BR112013031019A2 - teste diagnóstico molecular para câncer - Google Patents
teste diagnóstico molecular para câncerInfo
- Publication number
- BR112013031019A2 BR112013031019A2 BR112013031019A BR112013031019A BR112013031019A2 BR 112013031019 A2 BR112013031019 A2 BR 112013031019A2 BR 112013031019 A BR112013031019 A BR 112013031019A BR 112013031019 A BR112013031019 A BR 112013031019A BR 112013031019 A2 BR112013031019 A2 BR 112013031019A2
- Authority
- BR
- Brazil
- Prior art keywords
- cancer
- diagnostic test
- molecular diagnostic
- molecular
- test
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57415—Specifically defined cancers of breast
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57449—Specifically defined cancers of ovaries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/70—Mechanisms involved in disease identification
- G01N2800/7014—(Neo)vascularisation - Angiogenesis
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161492488P | 2011-06-02 | 2011-06-02 | |
| PCT/US2012/040805 WO2012167278A1 (en) | 2011-06-02 | 2012-06-04 | Molecular diagnostic test for cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112013031019A2 true BR112013031019A2 (pt) | 2017-03-21 |
Family
ID=47259970
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013031019A BR112013031019A2 (pt) | 2011-06-02 | 2012-06-04 | teste diagnóstico molecular para câncer |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US10260097B2 (pt) |
| EP (1) | EP2715348B1 (pt) |
| JP (2) | JP6067686B2 (pt) |
| KR (1) | KR20140044341A (pt) |
| CN (1) | CN103733065B (pt) |
| AU (1) | AU2012261820B2 (pt) |
| BR (1) | BR112013031019A2 (pt) |
| CA (1) | CA2838086A1 (pt) |
| EA (2) | EA025926B1 (pt) |
| IL (1) | IL229681A0 (pt) |
| MX (1) | MX2013014065A (pt) |
| SG (2) | SG195208A1 (pt) |
| WO (1) | WO2012167278A1 (pt) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012167278A1 (en) | 2011-06-02 | 2012-12-06 | Almac Diagnostics Limited | Molecular diagnostic test for cancer |
| EP2667193A1 (en) * | 2012-05-23 | 2013-11-27 | Université d'Aix-Marseille | MMP2 as a predictive biomarker of response to antiangiogenic therapy and survival after therapy in cancer patients |
| WO2014055398A1 (en) * | 2012-10-05 | 2014-04-10 | Siemens Healthcare Diagnostics Inc. | Method for detecting an increased risk or incidence of colorectal cancer |
| JP2015536667A (ja) | 2012-12-03 | 2015-12-24 | アルマック・ダイアグノスティクス・リミテッドＡｌｍａｃ Ｄｉａｇｎｏｓｔｉｃｓ Ｌｉｍｉｔｅｄ | 癌のための分子診断検査 |
| GB201313342D0 (en) * | 2013-07-26 | 2013-09-11 | Cancer Rec Tech Ltd | Biomarkers |
| US10456470B2 (en) | 2013-08-30 | 2019-10-29 | Genentech, Inc. | Diagnostic methods and compositions for treatment of glioblastoma |
| US10617755B2 (en) | 2013-08-30 | 2020-04-14 | Genentech, Inc. | Combination therapy for the treatment of glioblastoma |
| GB201409479D0 (en) * | 2014-05-28 | 2014-07-09 | Almac Diagnostics Ltd | Molecular diagnostic test for cancer |
| GB201409478D0 (en) * | 2014-05-28 | 2014-07-09 | Almac Diagnostics Ltd | Pro-angiogenic signature |
| GB201409476D0 (en) * | 2014-05-28 | 2014-07-09 | Almac Diagnostics Ltd | Molecular subtype for use in prognosis |
| JP2017523776A (ja) | 2014-07-14 | 2017-08-24 | ジェネンテック， インコーポレイテッド | 膠芽腫の診断方法及びその治療用組成物 |
