ME03599B - Biciklički kondenzirani heteroarilni ili arilni spojevi i njihova upotreba kao inhibitora irak4 - Google Patents

Biciklički kondenzirani heteroarilni ili arilni spojevi i njihova upotreba kao inhibitora irak4

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Publication number
ME03599B
ME03599B MEP-2019-113A MEP2019113A ME03599B ME 03599 B ME03599 B ME 03599B ME P2019113 A MEP2019113 A ME P2019113A ME 03599 B ME03599 B ME 03599B
Authority
ME
Montenegro
Prior art keywords
bicyclic
fused heteroaryl
aryl compounds
irak4 inhibitors
irak4
Prior art date
Application number
MEP-2019-113A
Other languages
German (de)
English (en)
French (fr)
Inventor
Betsy PIERCE
Eddine Saiah
John David Trzupek
David Hepworth
Christoph Wolfgang Zapf
David Randolph Anderson
Mark Edward Bunnage
Kevin Joseph Curran
Christoph Martin Dehnhardt
Lori Krim Gavrin
Joel Adam Goldberg
Seungil Han
Horng-Chih Huang
Arthur Lee
Katherine Lin Lee
Frank Eldridge Lovering
Michael Dennis Lowe
John Paul Mathias
Nikolaos Papaioannou
Akshay Patny
Joseph Walter Strohbach
Richard Vargas
Xiaolun Wang
Stephen Wayne Wright
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ME03599B publication Critical patent/ME03599B/me

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    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
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