MA49726A - Formulation d'anticorps anti-cgrp - Google Patents

Formulation d'anticorps anti-cgrp

Info

Publication number
MA49726A
MA49726A MA049726A MA49726A MA49726A MA 49726 A MA49726 A MA 49726A MA 049726 A MA049726 A MA 049726A MA 49726 A MA49726 A MA 49726A MA 49726 A MA49726 A MA 49726A
Authority
MA
Morocco
Prior art keywords
formulation
cgrp antibodies
cgrp
antibodies
Prior art date
Application number
MA049726A
Other languages
English (en)
Inventor
Anant N Sharma
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MA49726A publication Critical patent/MA49726A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591Stabilisation, fragmentation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51Complete heavy chain or Fd fragment, i.e. VH + CH1
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/515Complete light chain, i.e. VL + CL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
MA049726A 2015-06-17 2016-06-08 Formulation d'anticorps anti-cgrp MA49726A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562180905P 2015-06-17 2015-06-17

Publications (1)

Publication Number Publication Date
MA49726A true MA49726A (fr) 2020-06-10

Family

ID=56131672

Family Applications (1)

Application Number Title Priority Date Filing Date
MA049726A MA49726A (fr) 2015-06-17 2016-06-08 Formulation d'anticorps anti-cgrp

Country Status (21)

Country Link
US (3) US11498959B2 (fr)
EP (1) EP3310809A1 (fr)
JP (1) JP6438599B2 (fr)
KR (1) KR102000867B1 (fr)
CN (2) CN107787229A (fr)
AR (1) AR104847A1 (fr)
AU (1) AU2016280555B2 (fr)
BR (1) BR112017023374A2 (fr)
CA (1) CA2984185A1 (fr)
EA (1) EA037580B1 (fr)
HK (1) HK1245813A1 (fr)
IL (2) IL292562A (fr)
JO (1) JO3772B1 (fr)
MA (1) MA49726A (fr)
MX (1) MX2017016199A (fr)
MY (1) MY184266A (fr)
NZ (1) NZ737046A (fr)
TW (1) TWI725973B (fr)
UA (1) UA120881C2 (fr)
WO (1) WO2016205037A1 (fr)
ZA (1) ZA201707324B (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11844720B2 (en) 2011-02-04 2023-12-19 Seed Health, Inc. Method and system to reduce the likelihood of dental caries and halitosis
US11951140B2 (en) 2011-02-04 2024-04-09 Seed Health, Inc. Modulation of an individual's gut microbiome to address osteoporosis and bone disease
US11951139B2 (en) 2015-11-30 2024-04-09 Seed Health, Inc. Method and system for reducing the likelihood of osteoporosis
US11833177B2 (en) 2013-12-20 2023-12-05 Seed Health, Inc. Probiotic to enhance an individual's skin microbiome
US11969445B2 (en) 2013-12-20 2024-04-30 Seed Health, Inc. Probiotic composition and method for controlling excess weight, obesity, NAFLD and NASH
US11839632B2 (en) 2013-12-20 2023-12-12 Seed Health, Inc. Topical application of CRISPR-modified bacteria to treat acne vulgaris
US11826388B2 (en) 2013-12-20 2023-11-28 Seed Health, Inc. Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation
US10556945B2 (en) 2014-03-21 2020-02-11 Teva Pharmaceuticals International Gmbh Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
PT3119431T (pt) 2014-03-21 2024-04-16 Teva Pharmaceuticals Int Gmbh Anticorpos antagonistas dirigidos contra o peptídeo relacionado com o gene da calcitonina e métodos de utilização dos mesmos
PE20191148A1 (es) 2016-09-23 2019-09-02 Teva Pharmaceuticals Int Gmbh Tratamiento de la migrana refractaria
WO2018055573A1 (fr) * 2016-09-23 2018-03-29 Teva Pharmaceuticals International Gmbh Traitement de l'algie vasculaire de la face
EP3589317A1 (fr) 2017-03-02 2020-01-08 Beth Israel Deaconess Medical Center, Inc. Sélection de patients atteints de céphalées présentant une réponse à des anticorps dirigés contre un peptide lié au gène de la calcitonine
TWI754772B (zh) * 2017-09-06 2022-02-11 美商美國禮來大藥廠 用於治療偏頭痛之拉米迪坦(lasmiditan)與cgrp拮抗劑之組合療法
AU2019246983A1 (en) * 2018-04-02 2020-10-29 Amgen Inc. Erenumab compositions and uses thereof
WO2019231800A1 (fr) * 2018-05-31 2019-12-05 Eli Lilly And Company Anticorps anti-cgrp pour le traitement des migraines liées aux menstruations
PE20211707A1 (es) 2019-01-08 2021-09-01 H Lundbeck As Tratamiento agudo y tratamiento rapido de la cefalea usando anticuerpos anticgrp
CN113811326A (zh) * 2019-05-02 2021-12-17 H.隆德贝克有限公司 使用抗cgrp抗体治疗头痛
EP4301362A1 (fr) 2021-03-02 2024-01-10 CGRP Diagnostics GmbH Traitement et/ou réduction de l'apparition de migraine
WO2023026205A1 (fr) 2021-08-24 2023-03-02 Cgrp Diagnostics Gmbh Traitement préventif de la migraine