| WO2016133374A1 (ko) * | 2015-02-17 | 2016-08-25 | 싸이퍼롬, 인코퍼레이티드 | 자궁수축억제제 부작용 방지를 위한 개인별 단백질 손상 정보 기반의 자궁수축억제제 선택 방법 |
| CN105160208A (zh) * | 2015-05-29 | 2015-12-16 | 杭州奥视图像技术有限公司 | 用于疾病亚型问题的基于网络的聚类方法 |
| GB201511546D0 (en) | 2015-07-01 | 2015-08-12 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers |
| EP3919507A3 (en) | 2015-07-01 | 2022-01-12 | Immatics Biotechnologies GmbH | Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers |
| US10650325B2 (en) * | 2015-07-31 | 2020-05-12 | Microsoft Technology Licensing, Llc | Deterministic message distribution |
| CA2996426A1 (en) | 2015-10-05 | 2017-04-13 | Cedars-Sinai Medical Center | Method of classifying and diagnosing cancer |
| KR102652347B1 (ko) * | 2016-01-25 | 2024-03-27 | 사노피 | 혈장 바이오마커 수준의 측정에 의해 암을 앓고 있는 것으로 의심되는 환자의 아플리베르셉트로의 치료 결과를 예측하는 방법 |
| US20190127805A1 (en) * | 2016-03-15 | 2019-05-02 | Almac Diagnostics Limited | Gene signatures for cancer detection and treatment |
| US11415584B2 (en) | 2016-12-28 | 2022-08-16 | Japanese Foundation For Cancer Research | Biomarkers, test method, and test kit for predicting therapeutic effect of anti-VEGFR-2 antibody drug |
| CN107037210A (zh) * | 2017-04-05 | 2017-08-11 | 北京蛋白质组研究中心 | Thbs2蛋白检测物在制备肝细胞癌诊断试剂盒中的应用 |
| US20200200760A1 (en) * | 2017-05-16 | 2020-06-25 | Lankenau Institute Of Medical Research | Compositions comprising ligands to rhob protein and the uses thereof |
| EP3879535A1 (en) | 2017-06-13 | 2021-09-15 | BostonGene Corporation | Systems and methods for identifying cancer treatments from normalized biomarker scores |
| WO2018236852A1 (en) * | 2017-06-19 | 2018-12-27 | Jungla Inc. | INTERPRETATION OF GENETIC AND GENOMIC VARIANTS VIA A MUTATIONAL LEARNING SYSTEM IN EXPERIMENTAL DEPTH AND INTEGRATED COMPUTER SCIENCE |
| EP3461915A1 (en) | 2017-10-02 | 2019-04-03 | Koninklijke Philips N.V. | Assessment of jak-stat1/2 cellular signaling pathway activity using mathematical modelling of target gene expression |
| EP3502279A1 (en) | 2017-12-20 | 2019-06-26 | Koninklijke Philips N.V. | Assessment of mapk-ap 1 cellular signaling pathway activity using mathematical modelling of target gene expression |
| WO2019165366A1 (en) * | 2018-02-23 | 2019-08-29 | Beth Israel Deaconess Medical Center | Drug efficacy evaluations |
| SG11202009696WA (en) * | 2018-04-13 | 2020-10-29 | Freenome Holdings Inc | Machine learning implementation for multi-analyte assay of biological samples |
| TWI815137B (zh) | 2018-06-15 | 2023-09-11 | 漢達生技醫藥股份有限公司 | 尼洛替尼十二烷基硫酸鹽之結晶 |
| WO2020006080A2 (en) * | 2018-06-27 | 2020-01-02 | Qcdx Llc | Biological sample holder and handler |
| CN109585011A (zh) * | 2018-10-26 | 2019-04-05 | 朱海燕 | 胸痛患者的病症诊断方法及机器可读存储介质 |
| MX2021005646A (es) * | 2018-11-14 | 2021-08-11 | Beyondspring Pharmaceuticals Inc | Métodos de tratamiento de cáncer con agentes de unión a tubulina. |
| WO2021016402A1 (en) * | 2019-07-22 | 2021-01-28 | Mission Bio, Inc. | Using machine learning to optimize assays for single cell targeted dna sequencing |
| KR102289533B1 (ko) * | 2019-08-19 | 2021-08-17 | 주식회사 테라젠바이오 | 특정 약물의 타겟 유전자와 관련된 시그니처를 기초로 타겟 유전자와 관련된 유전자들을 판단하는 전자 장치, 방법 및 상기 방법을 실행하기 위한 컴퓨터 프로그램 |
