A true MX2013014065A (es) | 2014-06-23 |
Family
ID=47259970
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2013014065A MX2013014065A (es) | 2011-06-02 | 2012-06-04 | Prueba diagnóstica molecular para el cancer. |
Country Status (13)
Country | Link |
---|---|
US (1) | US10260097B2 (es) |
EP (1) | EP2715348B1 (es) |
JP (2) | JP6067686B2 (es) |
KR (1) | KR20140044341A (es) |
CN (1) | CN103733065B (es) |
AU (1) | AU2012261820B2 (es) |
BR (1) | BR112013031019A2 (es) |
CA (1) | CA2838086A1 (es) |
EA (2) | EA025926B1 (es) |
IL (1) | IL229681A0 (es) |
MX (1) | MX2013014065A (es) |
SG (2) | SG195208A1 (es) |
WO (1) | WO2012167278A1 (es) |
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2012
- 2012-06-04 WO PCT/US2012/040805 patent/WO2012167278A1/en active Application Filing
- 2012-06-04 SG SG2013088216A patent/SG195208A1/en unknown
- 2012-06-04 JP JP2014513800A patent/JP6067686B2/ja not_active Expired - Fee Related
- 2012-06-04 AU AU2012261820A patent/AU2012261820B2/en not_active Ceased
- 2012-06-04 US US14/123,406 patent/US10260097B2/en not_active Expired - Fee Related
- 2012-06-04 EA EA201391805A patent/EA025926B1/ru not_active IP Right Cessation
- 2012-06-04 MX MX2013014065A patent/MX2013014065A/es unknown
- 2012-06-04 SG SG10201604497UA patent/SG10201604497UA/en unknown
- 2012-06-04 BR BR112013031019A patent/BR112013031019A2/pt not_active IP Right Cessation
- 2012-06-04 EP EP12793609.4A patent/EP2715348B1/en active Active
- 2012-06-04 CN CN201280037298.2A patent/CN103733065B/zh not_active Expired - Fee Related
- 2012-06-04 KR KR1020137034588A patent/KR20140044341A/ko not_active Application Discontinuation
- 2012-06-04 EA EA201691257A patent/EA201691257A1/ru unknown
- 2012-06-04 CA CA2838086A patent/CA2838086A1/en not_active Abandoned
-
2013
- 2013-11-28 IL IL229681A patent/IL229681A0/en unknown
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2016
- 2016-12-21 JP JP2016248061A patent/JP2017079772A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
US10260097B2 (en) | 2019-04-16 |
JP2014516552A (ja) | 2014-07-17 |
EA201391805A1 (ru) | 2014-03-31 |
CA2838086A1 (en) | 2012-12-06 |
IL229681A0 (en) | 2014-01-30 |
EA025926B1 (ru) | 2017-02-28 |
EA201691257A1 (ru) | 2017-02-28 |
US20140342924A1 (en) | 2014-11-20 |
CN103733065B (zh) | 2017-12-15 |
SG10201604497UA (en) | 2016-07-28 |
JP2017079772A (ja) | 2017-05-18 |
CN103733065A (zh) | 2014-04-16 |
SG195208A1 (en) | 2013-12-30 |
BR112013031019A2 (pt) | 2017-03-21 |
KR20140044341A (ko) | 2014-04-14 |
NZ618191A (en) | 2015-04-24 |
JP6067686B2 (ja) | 2017-01-25 |
EP2715348B1 (en) | 2019-04-10 |
EP2715348A4 (en) | 2015-10-07 |
EP2715348A1 (en) | 2014-04-09 |
AU2012261820B2 (en) | 2017-01-19 |
WO2012167278A1 (en) | 2012-12-06 |
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