MA50156A - Variants d'anticorps - Google Patents

Variants d'anticorps

Info

Publication number
MA50156A
MA50156A MA050156A MA50156A MA50156A MA 50156 A MA50156 A MA 50156A MA 050156 A MA050156 A MA 050156A MA 50156 A MA50156 A MA 50156A MA 50156 A MA50156 A MA 50156A
Authority
MA
Morocco
Prior art keywords
antibody variants
variants
antibody
Prior art date
Application number
MA050156A
Other languages
English (en)
Inventor
Esther Maria Furrer
Original Assignee
Tillotts Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=59923275&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA50156(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Tillotts Pharma Ag filed Critical Tillotts Pharma Ag
Publication of MA50156A publication Critical patent/MA50156A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241Tumor Necrosis Factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/40Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41Glycosylation, sialylation, or fucosylation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/72Increased effector function due to an Fc-modification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732Antibody-dependent cellular cytotoxicity [ADCC]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734Complement-dependent cytotoxicity [CDC]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/74Inducing cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77Internalization into the cell
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
MA050156A 2017-09-19 2018-09-11 Variants d'anticorps MA50156A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP17191989.7A EP3456738A1 (fr) 2017-09-19 2017-09-19 Variantes d'anticorps

Publications (1)

Publication Number Publication Date
MA50156A true MA50156A (fr) 2020-07-29

Family

ID=59923275

Family Applications (1)

Application Number Title Priority Date Filing Date
MA050156A MA50156A (fr) 2017-09-19 2018-09-11 Variants d'anticorps

Country Status (21)

Country Link
EP (2) EP3456738A1 (fr)
JP (2) JP7240385B2 (fr)
KR (1) KR20200053514A (fr)
CN (1) CN111094343A (fr)
AR (1) AR113303A1 (fr)
AU (1) AU2018337495A1 (fr)
BR (1) BR112020005482A2 (fr)
CA (1) CA3075959A1 (fr)
CL (1) CL2020000721A1 (fr)
CO (1) CO2020003260A2 (fr)
CR (2) CR20200132A (fr)
EA (1) EA202090617A1 (fr)
GE (1) GEP20237484B (fr)
IL (1) IL273351A (fr)
JO (1) JOP20200063A1 (fr)
MA (1) MA50156A (fr)
MX (1) MX2020002989A (fr)
PH (1) PH12020500473A1 (fr)
SG (1) SG11202002220TA (fr)
TW (1) TW201915021A (fr)
WO (1) WO2019057564A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2019001458A (es) 2016-08-02 2019-07-04 Visterra Inc Polipeptidos modificados y usos de los mismos.
WO2020114616A1 (fr) 2018-12-07 2020-06-11 Tillotts Pharma Ag Traitement topique d'une diarrhée, d'une colite ou d'une entérocolite induite par un inhibiteur de point de contrôle immunitaire au moyen d'anticorps et de fragments de ceux-ci

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2348051T3 (en) * 2003-11-05 2019-03-18 Roche Glycart Ag CD20 antibodies with increased fc receptor binding affinity and effector function
CA2595112A1 (fr) 2004-12-31 2006-07-13 Genentech, Inc. Polypeptides de liaison a la br3 et leurs utilisations
CA3086659A1 (fr) 2007-12-26 2009-07-09 Xencor, Inc. Variants de fc avec une liaison alteree a fcrn
CN107936117B (zh) 2008-06-25 2022-12-23 诺华股份有限公司 抑制TNFα的稳定和可溶的抗体
WO2015158867A1 (fr) 2014-04-16 2015-10-22 Ucb Biopharma Sprl Protéines fc multimères
CR20180365A (es) 2015-12-16 2018-09-28 Amgen Inc PROTEÍNAS DE UNIÓN AL ANTÍGENO BISPECÍFICO DE ANTI-TL1A/ANTI-TNF-a Y SUS USOS
US11319383B2 (en) * 2016-03-14 2022-05-03 Universitetet | Oslo Engineered immunoglobulins with altered FcRn binding

Also Published As

Publication number Publication date
IL273351A (en) 2020-05-31
EP3456738A1 (fr) 2019-03-20
SG11202002220TA (en) 2020-04-29
GEP20237484B (en) 2023-03-27
US20200216527A1 (en) 2020-07-09
PH12020500473A1 (en) 2021-01-25
JP7402304B2 (ja) 2023-12-20
CR20200132A (es) 2020-07-24
JP2020534307A (ja) 2020-11-26
CL2020000721A1 (es) 2020-08-07
BR112020005482A2 (pt) 2020-09-29
CO2020003260A2 (es) 2020-04-13
CN111094343A (zh) 2020-05-01
AU2018337495A1 (en) 2020-04-09
EA202090617A1 (ru) 2020-07-27
WO2019057564A1 (fr) 2019-03-28
JP7240385B2 (ja) 2023-03-15
KR20200053514A (ko) 2020-05-18
TW201915021A (zh) 2019-04-16
AR113303A1 (es) 2020-04-08
JOP20200063A1 (ar) 2020-03-17
CA3075959A1 (fr) 2019-03-28
EP3684807A1 (fr) 2020-07-29
JP2023036885A (ja) 2023-03-14
CR20210205A (es) 2021-07-27
MX2020002989A (es) 2020-07-22

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