| CN112489800A (zh) * | 2020-12-03 | 2021-03-12 | 安徽医科大学第一附属医院 | 一种***癌患者的预后评估***及其应用 |
| CN116312814A (zh) * | 2021-12-02 | 2023-06-23 | 复旦大学 | 一种肺腺癌分子分型模型的构建方法、设备、装置以及试剂盒 |
Family Cites Families (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5202231A (en) | 1987-04-01 | 1993-04-13 | Drmanac Radoje T | Method of sequencing of genomes by hybridization of oligonucleotide probes |
| US5525464A (en) | 1987-04-01 | 1996-06-11 | Hyseq, Inc. | Method of sequencing by hybridization of oligonucleotide probes |
| GB8810400D0 (en) | 1988-05-03 | 1988-06-08 | Southern E | Analysing polynucleotide sequences |
| US5800992A (en) | 1989-06-07 | 1998-09-01 | Fodor; Stephen P.A. | Method of detecting nucleic acids |
| US6040138A (en) | 1995-09-15 | 2000-03-21 | Affymetrix, Inc. | Expression monitoring by hybridization to high density oligonucleotide arrays |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| US5547839A (en) | 1989-06-07 | 1996-08-20 | Affymax Technologies N.V. | Sequencing of surface immobilized polymers utilizing microflourescence detection |
| EP0430881A3 (en) | 1989-11-29 | 1991-10-23 | Ciba-Geigy Ag | Photochromic compounds, process for their preparation and their use |
| US5288644A (en) | 1990-04-04 | 1994-02-22 | The Rockefeller University | Instrument and method for the sequencing of genome |
| US5324633A (en) | 1991-11-22 | 1994-06-28 | Affymax Technologies N.V. | Method and apparatus for measuring binding affinity |
| DE69322266T2 (de) | 1992-04-03 | 1999-06-02 | Perkin Elmer Corp | Proben zusammensetzung und verfahren |
| US5503980A (en) | 1992-11-06 | 1996-04-02 | Trustees Of Boston University | Positional sequencing by hybridization |
| US5858659A (en) | 1995-11-29 | 1999-01-12 | Affymetrix, Inc. | Polymorphism detection |
| US5470710A (en) | 1993-10-22 | 1995-11-28 | University Of Utah | Automated hybridization/imaging device for fluorescent multiplex DNA sequencing |
| GB9401833D0 (en) | 1994-02-01 | 1994-03-30 | Isis Innovation | Method for discovering ligands |
| US6946442B2 (en) | 1994-11-30 | 2005-09-20 | Asif Syed Ahmed | Method of hastening cervical ripening |
| GB9507238D0 (en) | 1995-04-07 | 1995-05-31 | Isis Innovation | Detecting dna sequence variations |
| US5661028A (en) | 1995-09-29 | 1997-08-26 | Lockheed Martin Energy Systems, Inc. | Large scale DNA microsequencing device |
| JP2002515738A (ja) | 1996-01-23 | 2002-05-28 | アフィメトリックス，インコーポレイティド | 核酸分析法 |
| US6680175B2 (en) | 1998-05-05 | 2004-01-20 | Adherex Technologies, Inc. | Methods for diagnosing and evaluating cancer |
| WO2004005883A2 (en) | 2002-07-02 | 2004-01-15 | The Johns Hopkins University | Secreted and cytoplasmic tumor endothelial markers |
| US6998234B2 (en) | 2000-11-03 | 2006-02-14 | Oncotech, Inc. | Methods for cancer prognosis and diagnosis relating to tumor vascular endothelial cells |
| AU2003234613A1 (en) | 2002-05-15 | 2003-12-02 | Seul, Kyung, Hwan | Method of modulating angiogenesis |
| ME00425B (me) * | 2003-05-30 | 2011-10-10 | Genentech Inc | Liječenje sa anti-vegf antitijelima |
| WO2004108896A2 (en) | 2003-06-03 | 2004-12-16 | The Board Of Trustees Of The University Of Arkansas | Gene expression profiling of uterine serous papillary carcinomas and ovarian serous papillary tumors |