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2124690C (fr) 1992-10-02 2007-09-11 Thomas Osterberg Composition contenant une preparation du facteur de coagulation viii, methode de preparation et utilisation d'un surfactant comme stabilisateur
TW518219B (en) 1996-04-26 2003-01-21 Chugai Pharmaceutical Co Ltd Erythropoietin solution preparation
AU2002363339B2 (en) * 2001-11-08 2008-02-07 Abbvie Biotechnology Ltd Stable liquid pharmaceutical formulation of IGG antibodies
SI2236154T1 (en) 2003-02-10 2018-08-31 Biogen Ma Inc. THE FORM OF IMUNOGLOBULIN AND THE METHOD OF ITS PREPARATION
KR20070107079A (ko) * 2005-01-28 2007-11-06 와이어쓰 안정화된 액체 폴리펩타이드 제형
GT200600031A (es) 2005-01-28 2006-08-29 Formulacion anticuerpo anti a beta
CA2600836A1 (fr) 2005-03-08 2006-09-14 Pharmacia & Upjohn Company Llc Compositions d'anticorps contre m-csf
KR20140077946A (ko) * 2005-10-13 2014-06-24 휴먼 게놈 사이언시즈, 인코포레이티드 자가항체 양성 질환 환자의 치료에 유용한 방법 및 조성물
US9168286B2 (en) * 2005-10-13 2015-10-27 Human Genome Sciences, Inc. Methods and compositions for use in treatment of patients with autoantibody positive disease
BRPI0618705B8 (pt) 2005-11-14 2021-05-25 Labrys Biologics Inc anticorpos antagonistas humanizados direcionados contra peptídeo relacionado ao gene da calcitonina, composição farmacêutica e uso dos mesmos
US8211649B2 (en) 2006-03-31 2012-07-03 Human Genome Sciences, Inc. Methods of diagnosing and prognosing hodgkin's lymphoma
CN101553504A (zh) * 2006-12-11 2009-10-07 豪夫迈·罗氏有限公司 Aβ抗体胃肠外制剂
JP5419709B2 (ja) * 2007-01-09 2014-02-19 ワイス・エルエルシー 抗il−13抗体製剤およびその使用
KR20090113340A (ko) * 2007-03-22 2009-10-29 임클론 엘엘씨 안정한 항체 제제
KR101540823B1 (ko) 2007-03-30 2015-07-30 메디뮨 엘엘씨 항체 제제
KR20100016661A (ko) * 2007-04-18 2010-02-12 얀센 알츠하이머 이뮤노테라피 대뇌 아밀로이드 혈관병증의 예방 및 치료
HUE036126T2 (hu) * 2008-09-19 2018-06-28 Pfizer Stabil folyékony ellenanyag kiszerelés
CA2738243C (fr) 2008-10-29 2020-09-29 Wyeth Llc Formulations de molecules de liaison d'antigene monodomaines
JP5933975B2 (ja) * 2008-11-12 2016-06-15 メディミューン,エルエルシー 抗体製剤
NZ606283A (en) * 2008-11-28 2014-08-29 Abbvie Inc Stable antibody compositions and methods for stabilizing same
EP2196476A1 (fr) 2008-12-10 2010-06-16 Novartis Ag Formulation d'anticorps
WO2010102276A2 (fr) * 2009-03-06 2010-09-10 Medimmune, Llc Formulations d'anticorps humanisés anti-cd19
JO3417B1 (ar) * 2010-01-08 2019-10-20 Regeneron Pharma الصيغ المستقرة التي تحتوي على الأجسام المضادة لمضاد مستقبل( interleukin-6 (il-6r
JO3330B1 (ar) * 2010-06-10 2019-03-13 Lilly Co Eli الأجسام المضادة cgrp
DK3246044T3 (da) * 2010-08-23 2021-01-18 Wyeth Llc Stabile formuleringer af Neisseria-meningitidis-RLP2086-antigener
EP2691112B1 (fr) * 2011-03-31 2018-05-23 Merck Sharp & Dohme Corp. Formulations stables d'anticorps dirigés contre le récepteur humain pd-1 de la mort programmée et traitements associés
CA2836649C (fr) * 2011-05-20 2020-06-23 Alderbio Holdings Llc Compositions comprenant des anticorps anti-cgrp et leur utilisation
KR20140084253A (ko) 2011-10-24 2014-07-04 애브비 인코포레이티드 Tnf에 대한 면역결합제
US20140227250A1 (en) * 2012-08-23 2014-08-14 Merck Sharp & Dohme Corp. Stable formulations of antibodies to tslp
EP2948473A1 (fr) * 2013-01-24 2015-12-02 GlaxoSmithKline Intellectual Property Development Limited Protéines de liaison à l'antigène tnf-alpha
PT3119431T (pt) * 2014-03-21 2024-04-16 Teva Pharmaceuticals Int Gmbh Anticorpos antagonistas dirigidos contra o peptídeo relacionado com o gene da calcitonina e métodos de utilização dos mesmos

