MX2007009760A - Polipeptidos del analogo e hibrido del peptido inhibidor gastrico con propiedades seleccionables. - Google Patents
Polipeptidos del analogo e hibrido del peptido inhibidor gastrico con propiedades seleccionables.Info
- Publication number
- MX2007009760A MX2007009760A MX2007009760A MX2007009760A MX2007009760A MX 2007009760 A MX2007009760 A MX 2007009760A MX 2007009760 A MX2007009760 A MX 2007009760A MX 2007009760 A MX2007009760 A MX 2007009760A MX 2007009760 A MX2007009760 A MX 2007009760A
- Authority
- MX
- Mexico
- Prior art keywords
- insulin
- hybrid polypeptides
- disorders
- selectable properties
- gip analog
- Prior art date
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A—HUMAN NECESSITIES
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- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P3/04—Anorexiants; Antiobesity agents
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/08—Vasodilators for multiple indications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Reproductive Health (AREA)
- Hospice & Palliative Care (AREA)
- Tropical Medicine & Parasitology (AREA)
- Neurosurgery (AREA)
- Gynecology & Obstetrics (AREA)
Abstract
La presente invencion se refiere generalmente analogos novedosos de GIP y polipeptidos del hibrido de GIP con propiedades seleccionables, utiles como agentes para el tratamiento y prevencion de enfermedades metabolicas y trastornos, por ejemplo aquellos que se pueden aliviar mediante el control de los niveles de glucosa en plasma, niveles de insulina, y/o secrecion de insulina, efectos inotropicos positivos, reduccion de los efectos catabolicos, disminucion de la velocidad del vaciado gastrico; dichas condiciones y trastornos incluyen, pero no se limitan a, hipertension, dislipidemia enfermedad cardiovascular, trastornos de la alimentacion, cuidado critico, resistencia a insulina, obesidad, y diabetes mellitus de cualquier tipo, incluyendo diabetes tipo 1, tipo 2, y diabetes gestational.
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US65266205P | 2005-02-11 | 2005-02-11 | |
US65164705P | 2005-02-11 | 2005-02-11 | |
US65343305P | 2005-02-15 | 2005-02-15 | |
US70724405P | 2005-08-11 | 2005-08-11 | |
US70736905P | 2005-08-11 | 2005-08-11 | |
US70931605P | 2005-08-17 | 2005-08-17 | |
US70932005P | 2005-08-17 | 2005-08-17 | |
PCT/US2006/005020 WO2006086769A2 (en) | 2005-02-11 | 2006-02-10 | Gip analog and hybrid polypeptides with selectable properties |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2007009760A true MX2007009760A (es) | 2007-11-07 |
Family
ID=36588963
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2007009760A MX2007009760A (es) | 2005-02-11 | 2006-02-10 | Polipeptidos del analogo e hibrido del peptido inhibidor gastrico con propiedades seleccionables. |
Country Status (14)
Country | Link |
---|---|
US (2) | US8404637B2 (es) |
EP (3) | EP1853627A2 (es) |
JP (1) | JP2008530130A (es) |
KR (1) | KR20070115947A (es) |
AU (1) | AU2006213607A1 (es) |
BR (1) | BRPI0606992A2 (es) |
CA (1) | CA2597649A1 (es) |
EA (1) | EA011653B1 (es) |
IL (1) | IL185563A0 (es) |
MX (1) | MX2007009760A (es) |
NO (1) | NO20074545L (es) |
NZ (1) | NZ561361A (es) |
SG (1) | SG159551A1 (es) |
WO (1) | WO2006086769A2 (es) |
Families Citing this family (112)
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JPS6048625A (ja) * | 1983-08-29 | 1985-03-16 | Anritsu Corp | 2重スーパヘテロダイン受信機 |
US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
US8076288B2 (en) | 2004-02-11 | 2011-12-13 | Amylin Pharmaceuticals, Inc. | Hybrid polypeptides having glucose lowering activity |
KR20070094909A (ko) * | 2004-12-02 | 2007-09-27 | 도만티스 리미티드 | 혈청 알부민 및 glp-1 또는 pyy를 표적으로 삼는이중특이성 도메인을 갖는 항체 |
US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
CA2597649A1 (en) | 2005-02-11 | 2006-08-17 | Amylin Pharmaceuticals, Inc. | Gip analog and hybrid polypeptides with selectable properties |
US8263545B2 (en) | 2005-02-11 | 2012-09-11 | Amylin Pharmaceuticals, Inc. | GIP analog and hybrid polypeptides with selectable properties |
EP1912666A2 (en) * | 2005-07-22 | 2008-04-23 | Amylin Pharmaceuticals, Inc. | Use of amylin and amylin agonists as cardioprotective or myoprotective agents |