| JP4682152B2 (ja) | 2003-12-31 | 2011-05-11 | ザ・ペン・ステート・リサーチ・ファンデーション | 卵巣がんの化学療法に対する抵抗性を予測および克服するための方法ならびに結腸がんの発生を予測するための方法 |
| US20080113874A1 (en) * | 2004-01-23 | 2008-05-15 | The Regents Of The University Of Colorado | Gefitinib sensitivity-related gene expression and products and methods related thereto |
| ES2550614T3 (es) | 2004-04-09 | 2015-11-11 | Genomic Health, Inc. | Marcadores de expresión génica para predecir la respuesta a la quimioterapia |
| BRPI0511088A (pt) * | 2004-05-14 | 2007-12-26 | Monica Nister | identificação e caracterização de um subconjunto de glioblastomas sensìveis ao tratamento com imatinib |
| BRPI0513589A (pt) * | 2004-07-23 | 2008-05-13 | Astrazeneca Ab | método para selecionar um mamìfero tendo ou suspeito de ter um tumor para tratamento com uma droga de receptor de erbb |
| CA2586201A1 (en) | 2004-11-03 | 2006-05-11 | Almac Diagnostics Limited | Transcriptome microarray technology and methods of using the same |
| US7862995B2 (en) | 2004-12-10 | 2011-01-04 | Targeted Molecular Diagnostics | Methods and materials for predicting responsiveness to treatment with dual tyrosine kinase inhibitor |
| CA2601157A1 (en) | 2005-03-16 | 2006-09-28 | Osi Pharmaceuticals, Inc. | Biological markers predictive of anti-cancer response to epidermal growth factor receptor kinase inhibitors |
| EP1937837A2 (en) * | 2005-07-29 | 2008-07-02 | Siemens Healthcare Diagnostics Inc. | Methods and kits for the prediction of therapeutic success, recurrence free and overall survival in cancer therapies |
| ES2374450T3 (es) | 2005-09-20 | 2012-02-16 | OSI Pharmaceuticals, LLC | Marcadores biológicos predictivos de respuesta anticancerígena para inhibidores de cinasa del receptor del factor de crecimiento 1 similar a insulina. |
| US8445198B2 (en) * | 2005-12-01 | 2013-05-21 | Medical Prognosis Institute | Methods, kits and devices for identifying biomarkers of treatment response and use thereof to predict treatment efficacy |
| US20070128636A1 (en) | 2005-12-05 | 2007-06-07 | Baker Joffre B | Predictors Of Patient Response To Treatment With EGFR Inhibitors |
| WO2007067476A2 (en) * | 2005-12-05 | 2007-06-14 | Merck & Co., Inc. | Methods for predicting treatment response based on the expression profiles of protein and transcription biomakers |
| US20070212721A1 (en) | 2006-01-27 | 2007-09-13 | Tripath Imaging, Inc. | Methods for identifying patients with an increased likelihood of having ovarian cancer and compositions therefor |
| US20090275633A1 (en) | 2006-04-13 | 2009-11-05 | Oncomethylome Sciences Sa | Novel Tumour Suppressor |
| US8768629B2 (en) * | 2009-02-11 | 2014-07-01 | Caris Mpi, Inc. | Molecular profiling of tumors |
| CA2662508A1 (en) | 2006-09-19 | 2008-07-10 | Novartis Ag | Biomarkers of target modulation, efficacy, diagnosis and/or prognosis for raf inhibitors |
| JP2010535529A (ja) * | 2007-08-13 | 2010-11-25 | アルマック ダイアグノスティックス リミテッド | マイクロアレイ製造用３’ベースシークエンシング手法 |
| US20090092603A1 (en) | 2007-09-25 | 2009-04-09 | Bamdad Cynthia C | Early diagnosis and treatment of drug resistance in muc1-positive cancer |
| NZ562237A (en) | 2007-10-05 | 2011-02-25 | Pacific Edge Biotechnology Ltd | Proliferation signature and prognosis for gastrointestinal cancer |
