MX2008001554A - Composiciones que comprenden un donador de no y un ditiolane, y su uso para mejorar la funcion sexual. - Google Patents

Composiciones que comprenden un donador de no y un ditiolane, y su uso para mejorar la funcion sexual.

Info

Publication number
MX2008001554A
MX2008001554A MX2008001554A MX2008001554A MX2008001554A MX 2008001554 A MX2008001554 A MX 2008001554A MX 2008001554 A MX2008001554 A MX 2008001554A MX 2008001554 A MX2008001554 A MX 2008001554A MX 2008001554 A MX2008001554 A MX 2008001554A
Authority
MX
Mexico
Prior art keywords
donor
dithiolane
compositions
improvement
sexual function
Prior art date
Application number
MX2008001554A
Other languages
English (en)
Inventor
Klaus Wessel
Original Assignee
Extarma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Extarma Ag filed Critical Extarma Ag
Publication of MX2008001554A publication Critical patent/MX2008001554A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

La presente invencion se refiere a composiciones solidas que comprenden una sustancia que mejora la disponibilidad del oxido nitrico (NO), es decir, un donador de NO o un precursor de la biosintesis del NO o un agonista directo o indirecto, con arginina siendo un compuesto preferido, en combinacion con un ditiolane, con acido a-lipoico como un compuesto preferido, y su uso para mejorar la funcion sexual. Las composiciones de acuerdo con la invencion comprenden el donador de NO o su precursor en exceso, sobre la base de la cantidad molar de los constituyentes. Las composiciones son tambien adecuadas para el mejoramiento de la funcion sexual. En particular, la presente invencion se refiere al uso de un ditiolane en combinacion con un donador de NO o un precursor de este para la preparacion de un medicamento para el tratamiento de la disfuncion sexual.
MX2008001554A 2005-08-04 2006-08-04 Composiciones que comprenden un donador de no y un ditiolane, y su uso para mejorar la funcion sexual. MX2008001554A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05107206A EP1754478B1 (en) 2005-08-04 2005-08-04 Liquid Composition comprising arginine and alpha-lipoic acid and its use for improvement of sexual function
PCT/EP2006/007733 WO2007017191A2 (en) 2005-08-04 2006-08-04 Compositions comprising an no donor and a dithiolane and their use for improvement of sexual function

Publications (1)

Publication Number Publication Date
MX2008001554A true MX2008001554A (es) 2008-04-22

Family

ID=35502745

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2008001554A MX2008001554A (es) 2005-08-04 2006-08-04 Composiciones que comprenden un donador de no y un ditiolane, y su uso para mejorar la funcion sexual.

Country Status (17)

Country Link
US (1) US9107889B2 (es)
EP (2) EP1754478B1 (es)
JP (3) JP5295766B2 (es)
CN (2) CN102670591B (es)
AT (1) ATE418976T1 (es)
BR (1) BRPI0614434B8 (es)
CY (2) CY1109430T1 (es)
DE (1) DE602005012089D1 (es)
DK (2) DK1754478T3 (es)
ES (2) ES2320560T3 (es)
MX (1) MX2008001554A (es)
PL (2) PL1754478T3 (es)
PT (2) PT1754478E (es)
RU (1) RU2423120C2 (es)
SI (2) SI1754478T1 (es)
UA (1) UA95917C2 (es)
WO (1) WO2007017191A2 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1754478T3 (da) 2005-08-04 2009-05-04 Encrypta Gmbh Flydende sammensætning omfattende arginin og alfa-liponsyre og anvendelse heraf til forbedring af den seksuelle funktion
FR2939042B1 (fr) * 2008-11-28 2010-11-26 Oreal PROCEDE DE DEPIGMENTATION DES MATIERES KERATINIQUES A l'AIDE DE COMPOSES DITHIOLANNES.
RU2458537C1 (ru) * 2011-03-14 2012-08-20 Общество С Ограниченной Ответственностью "Парафарм" Биологически активная добавка к пище для профилактики эректильной дисфункции у мужчин
FR3012039A1 (fr) * 2013-10-22 2015-04-24 Philippe Olivier Gorny Medicament ou produit dietetique et son utilisation pour prevenir ou traiter les dysfonctionnements sexuels de l'homme et de la femme
DK180173B1 (en) 2018-12-07 2020-07-14 Inxo Ivs Compositions for improving sexual function
US11571405B2 (en) 2018-12-07 2023-02-07 Inxo A/S Compositions for improving sexual function
CN109876194B (zh) * 2019-04-11 2021-04-02 湖北大学 一种可调节降解速率的poss-peg杂化水凝胶及其制备方法和其应用