CA2617649A1 (en) * | 2005-08-11 | 2007-02-22 | Amylin Pharmaceuticals, Inc. | Hybrid polypeptides with selectable properties |
WO2007056362A2 (en) | 2005-11-07 | 2007-05-18 | Indiana University Research And Technology Corporation | Glucagon analogs exhibiting physiological solubility and stability |
CA2638800A1 (en) * | 2006-02-22 | 2007-09-07 | Merck & Co., Inc. | Oxyntomodulin derivatives |
WO2007113205A1 (en) * | 2006-04-03 | 2007-10-11 | Novo Nordisk A/S | Glp-1 peptide agonists |
DK2049081T3 (da) | 2006-08-09 | 2013-02-25 | Intarcia Therapeutics Inc | Osmotiske leveringssystemer og stempelarrangementer |
JP5399244B2 (ja) * | 2006-08-17 | 2014-01-29 | アミリン・ファーマシューティカルズ,リミテッド・ライアビリティ・カンパニー | 選択可能な特性を持つdpp−iv耐性gipハイブリッドポリペプチド |
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EP2124974B1 (en) * | 2007-01-05 | 2017-03-15 | Indiana University Research and Technology Corporation | Glucagon analogs exhibiting enhanced solubility in physiological ph buffers |
CN101790538B (zh) | 2007-02-15 | 2014-07-30 | 印第安纳大学研究与科技公司 | 胰高血糖素/glp-1受体共激动剂 |
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WO2009015011A1 (en) * | 2007-07-20 | 2009-01-29 | Mayo Foundation For Medical Education And Research | Natriuretic polypeptides |
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EP2205265A1 (en) * | 2007-09-11 | 2010-07-14 | Mondobiotech Laboratories AG | Use of the peptide thymosin beta 4 alone or in combination with cecropin a as a therapeutic agent |
KR20100056507A (ko) * | 2007-09-11 | 2010-05-27 | 몬도바이오테크 래보래토리즈 아게 | 치료제로서의 펩티드 pro-gly-thr-cys-glu-ile-cys-ala-tyr-ala-ala-cys-thr-gly-cys의 용도 |
GB0721131D0 (en) * | 2007-10-27 | 2007-12-05 | Univ Belfast | "Peptide and users thereof" |
JP5771005B2 (ja) | 2007-10-30 | 2015-08-26 | インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation | グルカゴンアンタゴニスト及びglp−1アゴニスト活性を示す化合物 |
JP5669582B2 (ja) | 2007-10-30 | 2015-02-12 | インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation | グルカゴンアンタゴニスト |
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-
2006
- 2006-02-10 CA CA002597649A patent/CA2597649A1/en not_active Abandoned
- 2006-02-10 BR BRPI0606992-4A patent/BRPI0606992A2/pt not_active IP Right Cessation
- 2006-02-10 AU AU2006213607A patent/AU2006213607A1/en not_active Abandoned
- 2006-02-10 JP JP2007555314A patent/JP2008530130A/ja active Pending
- 2006-02-10 KR KR1020077020688A patent/KR20070115947A/ko not_active Application Discontinuation
- 2006-02-10 MX MX2007009760A patent/MX2007009760A/es unknown
- 2006-02-10 WO PCT/US2006/005020 patent/WO2006086769A2/en active Application Filing
- 2006-02-10 NZ NZ561361A patent/NZ561361A/en not_active IP Right Cessation
- 2006-02-10 US US11/816,095 patent/US8404637B2/en not_active Expired - Fee Related
- 2006-02-10 EP EP06734933A patent/EP1853627A2/en not_active Withdrawn
- 2006-02-10 EP EP20110176631 patent/EP2392595A1/en not_active Withdrawn
- 2006-02-10 SG SG201000999-1A patent/SG159551A1/en unknown
- 2006-02-10 EP EP11176629A patent/EP2390264A1/en not_active Withdrawn
- 2006-02-10 EA EA200701704A patent/EA011653B1/ru not_active IP Right Cessation
-
2007
- 2007-08-28 IL IL185563A patent/IL185563A0/en unknown
- 2007-09-07 NO NO20074545A patent/NO20074545L/no not_active Application Discontinuation
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2013
- 2013-03-25 US US13/849,933 patent/US9133260B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US8404637B2 (en) | 2013-03-26 |
WO2006086769A2 (en) | 2006-08-17 |
EA011653B1 (ru) | 2009-04-28 |
EP1853627A2 (en) | 2007-11-14 |
US20090036364A1 (en) | 2009-02-05 |
WO2006086769A3 (en) | 2006-11-02 |
NO20074545L (no) | 2007-11-09 |
US9133260B2 (en) | 2015-09-15 |
BRPI0606992A2 (pt) | 2009-07-28 |
CA2597649A1 (en) | 2006-08-17 |
JP2008530130A (ja) | 2008-08-07 |
US20130196913A1 (en) | 2013-08-01 |
NZ561361A (en) | 2010-02-26 |
SG159551A1 (en) | 2010-03-30 |
EP2392595A1 (en) | 2011-12-07 |
EA200701704A1 (ru) | 2008-02-28 |
IL185563A0 (en) | 2008-01-06 |
AU2006213607A1 (en) | 2006-08-17 |
EP2390264A1 (en) | 2011-11-30 |
KR20070115947A (ko) | 2007-12-06 |
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