| RU2010123381A (ru) | 2007-11-09 | 2011-12-20 | Дженентек, Инк. (Us) | Способ и композиции для диагностического применения у раковых пациентов |
| WO2009076229A2 (en) | 2007-12-07 | 2009-06-18 | Oregon Health & Science University | Methods to determine if a subject will respond to a bcr-abl inhibitor |
| US8114593B2 (en) | 2008-03-12 | 2012-02-14 | University Of Medicine And Dentistry Of New Jersey | Cancer biomarker genes and gene products and methods for using the same |
| EP2297349A1 (en) * | 2008-06-04 | 2011-03-23 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Diffuse large b-cell lymphoma markers and uses therefor |
| US20110195064A1 (en) | 2008-06-06 | 2011-08-11 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Serv | Survival predictor for diffuse large b cell lymphoma |
| KR20110052627A (ko) | 2008-07-16 | 2011-05-18 | 다나-파버 캔서 인스티튜트 인크. | 전립선암과 관련된 시그너처 및 ｐｃ결정인자 및 그의 사용 방법 |
| JP5606438B2 (ja) | 2008-07-23 | 2014-10-15 | エフ．ホフマン−ラ ロシュ アーゲー | 抗血管新生療法を受容可能な被験体の同定 |
| PT2368118E (pt) | 2008-12-23 | 2014-01-13 | Merck Patent Gmbh | Biomarcadores para inibidores com atividade anti-angiogénica |
| WO2010088688A2 (en) * | 2009-02-02 | 2010-08-05 | Biotheranostics, Inc. | Diagnosis of in situ and invasive breast cancer |
| WO2010127322A1 (en) | 2009-05-01 | 2010-11-04 | Genomic Health Inc. | Gene expression profile algorithm and test for likelihood of recurrence of colorectal cancer and response to chemotherapy |
| US7615353B1 (en) * | 2009-07-06 | 2009-11-10 | Aveo Pharmaceuticals, Inc. | Tivozanib response prediction |
| US20110064732A1 (en) | 2009-09-17 | 2011-03-17 | Sanne Lysbet De Haas | Methods and compositions for diagnostic use in cancer patients |
| CA2811015A1 (en) | 2010-09-15 | 2012-03-22 | Almac Diagnostics Limited | Molecular diagnostic test for cancer |
| WO2012052757A1 (en) * | 2010-10-20 | 2012-04-26 | Astrazeneca Ab | Tumour phenotype patient selection method |
| US20150024952A1 (en) | 2010-12-28 | 2015-01-22 | Arlet Alarcon | Molecular profiling for cancer |
| WO2012167278A1 (en) | 2011-06-02 | 2012-12-06 | Almac Diagnostics Limited | Molecular diagnostic test for cancer |
| KR20140114415A (ko) | 2012-01-13 | 2014-09-26 | 제넨테크, 인크. | Vegf 길항제로의 치료를 위한 환자를 확인하기 위한 생물학적 마커 |
| EP2667193A1 (en) | 2012-05-23 | 2013-11-27 | Université d'Aix-Marseille | MMP2 as a predictive biomarker of response to antiangiogenic therapy and survival after therapy in cancer patients |
| JP2015536667A (ja) | 2012-12-03 | 2015-12-24 | アルマック・ダイアグノスティクス・リミテッドＡｌｍａｃ Ｄｉａｇｎｏｓｔｉｃｓ Ｌｉｍｉｔｅｄ | 癌のための分子診断検査 |
-
2012
- 2012-06-04 WO PCT/US2012/040805 patent/WO2012167278A1/en active Application Filing
- 2012-06-04 SG SG2013088216A patent/SG195208A1/en unknown
- 2012-06-04 JP JP2014513800A patent/JP6067686B2/ja not_active Expired - Fee Related
- 2012-06-04 AU AU2012261820A patent/AU2012261820B2/en not_active Ceased
- 2012-06-04 US US14/123,406 patent/US10260097B2/en not_active Expired - Fee Related
- 2012-06-04 EA EA201391805A patent/EA025926B1/ru not_active IP Right Cessation
- 2012-06-04 MX MX2013014065A patent/MX2013014065A/es unknown
- 2012-06-04 SG SG10201604497UA patent/SG10201604497UA/en unknown
