MD960317A - Noile peptide-agoniste ale amilinei şi utilizarea lor - Google Patents
Noile peptide-agoniste ale amilinei şi utilizarea lorInfo
- Publication number
- MD960317A MD960317A MD96-0317A MD960317A MD960317A MD 960317 A MD960317 A MD 960317A MD 960317 A MD960317 A MD 960317A MD 960317 A MD960317 A MD 960317A
- Authority
- MD
- Moldova
- Prior art keywords
- amylin agonist
- uses therefor
- agonist peptides
- novel amylin
- novel
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Immunology (AREA)
- Emergency Medicine (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Sunt revendicaţi analogi agonişti ai amilinei şi compoziţii farmaceutice pe baza lor, procedee de tratament al diabetului şi altor stări ce necesită insulină, precum şi procedee de tratament al hipoglicemiei.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US79426691A | 1991-11-19 | 1991-11-19 | |
PCT/US1992/009842 WO1993010146A1 (en) | 1991-11-19 | 1992-11-19 | Amylin agonist peptides and uses therefor |
Publications (1)
Publication Number | Publication Date |
---|---|
MD960317A true MD960317A (ro) | 1998-05-31 |
Family
ID=25162163
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MD96-0317A MD960317A (ro) | 1991-11-19 | 1992-11-19 | Noile peptide-agoniste ale amilinei şi utilizarea lor |
Country Status (17)
Country | Link |
---|---|
EP (2) | EP1162207A1 (ro) |
JP (4) | JP2902115B2 (ro) |
AT (1) | ATE205854T1 (ro) |
AU (1) | AU714439B2 (ro) |
CA (1) | CA2100745C (ro) |
CZ (1) | CZ288029B6 (ro) |
DE (1) | DE69232064T2 (ro) |
DK (1) | DK0567626T3 (ro) |
ES (1) | ES2161697T3 (ro) |
FI (1) | FI118601B (ro) |
GR (1) | GR3036794T3 (ro) |
HK (1) | HK1041891A1 (ro) |
MD (1) | MD960317A (ro) |
NO (2) | NO324405B1 (ro) |
RU (1) | RU2130463C1 (ro) |
SK (1) | SK88793A3 (ro) |
WO (1) | WO1993010146A1 (ro) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU222249B1 (hu) | 1991-03-08 | 2003-05-28 | Amylin Pharmaceuticals Inc. | Eljárás amilin agonista peptidszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására |
US5625032A (en) * | 1993-07-21 | 1997-04-29 | Amylin Pharmaceuticals, Inc. | Selective amylin antagonist peptides and uses therefor |
DE69426304T2 (de) | 1993-09-07 | 2001-03-15 | Amylin Pharmaceuticals Inc | Methoden zur regulation der den magen und darm betreffenden motilitaet |
US6143718A (en) * | 1995-06-07 | 2000-11-07 | Amylin Pharmaceuticals, Inc. | Treatment of Type II diabetes mellutis with amylin agonists |
US5739106A (en) * | 1995-06-07 | 1998-04-14 | Rink; Timothy J. | Appetite regulating compositions |
US7312196B2 (en) | 1997-01-08 | 2007-12-25 | Amylin Pharmaceuticals, Inc. | Formulations for amylin agonist peptides |
US6410511B2 (en) | 1997-01-08 | 2002-06-25 | Amylin Pharmaceuticals, Inc. | Formulations for amylin agonist peptides |
US7101853B2 (en) * | 1997-05-06 | 2006-09-05 | Amylin Pharmaceuticals, Inc. | Method for treating or preventing gastritis using amylin or amylin agonists |
US7910548B2 (en) | 1997-06-06 | 2011-03-22 | Amylin Pharmaceuticals, Inc. | Methods for treating obesity |