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3364822D1 (en) 1982-03-15 1986-09-04 Ici Plc Process of oxidising hydrocarbons
DE3629116A1 (de) * 1986-08-27 1988-03-10 Asta Pharma Ag Verfahren zur herstellung enantiomerenreiner r-(+)-(alpha)-liponsaeure und s-(-)-(alpha)-liponsaeure (thioctsaeure) sowie nonen- beziehungsweise mesylderivate als zwischenprodukte hierfuer
DE3840076A1 (de) 1987-12-04 1989-06-15 Asta Pharma Ag Injizierbare loesung des thioctsaeuresalzes mit trometamol und/oder basischen aminosaeuren
EP0318891B1 (de) 1987-12-04 1992-01-02 ASTA Medica Aktiengesellschaft Injizierbare Lösung des Thioctsäuresalzes mit Trometamol und/oder basischen Aminosäuren
JPH03169813A (ja) 1989-11-09 1991-07-23 Asta Pharma Ag 細胞保護作用を有する疼痛及び炎症性疾患及び／又はレトロウイルスに起因する病気の治療用医薬並びにその製法
DE4137773A1 (de) 1991-11-16 1993-05-19 Degussa Herstellung und verwendung von salzen der reinen enantiomere der (alpha)-liponsaeure
JP2684287B2 (ja) * 1991-12-20 1997-12-03 株式会社河合楽器製作所 楽器自動演奏装置
US5223285A (en) * 1992-03-31 1993-06-29 Abbott Laboratories Nutritional product for pulmonary patients
DE4317646A1 (de) 1993-05-27 1994-12-01 Asta Medica Ag Tabletten mit Thioctsäure und mindestens einer basischen Komponente
DE4433764A1 (de) 1994-09-22 1996-03-28 Asta Medica Ag Darreichungsformen enthaltend alpha-Liponsäure, feste Salze von R-Thioctsäure mit verbesserter Freisetzung und Bioverfügbarkeit
US6234176B1 (en) 1996-06-21 2001-05-22 Integrated Medical Systems, Inc. Data logger for transportable life support system
US7504376B2 (en) * 1996-08-12 2009-03-17 Natural Alternatives International Methods and compositions for increasing the anaerobic working capacity in tissues
US6387645B1 (en) * 1998-07-16 2002-05-14 Hyseq, Inc. Methods and materials relating to novel CD39-like polypeptides
US20020068365A1 (en) * 1998-07-28 2002-06-06 Eric H. Kuhrts Controlled release nitric oxide producing agents
US6207190B1 (en) * 1998-08-13 2001-03-27 Chronorx, Llc Dosage forms for the treatment of the chronic glaucomas
FR2791571B1 (fr) 1999-04-02 2002-10-04 Sod Conseils Rech Applic Association inhibiteur(s) de no synthase et antioxydant(s) metabolique(s)
AR042572A1 (es) 1999-04-02 2005-06-29 Sod Conseils Rech Applic Derivados de acido lipoico, procedimiento para su preparacion, medicamentos y composiciones farmaceuticas que los contienen y utilizacion de dichos derivados para la preparacion de los referidos medicamentos
ES2162586B1 (es) 1999-11-25 2002-07-01 Moraleda Manuel Gomez Composicion que comprende aceites ozonizados y/o otros productos naturales y/o sinteticos ozonizados, y su empleo en composiciones farmaceuticas, cosmeticas, dieteticas o de suplementos alimentarios, en los campos humano y veterinario
CA2399500A1 (en) * 2000-02-01 2001-08-09 Muscletech Research And Development Inc. Alpha lipoic acid based food supplement for increasing lean muscle mass and strength
US6387945B2 (en) 2000-04-11 2002-05-14 The Regents Of The University Of California Lipoic acid analogs
US6420342B1 (en) 2000-05-08 2002-07-16 N.V. Nutricia Nutritional preparation comprising ribose and medical use thereof
US7128930B1 (en) * 2000-09-01 2006-10-31 Meir S. Sacks Compositions and methods for treating sexual dysfunction
US6923960B2 (en) 2001-10-03 2005-08-02 Vsl Pharmaceuticals Inc. Antioxidant combination composition and use thereof
ITRM20010621A1 (it) 2001-10-18 2003-04-18 Aldo Fassi Sali metallici non igroscopici e idrosolubili di alcanoil l-carnitine, integratori dietetici che li contengono e kit dietetici, per contrast
AU2002254546A1 (en) * 2002-04-03 2003-10-20 Mitchell A. Avery Lipoic acid analogs useful as provitamins and antioxidants
NL1022153C2 (nl) * 2002-12-12 2004-06-15 Tno Cholesterol verlagend preparaat, voedingssupplement en voedingsmiddel en werkwijzen voor de bereiding daarvan.
DK1754478T3 (da) 2005-08-04 2009-05-04 Encrypta Gmbh Flydende sammensætning omfattende arginin og alfa-liponsyre og anvendelse heraf til forbedring af den seksuelle funktion

Also Published As

Publication number Publication date
DK1909782T3 (da) 2012-08-27
ES2320560T3 (es) 2009-05-25
BRPI0614434A2 (pt) 2011-03-29
CY1113235T1 (el) 2016-04-13
CY1109430T1 (el) 2014-08-13
PT1754478E (pt) 2009-03-31
ES2388074T3 (es) 2012-10-08
CN102670591A (zh) 2012-09-19
JP2009508810A (ja) 2009-03-05
SI1754478T1 (sl) 2009-06-30
JP2013136616A (ja) 2013-07-11
PL1754478T3 (pl) 2009-07-31
UA95917C2 (ru) 2011-09-26
PT1909782E (pt) 2012-08-16
DK1754478T3 (da) 2009-05-04
EP1909782A2 (en) 2008-04-16
RU2423120C2 (ru) 2011-07-10
ATE418976T1 (de) 2009-01-15
JP2016104738A (ja) 2016-06-09
EP1909782B1 (en) 2012-05-16
JP5295766B2 (ja) 2013-09-18
JP5925714B2 (ja) 2016-05-25
WO2007017191A3 (en) 2007-05-24
CN102670591B (zh) 2014-08-06
RU2008107877A (ru) 2009-09-10
PL1909782T3 (pl) 2012-12-31
SI1909782T1 (sl) 2012-09-28
US20080161381A1 (en) 2008-07-03
WO2007017191A2 (en) 2007-02-15
CN101237862B (zh) 2012-03-21
CN101237862A (zh) 2008-08-06
BRPI0614434B1 (pt) 2020-04-28
DE602005012089D1 (de) 2009-02-12
EP1754478A1 (en) 2007-02-21
BRPI0614434B8 (pt) 2021-05-25
US9107889B2 (en) 2015-08-18
EP1754478B1 (en) 2008-12-31

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Legal Events

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