MX2007002833A - Derivados de alquiliden-tetrahidronaftaleno, procedimiento para su preparacion y su uso como antiinflamatorios. - Google Patents

Derivados de alquiliden-tetrahidronaftaleno, procedimiento para su preparacion y su uso como antiinflamatorios.

Info

Publication number
MX2007002833A
MX2007002833A MX2007002833A MX2007002833A MX2007002833A MX 2007002833 A MX2007002833 A MX 2007002833A MX 2007002833 A MX2007002833 A MX 2007002833A MX 2007002833 A MX2007002833 A MX 2007002833A MX 2007002833 A MX2007002833 A MX 2007002833A
Authority
MX
Mexico
Prior art keywords
alkylidene
production
inflammatory agents
tetrahydronaphthalene derivatives
tetrahydronaphthalene
Prior art date
Application number
MX2007002833A
Other languages
English (en)
Inventor
Stefan Baurle
Markus Berger
Stefan Jaroch
Konrad Krolikiewicz
Duy Nguyen
Hartmut Rehwinkel
Heike Schacke
Norbert Schmees
Werner Skuballa
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of MX2007002833A publication Critical patent/MX2007002833A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734—Ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/84—Nitrogen atoms

Abstract

La presente invencion se refiere a derivados de alquiliden-tetrahidronaftaleno de la formula general I, procedimiento para su preparacion y su uso como antiinflamatorios.
MX2007002833A 2004-09-09 2005-09-02 Derivados de alquiliden-tetrahidronaftaleno, procedimiento para su preparacion y su uso como antiinflamatorios. MX2007002833A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004044680A DE102004044680B3 (de) 2004-09-09 2004-09-09 Alkyliden-Tetrahydronaphthalinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer sowie diese enthaltende pharmazeutische Präparate
PCT/EP2005/009623 WO2006027236A1 (de) 2004-09-09 2005-09-02 Alkyliden-tetrahydronaphthalinderivate, verfahren zu ihrer herstellung und ihre verwendung als entzündungshemmer

Publications (1)

Publication Number Publication Date
MX2007002833A true MX2007002833A (es) 2007-07-09

Family

ID=35517445

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007002833A MX2007002833A (es) 2004-09-09 2005-09-02 Derivados de alquiliden-tetrahidronaftaleno, procedimiento para su preparacion y su uso como antiinflamatorios.

Country Status (25)

Country Link
EP (1) EP1786823B1 (es)
JP (1) JP2008512416A (es)
KR (1) KR20070050469A (es)
CN (1) CN101065386A (es)
AR (1) AR050733A1 (es)
AT (1) ATE384069T1 (es)
AU (1) AU2005281859A1 (es)
BR (1) BRPI0515186A (es)
CA (1) CA2577861A1 (es)
DE (2) DE102004044680B3 (es)
EA (1) EA200700550A1 (es)
EC (1) ECSP077306A (es)
ES (1) ES2301056T3 (es)
GT (1) GT200500241A (es)
IL (1) IL181832A0 (es)
MX (1) MX2007002833A (es)
NO (1) NO20071805L (es)
PA (1) PA8644701A1 (es)
PE (1) PE20060596A1 (es)
RS (1) RS20070095A (es)
SV (1) SV2006002220A (es)
TW (1) TW200621703A (es)
UY (1) UY29109A1 (es)
WO (1) WO2006027236A1 (es)
ZA (1) ZA200701399B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7638515B2 (en) 2003-10-08 2009-12-29 Bayer Schering Pharma Aktiengesellschaft Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents
ES2279454T3 (es) 2003-10-08 2007-08-16 Bayer Schering Pharma Aktiengesellschaft Derivados de tetrahidronaftaleno sustituidos con 1-amino-2-oxi, procedimientos para su preparacion y su utilizacion como anti-inflamatorios.
US7662821B2 (en) 2003-10-08 2010-02-16 Bayer Schering Pharma Ag Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents
US20080153859A1 (en) 2004-04-05 2008-06-26 Hartmut Rehwinkel Multiply-substituted tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents
DE102004063227A1 (de) * 2004-12-22 2006-07-06 Schering Ag Tricylische Aminoalkohole, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer
EP1834948A1 (de) 2006-03-15 2007-09-19 Bayer Schering Pharma Aktiengesellschaft Tetrahydronaphthalinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer
EP1917963A1 (en) * 2006-10-31 2008-05-07 Bayer Schering Pharma Aktiengesellschaft Cyclic phenyl-substituted indazols, a process for their production and their use as anti-inflammatory agents
EP2129219A4 (en) * 2007-02-16 2012-08-29 Synta Pharmaceuticals Corp SUBSTITUTED FUSED CYCLE COMPOUNDS USED IN CASES OF INFLAMMATION OR IMMUNE DISORDERS
EP2072509A1 (en) 2007-12-18 2009-06-24 Bayer Schering Pharma Aktiengesellschaft 1-Aryl-1H-quinoline-2-ones: process for their production and their use as anti-inflammatory agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0800517A1 (en) * 1994-12-29 1997-10-15 Allergan Acetylenes disubstituted with a 5 or 8 substituted tetrahydronaphthyl or dihydronaphthyl group and with an aryl or heteroaryl groups having retinoid-like biological activity
DE10038639A1 (de) * 2000-07-28 2002-02-21 Schering Ag Nichtsteroidale Entzündungshemmer
EA008830B1 (ru) * 2002-03-26 2007-08-31 Бёрингер Ингельхайм Фармасьютиклз, Инк. Миметики глюкокортикоидов, способы их получения, фармацевтические композиции и их применение
DE10215316C1 (de) * 2002-04-02 2003-12-18 Schering Ag Chinolin- und Isochinolin-Derivate, ein pharmazeutisches Mittel und ihre Verwendung als Entzündungshemmer
ES2279454T3 (es) * 2003-10-08 2007-08-16 Bayer Schering Pharma Aktiengesellschaft Derivados de tetrahidronaftaleno sustituidos con 1-amino-2-oxi, procedimientos para su preparacion y su utilizacion como anti-inflamatorios.

Also Published As

Publication number Publication date
AR050733A1 (es) 2006-11-15
TW200621703A (en) 2006-07-01
EP1786823A1 (de) 2007-05-23
ECSP077306A (es) 2007-04-26
PA8644701A1 (es) 2006-07-03
RS20070095A (en) 2008-11-28
DE102004044680B3 (de) 2006-06-08
EA200700550A1 (ru) 2007-10-26
IL181832A0 (en) 2007-07-04
DE502005002595D1 (de) 2008-03-06
ATE384069T1 (de) 2008-02-15
CA2577861A1 (en) 2006-03-16
AU2005281859A1 (en) 2006-03-16
UY29109A1 (es) 2006-03-31
WO2006027236A1 (de) 2006-03-16
KR20070050469A (ko) 2007-05-15
SV2006002220A (es) 2006-03-15
ES2301056T3 (es) 2008-06-16
BRPI0515186A (pt) 2008-07-22
PE20060596A1 (es) 2006-07-26
NO20071805L (no) 2007-06-07
CN101065386A (zh) 2007-10-31
JP2008512416A (ja) 2008-04-24
GT200500241A (es) 2006-08-17
ZA200701399B (en) 2008-09-25
EP1786823B1 (de) 2008-01-16

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Legal Events

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