ATE410182T1 (de) * | 1998-01-09 | 2008-10-15 | Amylin Pharmaceuticals Inc | Formulierungen für amylin peptidagonisten mit insulin |
GB0128583D0 (en) | 2001-11-28 | 2002-01-23 | Rsr Ltd | Detection of autoantibodies indicative of diabetes |
WO2004037168A2 (en) | 2002-10-18 | 2004-05-06 | Amylin Pharmaceuticals, Inc. | Treatment of pancreatitis with amylin |
WO2004083243A1 (en) * | 2003-03-18 | 2004-09-30 | Applied Research Systems Ars Holding N.V. | Amylin aggregation inhibitors and use thereof. |
EP1807442A1 (en) * | 2004-10-26 | 2007-07-18 | Lonza Ag | S-alkyl-sulphenyl protection groups in solid-phase synthesis |
US8394765B2 (en) | 2004-11-01 | 2013-03-12 | Amylin Pharmaceuticals Llc | Methods of treating obesity with two different anti-obesity agents |
EP2286838A3 (en) | 2004-11-01 | 2013-09-04 | Amylin Pharmaceuticals, LLC | Treatment of obesity and related disorders |
EA013121B1 (ru) | 2005-03-31 | 2010-02-26 | Амилин Фармасьютикалз, Инк. | Амилин и агонисты амилина для лечения психиатрических заболеваний и расстройств |
US8168592B2 (en) | 2005-10-21 | 2012-05-01 | Amgen Inc. | CGRP peptide antagonists and conjugates |
JP2010502670A (ja) | 2006-09-07 | 2010-01-28 | ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング | 真性糖尿病のための組合せ治療 |
EP2120985B1 (en) | 2007-02-05 | 2012-06-27 | Amylin Pharmaceuticals, Inc. | FN-38 peptides for use in the treatment of psychotic and anxiety disorders |
JP2009149684A (ja) * | 2009-03-11 | 2009-07-09 | Amylin Pharmaceut Inc | アミリン作動薬ペプチド用製剤 |
KR101673042B1 (ko) | 2009-03-12 | 2016-11-04 | 키바이오사이언스 아게 | 당뇨병 및 대사 증후군의 치료 |
AR097701A1 (es) * | 2013-09-19 | 2016-04-13 | Zealand Pharma As | Análogos de amilina |
CA2928725A1 (en) | 2013-11-05 | 2015-05-14 | Esther Priel | Compounds for the treatment of diabetes and disease complications arising from same |
DK3137494T3 (da) * | 2014-05-02 | 2021-10-04 | Univ New York State Res Found | Isletamyloidpolypeptider med forbedret opløselighed |
EA035791B1 (ru) | 2015-03-18 | 2020-08-11 | Зилэнд Фарма А/С | Аналоги амилина |
US10071140B2 (en) | 2016-09-09 | 2018-09-11 | Zealand Pharma A/S | Amylin analogues |
WO2018144671A1 (en) | 2017-02-01 | 2018-08-09 | The Research Foundation For The State University Of New York | Mutant islet amyloid polypeptides with improved solubility and methods for using the same |
KR102130354B1 (ko) * | 2019-08-14 | 2020-07-06 | 엘아이지넥스원 주식회사 | 코어 제거용 이형장치 |
AU2023278353A1 (en) | 2022-05-30 | 2024-05-23 | Zealand Pharma A/S | Liquid formulations of amylin analogues |
WO2024061919A1 (en) | 2022-09-19 | 2024-03-28 | Zealand Pharma A/S | Combination therapy |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8720115D0 (en) * | 1987-08-26 | 1987-09-30 | Cooper G J S | Treatment of diabetes mellitus |
WO1989006135A1 (en) * | 1988-01-11 | 1989-07-13 | Amylin Corporation | Treatment of type 2 diabetes mellitus |
WO1991000737A1 (en) * | 1989-07-10 | 1991-01-24 | Amylin Corporation | Treatment of obesity and essential hypertension and related disorders |
