MA47499A - Anticorps anti-tau et leurs procédés d'utilisation - Google Patents
Anticorps anti-tau et leurs procédés d'utilisationInfo
- Publication number
- MA47499A MA47499A MA047499A MA47499A MA47499A MA 47499 A MA47499 A MA 47499A MA 047499 A MA047499 A MA 047499A MA 47499 A MA47499 A MA 47499A MA 47499 A MA47499 A MA 47499A
- Authority
- MA
- Morocco
- Prior art keywords
- tau
- bodies
- methods
- tau bodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/35—Valency
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/54—F(ab')2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/71—Decreased effector function due to an Fc-modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762460642P | 2017-02-17 | 2017-02-17 | |
US201762583400P | 2017-11-08 | 2017-11-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA47499A true MA47499A (fr) | 2019-12-25 |
Family
ID=61563475
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA047499A MA47499A (fr) | 2017-02-17 | 2018-02-15 | Anticorps anti-tau et leurs procédés d'utilisation |
Country Status (14)
Country | Link |
---|---|
US (1) | US11370832B2 (fr) |
EP (1) | EP3583123A1 (fr) |
JP (1) | JP2020508054A (fr) |
KR (1) | KR20190134997A (fr) |
CN (1) | CN110520440A (fr) |
AU (1) | AU2018221049A1 (fr) |
BR (1) | BR112019017021A2 (fr) |
CA (1) | CA3053379A1 (fr) |
IL (1) | IL268658A (fr) |
MA (1) | MA47499A (fr) |
MX (1) | MX2019009817A (fr) |
SG (1) | SG11201907422RA (fr) |
TW (1) | TW201843175A (fr) |
WO (1) | WO2018152359A1 (fr) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
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AU2014248515B2 (en) | 2013-03-13 | 2019-03-07 | Prothena Biosciences Limited | Tau immunotherapy |
KR102471787B1 (ko) | 2016-05-02 | 2022-11-29 | 프로테나 바이오사이언시즈 리미티드 | 타우 인식 항체 |
ES2933491T3 (es) | 2016-05-02 | 2023-02-09 | Prothena Biosciences Ltd | Inmunoterapia tau |
AU2018221731C1 (en) | 2017-02-17 | 2021-11-18 | Denali Therapeutics Inc. | Engineered transferrin receptor binding polypeptides |
CA3061516A1 (fr) | 2017-05-02 | 2018-11-08 | Prothena Biosciences Limited | Anticorps reconnaissant la proteine tau |
MX2020002918A (es) | 2017-10-02 | 2020-07-22 | Denali Therapeutics Inc | Proteinas de fusion que comprenden enzimas de terapia de reemplazo de enzimas. |
TWI750419B (zh) * | 2017-10-16 | 2021-12-21 | 日商衛材R&D企管股份有限公司 | 抗tau抗體及其用途 |
WO2019094576A1 (fr) * | 2017-11-08 | 2019-05-16 | Denali Therapeutics Inc. | Anticorps bispécifiques bace-tau |
WO2019094608A1 (fr) | 2017-11-08 | 2019-05-16 | Denali Therapeutics Inc. | Anticorps anti-bace1 et leurs procédés d'utilisation |
MX2021001711A (es) * | 2018-08-16 | 2021-05-27 | Denali Therapeutics Inc | Proteínas biespecíficas modificadas. |
AU2019326545A1 (en) * | 2018-08-22 | 2021-03-11 | Denali Therapeutics Inc. | Anti-HER2 polypeptides and methods of use thereof |
WO2020180819A1 (fr) | 2019-03-03 | 2020-09-10 | Prothena Biosciences Limited | Anticorps reconnaissant la protéine tau |
WO2020242963A1 (fr) * | 2019-05-31 | 2020-12-03 | Eli Lilly And Company | Composés et procédés ciblant la protéine tau humaine |
GB2585252A (en) * | 2019-07-05 | 2021-01-06 | Gen2 Neuroscience Ltd | Tau epitope and binding molecules |
CN114981297A (zh) | 2019-12-23 | 2022-08-30 | 戴纳立制药公司 | 颗粒蛋白前体变体 |
CN114930170A (zh) | 2020-01-02 | 2022-08-19 | 豪夫迈·罗氏有限公司 | 用于测定脑中的治疗性抗体量的方法 |
KR20220131246A (ko) * | 2020-01-13 | 2022-09-27 | 데날리 테라퓨틱스 인크. | 항-trem2 항체 및 이의 사용 방법 |
IL302029A (en) | 2020-10-14 | 2023-06-01 | Denali Therapeutics Inc | Fusion proteins containing sulfoglucosamine sulfohydrolase enzymes and methods thereof |
WO2023041805A1 (fr) | 2021-09-20 | 2023-03-23 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Procédés pour l'amélioration de l'efficacité d'une thérapie par inhibiteur de hdac et la prédiction de la réponse à un traitement comprenant un inhibiteur de hdac |
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WO2018085653A1 (fr) | 2016-11-04 | 2018-05-11 | The Regents Of The University Of California | Compositions ciblant la protéine tau à triple répétition pour le traitement de troubles neurodégénératifs, et leurs procédés de fabrication et d'utilisation |
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CR20230163A (es) | 2016-12-07 | 2023-07-06 | Genentech Inc | ANTICUERPOS ANTITAU Y MÉTODOS DE USO (Divisional 2019-0271) |
AU2017373884A1 (en) | 2016-12-07 | 2019-05-30 | Ac Immune Sa | Anti-tau antibodies and methods of their use |
CN110267985B (zh) | 2017-01-04 | 2023-05-23 | H.隆德贝克有限公司 | 用于治疗眼科疾病的特异性针对过度磷酸化τ蛋白的抗体 |
JP2018139530A (ja) | 2017-02-27 | 2018-09-13 | 帝人ファーマ株式会社 | 認知症治療又は予防のためのヒト化抗体及びその製造方法、並びにそれを用いた認知症治療剤又は予防剤 |
JOP20180021A1 (ar) | 2017-03-16 | 2019-01-30 | Janssen Biotech Inc | الأجسام المضادة لتكتلات خيوط بروتين تاو (tau) الحلزونية المزدوجة واستخداماتها |
US11249093B2 (en) | 2017-03-28 | 2022-02-15 | Janssen Vaccines & Prevention B.V. | Methods for detection of Tau protein aggregation modulating compounds |
KR20190133191A (ko) | 2017-03-28 | 2019-12-02 | 얀센 백신스 앤드 프리벤션 비.브이. | 타우에 특이적으로 결합하는 결합 분자 |
TW202400231A (zh) | 2017-03-28 | 2024-01-01 | 美商建南德克公司 | 治療神經退化性疾病之方法 |
JP7278960B2 (ja) | 2017-03-28 | 2023-05-22 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 新規タウ種 |
CA3061516A1 (fr) | 2017-05-02 | 2018-11-08 | Prothena Biosciences Limited | Anticorps reconnaissant la proteine tau |
JP2020529394A (ja) | 2017-06-16 | 2020-10-08 | ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company | タウオパチーを治療するための組成物及び方法 |
US10662246B2 (en) | 2017-07-10 | 2020-05-26 | New York University | Monoclonal antibody to treat alzheimer's disease, prion disease, frontotemporal dementias and traumatic brain injury/chronic traumatic encephalopathy |
EP4310496A2 (fr) | 2017-07-12 | 2024-01-24 | Dana-Farber Cancer Institute, Inc. | Composés pour la dégradation de la protéine tau |
MX2020001171A (es) | 2017-08-01 | 2020-03-12 | Amgen Inc | Sistemas y metodos para realizar un ensayo de glicanos en tiempo real de una muestra. |
TWI750419B (zh) | 2017-10-16 | 2021-12-21 | 日商衛材R&D企管股份有限公司 | 抗tau抗體及其用途 |
WO2019094576A1 (fr) | 2017-11-08 | 2019-05-16 | Denali Therapeutics Inc. | Anticorps bispécifiques bace-tau |
-
2018
- 2018-02-15 EP EP18708795.2A patent/EP3583123A1/fr not_active Withdrawn
- 2018-02-15 SG SG11201907422RA patent/SG11201907422RA/en unknown
- 2018-02-15 MX MX2019009817A patent/MX2019009817A/es unknown
- 2018-02-15 MA MA047499A patent/MA47499A/fr unknown
- 2018-02-15 WO PCT/US2018/018415 patent/WO2018152359A1/fr unknown
- 2018-02-15 JP JP2019545364A patent/JP2020508054A/ja active Pending
- 2018-02-15 CA CA3053379A patent/CA3053379A1/fr not_active Abandoned
- 2018-02-15 CN CN201880024720.8A patent/CN110520440A/zh active Pending
- 2018-02-15 AU AU2018221049A patent/AU2018221049A1/en not_active Abandoned
- 2018-02-15 KR KR1020197027036A patent/KR20190134997A/ko unknown
- 2018-02-15 BR BR112019017021A patent/BR112019017021A2/pt not_active Application Discontinuation
- 2018-02-21 TW TW107105837A patent/TW201843175A/zh unknown
-
2019
- 2019-08-12 IL IL26865819A patent/IL268658A/en unknown
- 2019-08-16 US US16/543,367 patent/US11370832B2/en active Active
Also Published As
Publication number | Publication date |
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KR20190134997A (ko) | 2019-12-05 |
US11370832B2 (en) | 2022-06-28 |
BR112019017021A2 (pt) | 2020-04-14 |
JP2020508054A (ja) | 2020-03-19 |
US20200216522A1 (en) | 2020-07-09 |
EP3583123A1 (fr) | 2019-12-25 |
WO2018152359A1 (fr) | 2018-08-23 |
IL268658A (en) | 2019-10-31 |
MX2019009817A (es) | 2019-11-21 |
AU2018221049A1 (en) | 2019-09-19 |
CA3053379A1 (fr) | 2018-08-23 |
TW201843175A (zh) | 2018-12-16 |
SG11201907422RA (en) | 2019-09-27 |
CN110520440A (zh) | 2019-11-29 |
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