MA51705A - Biomarqueur prédictif de la thérapie des lymphocytes infiltrant les tumeurs et ses utilisations - Google Patents

Biomarqueur prédictif de la thérapie des lymphocytes infiltrant les tumeurs et ses utilisations

Info

Publication number
MA51705A
MA51705A MA051705A MA51705A MA51705A MA 51705 A MA51705 A MA 51705A MA 051705 A MA051705 A MA 051705A MA 51705 A MA51705 A MA 51705A MA 51705 A MA51705 A MA 51705A
Authority
MA
Morocco
Prior art keywords
tumhocyte
predictive biomarker
infiltration
therapy
infiltration therapy
Prior art date
Application number
MA051705A
Other languages
English (en)
Inventor
John Stephen Bridgeman
Nicola Kaye Price
Original Assignee
Instil Bio Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instil Bio Uk Ltd filed Critical Instil Bio Uk Ltd
Publication of MA51705A publication Critical patent/MA51705A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • A61K39/46449—Melanoma antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/599—Cell markers; Cell surface determinants with CD designations not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/65—MicroRNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Developmental Biology & Embryology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
MA051705A 2018-01-23 2019-01-23 Biomarqueur prédictif de la thérapie des lymphocytes infiltrant les tumeurs et ses utilisations MA51705A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1801067.8A GB201801067D0 (en) 2018-01-23 2018-01-23 Biomarkers predictive of tumour infiltrating lymphocyte therapy and uses thereof

Publications (1)

Publication Number Publication Date
MA51705A true MA51705A (fr) 2020-12-02

Family

ID=61283558

Family Applications (1)

Application Number Title Priority Date Filing Date
MA051705A MA51705A (fr) 2018-01-23 2019-01-23 Biomarqueur prédictif de la thérapie des lymphocytes infiltrant les tumeurs et ses utilisations

Country Status (22)

Country Link
US (1) US20210000872A1 (fr)
EP (2) EP4233883A3 (fr)
JP (1) JP2021511079A (fr)
KR (1) KR20200112915A (fr)
CN (1) CN111886335A (fr)
AU (1) AU2019213201A1 (fr)
BR (1) BR112020014998A2 (fr)
CA (1) CA3089294A1 (fr)
CL (1) CL2020001943A1 (fr)
CO (1) CO2020010266A2 (fr)
CR (1) CR20200361A (fr)
EA (1) EA202091753A1 (fr)
EC (1) ECSP20050981A (fr)
ES (1) ES2948969T3 (fr)
GB (1) GB201801067D0 (fr)
IL (1) IL276167A (fr)
MA (1) MA51705A (fr)
MX (1) MX2020007728A (fr)
PE (1) PE20210843A1 (fr)
PH (1) PH12020551110A1 (fr)
SG (1) SG11202006875VA (fr)
WO (1) WO2019145711A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201700621D0 (en) 2017-01-13 2017-03-01 Guest Ryan Dominic Method,device and kit for the aseptic isolation,enrichment and stabilsation of cells from mammalian solid tissue
GB201910605D0 (en) * 2019-07-24 2019-09-04 Immetacyte Ltd Tumour infltracting lymphocyte therapy amd uses thereo
KR20220119439A (ko) 2019-12-20 2022-08-29 인스틸 바이오 유케이 리미티드 종양 침윤 림프구를 분리하기 위한 장치 및 방법 및 그것의 용도
WO2022130017A2 (fr) 2020-12-18 2022-06-23 Instil Bio (Uk) Limited Traitement de lymphocytes infiltrant les tumeurs
WO2022130015A2 (fr) 2020-12-18 2022-06-23 Instil Bio (Uk) Limited Traitement de lymphocytes infiltrant les tumeurs
WO2022130016A1 (fr) 2020-12-18 2022-06-23 Instil Bio (Uk) Limited Lymphocytes infiltrant les tumeurs et agents thérapeutiques anti-cd47
US20220313806A1 (en) 2021-03-25 2022-10-06 Iovance Biotherapeutics, Inc. Methods and compositions for t-cell coculture potency assays and use with cell therapy products

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1086501A (en) 1999-10-15 2001-04-30 Carnegie Institution Of Washington Rna interference pathway genes as tools for targeted genetic interference
US6326193B1 (en) 1999-11-05 2001-12-04 Cambria Biosciences, Llc Insect control agent
AU2001275474A1 (en) 2000-06-12 2001-12-24 Akkadix Corporation Materials and methods for the control of nematodes
EP1777523A1 (fr) 2005-10-19 2007-04-25 INSERM (Institut National de la Santé et de la Recherche Médicale) Méthode pour pronostiquer la progression d'un cancer et les résultats du patient et les moyens pour performer la méthode
KR20160002971A (ko) * 2013-04-18 2016-01-08 틸트 바이오세러퓨틱스 오이 향상된 입양 세포 치료
EP3119477B1 (fr) * 2014-03-20 2020-01-01 H. Lee Moffitt Cancer Center And Research Institute, Inc. Lymphocytes infiltrant les tumeurs pour thérapie cellulaire adoptive
WO2017179015A1 (fr) * 2016-04-15 2017-10-19 Glaxosmithkline Intellectual Property Development Limited Compositions pour le traitement du cancer

Also Published As

Publication number Publication date
AU2019213201A1 (en) 2020-08-06
PH12020551110A1 (en) 2021-07-05
EP3743511A1 (fr) 2020-12-02
CR20200361A (es) 2021-01-13
BR112020014998A2 (pt) 2020-12-29
SG11202006875VA (en) 2020-08-28
EP3743511C0 (fr) 2023-06-07
EP3743511B1 (fr) 2023-06-07
MX2020007728A (es) 2020-10-05
EP4233883A3 (fr) 2023-10-11
WO2019145711A1 (fr) 2019-08-01
CA3089294A1 (fr) 2019-08-01
IL276167A (en) 2020-09-30
KR20200112915A (ko) 2020-10-05
EA202091753A1 (ru) 2020-09-23
EP4233883A2 (fr) 2023-08-30
CN111886335A (zh) 2020-11-03
US20210000872A1 (en) 2021-01-07
ECSP20050981A (es) 2021-01-29
CL2020001943A1 (es) 2021-02-26
CO2020010266A2 (es) 2020-10-30
GB201801067D0 (en) 2018-03-07
PE20210843A1 (es) 2021-05-10
ES2948969T3 (es) 2023-09-22
JP2021511079A (ja) 2021-05-06

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