MA50279A - Enrichissement de cellules coexprimant nkx6.1 et le peptide c, dérivées in vitro à partir de cellules souches - Google Patents

Enrichissement de cellules coexprimant nkx6.1 et le peptide c, dérivées in vitro à partir de cellules souches

Info

Publication number
MA50279A
MA50279A MA050279A MA50279A MA50279A MA 50279 A MA50279 A MA 50279A MA 050279 A MA050279 A MA 050279A MA 50279 A MA50279 A MA 50279A MA 50279 A MA50279 A MA 50279A
Authority
MA
Morocco
Prior art keywords
cells
enrichment
expressing
peptide
stem cells
Prior art date
Application number
MA050279A
Other languages
English (en)
Inventor
Allé Novo
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of MA50279A publication Critical patent/MA50279A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0676Pancreatic cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0676Pancreatic cells
    • C12N5/0677Three-dimensional culture, tissue culture or organ culture; Encapsulated cells
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0278Physical preservation processes
    • A01N1/0284Temperature processes, i.e. using a designated change in temperature over time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37Digestive system
    • A61K35/39Pancreas; Islets of Langerhans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00Methods for the dissociation of cells, e.g. specific use of enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2523/00Culture process characterised by temperature

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Physiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
MA050279A 2017-09-11 2018-09-11 Enrichissement de cellules coexprimant nkx6.1 et le peptide c, dérivées in vitro à partir de cellules souches MA50279A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP17190412 2017-09-11

Publications (1)

Publication Number Publication Date
MA50279A true MA50279A (fr) 2020-07-22

Family

ID=59846503

Family Applications (1)

Application Number Title Priority Date Filing Date
MA050279A MA50279A (fr) 2017-09-11 2018-09-11 Enrichissement de cellules coexprimant nkx6.1 et le peptide c, dérivées in vitro à partir de cellules souches

Country Status (15)

Country Link
US (1) US20200199540A1 (fr)
EP (1) EP3681992A1 (fr)
JP (1) JP7389020B2 (fr)
KR (1) KR20200051664A (fr)
CN (1) CN111108190A (fr)
AU (1) AU2018330499A1 (fr)
BR (1) BR112020004428A2 (fr)
CA (1) CA3074910A1 (fr)
CO (1) CO2020003122A2 (fr)
IL (1) IL272734A (fr)
MA (1) MA50279A (fr)
MX (1) MX2020002421A (fr)
RU (1) RU2020111055A (fr)
SG (1) SG11202001906PA (fr)
WO (1) WO2019048690A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113728090B (zh) 2019-04-08 2024-04-05 诺和诺德股份有限公司 从干细胞衍生的定形内胚层生成胰腺内胚层
EP4061929A1 (fr) 2019-11-22 2022-09-28 Novo Nordisk A/S Microsphères neuronales regroupée par rotation et application associée
WO2023203208A1 (fr) 2022-04-21 2023-10-26 Evotec International Gmbh Nouvelles populations de cellules et moyens et procédés pour leur différenciation et leur conservation
WO2024008810A1 (fr) 2022-07-06 2024-01-11 Novo Nordisk A/S Différenciation de cellules souches en cellules endocrines pancréatiques

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2018638C (fr) * 1990-06-08 2002-10-01 Wah Jun Tze Mise en banque de cellules endocrines de pancreas pour les transplantations
WO2003055992A2 (fr) 2001-12-28 2003-07-10 Cellartis Ab Methode permettant d'etablir une lignee de cellules souches hematopoietiques multipotentes humaines derivees du blastocyste
GB2445338A (en) 2005-10-07 2008-07-02 Cellartis Ab A method for obtaining a xeno-free HBS cell line
US7695965B2 (en) * 2006-03-02 2010-04-13 Cythera, Inc. Methods of producing pancreatic hormones
US9080145B2 (en) * 2007-07-01 2015-07-14 Lifescan Corporation Single pluripotent stem cell culture
CA3229301A1 (fr) * 2008-11-14 2010-05-20 Viacyte, Inc. Encapsulation de cellules pancreatiques derivees de cellules souches pluripotentes humaines
WO2011109279A2 (fr) * 2010-03-01 2011-09-09 Centocor Ortho Biotech Inc. Procédés de purification de cellules issues de cellules souches pluripotentes
CN103890167A (zh) 2011-06-21 2014-06-25 诺沃—诺迪斯克有限公司 自多潜能干细胞有效诱导定形内胚层
EP2893000B1 (fr) 2012-09-03 2019-04-10 Novo Nordisk A/S Génération d'endoderme pancréatique à partir de cellules souches pluripotentes à l'aide de petites molécules
US10377989B2 (en) 2012-12-31 2019-08-13 Janssen Biotech, Inc. Methods for suspension cultures of human pluripotent stem cells
WO2014138671A2 (fr) * 2013-03-08 2014-09-12 Viacyte, Inc. Cryopréservation, hibernation et stockage à température ambiante d'agrégats de cellules endodermiques pancréatiques encapsulés
US8859286B2 (en) * 2013-03-14 2014-10-14 Viacyte, Inc. In vitro differentiation of pluripotent stem cells to pancreatic endoderm cells (PEC) and endocrine cells
DK3039122T3 (da) 2013-08-30 2019-09-30 Novo Nordisk As Generering af endokrine progenitorceller fra humane pluripotente stamceller under anvendelse af små molekyler
JP2017112835A (ja) * 2014-04-17 2017-06-29 東京エレクトロン株式会社 多能性幹細胞の凍結保存方法および凍結保存システム
BR112018010946A2 (pt) * 2015-11-30 2018-12-04 Kadimastem Ltd método para enriquecimento de células endócrinas pancreáticas, população enriquecida de células endócrinas pancreáticas, método de tratamento de diabetes e método de preparação de células beta de produção de insulina
WO2017144695A1 (fr) 2016-02-24 2017-08-31 Novo Nordisk A/S Génération de cellules bêta fonctionnelles à partir de progéniteurs endocrines dérivés de cellules souches pluripotentes humaines

Also Published As

Publication number Publication date
CA3074910A1 (fr) 2019-03-14
WO2019048690A1 (fr) 2019-03-14
KR20200051664A (ko) 2020-05-13
JP2020532978A (ja) 2020-11-19
CO2020003122A2 (es) 2020-06-19
SG11202001906PA (en) 2020-04-29
CN111108190A (zh) 2020-05-05
BR112020004428A2 (pt) 2020-09-08
RU2020111055A (ru) 2021-09-17
US20200199540A1 (en) 2020-06-25
AU2018330499A1 (en) 2020-04-09
EP3681992A1 (fr) 2020-07-22
IL272734A (en) 2020-04-30
MX2020002421A (es) 2020-07-13
JP7389020B2 (ja) 2023-11-29
RU2020111055A3 (fr) 2022-04-22

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