Also Published As

Publication number Publication date
IL255443B (en) 2022-06-01
MY184266A (en) 2021-03-30
UA120881C2 (uk) 2020-02-25
US20180134772A1 (en) 2018-05-17
AU2016280555B2 (en) 2018-11-15
US20220112277A1 (en) 2022-04-14
US11498959B2 (en) 2022-11-15
WO2016205037A1 (fr) 2016-12-22
KR20180002858A (ko) 2018-01-08
CA2984185A1 (fr) 2016-12-22
KR102000867B1 (ko) 2019-07-16
CN114948847A (zh) 2022-08-30
BR112017023374A2 (pt) 2018-07-24
IL292562A (en) 2022-06-01
HK1245813A1 (zh) 2018-08-31
JP2018517727A (ja) 2018-07-05
MX2017016199A (es) 2018-03-01
JP6438599B2 (ja) 2018-12-19
TW201711697A (zh) 2017-04-01
EP3310809A1 (fr) 2018-04-25
EA037580B1 (ru) 2021-04-16
TWI725973B (zh) 2021-05-01
NZ737046A (en) 2019-09-27
IL255443A0 (en) 2017-12-31
EA201792359A1 (ru) 2018-05-31
CN107787229A (zh) 2018-03-09
JO3772B1 (ar) 2021-01-31
AU2016280555A1 (en) 2017-11-16
US20230159628A1 (en) 2023-05-25
ZA201707324B (en) 2020-01-29
AR104847A1 (es) 2017-08-16

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