- 2012-06-04 BR BR112013031019A patent/BR112013031019A2/pt not_active IP Right Cessation
- 2012-06-04 EP EP12793609.4A patent/EP2715348B1/en active Active
- 2012-06-04 CN CN201280037298.2A patent/CN103733065B/zh not_active Expired - Fee Related
- 2012-06-04 KR KR1020137034588A patent/KR20140044341A/ko not_active Application Discontinuation
- 2012-06-04 EA EA201691257A patent/EA201691257A1/ru unknown
- 2012-06-04 CA CA2838086A patent/CA2838086A1/en not_active Abandoned
-
2013
- 2013-11-28 IL IL229681A patent/IL229681A0/en unknown
-
2016
- 2016-12-21 JP JP2016248061A patent/JP2017079772A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| US10260097B2 (en) | 2019-04-16 |
| JP2014516552A (ja) | 2014-07-17 |
| EA201391805A1 (ru) | 2014-03-31 |
| CA2838086A1 (en) | 2012-12-06 |
| IL229681A0 (en) | 2014-01-30 |
| EA025926B1 (ru) | 2017-02-28 |
| EA201691257A1 (ru) | 2017-02-28 |
| US20140342924A1 (en) | 2014-11-20 |
| CN103733065B (zh) | 2017-12-15 |
| SG10201604497UA (en) | 2016-07-28 |
| JP2017079772A (ja) | 2017-05-18 |
| CN103733065A (zh) | 2014-04-16 |
| SG195208A1 (en) | 2013-12-30 |
| KR20140044341A (ko) | 2014-04-14 |
| NZ618191A (en) | 2015-04-24 |
| JP6067686B2 (ja) | 2017-01-25 |
| EP2715348B1 (en) | 2019-04-10 |
| EP2715348A4 (en) | 2015-10-07 |
| MX2013014065A (es) | 2014-06-23 |
| EP2715348A1 (en) | 2014-04-09 |
| AU2012261820B2 (en) | 2017-01-19 |
| WO2012167278A1 (en) | 2012-12-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112013031019A2 (pt) | teste diagnóstico molecular para câncer | |
| HK1214633A1 (zh) | 癌症的分子診斷測試 | |
| ZA201508689B (en) | Molecular diagnostic test for cancer | |
| IL244472A0 (en) | Molecular diagnostic test for lung cancer | |
| DK2776833T3 (da) | Cobinder-understøttet testfremgangsmåde | |
| BR112014013745A2 (pt) | teste de imunosseleção de multiplex | |
| BR112013016193A2 (pt) | métodos para testagem de paternidade pré-natal não invasivos | |
| BR112013020540A2 (pt) | métodos para preparação de conjugados | |
| BR112014031435A2 (pt) | teste randomizado dentro de execução transacional | |
| NO20100183A1 (no) | Anordning for strømningsprøve | |
| BR112013012489A2 (pt) | sistema de teste de uniformidade de pneumático | |
| IL244471A0 (en) | Molecular diagnostic test for esophageal cancer | |
| BR112015003931A2 (pt) | composição de teste para detecção de cãncer | |
| BR112013012063A2 (pt) | teste não destrutivo para compósitos flexíveis | |
| BR112013012751A2 (pt) | aparelho complexo | |
| BR112014003473A2 (pt) | aparelhos indicadores de condição fisiológica particularizada | |
| DE112011101867B8 (de) | Fahrzeugfunktionsprüfstand | |
| BR112013012241A2 (pt) | método diagnóstico de teste de pneu | |
| BRPI1008243A2 (pt) | teste para detecção de tumor adrenal | |
| BR112013011545A2 (pt) | método para medir posição de componente | |
| DE112012003417A5 (de) | Strommessgerät | |
| ES1074974Y (es) | Aparato para la realizacion de ensayos presiometricos | |
| FI9874U1 (fi) | Järjestelmä lääketieteellisiä testejä varten | |
| IT1402961B1 (it) | Apparato di misura | |
| ES1091230Y (es) | Dispositivo para obtener piezas |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2517 DE 02-04-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |