MX2012015102A - Agentes terapeuticos 976. - Google Patents
Agentes terapeuticos 976.Info
- Publication number
- MX2012015102A MX2012015102A MX2012015102A MX2012015102A MX2012015102A MX 2012015102 A MX2012015102 A MX 2012015102A MX 2012015102 A MX2012015102 A MX 2012015102A MX 2012015102 A MX2012015102 A MX 2012015102A MX 2012015102 A MX2012015102 A MX 2012015102A
- Authority
- MX
- Mexico
- Prior art keywords
- therapeutic agents
- azetidinyl
- compound
- melanin
- prophylaxis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Abstract
Se describen en la presente los compuestos de azetidinilo de la formula (I), según se describió en la presente las composiciones farmacéuticas que comprenden un compuesto de azetidinilo y. un método para el uso de un compuesto azetidinilo en el tratamiento e profilaxis de una enfermedad o condición relacionada son le hormona do concentración de melanina.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36158510P | 2010-07-06 | 2010-07-06 | |
PCT/GB2011/051256 WO2012004588A2 (en) | 2010-07-06 | 2011-07-04 | Therapeutic agents 976 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2012015102A true MX2012015102A (es) | 2013-05-01 |
Family
ID=44514822
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012015102A MX2012015102A (es) | 2010-07-06 | 2011-07-04 | Agentes terapeuticos 976. |
Country Status (26)
Country | Link |
---|---|
US (1) | US8546375B2 (es) |
EP (1) | EP2590969B1 (es) |
JP (1) | JP5827683B2 (es) |
KR (1) | KR20130041177A (es) |
CN (1) | CN103209979B (es) |
AR (1) | AR082113A1 (es) |
AU (1) | AU2011275547B2 (es) |
BR (1) | BR112013000296A2 (es) |
CA (1) | CA2802832A1 (es) |
CL (1) | CL2013000027A1 (es) |
CR (1) | CR20130005A (es) |
CU (1) | CU20130004A7 (es) |
DO (1) | DOP2013000004A (es) |
EA (1) | EA201291384A1 (es) |
EC (1) | ECSP13012369A (es) |
ES (1) | ES2527466T3 (es) |
GT (1) | GT201300006A (es) |
HK (1) | HK1182712A1 (es) |
MX (1) | MX2012015102A (es) |
NI (1) | NI201200196A (es) |
PE (1) | PE20130781A1 (es) |
SA (1) | SA111320581B1 (es) |
SG (1) | SG186275A1 (es) |
TW (1) | TW201206916A (es) |
UY (1) | UY33487A (es) |
WO (1) | WO2012004588A2 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UY34194A (es) | 2011-07-15 | 2013-02-28 | Astrazeneca Ab | ?(3-(4-(espiroheterocíclico)metil)fenoxi)azetidin-1-il)(5-(fenil)-1,3,4-oxadiazol-2-il)metanona en el tratamiento de la obesidad? |
CN104974106B (zh) * | 2014-04-04 | 2019-02-22 | 浙江普洛康裕制药有限公司 | 5-烷基-[1,3,4]-噁二唑-2-甲酸烷基酯的合成方法 |
CN108840812B (zh) * | 2018-06-29 | 2020-08-18 | 南京富润凯德生物医药有限公司 | 一种3-(二氟甲基)-3-羟基氮杂环丁烷中间体及其盐的制备方法 |
Family Cites Families (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4212867A (en) * | 1977-03-03 | 1980-07-15 | Philagro | 2-Cyano-5-substituted 1,3,4-oxadiazoles and fungicidal compositions containing them |
DE3039087A1 (de) | 1980-10-16 | 1982-05-19 | Hoechst Ag, 6000 Frankfurt | 1-(1,3-dioxolan-2-ylmethyl)-azole, ihre salze, verfahren zu ihrer herstellung und ihre verwendung |
CA1247547A (en) | 1983-06-22 | 1988-12-28 | Paul Hadvary | Leucine derivatives |
GB8531071D0 (en) | 1985-12-17 | 1986-01-29 | Boots Co Plc | Therapeutic compound |
GB2184122B (en) | 1985-12-17 | 1989-10-18 | Boots Co Plc | N,n-dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methyl butylamine hydrochloride monohydrate |
EP0619814A1 (en) | 1991-12-31 | 1994-10-19 | Fujisawa Pharmaceutical Co., Ltd. | Oxadiazole derivatives having acetylcholinesterase-inhibitory and muscarinic agonist activity |
MX9702380A (es) | 1995-08-02 | 1998-02-28 | Uriach & Cia Sa J | Nuevas carboxamidas con actividad antifungica. |
SE0202134D0 (sv) | 2002-07-08 | 2002-07-08 | Astrazeneca Ab | Therapeutic agents |
EP1553089B1 (en) | 2002-07-30 | 2009-09-30 | Banyu Pharmaceutical Co., Ltd. | Antagonist of melanin-concentrating hormone receptor comprising benzimidazole derivative as active ingredient |
EP1593667A4 (en) | 2003-02-12 | 2009-03-04 | Takeda Pharmaceutical | AMINE DERIVATIVE |
US20060293298A1 (en) | 2003-04-10 | 2006-12-28 | Bamford Mark J | Compounds |
GB0400193D0 (en) | 2004-01-07 | 2004-02-11 | Astrazeneca Ab | Therapeutic agents |
WO2005066132A1 (en) | 2004-01-07 | 2005-07-21 | Astrazeneca Ab | Therapeutic agents i |
US7241787B2 (en) | 2004-01-25 | 2007-07-10 | Sanofi-Aventis Deutschland Gmbh | Substituted N-cycloexylimidazolinones, process for their preparation and their use as medicaments |
TW200538098A (en) | 2004-03-22 | 2005-12-01 | Astrazeneca Ab | Therapeutic agents |
ATE432926T1 (de) | 2004-07-26 | 2009-06-15 | Lilly Co Eli | Oxazolderivate als histamin-h3-rezeptor- wirkstoffe, deren herstellung und therapeutische verwendung |
SI1805169T1 (sl) | 2004-10-18 | 2009-06-30 | Lilly Co Eli | Inhibitorji histamin h3 receptorja, njihova priprava in terapevtske uporabe |
MX2007007226A (es) | 2004-12-17 | 2007-08-21 | Lilly Co Eli | Antagonistas receptores novedosos de hormona concentradora de melanina (mch). |
AR051802A1 (es) | 2004-12-21 | 2007-02-07 | Astrazeneca Ab | Heterociclos antagonistas de mchr1 |
JP2006176443A (ja) | 2004-12-22 | 2006-07-06 | Shionogi & Co Ltd | メラニン凝集ホルモン受容体アンタゴニスト |
BRPI0610907A2 (pt) | 2005-05-31 | 2008-12-02 | Astrazeneca Ab | composto ou precursores hidrolisÁveis in vivo ou sal farmaceuticamente aceitÁvel do mesmo, mÉtodos de tratamento ou profilaxia de uma doenÇa ou condiÇço na qual a modulaÇço do receptor de mch1 É benÉfica e de tratamento ou profilaxia de doenÇas, composiÇço farmacÊutica, e, uso de um composto |
US7709516B2 (en) | 2005-06-17 | 2010-05-04 | Endorecherche, Inc. | Helix 12 directed non-steroidal antiandrogens |
DE602006018301D1 (de) * | 2005-06-22 | 2010-12-30 | Pfizer Prod Inc | Histamin-3-rezeptorantagonisten |
WO2007011284A1 (en) | 2005-07-15 | 2007-01-25 | Astrazeneca Ab | Therapeutic agents |
JP2009522354A (ja) | 2006-01-06 | 2009-06-11 | アストラゼネカ・アクチエボラーグ | 化合物 |
CA2659155A1 (en) | 2006-07-20 | 2008-01-24 | Amgen Inc. | Substituted azole aromatic heterocycles as inhibitors of 11.beta.-hsd-1 |
WO2008020799A1 (en) | 2006-08-18 | 2008-02-21 | Astrazeneca Ab | Thienopyrimidin-4-one and thienopyridazin-7-one derivatives as mch rl antagonists |
CN101541796B (zh) | 2006-12-05 | 2012-11-07 | 詹森药业有限公司 | 用于mch-1介导的疾病的取代的二氮杂-螺-吡啶酮衍生物 |
EP2089397B1 (en) * | 2006-12-14 | 2012-08-29 | Eli Lilly & Company | 5- [4- (azetidin-3-yl0xy) -phenyl]-2-phenyl-5h-thiaz0l0 [5,4-c]pyridin-4-0ne derivatives and their use as mch receptor antagonists |
EP2148931A2 (en) | 2007-04-17 | 2010-02-03 | Vertex Pharmaceuticals Incorporated | Drug discovery methods for aurora kinase inhibitors |
AU2008282156B2 (en) | 2007-07-31 | 2014-07-17 | Vertex Pharmaceuticals Incorporated | Process for preparing 5-fluoro-1H-pyrazolo [3, 4-b] pyridin-3-amine and derivatives thereof |
JP2010536818A (ja) | 2007-08-22 | 2010-12-02 | エフ.ホフマン−ラ ロシュ アーゲー | Nk3受容体アンタゴニストとしてのピロリジンアリール−エーテル |
BRPI0818581A2 (pt) * | 2007-10-17 | 2015-07-21 | Sanofi Aventis | Carboxamidas n-fenil-bipirrolidina substituídas e uso terapêutico das mesmas |
US8124636B2 (en) | 2008-04-30 | 2012-02-28 | Hoffmann-La Roche Inc. | Imidazolidinone derivatives as 11B-HSD1 inhibitors |