US5234906A (en) * | 1991-01-10 | 1993-08-10 | Amylin Pharmaceuticals, Inc. | Hyperglycemic compositions |
WO1992015317A1 (en) * | 1991-03-08 | 1992-09-17 | Amylin Pharmaceuticals, Inc. | Synthetic preparation of amylin and amylin analogues |
-
1992
- 1992-11-19 MD MD96-0317A patent/MD960317A/ro unknown
- 1992-11-19 DK DK92924442T patent/DK0567626T3/da active
- 1992-11-19 CZ CZ19931689A patent/CZ288029B6/cs not_active IP Right Cessation
- 1992-11-19 EP EP01114132A patent/EP1162207A1/en not_active Ceased
- 1992-11-19 EP EP92924442A patent/EP0567626B1/en not_active Expired - Lifetime
- 1992-11-19 JP JP5509441A patent/JP2902115B2/ja not_active Expired - Lifetime
- 1992-11-19 WO PCT/US1992/009842 patent/WO1993010146A1/en active IP Right Grant
- 1992-11-19 RU RU93053497A patent/RU2130463C1/ru active
- 1992-11-19 CA CA002100745A patent/CA2100745C/en not_active Expired - Lifetime
- 1992-11-19 SK SK887-93A patent/SK88793A3/sk unknown
- 1992-11-19 ES ES92924442T patent/ES2161697T3/es not_active Expired - Lifetime
- 1992-11-19 AT AT92924442T patent/ATE205854T1/de active
- 1992-11-19 DE DE69232064T patent/DE69232064T2/de not_active Expired - Lifetime
-
1993
- 1993-07-16 FI FI933252A patent/FI118601B/fi not_active IP Right Cessation
- 1993-07-19 NO NO19932603A patent/NO324405B1/no not_active IP Right Cessation
-
1997
- 1997-01-31 AU AU12456/97A patent/AU714439B2/en not_active Expired
-
1998
- 1998-09-30 JP JP10277573A patent/JPH11152299A/ja not_active Withdrawn
-
2001
- 2001-10-04 GR GR20010401656T patent/GR3036794T3/el unknown
-
2002
- 2002-05-02 HK HK02103291.8A patent/HK1041891A1/zh unknown
-
2003
- 2003-01-15 JP JP2003007228A patent/JP2003238594A/ja not_active Withdrawn
-
2006
- 2006-02-03 JP JP2006027334A patent/JP4018116B2/ja not_active Expired - Lifetime
-
2007
- 2007-06-25 NO NO20073265A patent/NO20073265L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CZ168993A3 (en) | 1994-04-13 |
CA2100745C (en) | 2007-07-31 |
HK1041891A1 (zh) | 2002-07-26 |
EP0567626A1 (en) | 1993-11-03 |
JP2003238594A (ja) | 2003-08-27 |
DE69232064D1 (de) | 2001-10-25 |
DK0567626T3 (da) | 2001-12-17 |
NO932603D0 (no) | 1993-07-19 |
JP2006213716A (ja) | 2006-08-17 |
JP2902115B2 (ja) | 1999-06-07 |
NO324405B1 (no) | 2007-10-08 |
JPH06504794A (ja) | 1994-06-02 |
AU1245697A (en) | 1997-03-27 |
ATE205854T1 (de) | 2001-10-15 |
ES2161697T3 (es) | 2001-12-16 |
AU3075392A (en) | 1993-06-15 |
EP1162207A1 (en) | 2001-12-12 |
GR3036794T3 (en) | 2002-01-31 |
CA2100745A1 (en) | 1993-05-20 |
JPH11152299A (ja) | 1999-06-08 |
NO20073265L (no) | 1993-09-17 |
FI933252A (fi) | 1993-08-23 |
RU2130463C1 (ru) | 1999-05-20 |
AU714439B2 (en) | 2000-01-06 |
FI933252A0 (fi) | 1993-07-16 |
WO1993010146A1 (en) | 1993-05-27 |
JP4018116B2 (ja) | 2007-12-05 |
CZ288029B6 (cs) | 2001-04-11 |
FI118601B (fi) | 2008-01-15 |
SK88793A3 (en) | 1994-12-07 |
DE69232064T2 (de) | 2002-03-28 |
NO932603L (no) | 1993-09-17 |
EP0567626B1 (en) | 2001-09-19 |
AU673147B2 (en) | 1996-10-31 |
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