MA41941A - Procédé de purification de protéines - Google Patents

Procédé de purification de protéines

Info

Publication number
MA41941A
MA41941A MA041941A MA41941A MA41941A MA 41941 A MA41941 A MA 41941A MA 041941 A MA041941 A MA 041941A MA 41941 A MA41941 A MA 41941A MA 41941 A MA41941 A MA 41941A
Authority
MA
Morocco
Prior art keywords
purification process
protein purification
protein
purification
Prior art date
Application number
MA041941A
Other languages
English (en)
Inventor
Sam Philip Heywood
Gavin Barry Wild
Original Assignee
Ucb Biopharma Sprl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Biopharma Sprl filed Critical Ucb Biopharma Sprl
Publication of MA41941A publication Critical patent/MA41941A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/22Affinity chromatography or related techniques based upon selective absorption processes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065Purification, fragmentation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/624Disulfide-stabilized antibody (dsFv)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
MA041941A 2015-04-22 2016-04-20 Procédé de purification de protéines MA41941A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1506868.7A GB201506868D0 (en) 2015-04-22 2015-04-22 Method for protein purification

Publications (1)

Publication Number Publication Date
MA41941A true MA41941A (fr) 2018-02-28

Family

ID=53299017

Family Applications (1)

Application Number Title Priority Date Filing Date
MA041941A MA41941A (fr) 2015-04-22 2016-04-20 Procédé de purification de protéines

Country Status (19)

Country Link
US (2) US10927164B2 (fr)
EP (1) EP3286205A1 (fr)
JP (2) JP6866300B2 (fr)
KR (1) KR102675400B1 (fr)
CN (1) CN107636012B (fr)
AR (1) AR104358A1 (fr)
AU (1) AU2016251223B2 (fr)
BR (1) BR112017022073A2 (fr)
CA (1) CA2983057A1 (fr)
CL (1) CL2017002614A1 (fr)
CO (1) CO2017010631A2 (fr)
EA (1) EA201792328A1 (fr)
GB (1) GB201506868D0 (fr)
IL (1) IL254883B (fr)
MA (1) MA41941A (fr)
MX (1) MX2017013333A (fr)
MY (1) MY189854A (fr)
SG (1) SG11201708256YA (fr)
WO (1) WO2016169992A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9657055B2 (en) * 2011-11-30 2017-05-23 Ge Healthcare Bioprocess R&D Ab Affinity chromatography matrix
GB201506869D0 (en) 2015-04-22 2015-06-03 Ucb Biopharma Sprl Method
GB201506870D0 (en) 2015-04-22 2015-06-03 Ucb Biopharma Sprl Method
CN108085358A (zh) * 2018-02-08 2018-05-29 保定冀中药业有限公司 一种犬细小病毒单克隆抗体IgG2b-Fab片段的制备方法
EP4007771A1 (fr) 2019-08-02 2022-06-08 UCB Biopharma SRL Procédés de purification d'anticorps
GB201919058D0 (en) * 2019-12-20 2020-02-05 Ucb Biopharma Sprl Multi-specific antibodies
BR112022011993A2 (pt) * 2019-12-26 2022-09-20 Abl Bio Inc Método para purificar peptídeo biologicamente ativo usando cromatografia de afinidade de proteína a
GB202109246D0 (en) * 2021-06-28 2021-08-11 Cytiva Bioprocess R & D Ab A method of separating bispecific antibodies

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5429746A (en) 1994-02-22 1995-07-04 Smith Kline Beecham Corporation Antibody purification
AU777005B2 (en) * 1999-05-15 2004-09-30 University Of California, San Diego Protein A based binding domains with desirable activities
CZ20031983A3 (cs) * 2000-12-29 2005-07-13 Savient Pharmaceuticals, Inc. Specifické protilátky pro selektivní léčbu rakoviny
JPWO2004087761A1 (ja) * 2003-03-31 2006-07-27 麒麟麦酒株式会社 ヒトモノクローナル抗体およびヒトポリクローナル抗体の精製
US20110144311A1 (en) * 2008-08-14 2011-06-16 Rebecca Chmielowski Methods for purifying antibodies using protein a affinity chromatography
JP5782385B2 (ja) 2009-02-17 2015-09-24 ユーシービー ファーマ ソシエテ アノニム ヒトox40に対する特異性を有する抗体分子
CN103189390A (zh) * 2010-11-01 2013-07-03 帝斯曼知识产权资产管理有限公司 单一单元离子交换色谱抗体纯化
WO2012074463A1 (fr) 2010-11-29 2012-06-07 Ge Healthcare Bio-Sciences Ab Matrice de chromatographie d'affinité
SG11201401649VA (en) 2011-11-11 2014-07-30 Ucb Pharma Sa Albumin binding antibodies and binding fragments thereof
UA112203C2 (uk) 2011-11-11 2016-08-10 Юсб Фарма С.А. Злитий білок біоспецифічного антитіла, який зв'язується з ox40 людини та сироватковим альбуміном людини
WO2013119966A2 (fr) * 2012-02-10 2013-08-15 Genentech, Inc. Anticorps et autres hétéromultimères monocaténaires
GB201223276D0 (en) 2012-12-21 2013-02-06 Ucb Pharma Sa Antibodies and methods of producing same
US9493563B2 (en) * 2013-11-04 2016-11-15 Glenmark Pharmaceuticals S.A. Production of T cell retargeting hetero-dimeric immunoglobulins
GB201506870D0 (en) 2015-04-22 2015-06-03 Ucb Biopharma Sprl Method
GB201506869D0 (en) 2015-04-22 2015-06-03 Ucb Biopharma Sprl Method

Also Published As

Publication number Publication date
US10927164B2 (en) 2021-02-23
SG11201708256YA (en) 2017-11-29
IL254883B (en) 2021-09-30
EP3286205A1 (fr) 2018-02-28
GB201506868D0 (en) 2015-06-03
AU2016251223A1 (en) 2017-10-26
US20210171609A1 (en) 2021-06-10
CN107636012A (zh) 2018-01-26
KR102675400B1 (ko) 2024-06-13
BR112017022073A2 (pt) 2018-08-14
JP2021066734A (ja) 2021-04-30
KR20170139131A (ko) 2017-12-18
CL2017002614A1 (es) 2018-04-27
AU2016251223B2 (en) 2021-12-09
MX2017013333A (es) 2018-02-19
AR104358A1 (es) 2017-07-12
CO2017010631A2 (es) 2018-01-05
WO2016169992A1 (fr) 2016-10-27
US20180100007A1 (en) 2018-04-12
CN107636012B (zh) 2022-08-02
JP6866300B2 (ja) 2021-04-28
EA201792328A1 (ru) 2018-05-31
JP2018520089A (ja) 2018-07-26
IL254883A0 (en) 2017-12-31
CA2983057A1 (fr) 2016-10-27
MY189854A (en) 2022-03-14

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