JP5780954B2 (ja) * | 2008-05-08 | 2015-09-16 | エヴォテック・アクチエンゲゼルシャフト | ヒスタミンh3受容体アンタゴニストとしてのアゼチジン類及びシクロブタン類 |
SA110310332B1 (ar) * | 2009-05-01 | 2013-12-10 | Astrazeneca Ab | مركبات ميثانون (3 استبدال -ازيتيدين -1-يل )(5- فينيل -1، 3، 4- أوكساديازول -2-يل ) |
WO2011019090A1 (en) | 2009-08-13 | 2011-02-17 | Mitsubishi Tanabe Pharma Corporation | Pyrimidone derivatives used as tau protein kinase 1 inhibitors |
US9051296B2 (en) * | 2009-11-16 | 2015-06-09 | Raqualia Pharma Inc. | Aryl carboxamide derivatives as TTX-S blockers |
-
2011
- 2011-07-04 CA CA2802832A patent/CA2802832A1/en not_active Abandoned
- 2011-07-04 BR BR112013000296A patent/BR112013000296A2/pt not_active IP Right Cessation
- 2011-07-04 WO PCT/GB2011/051256 patent/WO2012004588A2/en active Application Filing
- 2011-07-04 AU AU2011275547A patent/AU2011275547B2/en not_active Ceased
- 2011-07-04 ES ES11729458.7T patent/ES2527466T3/es active Active
- 2011-07-04 SG SG2012090882A patent/SG186275A1/en unknown
- 2011-07-04 SA SA111320581A patent/SA111320581B1/ar unknown
- 2011-07-04 EP EP11729458.7A patent/EP2590969B1/en active Active
- 2011-07-04 MX MX2012015102A patent/MX2012015102A/es active IP Right Grant
- 2011-07-04 EA EA201291384A patent/EA201291384A1/ru unknown
- 2011-07-04 PE PE2013000016A patent/PE20130781A1/es not_active Application Discontinuation
- 2011-07-04 KR KR1020137003150A patent/KR20130041177A/ko not_active Application Discontinuation
- 2011-07-04 CN CN201180042363.6A patent/CN103209979B/zh not_active Expired - Fee Related
- 2011-07-04 JP JP2013517542A patent/JP5827683B2/ja not_active Expired - Fee Related
- 2011-07-05 TW TW100123724A patent/TW201206916A/zh unknown
- 2011-07-05 US US13/176,554 patent/US8546375B2/en not_active Expired - Fee Related
- 2011-07-05 AR ARP110102401A patent/AR082113A1/es not_active Application Discontinuation
- 2011-07-06 UY UY0001033487A patent/UY33487A/es not_active Application Discontinuation
-
2012
- 2012-12-28 NI NI201200196A patent/NI201200196A/es unknown
-
2013
- 2013-01-03 CL CL2013000027A patent/CL2013000027A1/es unknown
- 2013-01-04 GT GT201300006A patent/GT201300006A/es unknown
- 2013-01-04 CU CU2013000004A patent/CU20130004A7/es unknown
- 2013-01-04 DO DO2013000004A patent/DOP2013000004A/es unknown
- 2013-01-04 EC ECSP13012369 patent/ECSP13012369A/es unknown
- 2013-01-07 CR CR20130005A patent/CR20130005A/es unknown
- 2013-08-30 HK HK13110163.5A patent/HK1182712A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CU20130004A7 (es) | 2013-05-31 |
CR20130005A (es) | 2013-04-17 |
NI201200196A (es) | 2013-10-16 |
CA2802832A1 (en) | 2012-01-12 |
WO2012004588A2 (en) | 2012-01-12 |
AU2011275547B2 (en) | 2015-10-29 |
ES2527466T3 (es) | 2015-01-26 |
AU2011275547A1 (en) | 2013-02-07 |
JP2013535413A (ja) | 2013-09-12 |
KR20130041177A (ko) | 2013-04-24 |
ECSP13012369A (es) | 2013-01-31 |
US8546375B2 (en) | 2013-10-01 |
PE20130781A1 (es) | 2013-07-20 |
TW201206916A (en) | 2012-02-16 |
BR112013000296A2 (pt) | 2019-09-24 |
CN103209979A (zh) | 2013-07-17 |
SA111320581B1 (ar) | 2014-06-17 |
US20120010189A1 (en) | 2012-01-12 |
DOP2013000004A (es) | 2013-04-30 |
EA201291384A1 (ru) | 2013-07-30 |
UY33487A (es) | 2012-02-29 |
AR082113A1 (es) | 2012-11-14 |
EP2590969A2 (en) | 2013-05-15 |
CN103209979B (zh) | 2016-02-10 |
GT201300006A (es) | 2014-11-06 |
HK1182712A1 (en) | 2013-12-06 |
CL2013000027A1 (es) | 2013-03-08 |
EP2590969B1 (en) | 2014-10-15 |
SG186275A1 (en) | 2013-01-30 |
JP5827683B2 (ja) | 2015-12-02 |
WO2012004588A3 (en) | 2012-08-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |