MA39898B1 - Composés 4-amino-imidazoquinoline - Google Patents
Composés 4-amino-imidazoquinolineInfo
- Publication number
- MA39898B1 MA39898B1 MA39898A MA39898A MA39898B1 MA 39898 B1 MA39898 B1 MA 39898B1 MA 39898 A MA39898 A MA 39898A MA 39898 A MA39898 A MA 39898A MA 39898 B1 MA39898 B1 MA 39898B1
- Authority
- MA
- Morocco
- Prior art keywords
- amino
- imidazoquinoline compounds
- compounds
- imidazoquinoline
- medicaments
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
Cette invention concerne des composés de 4-amino-imidazoquinoline de formule (i) dans laquelle r1 à r4 sont tels que définis dans la description et dans les revendications, ainsi que des sels pharmaceutiquement acceptables de ceux-ci. Ces composés sont des agonistes du tlr et peuvent donc être utiles comme médicaments destinés à traiter des maladies telles que le cancer ou des maladies infectieuses.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP14165349 | 2014-04-22 | ||
PCT/EP2015/058465 WO2015162075A1 (fr) | 2014-04-22 | 2015-04-20 | Composés de 4-amino-imidazoquinoline |
Publications (1)
Publication Number | Publication Date |
---|---|
MA39898B1 true MA39898B1 (fr) | 2020-08-31 |
Family
ID=50489008
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA39898A MA39898B1 (fr) | 2014-04-22 | 2015-04-20 | Composés 4-amino-imidazoquinoline |
Country Status (22)
Country | Link |
---|---|
US (2) | US9334268B2 (fr) |
EP (1) | EP3134402B1 (fr) |
JP (1) | JP6367366B2 (fr) |
KR (1) | KR101905292B1 (fr) |
CN (1) | CN106232599B (fr) |
AR (1) | AR100137A1 (fr) |
BR (1) | BR112016017261B1 (fr) |
CA (1) | CA2938280C (fr) |
DK (1) | DK3134402T3 (fr) |
ES (1) | ES2804101T3 (fr) |
HR (1) | HRP20201043T1 (fr) |
HU (1) | HUE049656T2 (fr) |
LT (1) | LT3134402T (fr) |
MA (1) | MA39898B1 (fr) |
MX (1) | MX2016013689A (fr) |
PL (1) | PL3134402T3 (fr) |
PT (1) | PT3134402T (fr) |
RS (1) | RS60430B1 (fr) |
RU (1) | RU2698902C2 (fr) |
SI (1) | SI3134402T1 (fr) |
TW (1) | TWI607007B (fr) |
WO (1) | WO2015162075A1 (fr) |
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EP3199159B1 (fr) | 2009-08-07 | 2019-04-10 | GlaxoSmithKline Biologicals S.A. | Dérivés d'oxoadénine lipidés |
WO2011068233A1 (fr) | 2009-12-03 | 2011-06-09 | Dainippon Sumitomo Pharma Co., Ltd. | Imidazoquinolines agissant par l'intermédiaire des récepteurs de type toll (tlr) |
WO2011139348A2 (fr) | 2010-04-30 | 2011-11-10 | The Regents Of The University Of California | Utilisations de conjugués phospholipidiques d'agonistes synthétiques de tlr7 |
WO2012045090A2 (fr) | 2010-10-01 | 2012-04-05 | Ventirx Pharmaceuticals, Inc. | Utilisation thérapeutique d'un agoniste de tlr, et polythérapie |
WO2012066336A1 (fr) | 2010-11-19 | 2012-05-24 | Astrazeneca Ab | Composés de benzylamine à titre d'agonistes du récepteur toll-like 7 |
BR112013031039B1 (pt) | 2011-06-03 | 2020-04-28 | 3M Innovative Properties Co | compostos de hidrazino 1h-imidazoquinolina-4-aminas, conjugados feitos destes compostos, composição e composição farmacêutica compreendendo ditos compostos e conjugados, usos dos mesmos e método de fabricação do conjugado |
WO2012167801A1 (fr) | 2011-06-07 | 2012-12-13 | Uglovsky Sergey Evgenievich | Installation à impulsions pour transformer une énergie thermique à faible potentiel en énergie électrique |
US9034336B2 (en) | 2011-08-30 | 2015-05-19 | Regents Of The University Of Minnesota | Immunomodulators and immunomodulator conjugates |
IN2014CN04251A (fr) * | 2011-11-09 | 2015-07-17 | Ascend Biopharmaceuticals Ltd | |
WO2013166110A1 (fr) | 2012-05-02 | 2013-11-07 | Yale University | Molécules de recrutement d'anticorps conjugués à un agoniste de tlr) |
-
2015
- 2015-04-20 CA CA2938280A patent/CA2938280C/fr active Active
- 2015-04-20 PT PT157168246T patent/PT3134402T/pt unknown
- 2015-04-20 RS RS20200734A patent/RS60430B1/sr unknown
- 2015-04-20 BR BR112016017261-2A patent/BR112016017261B1/pt active IP Right Grant
- 2015-04-20 MX MX2016013689A patent/MX2016013689A/es unknown
- 2015-04-20 MA MA39898A patent/MA39898B1/fr unknown
- 2015-04-20 HU HUE15716824A patent/HUE049656T2/hu unknown
- 2015-04-20 EP EP15716824.6A patent/EP3134402B1/fr active Active
- 2015-04-20 RU RU2016144386A patent/RU2698902C2/ru active
- 2015-04-20 JP JP2016564006A patent/JP6367366B2/ja active Active
- 2015-04-20 CN CN201580020712.2A patent/CN106232599B/zh active Active
- 2015-04-20 SI SI201531273T patent/SI3134402T1/sl unknown
- 2015-04-20 AR ARP150101179A patent/AR100137A1/es active IP Right Grant
- 2015-04-20 ES ES15716824T patent/ES2804101T3/es active Active
- 2015-04-20 KR KR1020167032523A patent/KR101905292B1/ko active IP Right Grant
- 2015-04-20 LT LTEP15716824.6T patent/LT3134402T/lt unknown
- 2015-04-20 WO PCT/EP2015/058465 patent/WO2015162075A1/fr active Application Filing
- 2015-04-20 DK DK15716824.6T patent/DK3134402T3/da active
- 2015-04-20 PL PL15716824T patent/PL3134402T3/pl unknown
- 2015-04-21 TW TW104112767A patent/TWI607007B/zh active
- 2015-04-22 US US14/692,968 patent/US9334268B2/en active Active
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2016
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- 2020-07-01 HR HRP20201043TT patent/HRP20201043T1/hr unknown
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Publication number | Publication date |
---|---|
ES2804101T3 (es) | 2021-02-03 |
RU2698902C2 (ru) | 2019-09-02 |
KR101905292B1 (ko) | 2018-11-21 |
JP6367366B2 (ja) | 2018-08-01 |
TWI607007B (zh) | 2017-12-01 |
US9334268B2 (en) | 2016-05-10 |
RU2016144386A3 (fr) | 2018-11-27 |
CA2938280C (fr) | 2022-07-12 |
RS60430B1 (sr) | 2020-07-31 |
DK3134402T3 (da) | 2020-07-20 |
US9447097B2 (en) | 2016-09-20 |
CN106232599B (zh) | 2018-11-16 |
HUE049656T2 (hu) | 2020-10-28 |
WO2015162075A1 (fr) | 2015-10-29 |
TW201544505A (zh) | 2015-12-01 |
US20160222010A1 (en) | 2016-08-04 |
JP2017513883A (ja) | 2017-06-01 |
RU2016144386A (ru) | 2018-05-22 |
CA2938280A1 (fr) | 2015-10-29 |
AR100137A1 (es) | 2016-09-14 |
HRP20201043T1 (hr) | 2020-10-16 |
LT3134402T (lt) | 2020-07-10 |
MX2016013689A (es) | 2017-01-20 |
SI3134402T1 (sl) | 2020-08-31 |
PL3134402T3 (pl) | 2020-11-02 |
KR20160138317A (ko) | 2016-12-02 |
CN106232599A (zh) | 2016-12-14 |
PT3134402T (pt) | 2020-07-02 |
BR112016017261B1 (pt) | 2022-04-19 |
US20150299194A1 (en) | 2015-10-22 |
BR112016017261A8 (pt) | 2020-06-16 |
EP3134402A1 (fr) | 2017-03-01 |
EP3134402B1 (fr) | 2020-05-06 |
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